LabReflex

Christopher Zahner, MD

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A conversational podcast about more innovative diagnostics, lab insights, and the future of clinical testing. Hosted by Dr. Christopher Zahner, LabReflex brings expert voices, industry trends, and practical conversations straight from the laboratory bench to your brain.

-1 ДН.

Inspection Prep

Pre-Inspection Prep: Readiness Without Panic Readiness isn’t a binder. It’s a system. Inspection anxiety has a familiar rhythm. Suddenly policies are being printed. QC logs are double-checked. Everyone asks where the competency files are. It feels urgent — even if the inspector hasn’t arrived yet. But what does it actually mean to be “ready”? In this episode, we unpack a simple but powerful idea: inspection readiness is not about perfection. It’s about stability. The goal isn’t zero findings. The goal is a lab that behaves predictably under observation — without panic. Weekly Highlights Flu Activity: Systems Under Real-World Stress Influenza activity remains elevated across the U.S., with pediatric impact especially significant this season. Flu isn’t just a public health story — it’s an operational stress test. Volume surges reveal whether workflows are resilient or fragile. Readiness shows up long before inspection week. State-Level Lab Access Policy (Virginia Example) Legislation aimed at preventing insurer steering of specimens raises broader questions about specimen routing, turnaround time, and documentation. Policy shifts can change workflow architecture — and readiness requires anticipating those changes. FDA Reclassification of Diagnostic Systems The FDA is evaluating reclassification of certain diagnostic test categories, including nucleic acid-based systems. Regulatory categories evolve quietly — but when they do, validation expectations and inspection focus can shift with them. Clarification Around “Immediate Jeopardy” Survey language around Immediate Jeopardy is becoming more explicit. The emphasis is clear: inspectors are evaluating system control and risk of patient harm — not cosmetic compliance. Deep Dive: What “Ready” Actually Means 1. The Myth of the Perfect Lab No functioning laboratory is static. Staff turnover, LIS changes, test expansion, and surge pressure all introduce variation. The objective is not flawlessness — it is transparency and correction. Panic prep often introduces more risk than it removes: Last-minute rewritingCosmetic log cleanupBlame-driven cultureReadiness is cultural stability, not visual polish. 2. Internal Audits That Actually Help An audit should answer one question: If someone observed this process today, would it behave coherently? High-yield audit targets include: Specimen receiving and accessioningAdd-on workflowsCorrected reportsCritical value communicationDowntime proceduresSend-outs and handoffsLabs rarely fail at chemistry. They fail at seams. Repeated issues signal design flaws — not individual weakness. 3. Mock Inspections: Tool or Threat? Mock inspections should normalize observation — not amplify fear. When run well, mocks build composure: Answering only what’s askedRetrieving documentation calmlyDemonstrating normal workflowWhen run poorly, they create concealment and brittleness. A mock that increases fear decreases readiness. Micro-mocks — short, focused, routine — are often more effective than annual large-scale rehearsals. Next Episode Next week, we turn to documentation — not as paperwork, but as narrative. Because inspectors don’t just watch what you do. They read what you claim you do.

33 мин.
9 ФЕВР.

Inspectors are coming! Inspectors are coming!

