Learning With Lowell

Lowell Thompson

The Learning With Lowell show is a series for the every day mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.

  1. 03/18/2025

    How Long Will You Live? The Future of Longevity Testing w Dr. Matthew Dawson of TruDiagnostic 256

    In this episode, we dive deep into the world of longevity science and epigenetic testing with TruDiagnostic . We discuss the accuracy of biological age tests, the ethical and regulatory challenges in the industry, and how personalized interventions could reshape the future of health. Whether you're skeptical or curious, this conversation uncovers what’s real, what’s hype, and what the future holds for longevity research. https://youtu.be/UzTjW9oDTlE https://youtu.be/UzTjW9oDTlELearning with Lowell links Spotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRH RSS: https://www.learningwithlowell.com/feed/podcast/ Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q Website: https://www.learningwithlowell.com Dr. Matthew Dawson and TruDiagnostic links: https://trudiagnostic.com https://www.linkedin.com/in/matthew-dawson-75196040 About TruDiagnostic “TruDiagnostic is a state of the art epigenetic testing company, specializing in Biological Aging, Nutritional Deficiencies, and Cellular Systems Health based on DNA Methylation. We offer testing for clinical practitioners and their patients, and consumers.  TruDiagnostic is dedicated to utilizing validated research and rigorous scientific standards to expand our knowledge and analysis into Epigenetics and Aging.  We also participate in research studies, using our validated Biological Age test (TruAge) to verify claims from interventional products.  Our goal for the future is to continue to develop our DNA Methylation analytical ability until we can successfully identify markers that can be used by physicians to diagnose age-related diseases before they show outward symptoms, and let them begin early interventions. “ Timestamps: 00:00 - Introduction to longevity, health, and lifespan. 00:05 - Guest introduction: Matt's company was featured on the Kardashians. 00:11 - The Kardashians used Matt’s product and featured it on their show. 00:29 - How the Kardashians initially used the product anonymously. 00:47 - The business impact of being featured on their show. 2:24 - Concerns about a deep science company being associated with pop culture. 3:39 - The role of influencers in translating deep tech for the general public. 4:53 - Questions from new customers after the Kardashian episode. 5:38 - Differentiating from inaccurate biological age tests. 6:08 - Issues with market confusion and low-quality alternatives. 7:03 - Strategies to rise above market noise (publications, collaborations). 8:07 - Explanation of True Diagnostic's work. 9:02 - Why early biological age tests were not useful. 9:40 - The breakthrough with Duke’s "Pace of Aging" test. 10:30 - Sensitivity of the test to interventions (pregnancy, stress, COVID). 11:43 - Clinical use cases: testing interventions in real-time. 12:01 - Accuracy of the new tests versus old biological age models. 13:00 - Practical applications of knowing your aging rate. 14:01 - The relationship between aging and disease risk. 15:02 - Why aging is the biggest health risk factor. 15:20 - Rising chronic diseases and lifestyle factors. 16:49 - Microplastics, environmental toxins, and their potential impact. 17:57 - Exercise and cognitive health. 18:59 - The importance of heart health for brain function. 19:54 - Types of exercise and their impact on aging. 22:14 - How AI can optimize personal health recommendations. 23:48 - AI-assisted food recommendations based on genetics. 25:17 - The future of AI-driven precision medicine. 26:49 - How precision medicine can add 20 years to lifespan. 28:16 - The role of genetic and biomarker testing in personalized medicine. 32:00 - The potential for AI-driven medical interventions. 36:07 - Collaborations with top universities (Harvard, Duke, Mayo Clinic). 38:56 - Using AI for predictive health insights. 42:26 - The possibility of a single blood test diagn...

