IRRAS Radio IRRAS Radio

Dr. Brandmeir, a neurosurgeon from WVU Hospital and the WVU Rockefeller Neuroscience Institute, presents his early experience utilizing IRRAlfow and demonstrates the positive clinical outcomes seen with his case reviews.
Presentation Outline:
- Why do we need a better EVD?
- What is IRRAflow, and how does it work?
- How he uses IRRAflow in the ICU?
- What are some outcomes that you can expect with IRRAflow?
Case Reviews: - cSDH treated with IRRAflow
- IVH treated with EVD
- IVH treated with IRRAflow and tPA
- IVH with IPH treated with IRRAflow and tPA
- IVH treated with IRRAflow and tPA with endoscopic photos
- Abscess treated with IRRAflow with antibiotic

Intracranial abscesses are rare lesions with an incidence estimated at 1500-2500 cases per year in the United States. Widespread use of neuroimaging has led to rapid diagnosis, decreasing the mortality rate from 40-50% to approximately 20. Treatment options include systemic antibiotic therapy, needle aspiration through a burr hole, and open craniotomy for excision.
The recently introduced IRRAflow self-irrigating catheter system has been used to treat subdural hematomas and intraventricular hemorrhages although research into other applications for this technology is still ongoing.
Dr. Ryan Hess, neurosurgeon form Buffalo General Hospital presents a case review of an intracranial abscess treated via open craniotomy and IRRAflow placement allowing for continuous irrigation and drainage of the abscess.
Read more here: https://www.cureus.com/articles/68647...

Intraventricular hemorrhage (IVH) is a devastating neurosurgical condition associated with high rates of morbidity and mortality. It can occur as the result of several pathologies and typically presents with mental status changes, neurologic deficits, seizures, headaches, and decreased Glasgow Coma Scale score. These patients are often treated with placement of an external ventricular drain, which helps decrease the clot burden; however, they commonly clot off leading to multiple exchanges.
Dr. Ryan Hess, neurosurgeon form Buffalo General Hospital presents a case review in which drainage, irrigation, and fibrinolytic (DRIFT) therapy using IRRAflow® (IRRAS) irrigating catheter was used to treat a patient with severe IVH secondary to aneurysmal subarachnoid hemorrhage.
Read more here: https://www.cureus.com/articles/57776...

Dr. Behnam Rezai Jahromi a neurosurgeon from Helsinki University Hospital presents his clinical experience utilizing IRRAflow to treat IVH and Ventriculitis patients with drug delivery.

Neurosurgeon Dr. Kurt Yaeger, from Mt. Sinai Hospital in New York, New York, shares insight to being a healthcare worker on the front lines of the COVID-19 pandemic and provides an overview of his recent publication in World Neurosurgery, Patterns of Health Care Costs Due to External Ventricular Drain Infections.
Additional Information about this study can be found below.
Background: External ventricular drain (EVD) infections are a significant cause of morbidity among neurosurgical patients and have been correlated with increased length of hospital stay and longer requirements for intensive care. To date, no studies have examined the financial impact of EVD infections.
Methods: Patients who underwent EVD placement between December 2010 and January 2016 were included in the study. Clinical records were retrospectively reviewed and health care cost data were obtained from the hospital's finance department. Clinical information included patient demographics, details from the hospital course, and outcomes. Total costs, direct/indirect, and fixed/variable costs were analyzed for every patient.
Results: Over the 5-year study period, 246 EVDs were placed in 243 patients with an overall infection rate of 9.9% (N = 24). The median EVD duration for infected versus noninfected patients was 19 and 9 days, respectively (P 0.0001). Median length of intensive care unit stay also was increased for patients with EVD infection (30 days vs. 13 days, P 0.0001). Total health care costs were significantly greater for infected patients (US$ 168,692 vs. US$ 83,919, P 0.0001). This trend was comparable for all other cost subtypes, including fixed-direct costs, fixed-indirect costs, variable direct costs, and variable-indirect costs.
Conclusions: EVD infection has a substantial effect on clinical morbidity and healthcare costs. These results demonstrate the imperative need to improve EVD infection prevention, particularly in the setting of a value-based health care system.

IRRAflow was selected as the 2019 winner of CONNECT's Most Innovative New Product award in the medical device category. CONNECT, a premier nonprofit helping entrepreneurs with innovative startups in the technology and life sciences sectors, has been celebrating innovation leaders in the broader San Diego area for the last thirty-two-years.
IRRAflow, the company's initial commercial product, has a unique mechanism of action that addresses the complications associated with the current methods of managing intracranial fluid by using a dual-lumen catheter that combines automated irrigation, controlled drainage, and continuous ICP monitoring, all into one system.