Episode: The Inspection Is Coming: Now What? Release Date: February 9, 2026 When inspectors are on the calendar, anxiety rises fast — but inspections aren’t really about last-minute fixes or perfect binders. In this episode, Dr. Chris Zahner and Dr. Aakash reframe inspections for what they actually are: a stress test of laboratory systems, leadership, and documentation alignment. With rising Medicare scrutiny, new administrative requirements, and advance inspection notice now possible in many settings, this episode sets the foundation for how labs should think about inspection readiness in 2026. This Week’s Highlights Medicare Part B Lab Spending Is Rising $8.4 billion in 2024 lab spending, up 5% year over year43% of all Part B lab dollars now concentrated in genetic testingSpending concentration increases oversight, validation expectations, and inspection intensity — especially for high-dollar testingCLIA Goes Fully Paperless (March 1, 2026) No more paper CLIA certificates or fee couponsLabs must manage certificates, payments, and notices electronicallyInspection risk shifts from “lost paperwork” to missed emails and outdated contactsWhat Inspectors Actually Cite Most Often Top CLIA deficiencies are not dramatic failures — they’re system hygiene issues: Storage conditions not clearly defined or monitoredCompetency assessment gapsSOPs not available or not followedExpired or improperly controlled reagentsInspections With Advance Notice (Up to 14 Days) CAP and The Joint Commission now allow advance notice for some scheduled inspectionsComplaint and follow-up inspections remain unannouncedKnowing inspectors are coming reframes the question: what does being ready actually mean?Deep Dive — Inspectors Are Coming: Now What? What inspections are really testing Inspections don’t evaluate how well you panic or how fast you rewrite SOPs. They assess: System stabilityProcess consistencyLeadership accountabilityWhether documentation reflects realityThe Four Inspection “Gravity Wells” Based on CMS deficiency data, inspection findings cluster around: Storage & environmental controlsCompetency systemsSOP availability and adherenceProficiency testing & director oversightWhat the 14-day notice actually changes Standards don’t changeInspector authority doesn’t changeExcuses disappear Advance notice doesn’t fix culture — it exposes whether it already exists.Why good labs still panic OvercorrectionRewriting systems instead of fixing themTreating findings as personal failure rather than feedbackWhat “inspection-ready” really looks like Boring, accurate documentationSystems that work the same on inspection day as any other TuesdayMinor findings treated as signals, not catastrophes

29 мин.
2 ФЕВР.

Conference Conversations

In this episode of LabReflex, we start with a few high-signal highlights from the past week before stepping back to ask a bigger question: Why does the future of laboratory medicine sound so different depending on which conference you attend? From workforce investments to seasonal flu pressure to high-consequence pathogens like Nipah virus, we explore what’s actually happening on the ground — and then unpack how conferences shape (and sometimes distort) the way we talk about it. This Week’s Highlights The Lab Workforce Story Is Splitting Some institutions are investing heavily in laboratory training pipelines, expanding MLS programs and clinical rotations because they believe diagnostics will become even more central to care. At the same time, other health systems are freezing lab hires, shrinking in-house test menus, and outsourcing more work. Flu Activity in the U.S. Remains Elevated Seasonal influenza activity remains elevated and persistent, with both Influenza A and B contributing. Rather than peaking and resolving quickly, flu has lingered this season, continuing to drive sustained testing demand and operational strain in clinical laboratories. Routine pathogens still matter — especially when they don’t behave routinely. Nipah Virus: A Quiet but Serious Watch We take a closer look at Nipah virus, a zoonotic pathogen circulating sporadically in parts of Asia. While outbreaks remain small and localized, Nipah carries a high case fatality rate (often 40–75%), causes severe encephalitis, and has no widely available vaccine or specific antiviral treatment. Conference Conversations With those highlights in mind, we turn to the conference circuit and ask why labs hear such different futures depending on the room they’re in. We discuss what to listen for at major meetings like: CAP (what’s allowed and defensible in practice)USCAP (what’s coming diagnostically)ADLM (what’s scientifically possible)Executive War College (who owns labs and who pays)Conferences don’t predict the future — they reveal incentives, assumptions, and pressure points. Learning how to read those signals matters more than chasing headlines. Why This Episode Matters Laboratory medicine sits at the intersection of science, operations, and economics. Understanding how narratives form — and why they diverge — helps labs make better decisions, ask better questions, and stay grounded in reality. Subscribe & Follow If you enjoy LabReflex, subscribe wherever you get your podcasts and share the episode with colleagues who live in the space between diagnostics, medicine, and systems thinking.

20 мин.
26 ЯНВ.

When Numbers Feel Certain (But Aren’t Enough)