    1h 35m
  2. 03/06/2025

    Can AI Create the Perfect Meal? The Future of Food Tech – Panos Kostopoulos CEO of Proxy Foods 255

    https://youtu.be/ixZ1oiihRR8 AI is revolutionizing the food industry. Faster product development, personalized nutrition, and even predicting taste and texture. Could your next meal be designed by a machine? About Proxy FoodsProxy Foods  |  AI Recipe Formulation  At Proxy Foods, we introduce Food & Beverage (F&B) manufacturers to the era of AI recipe formulation.   Our platform turbocharges the innovation process for your R&D team by combining advanced data analytics and food science insights with a comprehensive and reliable ingredient database for making data-driven decisions.   Recipe formulation is complex. It requires tackling the sensory (taste, texture, aroma, and appearance), nutritional, and cost variables, with agility and precision.   We equip R&D teams with essential tools and proprietary software to amplify their unparalleled creativity, empowering them to innovate and develop the F&B products they envision, leading to impactful outcomes and the discovery of new flavors. Embrace the taste of change. As demand for nutritious and sustainable food increases, our food systems face unprecedented pressure, driving the search for more efficient and ethical solutions that nurture our planet and respect animal welfare. For these solutions to be widely adopted, they must also be delicious and affordable.  This is a complex challenge, but we're here to help make the process easier and more exciting.  Learning with Lowell links Spotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRH RSS: https://www.learningwithlowell.com/feed/podcast/ Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q Website: https://www.learningwithlowell.com Panos Kostopoulos links https://www.linkedin.com/in/panos-kostopulos https://proxyfoods.ai/ Timestamps: 00:00 – Introduction: Guest met at the Future of Protein Conference in Chicago. (future of protein, alternative protein, startup pitching) 00:11 – Guest shares insights from the conference, including startup pitches and enterprise solutions. 00:52 – Guest's startup, Proxy Foods, participated in the startup pitch at the conference. (startup pitch, alternative protein) 01:41 – What happens after pitching? Discussing outcomes: investors, clients, team members. 02:36 – Conferences as a place for validation and networking outside of formal pitches. 03:32 – Importance of post-conference networking for building relationships and business opportunities. 04:47 – Conferences as "successful collisions" – unexpected but valuable connections. 06:04 – Introduction to Proxy Foods: an AI platform for accelerating product development and reformulation. (AI food development, R&D, food innovation) 09:17 – How Proxy Foods helps R&D teams optimize food formulations for nutrition, flavor, and regulatory compliance. 12:07 – The complexity of food formulation: flavor perception, nutritional balance, and consumer expectations. 14:08 – Breakthrough innovation in plant-based food and why many products lack differentiation. (plant-based food, food innovation) 15:48 – Speeding up food product development from months to weeks with AI. (AI in food, product development speed) 17:18 – Regulatory compliance: digitizing food regulations in the U.S. and Europe for faster formulation checks. 19:00 – The future of food innovation: What’s the next major breakthrough in food technology? 21:02 – Can AI make food taste perfect despite cooking inconsistencies? (AI and cooking, food consistency) 23:41 – Preventing food spoilage and recalls: AI’s role in predicting shelf life and safety. (food safety, AI prediction) 26:33 – Can Proxy Foods help startups create new food innovations affordably? Plans for a lighter version of the platform. (food startups, AI for small businesses) 29:43 – Potential future applications of AI for personalized nutrition and dietary optimization. (personalized nutrition,

    55 min
  3. 01/06/2025

    Is Instalab the future of Longevity Testing and Patient care? Adora cheung – Ep. 255

    What if understanding your health was as simple as ordering a blood test from home? This episode dives into how Instalab is reshaping preventative healthcare by providing accessible diagnostics and personalized care plans. Description:Join us as we speak with a Y Combinator alum and founder of Instalab, a HealthTech startup on a mission to revolutionize the way we approach health and longevity. From advanced diagnostics like calcium scans and Dexa scans to personalized health plans, Instalab is transforming lives by catching potential health risks early. Discover the journey of building a healthcare startup, the challenges of navigating insurance, and the innovative ways technology is being used to create affordable and effective healthcare solutions. Whether you're a tech enthusiast, a startup founder, or someone interested in improving their health, this conversation is packed with actionable insights and inspiring stories. Don’t miss this deep dive into the future of healthcare! Like, comment, and subscribe to stay updated on more transformative stories. https://youtu.be/OmEBO3tW_9A LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QWebsite: https://www.learningwithlowell.com adora cheung linkshttps://www.linkedin.com/in/adoracheunghttps://www.adoracheung.com/abouthttps://www.instalab.com/ Timestamps:0:00 Introduction and background at Y Combinator.0:30 Insights from Y Combinator shaping Instalab.1:18 Skills transition and coding focus.2:36 Customer service involvement and learning by doing.3:35 Technology choices like React and adapting to JavaScript.5:16 Building the founding team and involving family.7:12 Instalab’s mission: proactive health testing and treatments.10:10 Customer journey: diagnostics, care plans, and specialists.13:45 Case studies on health interventions and diagnostics.17:45 Accountability in health improvement through testing.20:58 Navigating insurance, affordability, and medication costs.25:00 Advanced health tests and accessibility.27:00 Early days of Instalab: dual-entity structure and funding.30:10 Importance of careful healthcare delivery and trust.35:25 Iterating operations and design in the startup phase.39:38 Budgeting for health and actionable personal care advice.44:00 Life-saving diagnostics and addressing osteoporosis.49:55 Trends in early diagnosis and preventative care.55:35 Scaling Instalab and educating listeners on health budgets.1:00:00 Books on healthcare, infrastructure, and recommendations.1:07:10 Learning about insurance and interacting with systems. longevity #healthtech #ycombinator

