Let's talk e-cigarettes

Oxford University

Since coming on the market over a decade ago, e-cigarettes have divided opinion. A team of Oxford researchers are searching for new e-cigarette studies every month. In this podcast series, Dr Jamie Hartmann-Boyce and Dr Nicola Lindson talk about what has been found, and how this changes what we know about e-cigarettes. This podcast is made possible through generous funding from Cancer Research UK. Art work by Olivia Barratier. Produced by Dr Ailsa Butler.

  1. hace 2 días

    Jessica Yingst, Let's talk e-cigarettes, June 2026

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Jessica Yingst, Penn State Center for Research on Tobacco and Health, USA. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Dr Jessica Yingst. Dr Jessica Yingst is a member of the Penn State Center for Research on Tobacco and Health and is the co-director of the Career Enhancement Core with the Penn State Tobacco Center of Regulatory Science otherwise known as a TCORS. Jessica Yingst is a public health researcher focused on understanding methods to reduce harms associated with tobacco use. In the June podcast Jessica Yingst shares the findings of their randomised clinical trial comparing standardized research e-cigarette (SREC) with 5% nicotine or 0%. Their study explored toxicant exposures after switching from cigarettes to a pod-based electronic cigarette. They wanted to determine the short-term effects of switching from cigarettes to a pod-based 5% nicotine e-cigarette, compared with a 0% nicotine e-cigarette. Their study found that participants who switched from cigarettes to a 5% nicotine SREC experienced reduced exposure to several tobacco-related toxicants and higher rates of cigarette abstinence than those who switched to a 0% nicotine SREC. Their findings suggest that e-cigarettes delivering nicotine at levels comparable to conventional cigarettes may play an important role in reducing exposure to harmful smoking-related toxicants while supporting complete smoking cessation. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Our searches for the EC for smoking cessation review carried out on 1st June 2026 found: 3 new ongoing studies (NCT07039292, NCT07598136, NCT07199517) and 3 linked reports (10.1001/jamanetworkopen.2026.13292 (discussed in this podcast), 10.18332/tid/218987, 10.1111/add.70421). Our search for our interventions for quitting vaping review carried out on 1st June 2026 found: 5 new ongoing studies (ACTRN12626000548336, NCT05037656, NCT07593742, 10.1186/s12889-026-27567-y, 10.1038/s41598-026-45720-w). For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full For more information on the full Cochrane review of Interventions for quitting vaping published in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full

    26 min
  2. 28 may

    Let's talk e-cigarettes, May 2026

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Jonathan Livingstone-Banks, University of Oxford, UK. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Dr Jonathan Livingstone-Banks lecturer & senior researcher in evidence-based healthcare in the Nuffield Department of Primary Care Health Sciences, University of Oxford. Dr Livingstone-Banks is part of the Tobacco Addiction Group within the Centre for Evidence-Based Medicine. He carries out research in the field of tobacco control and evidence synthesis and is involved in many Cochrane Reviews on tobacco control topics. Dr Livingstone-Banks is also a philosopher interested in the philosophy of evidence-based healthcare. In the May podcast Jonathan Livingstone-Banks discusses the findings of his overview of systematic reviews on the impacts of e-cigarette flavours. This is set against the backdrop of the first market authorisation of non-menthol, non-tobacco flavoured e-cigarettes in the US. The overview of reviews includes 32 reviews, 11 of which are higher quality and 21 of lower quality, and covers 1967 primary studies. Jonathan Livingstone-Banks outlines how e-cigarette flavours have the potential to impact a range of outcomes including e-cigarette and combustible cigarette use, safety profile, appeal, and perceptions of harm and how these may differ across different population groups. Overall, he considers that the data on flavours is limited and the impacts of e-cigarette flavours on e-cigarette and cigarette use are inconclusive. Further studies are needed to shed more light on this topic. Reference for the overview of systematic reviews discussed in this podcast: Livingstone-Banks J, Travis N, Conde M, Chen Y(C), Zi P, Jarman H, et al. The impacts of e-cigarette flavours: An overview of systematic reviews. Addiction. 2025;120(7):1327-1344. https://doi.org/10.1111/add.70017 This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Our searches for the EC for smoking cessation review carried out on 1st May 2026 found: 1 linked report (10.1186/s13063-026-09622-6). Our search for our interventions for quitting vaping review carried out on 1st May 2026 found: 1 new study (10.1016/j.acap.2026.103328) and 1 ongoing study (ACTRN12626000336381). For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full For more information on the full Cochrane review of Interventions for quitting vaping published in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full

