Inside Out Quality Aaron & Diane

In this intermission, we interview Jenifer Fjelstad. Jeni is an undergraduate at Augustana University in Sioux Falls and supports the podcast through her internship. Learn more about her on this intermission! 

Primodos, a hormone-based pregnancy test, was given to women between 1959 and 1978. Its development occurred before GLP and before standardized testing for teratogenesis (causing birth defects).  There are data and suspicions that it caused birth defects, but more questions remain.

This episode of Inside Out Quality explores the story of this in vivo diagnostic with Dr. Neil Vargesson, from the University of Aberdeen, Scotland, UK. Learn another reason for the importance of Good Laboratory Practices and why pre-clinical studies are key to keeping people safe.

To learn more about Dr. Vargesson's research, visit his site here: Link   

Dr. Vargesson's research  publication discussed on this show: Link 
 

Hailey Nold joined Inside Out Quality for season two to help with planning, research, and locating guests. Learn more about Hailey and how she made our work so much fun on this intermission!

How did a formulation change, turn a life saving drug into a poison? How did tragedy push US lawmakers into passing a new act to regulate Food, Drugs, and Cosmetics? Historian Vanessa Burrows with the FDA joins us to share the story of Elixir Sulfanilamide and the FD&C Act of 1938. This is a story of what can go wrong when morality, science, and businesses are done wrong. 

To learn more about the FDA's history check out these sites:
 
www.fda.gov/history
Frances Kelsey’s oral history 
Elixir sulfanilamide sample bottle
Oral Histories 
Video blogs
A synopsis of the Elixir Sulfanilamide tragedy

In season 2 we are bringing you intermissions: short interviews with local professionals and those that help make this podcast happen. We hope you enjoy!

In this intermission, I interview Diane Cox and Nate Poeppel about one of things they have in common: a vegan diet. Join us as we discuss how they chose this diet, why they stick with it, and strategies they employ living in the Midwest. 

In this episode we explore the tragic failure in human factors engineering on the Boeing 737 MAX and why early incorporation of the user’s needs and limitations is key to developing better, safer products. Dr. Mica Endsley, former Chief Scientist of the Air Force and founder of SA Technologies, joins us to discuss Human Factors Engineering and what we can learn from the 737 MAX tragedies.  

Human Factors & Ergonomics Society: www.hfes.org