    1h 10m
  4. 11/12/2024

    From Facebook to Fashion: Anya Cheng’s AI-Powered Journey to Revenant Men’s Wardrobe – Ep. 254

    In this insightful interview, Anya Chin, founder and CEO of Taelor, shares her journey of creating an AI-driven fashion rental service for men. She discusses her background in tech, including roles at Facebook, eBay, and McDonald's, which influenced her approach to product development and customer engagement. Anya explains how Taelor was founded to solve a common problem for busy professionals who want to look stylish without the hassle of shopping or laundry. She elaborates on the importance of validating hypotheses early on, her approach to MVP (Minimum Viable Product) testing, and the power of combining AI with human stylists. Anya also dives into customer discovery, the challenges of product-market fit, and her unique approach to supplier partnerships. Through anecdotes about resilience and leveraging her past experiences, she offers valuable insights for aspiring entrepreneurs. Taelor — Men’s wardrobe rental with expert styling.✨.png 30% off first month with code: Lowell30. using link: https://taelor.style/pages/membership?utm_source=podcast&utm_medium=podman&utm_campaign=lowell Give the gift of time and confidence!Taelor Gift Card: https://taelor.style/products/menswear-rental-gift-card?utm_source=podcast&utm_medium=podman&utm_campaign=lowell🎁.png 10% off gift card with code: LowellGift10 LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QKick: https://kick.com/learninglowellTwitch: https://www.twitch.tv/learninglowellWebsite: https://www.learningwithlowell.com Anya Cheng links:https://www.linkedin.com/in/anyacheng/https://taelor.style/ Timestamps:0:00 - Introduction0:13 - Anya's Background1:06 - Personal Connection to Taelor's Concept1:40 - Starting Taelor: Initial Hypotheses and Validation2:36 - Validating Demand Through MVP4:07 - Manual Approach to Early Product Development5:00 - Defining MVP and Hypotheses5:34 - Developing Customer Understanding Through Quiz and Feedback7:02 - Human vs. AI Styling and Customer Feedback8:05 - Market Segmentation and Customer Targeting9:17 - The Value of AI Stylists and Renting Over Buying10:21 - Customer Interview Techniques11:56 - Product Market Fit and Customer Retention13:42 - Avoiding Pitfalls: Knowing When to Pivot15:57 - Defining True Product Market Fit17:03 - Evolving Audience and Business Model19:05 - Supplier Relationships and Data Monetization21:31 - Marketplace Ecosystem Model23:46 - Building a Brand and Expanding Supplier Partnerships27:06 - Learning and Staying Informed28:21 - Teaching as a Form of Learning31:16 - Importance of Helping Others in Networking34:10 - Networking at Conferences36:12 - Focus Areas for Taelor in Late 2024 and 202539:07 - Building Confidence for Customers41:47 - Applying Past Experiences in Product Development44:02 - Recommended Books and Learning Resources45:47 - AI Trends and Future Directions47:03 - Getting Media Coverage50:10 - Incremental Progress and Persistence51:01 - Favorite Chicago Restaurants52:09 - Call to Action: How Listeners Can Help Taelor54:35 - Closing Remarks aistartup #menfashion #ai