    19 min
  3. 27 abr

    Let's talk e-cigarettes, April 2026

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Dr Xinxin Yang, University of Oxford, UK. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Dr Xinxin Yang. Dr Xinxin Yang is a qualitative researcher in the Department of Primary Care Health Sciences, University of Oxford. She is part of the Tobacco Addiction Group within the Centre for Evidence-Based Medicine. Dr Xinxin Yang is a Conversation Analyst on the TRIDENT (Tobacco RIsk reDuction with E-cigarette Nicotine Replacement Therapy) project, which aims to develop and deliver tailored smoking harm reduction interventions for people with serious mental illness in routine mental healthcare. In the April 2026 podcast Xinxin talks to Nicola Lindson about conversation analysis work on the MaSC study (Management of Smoking in Primary Care). In the MaSC study usual care was compared to brief advice and an offer to try an e-cigarette. The numbers of participants who reduced and quit smoking were measured at follow-up. She describes how the findings from MaSC will be used to design a communication guide that will be used to train the clinical professionals to deliver the offer of an e-cigarette for the TRIDENT trial. In TRIDENT consultations between the clinicians delivering the offer of e-cigarettes to patients will then be recorded and analysed with conversation analysis. Xinxin explains how this will provide some of the first real-world evidence on how to deliver smoking reduction intervention effectively for people with serious mental illness. This could prove to be valuable for clinicians and also for the service users. The findings may feed into a larger scale trial to be conducted across the UK. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Our searches for the EC for smoking cessation review carried out on 1st April 2026 found: 3 linked reports (10.1158/1940-6207.CAPR-25-0244, 10.1016/j.addbeh.2026.108672, 10.64898/2026.03.18.26348637). Our search for our interventions for quitting vaping review carried out on 1st April 2026 found: 1 linked report (10.2196/79667). For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full For more information on the full Cochrane review of Interventions for quitting vaping published in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full

    21 min
  4. 30 mar

    Let's talk e-cigarettes, March 2026

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Dr Pamela Ling, University of California San Francisco. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Dr Pamela Ling, Professor of Medicine and Director of the Center for Tobacco Control Research and Education at the University of California San Francisco. In the March 2026 podcast Pamela Ling talks to Nicola Lindson about her newly published study that recruited approximately 500 13 to 21 year olds to test whether Instagram support groups can help people to quit vaping compared to referral to a quitline. This randomized clinical study was funded by the UCSF Helen Diller Comprehensive Cancer Center and the Tobacco-Related Diseases Research Program and is published in the American Journal of Preventive Medicine. The intervention, Instagram direct message support groups, was delivered over 5 weeks and involved motivational interviewing, social support, skill building, and group quit attempts. The control group was referral to Quitline in California, the resources for this included telephone, online, texting or mobile app. Pam Ling’s study found that social media support groups were acceptable to adolescents and young adults and improved abstinence rates on average over 6 months compared to quitline referral. Pam Ling discusses the finding that social media platforms may be a useful way to deliver social supports for nicotine vaping cessation that is accessible and utilised by young people. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Our searches for the EC for smoking cessation review carried out on 1st March 2026 found: 1 new (Papadosifaki et al, Archives Hellenic Medicine 2026;43(2):205-211) and 3 linked reports (10.1093/ntr/ntag038; 10.1093/sleep/zsag028; 10.1017/S1463423626100942). Our search for our interventions for quitting vaping review carried out on 1st March 2026 found: 1 new (discussed in this podcast 10.1016/j.amepre.2026.108314), 5 linked reports (10.1016/j.acap.2025.103181, 10.1038/s41386-024-02012-z, 10.1186/s40814-026-01782-1, 10.1016/S2468-2667(26)00021-6, 10.1016/S2468-2667(26)00020-4) and 2 new ongoing (ACTRN12626000031369 2026, NCT07392125 2026). For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full For more information on the full Cochrane review of Interventions for quitting vaping published in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full This podcast is supported by Cancer Research UK.