Episode Overview In this episode of LabReflex, we step back from the question of what tests to order and focus instead on what it actually means when a laboratory result comes back with a single number that feels precise, authoritative, and actionable. Preventive cardiology has become very good at measuring risk, but much less consistent at explaining what that risk represents for an individual patient. Using ApoB and Lipoprotein(a) as concrete examples, this episode explores the growing gap between measurement and meaning, and why laboratories are increasingly being asked to help bridge it. Space Medicine and Diagnostic Decision Making We begin with a brief return to a space medicine scenario to frame the central problem of the episode. In extreme environments, clinicians are forced to make high consequence decisions with limited data, no reflex testing, and no easy opportunity for confirmation. Results carry interpretive weight, not just numeric value, and overconfidence can be more dangerous than uncertainty. Preventive cardiology on Earth is increasingly starting to look similar. One number, large downstream decisions, and an implied sense of certainty that biology does not fully support. Take home.When data are limited and the stakes are high, interpretation matters more than precision. Policy and Reimbursement Update. RESULTS Act and PAMA We then move into a brief update on the current status of the RESULTS Act and ongoing Medicare reimbursement instability under PAMA. There have been no material changes this week, but the government did delay PAMA till Jan 2027. While recent hearings and policy discussions continue to reflect broad acknowledgment that the current reimbursement framework is flawed, there are still no firm timelines for reform. The practical takeaway remains uncertainty. This context matters as laboratories face sustained financial pressure while simultaneously being asked to provide more interpretive and cognitive value. Take home.Reimbursement instability persists. There is momentum, but no resolution. Laboratories are being pushed toward higher value interpretation in an environment with fewer financial buffers. Communication Failures in HealthcareBefore moving into the technical discussion, we address a broader systems issue. Confusion around ApoB and Lipoprotein(a) is not primarily an assay problem. It is a communication and expectation problem. These tests are often presented as answers rather than risk descriptors, which leads to misinterpretation by clinicians and patients alike. This sets the stage for the deep dive without duplicating it. Take home.The failure mode here is not turnaround time or assay quality. It is meaning attribution. ApoB and Lipoprotein(a). What the Tests Actually MeasureThe core of the episode is a technical and clinical discussion of ApoB and Lipoprotein(a). We explain what these tests measure at a biological level, how they are performed in the laboratory, and why they correlate strongly with cardiovascular risk without providing diagnostic certainty. ApoB reflects the number of circulating atherogenic particles and serves as a proxy for cumulative arterial exposure. Lipoprotein(a) reflects genetically determined structural risk that is largely fixed over a lifetime. Both are measured using standard immunoassay techniques rather than exotic or experimental technology. The difficulty lies not in measurement, but in interpretation. Key point.These are excellent tests that describe risk, not disease. Interpretation, Discordance, and the Limits of PrecisionWe then explore why discordance between LDL cholesterol and ApoB creates confusion, and why that discordance usually does not change the choice of therapy but does change expectations around durability, monitoring, and uncertainty. ApoB largely determines whether therapy is effective. LDL cholesterol provides context about particle composition and metabolic stability. Precision in measurement does not translate into precision in meaning, particularly at the individual patient level. Key point.Better numbers do not eliminate uncertainty. They expose it. What This Means for LaboratoriesWe close by reframing the laboratory’s evolving role. As medicine produces increasingly precise risk markers, laboratories are being asked to move beyond result generation and into interpretation support. This includes helping clinicians resolve discordant results, guiding confirmation strategies, and explaining what a number can and cannot tell us. Laboratories are not losing relevance. They are losing the illusion that precision alone is sufficient. Looking AheadNext episode, we extend this conversation into the direct to consumer space and examine what happens when patients order these tests themselves. Not for diagnosis, but for reassurance. We will explore how that shift further transfers responsibility onto laboratories and clinicians, and what that means for the future of diagnostic medicine.

25 мин.
19 ЯНВ.