    55 min
  5. 08/13/2024

    Dr. Olivia Lesslar and Dr. Alexander Layendecker: Space Sex, Longevity, & Brain Injuries with – 253

    In this episode of the Learning with Lowell podcast, host Lowell Thompson welcomes Olivia Lesslar and Alexander Layendecker, two experts in the fields of space life sciences and medicine. The discussion delves into the challenges and innovations surrounding human health and reproduction in space. Topics covered include the impacts of microgravity and radiation on human physiology, the intersection of longevity research with space sciences, and the potential for space research to address earthly health issues. The conversation also explores cutting-edge advancements in quantum medicine, neuroplasticity, and the role of light and electromagnetism in healing. The episode provides insights into the upcoming symposium on human reproduction in space and emphasizes the importance of holistic approaches to health, both on Earth and in space. PODCAST INFO:The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com Dr. Olivia Lesslar and Dr.Alexander Layendecker linkshttps://www.linkedin.com/in/drolivialesslar/https://www.drolivialesslar.com/https://www.asri.space/ Timestamps00:00 - Introduction and Importance of Subscribing01:00 - Guest Introductions: Olivia and Alex's Backgrounds04:00 - Discussion on Space Life Sciences and Research07:30 - Challenges and Risks of Human Reproduction in Space12:00 - Health Impacts of Microgravity and Radiation16:00 - Overlapping Research in Longevity and Space Sciences19:30 - Environmental Factors and Human Health24:00 - Importance of Sleep and Brain Health28:00 - The Effects of Breathing and Stress on Health33:00 - Rehabilitation and Healing Strategies for Brain Injuries38:00 - Advancements in Quantum Medicine and Mitochondrial Health43:30 - The Intersection of Light, Electromagnetism, and Healing49:00 - Legacy Sciences and Azri's Mission53:00 - Future of Space Travel and Human Adaptation57:00 - The Psychological and Social Impact of Space Exploration1:02:00 - Addressing Challenges on Earth Through Space Research1:07:30 - Symposium on Human Reproduction in Space1:11:00 - Impact of Space Research on Earthly Issues1:15:00 - Audience Engagement and Future Directions1:18:00 - Questions about Human Behavior and Health in Space1:22:00 - Intersection of Historical Perspectives and Modern Issues1:27:00 - Personal Insights and Anecdotes from Olivia and Alex1:32:00 - Final Thoughts on Space Exploration and Its Benefits1:36:00 - Historical and Personal Reflections on War and Conflict1:40:00 - Reflections on Public Perceptions and Social Media's Impact1:44:00 - Ethical Considerations and the Role of Science in Society1:48:00 - Future Projects and Research Initiatives1:52:00 - Engaging the Public and Building Awareness longevity #reproduction #space

    1h 54m
  6. 08/13/2024

    Mike Petegorsky: Mindbloom’s At-home Ketamine Therapy, MDMA vs FDA Issues, & Taking Ketamine – 252