    22 min
  5. 25 feb

    Let's talk e-cigarettes, February 2026

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Jodi Gilman, Department of Psychiatry at Harvard Medical School and Massachusetts General Hospital. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Dr Jodi Gilman, Associate Professor of Psychology in the Department of Psychiatry at Harvard Medical School and Massachusetts General Hospital. In the February 2026 podcast Jodi Gilman talks about their secondary analysis of a randomised clinical trial looking at cannabis use and nicotine vaping cessation outcomes among adolescents and young adults. Participants were 16 to 25 and reported vaping nicotine regularly and did not smoke tobacco. The full study assessed the efficacy of varenicline for nicotine vaping cessation. For more detail on the parent trial listen to the interview with Eden Evins in the April 2025 podcast. Jodi Gilman discusses the finding that, among adolescents and young adults attempting to reduce or stop nicotine vaping, baseline cannabis use was not associated with nicotine vaping abstinence. Varenicline was helpful for nicotine vaping cessation regardless of cannabis use. This finding indicates that co-use of cannabis may not be a barrier to successful nicotine vaping cessation treatment. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Reference for the paper by Gilman discussed in this podcast, January 2026 search: 10.1001/jamanetworkopen.2025.47799. Parent study by Evins: 10.1001/jama.2025.3810. Our searches for the EC for smoking cessation review carried out on 1st February 2026 found: 4 linked reports (10.1016/j.cct.2026.108215; 1; 0.1111/add.70294; 10.1007/s11606-024-08797-5; 10.1016/j.lana.2025.101351) Our search for our interventions for quitting vaping review carried out on 1st February 2026 found: 1 new study (10.1111/jrh.70109) and 2 linked reports (10.1002/adaw.34496; 10.1007/s11606-024-08797-5). For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full For more information on the full Cochrane review of Interventions for quitting vaping published in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full This podcast is supported by Cancer Research UK.

    14 min
  6. 29 ene

    Let's talk e-cigarettes, January 2026

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and discuss the living systematic review process. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research outline. Nicola and Jamie describe what a living review is and discuss the steps involved in carrying out a living systematic review, from screening and extraction to data analysis and dissemination. They outline how the methods differ from traditional systematic reviews. They highlight the value of the living review process for the fast-moving topic of vape research. This approach means that the author team are constantly up-to-date with the literature and able to input into policy and to respond to press or research queries. They share they full details of the monthly searches, to access the spreadsheet click on 'monthly search finding' near the top of the project webpage (https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1). This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Our searches for the EC for smoking cessation review carried out on 1st December 2025 found 3 linked reports (10.3310/GJLD2428; 10.1093/ntr/ntaf250; Efthimiou 2025, Swiss Medical Weekly 2025;155(Supplement 285):111s). The search on 1st January found 1 new ongoing study (NCT07274475) and 5 linked reports (10.1037/pha0000814; 10.3390/ijerph22121819; 10.1093/ntr/ntaf240; 10.1007/s00213-025-06868-x; 10.1111/jsr.14291). Our search for our interventions for quitting vaping review carried out 1st December 2025 found: 2 new ongoing (ChiCTR2500111503; NCT07223879) and 2 linked (10.1080/14656566.2025.2594050; 10.1186/s13011-025-00679-10. The search on 1st January 2026 found 1 new ongoing (NCT06644664) and 2 linked (10.1001/jamanetworkopen.2025.47799; 10.1093/pch/pxaf116.058). For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full For more information on the full Cochrane review of Interventions for quitting vaping published in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full This podcast is supported by Cancer Research UK.