PCR Leaves the Lab: How At-Home Molecular Testing Actually Works

Episode OverviewIn this episode of LabReflex, we examine what it truly takes to move PCR out of the clinical laboratory and into the home. PCR chemistry itself hasn’t fundamentally changed; what’s changed is the system built around it. This episode focuses on the engineering, controls, and design decisions required to make molecular testing work reliably without trained technologists, controlled environments, or traditional lab workflows—and what that shift means for laboratories. Policy & Reimbursement Update — RESULTS Act / PAMAWe begin with a brief update on the recent House subcommittee hearing related to the RESULTS Act and Medicare payment stability. The tone of the hearing was broadly sympathetic to laboratory concerns, with lawmakers openly acknowledging flaws in PAMA data collection and methodology. However, there were no firm timelines or commitments to legislative action. The takeaway remains uncertainty: there is momentum, but no resolution yet. This context matters as labs face ongoing financial pressure at the same time diagnostic testing is becoming more decentralized. House Energy and Commerce Committee - Jan 8th Meeting on RESULTS Act https://energycommerce.house.gov/events/health-subcommittee-legislative-proposals-to-support-patient-access-to-medicare-services Take Home: “The subcommittee was clearly sympathetic to the problem the RESULTS Act is trying to solve, treated the bill as serious and credible, and framed lab reimbursement instability as a real access issue but did not signal imminent passage.” Flu & Emerging Infectious Disease Check-InNext, we review the current flu and emerging infectious disease landscape. There are no major new strain developments or geographic surprises this week, and diagnostic trends remain consistent with seasonal expectations. While continued monitoring is important, there is nothing driving immediate changes in testing strategy. The larger infectious disease story right now is access and turnaround time, not viral novelty. Flu Updates https://www.cdc.gov/fluview/surveillance/2025-week-53.html Take Home: Overall flu activity is very high, but some indicators flattened slightly this week.That leveling is likely influenced by holiday reporting delays, not a true downturn.Hospitalizations and outpatient visits remain elevated, especially in older adults.Influenza A (H3N2) continues to dominate, which historically correlates with more severe seasons.Pediatric deaths increased again this week, signaling ongoing clinical impact. PCR at Home — What Actually Changed, and Why It MattersThe core of the episode is a technical deep dive into how fully at-home PCR works and why it is non-trivial. We start by reviewing the assumptions PCR has always relied on—trained operators, controlled environments, and clean workflows—and why none of those exist in a home setting. From there, we explain how technology replaces people. Topics covered include how pre-analytics become a design problem rather than a policy problem, how integrated sample preparation replaces the molecular bench, and how microfluidic systems move fluids without pipettes or pumps. We discuss why miniaturized thermal cycling enables rapid PCR, how fluorescence-based detection happens internally while results are presented in simple binary terms, and how internal controls and conservative error logic replace technologist judgment. We also explain why it matters that major laboratory organizations are now offering fully at-home PCR tests through their platforms. These labs are not running the assays—the patient runs the test—but their involvement legitimizes the category, integrates results into care pathways, and signals that decentralized molecular testing is now a permanent part of the diagnostic ecosystem. Finally, we reframe what this shift means for laboratories. As PCR no longer lives exclusively inside the lab, the lab’s value moves toward confirmation strategies, resolving discordant results, interpretation, reporting, and stewardship. Labs don’t lose relevance—they lose monopoly over where testing occurs.

29 мин.
12 ЯНВ.

Power Shifts: AI, Joint Ventures & the New Healthcare Order

Episode Overview In this episode of LabReflex, Dr. Chris Zahner covers several key developments shaping clinical laboratories and healthcare in early 2026. The discussion begins with a brief update on the status of the RESULTS Act and what laboratory leaders should be watching next. From there, the episode explores the launch of ChatGPT Health and what expanding use of generative AI could mean for healthcare decision-making. The conversation then turns to recent diagnostic joint ventures and partnerships, before closing with a set of quick housekeeping updates and notable industry headlines. Segment 1: RESULTS Act — Where Things Stand The episode opens with a concise update on the Reforming and Enhancing Sustainable Updates to Laboratory Testing Services (RESULTS) Act. Chris reviews where the legislation currently stands in Congress, why timing matters heading into 2026, and how laboratories should be thinking about reimbursement planning while the bill remains unresolved. Rather than revisiting the full history of PAMA, the focus is on near-term implications and financial preparedness. Key points discussed include the current protection of Medicare laboratory payment rates, the possibility of future reductions under existing law, and the importance of conservative financial planning while legislative outcomes remain uncertain. Segment 2: ChatGPT Health and AI in Healthcare Chris then discusses the launch of ChatGPT Health from OpenAI and places it in the broader context of artificial intelligence in healthcare. The conversation examines what differentiates a health-focused AI deployment from general consumer tools, how patients are already using AI to interpret symptoms and lab results, and why this trend matters for clinicians and laboratories. The focus is not on technical details, but on how AI is increasingly influencing healthcare decisions upstream of testing and care delivery, shaping patient expectations and clinical workflows. Segment 3: Joint Ventures and Diagnostic Partnerships The episode next turns to recent joint ventures and partnerships in diagnostics, including health system collaborations with large laboratory organizations such as Quest Diagnostics. Chris explains why these arrangements differ from traditional outsourcing and what they signal about how health systems are thinking about laboratory operations, scale, and long-term cost management. The discussion highlights how shared-ownership models can affect governance, operational control, and the future role of hospital-based laboratories within larger networks. Segment 4: Housekeeping and Industry Updates The episode concludes with several brief updates on recent hospital closures, service line changes, and other operational developments affecting healthcare systems. Chris discusses why these events matter for laboratory access, specimen flow, and diagnostic continuity, particularly in smaller or rural communities.