    Mindbloom is a mental health and wellbeing company helping people achieve personal and clinical breakthroughs with at-home, clinician-prescribed psychedelic therapies. Mike Petegorsky is the Chief Strategy Officer at Mindbloom. Michael was previously a commercial and IP case litigator for Fortune 50 companies at NYC firms Akin Gump and Ropes & Gray. Michael was named One to Watch by Best Lawyers in America and is a charter member of TechGC, an invitation-only community for General Counsels of venture backed high growth startups. He received his J.D. from Fordham University School of Law and B.A. from the University of Pennsylvania. Other psychedelics episodes to check outBrom Rector - psychedelic investor: https://youtu.be/XX5QlHbDHBsDr. Jacob Aday - psychedelic researcher: https://youtu.be/8JUS92TvGroDr. Joseph Zamaria - board-certified psychologist : https://youtu.be/JjpZ2Eqw2XUSam Believe - ayahuasca psychedelic retreat: https://youtu.be/1JOmSVheiBwDr. Parker Kelley - psychoimmunology, biomedical sciences, psychedelics: https://youtu.be/1M-tN4cnM3Y PODCAST INFO:The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com Mike Petegorsky linkshttps://www.mindbloom.com/https://www.linkedin.com/in/michael-petegorsky-41059614/ Timestamps00:00 Start / introducing Mike Petegorsky and mindbloom leading business offering at-home ketamine therapy01:32 Mike Petegorsky’s journey from IP fortune 50 lawyer to Mindbloom04:30 USA SSRI capital of the world05:30 Mental health professionals need better resources to help06:30 Ketamine vs SSRIs vs just therapy09:30 Withdrawal and ketamine10:24 why Mike Petegorsky used ketamine / Mindbloom’s ketamine protocol13:00 Mike Petegorsky’s first ketamine experience17:40 Psychedelics and ketamine therapy / Mike Petegorsky’s core belief19:10 Meditation giving more anxiety vs after ketamine therapy20:25 sam harris meditation app21:30 Lowell’s experience in the hospital23:30 “Bad” experiences with Ketamine and provider fails / what ketamine feels like27:30 Mindbloom therapy explained28:30 Mike Petegorsky’s IP background applied Mindbloom / Patents in psychedelics33:30 Mindbloom developing IP38:15 Mindbloom ketamine therapy cost40:50 Mindbloom telemedicine benefits / anxiety, PTSD, convenience42:20 VFW partnership to help veterans with anxiety, depression, and PTSD45:00 Mike Petegorsky path to Congress / telemedicine / psychedelics50:41 Mike Petegorsky’s process to get Congress to take his meetings53:30 Mindbloom Not outsourcing core competency / how to high level network57:20 Psychedelics vs other therapies to help people59:24 Cold Emails / Cold out reach / People want to help01:02:30 Respecting people’s time01:03:45 Mindbloom & 15 Commitments of Conscious Leadership01:06:18 MDMA’s FDA federal approval drama explained01:08:50 FDA committee wrong on all counts / Effectiveness and safety01:16:22 Placebo vs control group01:16:50 Why Mike Petegorsky believes the FDA is going to approve anyway01:18:30 People need MDMA now / safety explained01:26:40 Bias in the FDA committee against psychedelics01:30:40 Potential for bias and undue influence01:32:43 Why FDA will over rule FDA committee01:33:35 Mindbloom future psychedelic therapies / Dr. Joe Zamaria question01:36:18 Mindbloom focus vs doing too much at once01:38:00 MDMA truck / buses and law response01:40:20 “If you will it,

    1h 41m
  7. 08/13/2024

    Kim Rahir: From Blind & Wheelchair Bound to Successful Olympic Weight Lifting & Powerlifting – 251

    Kim takes you to the next level of health and performance without the standard prescription of hours of cardio or chicken and broccoli.With laser focus on what has been proven to work for improved performance, sleep, cognitive function, metabolic health and stress levels, you will get maximum results with minimum effort. Work smarter, not harder to make your body look and perform the way you intend it to.The Fabulous in 15 approach is a minimalist protocol that takes you from stressed and tired to vibrant and energetic in the shortest possible amount of time. Check out these other great views as well:Interview with Aubrey De Grey: https://youtu.be/DHvoPlcWwg4Interview with George Church: https://youtu.be/yNplpykf0B4Interview with Lisa Fabiny-Kiser: https://youtu.be/bE5jEGE5-OMInterview with Matt Kaeberlein: https://youtu.be/9QJ_ak3a05QInterview with Nir Barzilai : https://youtu.be/LuOAShcjOt0Interview with Michael Levin : https://youtu.be/5XvDdbYzwf8. PODCAST INFO:The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com Kim rahir linkshttps://kimrahir.com/https://www.linkedin.com/in/kim-rahir/?originalSubdomain=eshttps://www.instagram.com/kim.rahir/?hl=en Timestamps / chapters00:00 Start00:05 Kim Rahir00:50 Accomplishments after MS diagnosis / Olympic weight lifting02:04 Olympic weight lifting03:00 Deadlift04:30 Powerlifting07:55 Mike Tyson, Adversity and training10:10 Rejuvenating after training13:00 Getting through lack of motivations / 5 minute rule16:55 Only 5 minutes19:15 Lifelong learning24:20 Wheelchair to power lifting29:40 MS32:55 202434:55 Dream number36:55 Meditation / mindfulness39:00 Learn mediation / headspace41:45 Strength training43:40 Weeks until getting better45:55 Train to failure48:00 Health and energy focused49:30 Time intensity52:40 Diet / food!54:55 Family dinners and not over eating57:55 Celebrities / interesting meals01:01:45 Community01:05:10 Saying what you want01:08:55 how to get family on board01:11:30 Women vs men advantages and disadvantages01:13:10 Adversity01:14:30 Self Advocacy / MS diagnosis01:22:00 Post having kids01:23:55 One thing you can do right now01:24:55 Her Clients01:25:40 Thank you for all the fish weightlifting #multiplesclerosis #olympicweightlifting