    21 min
  7. 01/12/2025

    Let's talk e-cigarettes, November 2025

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Elly Leavens, University of Kansas Medical Center, USA. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Dr. Elly Leavens, Assistant Professor in the Department of Population Health at the University of Kansas Medical Center. In the November 2025 podcast Elly Leavens talks about her recent pilot trial published in Frontiers in Public Health, called 'E-cigarette puff topography instruction to enhance switching among COPD patients who smoke'. This pilot study was supported by funds from the Cancer Prevention and Control Program within the University of Kansas Cancer Center, as well as by the National Cancer Institute. The 46 participants who smoked and had chronic obstructive pulmonary disease (COPD) completed a 12-week e-cigarette switching trial in which they were randomized to brief advice or low intensity, or high-intensity puffing topography training. Elly Leavens and colleagues found that e-cigarettes had potential to minimize harm in COPD patients who smoke, but that, puff topography training did not change switch success or reduction in cigarette smoking as compared to the brief advice to switch. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Our searches for the EC for smoking cessation review carried out on 1st November 2025 found: 1 new study (10.1037/adb0001100); 2 ongoing new studies (NCT07172438; NCT07202039); and 1 linked report reported in this podcast (10.3389/fpubh.2025.1664400). Our search for our interventions for quitting vaping review carried out 1st November 2025 found: 1 new ongoing study (NCT07207850). For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full For more information on the full Cochrane review of Interventions for quitting vaping published in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full This podcast is supported by Cancer Research UK.

    22 min
  8. 27/10/2025

    Let’s talk e-cigarettes, October 2025, episode 46

    Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Justin Strickland, Johns Hopkins University School of Medicine. Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Justin Strickland, Associate Professor of Psychiatry and Behavioral Sciences, Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine. In the October 2025 podcast Justin Strickland talks about his work on e-cigarette withdrawal syndrome presented at the 13th Annual Vermont Center on Behavior and Health Conference, held in Vermont, USA. Justin is a behavioural pharmacologist working with substance use and substance use disorder. His research applies behavioural economic methods to evaluate choice and decision-making mechanisms that may underlie substance use and identify targets for their reduction. Justin begins by describing behavioral economics and how our environment and context shape the decisions we make, for example, how the cost of goods can influence patterns of consumption. As a relatively new class of products less is known about e-cigarette withdrawal than tobacco withdrawal syndrome. Justin describes his ongoing study of e-cigarette withdrawal syndrome among people who have exclusively used e-cigarettes. Participants stay in a residential unit for one week, where their behaviour, physiology and other measures, including their nicotine clearance, are measured. Preliminary findings indicate that participants do experience withdrawal to e-cigarettes, for example cravings that reduce over time. Looking to the future he calls for longer-term trials to observe behaviour and to explore predictors of complete cessation. Such research could inform the development of more effective behavioral interventions or pharmacological treatments to support individuals experiencing e-cigarette withdrawal. This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches. Our searches for the EC for smoking cessation review carried out on 1st October 2025 found: 1 new study (10.18332/852498tivblr); 2 ongoing new studies (ISRCTN12504090, 10.1177/29768357251337050); and 4 linked reports (10.1016/j.ypmed.2025.108414, 10.1037/pha0000803, 10.1093/ntr/ntaf200, 10.1101/2024.06.21.24309282). Our search for our interventions for quitting vaping review carried out 1st October 2025 found: 1 new ongoing study (10.3389/fpubh.2025.1618341). For further details see our webpage under 'Monthly search findings': https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1 For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub9/full For more information on the full Cochrane review of Interventions for quitting vaping published in January 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub2/full This podcast is supported by Cancer Research UK.

    17 min

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Since coming on the market over a decade ago, e-cigarettes have divided opinion. A team of Oxford researchers are searching for new e-cigarette studies every month. In this podcast series, Dr Jamie Hartmann-Boyce and Dr Nicola Lindson talk about what has been found, and how this changes what we know about e-cigarettes. This podcast is made possible through generous funding from Cancer Research UK. Art work by Olivia Barratier. Produced by Dr Ailsa Butler.

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