17 мин.
22.12.2025

Year in review

LabReflex 2025 Year in Review Practical progress in an uncertain year As 2025 comes to a close, LabReflex takes a step back to reflect on what actually shaped clinical laboratories this year. This episode is not about big promises or dramatic breakthroughs. It is about how labs responded in practical ways to persistent pressure. Rather than solving long standing problems, many organizations focused on setting reasonable goals, stabilizing operations, and making incremental improvements where they could. In many ways, that mindset defined the year. Workforce strain as a permanent condition Staffing challenges did not resolve in 2025. Instead, they became part of the baseline. Labs shifted from short term crisis management to long term mitigation, prioritizing cross training, service triage, and sustainability. The conversation moved away from restoring ideal staffing levels and toward maintaining safe and reliable operations with fewer people. A more grounded view of artificial intelligenceThe AI conversation matured this year. Expectations collided with operational reality. While interest remained high, adoption slowed as labs focused on validation, integration, and return on effort. Where workflows were already well defined, AI showed promise. Where systems were fragmented, it added complexity rather than relief. Financial uncertainty continues to shape behavior Even without immediate reimbursement cuts, unresolved policy questions continued to influence planning and budgets. Many laboratories responded conservatively, delaying investments, tightening utilization, and modeling multiple future scenarios. The uncertainty itself became a driver of decision making. Workflow matters more than hardware A clear lesson from 2025 was that new analyzers do not fix broken systems. Attention increasingly shifted upstream to specimen flow, staffing models, ordering practices, and communication. Measuring turnaround time by phase rather than as a single number helped labs identify where meaningful improvements were actually possible. Growth areas bring new operational demands Molecular diagnostics and pharmacogenomics continued to expand, but with that growth came increased interpretive workload, reporting complexity, and infrastructure requirements. The technical barriers may be lower than they once were, but the operational burden is very real. Public health pressure returns quietly Outbreak response and policy changes reintroduced a level of background pressure that many labs had hoped was behind them. Readiness is no longer episodic. It is an ongoing expectation layered onto already constrained systems. Looking ahead to 2026 The outlook for 2026 is shaped directly by what we saw in 2025. Workforce shortages are unlikely to resolve quickly. Financial pressure remains unsettled. AI will only succeed where workflows are sound. Progress will continue, but it will be measured, deliberate, and practical. This episode is a realistic assessment of where laboratories are today and how they are moving forward. Not with sweeping transformations, but with thoughtful decisions and achievable goals.