    1h 26m
  8. 08/13/2024

    Dr. David Katz: Lifespan Clock, Bodies Destroying Themselves, & Evolution Selecting for Aging – 250

    “My long-term goal is to model the pathways involved in human aging in order to develop therapeutic interventions. I organize an annual aging conference in the Midwestern United States with the dual goal of promoting the aging as an adaptation theory and promoting the aging as a disease mindset. The conference website is curing-aging.com.” Check out these other great views as well:Interview with Aubrey De Grey: https://youtu.be/DHvoPlcWwg4Interview with George Church: https://youtu.be/yNplpykf0B4Interview with Lisa Fabiny-Kiser: https://youtu.be/bE5jEGE5-OMInterview with Matt Kaeberlein: https://youtu.be/9QJ_ak3a05QInterview with Nir Barzilai : https://youtu.be/LuOAShcjOt0Interview with Michael Levin : https://youtu.be/5XvDdbYzwf8. PODCAST INFO:The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com David Katz linkshttps://www.linkedin.com/in/davidwarrenkatz/https://www.youtube.com/watch?v=zhbOo_INMwg&t=65s&ab_channel=CuringAginghttps://www.curing-aging.com/ Timestamps00:00 start00:20 Programed aging hypothesis explained01:20 Michael Levin / bioelectricity02:15 Telomerase / concerns around copies of copies04:15 Ability for immortality in animals04:44 Immortal jellyfish06:02 Butterfly brains06:40 Programmed aging in practice for therapies07:16 FDA aging as a disease08:33 Curing aging objectionable09:15 We need to work against our bodies10:18 Fasting / Michael Rae / Caloric restriction11:55 Highly against Richard Dawkins selfish gene and ideas around evolution13:20 Start of slides13:50 Why do we age / David’s argument18:20 Different types of aging23:20 Induce damage to test hypothesis25:10 David St Clair work26:20 Evolution has consistently selected for aging29:20 Aging and cancer30:00 exponential population growth31:00 Evolution as an ecological thing32:00 Animals getting bigger and smaller on small island / evolution as multivariable equation35:11 Mole Rats and rats36:25 people who get castrated live longer37:22 Bryan Johnson / interfering with body38:00 Testosterone / women live longer39:22 Mechanism of the body working against itself40:15 Easy interventions / keeping track of time for puberty, death, etc44:30 Squirrels having a year long internal clock46:00 Uniform life events / aging clock / evidence that convinces people50:50 ATF4 Pathway / muscle mass52:00 Not even trying to make therapies ATF454:40 Developing therapies against the body55:30 VCs at conference56:10 Exploring this hypothesis58:40 Tricking body to “think” it’s younger59:10 Aubrey De Grey like hallmarks of aging clock1:00:00 Epigenetic clocks / biologic clocks01:01:30 Disrupting dreams / sleep01:02:50 Sleep affecting aging01:04:08 People who stop sleeping die within a number of weeks01:04:40 Does the biological clock have state and turning it back01:10:20 Steel man argument against the Programed aging hypothesis01:10:55 A good case for the clock / time of day, year, and stage of year01:13:00 Dolphins and sleep01:13:30 Target therapy with this theory01:15:40 Children's hospital01:16:05 Kids better able to fight off cancer / medicine divided01:17:11 PhD Tensor decomposition presentation / fundamental relationship of matrices01:18:40 implications and pushback for the tensor decomposition01:19:30 What are the trade offs / stop measuring algorithms based off complexity01:21:18 Real life example / chromosomes01:24:30 SENS and the human genome li...

    1h 34m
4.6
out of 5
30 Ratings

About

The Learning With Lowell show is a series for the every day mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.