24 мин.
15.12.2025

CAP Changes and New Innovations

LabReflex Podcast – Episode Notes Episode Title: Modern Lab Transitions: CAP’s 2025 Overhaul, Reliable AI, and Diagnostics on the Front Line Host: Dr. Chris Zahner and Dr. Aakash Episode Summary This episode examines the major shifts coming to clinical laboratories as CAP releases its most consequential checklist updates in years. Digital pathology, remote review, and self-collected specimens are now positioned as core operational elements rather than edge capabilities, and we break down what laboratories must understand before their next inspection cycle. We then explore a new AI methodology from Johns Hopkins, known as MIGHT, which aims to provide honest, statistically sound performance estimates for diagnostic machine-learning models—a key step toward trustworthy AI in clinical care. Additional discussion highlights emerging diagnostic technologies featured in recent CAP Today coverage, including expanded pharmacogenomics services, next-generation rapid HbA1c testing, and new frontline infectious disease platforms. We close with updates on PAMA policy movement and recent infectious disease alerts, including a rare donor-derived rabies transmission and early-season respiratory activity. Segment 1: CAP’s 2025 Checklist Overhaul Key discussion points: Digital pathology, remote data assessment, and whole slide imaging are now explicitly included under Laboratory General, signaling CAP’s expectation that digital workflows be treated as part of standard laboratory operations.Requirements related to remote review emphasize secure authentication, data encryption, and auditability.CAP has introduced a new Phase II requirement addressing self-collected specimens such as HPV kits, saliva PCR, FIT kits, and dried blood spots.Patient safety appears as a unifying theme across checklists, reinforcing expectations for labeling accuracy, cross-site consistency, and proactive risk assessments.CAP Today highlights LIS interoperability as a growing pain point for laboratories implementing digital pathology and integrated QC systems.Segment 2: Hopkins MIGHT Method for Reliable Diagnostic AI Key discussion points: MIGHT (Multidimensional Informed Generalized Hypothesis Testing) provides statistically valid estimates of sensitivity, specificity, and ROC performance for machine-learning models, even in high-dimensional, low-sample-size clinical datasets.Hopkins researchers evaluated MIGHT on 1,000 patient blood samples (352 cancer, 648 non-cancer), producing approximately 72 percent sensitivity and 98 percent specificity, and comparing 44 feature sets, with aneuploidy-based markers emerging as the strongest predictors.The method focuses on performance stability: using repeated, independent train-test splits, confidence interval calculations, and formal hypothesis testing to prevent overfitting and inflated performance claims.This approach aligns with emerging expectations from CAP for transparent, reproducible AI validation.Segment 3: Innovation Spotlight Key discussion points: Quest’s expanded pharmacogenomic testing service marks a significant shift as PGx becomes more integrated into routine primary care and specialty workflows. Approximately 30 to 40 percent of patients carry clinically actionable PGx variants, supporting broader use.Tosoh’s GR01 HbA1c analyzer received 510(k) clearance and delivers an HPLC-based A1c result in roughly 50 seconds with coefficient of variation ≤1.1 percent and detection of common hemoglobin variants, enabling near-real-time diabetes management.CAP Today also highlights two emerging diagnostic platforms: Qiagen’s QIAstat-Dx Rise, a high-throughput syndromic PCR system capable of 160 tests per day with automated priority handling, and QuickVue Flu + SARS, a CLIA-waived 10-minute antigen test designed for decentralized settings.MeMed BV, an FDA-cleared host-response assay, continues to gain traction for distinguishing bacterial from viral infections in emergency and urgent care environments.Segment 4: PAMA Update Key discussion points: Quest and LabCorp have launched a coordinated lobbying effort for a delay to the 2026 PAMA repricing cycle, joined by rural and independent laboratory groups emphasizing patient access concerns.Congressional staff have indicated openness to a potential delay, though no formal legislation has yet been introduced.If unchanged, PAMA cuts could lower reimbursement for hundreds of high-volume tests by up to 15 percent.Segment 5: Clinical Alerts Key discussion points: CDC’s MMWR describes a donor-derived rabies transmission involving a kidney recovered from a donor in Idaho who had a skunk scratch approximately six weeks prior to death. The kidney recipient, transplanted in Ohio and residing in Michigan, developed rabies about five weeks post-transplant and died. Three corneal graft recipients received post-exposure prophylaxis following graft removal and remained asymptomatic. This was the fourth known donor-derived rabies transmission in the United States since 1978.Early-season respiratory trends show high influenza-like illness activity in Colorado, Louisiana, and New York City, with rising influenza-associated hospitalizations and a doubling of norovirus positivity rates over recent months.Zika activity remains low in the United States, with only a small number of travel-associated cases reported; WHO has elevated travel risk levels in parts of Latin America and the Caribbean, and CDC has narrowed testing guidance for asymptomatic pregnant patients.Key Takeaways CAP’s 2025 checklist updates signal a structural shift toward digital workflows, remote operations, and decentralized specimen collection as standard laboratory practice.Reliable AI in diagnostics requires not just model accuracy but statistically valid and reproducible performance estimates; MIGHT represents a meaningful step in that direction.Diagnostic innovations are converging toward faster turnaround, decentralization, and clinical decision support.PAMA remains a fluid policy environment, but early signs point to potential congressional engagement on delaying reimbursement cuts.Unusual infectious events such as donor-derived rabies underscore the importance of robust donor screening and public health coordination, while respiratory trends suggest increasing demand for rapid diagnostics.

26 мин.

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A conversational podcast about more innovative diagnostics, lab insights, and the future of clinical testing. Hosted by Dr. Christopher Zahner, LabReflex brings expert voices, industry trends, and practical conversations straight from the laboratory bench to your brain.

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Christopher Zahner, MD
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2025 - 2026
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13
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© 2025 Christopher Zahner / LabReflex