Life Sciences Today

Danny Lieberman and John Lynn
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The Life Sciences Today podcast by Healthcare IT Today brings you strategic conversations with life science founders. Hosts Danny Lieberman and John Lynn and their guests reveal the patterns behind sustainable competitive advantages. Subscribe to the Clear Thinking newsletter by Danny Lieberman for deeper pattern analysis.

  1. 4d ago

    Breaking Clinical Data Chaos

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Raj Indupuri, Co-Founder and CEO at eClinical Solutions. Why is clinical development still run like a sequence of handoffs instead of a continuous learning system? In this episode, I talk with Indupuri about the industry’s biggest anti-pattern: milestone-based, sequential trials. We discuss clinical data chaos, AI in regulated environments, the real moat behind trusted execution, and how sponsors are starting to treat clinical data as core IP. We also dig into switching costs, CRO channel conflict, and what Indupuri says eClinical will deliver for customers over the next 12 months: faster cycle times, less manual work, and more agile decision-making. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: What’s the biggest anti-pattern in the industry? Tell me about your personal journey. How do you create value? How do you capture value? You work with sponsors and CROs – how do you handle channel conflict? What is your moat? What does a greenfield competitor building this today get right that you can’t? What are three things you are going to do for your customers in the next twelve months? Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  2. Jul 17

    Using AI to Reduce Biostatistical Analysis Readouts

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Kyle McBride, VP, AI Innovation at Veristat. We talked about InStat, the clinical research industry’s first zero-code, fully automated biostatistics solution, reducing manual effort to speed time to approval with every output backed by validated statistical engines and expert biostatistician review. It delivers submission-ready tables, listings, and figures (TLF) in five days or less*, rather than the four to six weeks that sponsors typically wait after database lock, while maintaining the highest-quality data. McBride has taken a first-principles approach to designing the software components to fully automate biostatistics in clinical trials using AI. We spoke about the gap between AI demos and AI that actually ships in regulated environments, the economics of CRO delivery in an AI-native world, and the operational realities of running an AI transformation inside a 20-year-old CRO. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell me about your journey. How did you end up doing what you do now? What’s the value creation in AI-augmented biostatistics? How do you capture value? What is your moat? Are you still using SDTM? What are three things you want to do for your customers in 2026? What’s the biggest anti-pattern in the industry? Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  3. Jul 10

    Why the Industry You've Never Heard Of Is About to Change Hands

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Rachel Timberlake, Director of Business Development, Bend Bioscience. Contract manufacturing is a ~$275B global industry most people outside pharma have never heard of. Every drug you’ve ever taken and most of the medical devices you’ve ever used were made, at least in part, by a CDMO — a Contract Development and Manufacturing Organization — that your doctor, your pharmacist, and usually the drug company’s own marketing team will never mention. For the last decade, these businesses have been quietly rolled up by private equity, and 2026 is shaping up to be the year the ZIRP-era platforms either exit well, exit badly, or get absorbed into something bigger. Timberlake has spent two decades inside this industry. She started at a small owner-operated CDMO doing — in her words — “chief cook and bottle washer” work and moved through roles of increasing scale into national sales leadership. Timberlake is one of the few people who can explain this industry in plain language — she has lived every altitude of it, from small-shop BD to national sales leadership inside a large platform, and she is now choosing what comes next. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: What is a CDMO? What does a sponsor actually buy, and why doesn’t every drug or device company just build its own factory? Chief cook and bottle washer to national sales — what did a small CDMO look like when you started, and what did business development actually mean back then? When a biotech CEO calls a CDMO for the first time, what does the first ninety days actually look like — and where does it most often go sideways? Onshoring is the tailwind everyone is talking about — BIOSECURE, tariffs, GLP-1 capacity. What are you actually seeing in the RFPs? What should a founder ask a CDMO in diligence that most of them don’t think to ask? What is the biggest anti-pattern you see at the sponsor–CDMO interface? What’s the kind of problem you’d most want to work on next? Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  4. Jul 3

    The Kids Nobody Builds For: Why Pediatrics is the Hardest Problem

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Dr. Darren Klugman, Founder at Alumni Ventures. In this episode, Klugman and I confront the most uncomfortable truth in life sciences — that the financial model gates the science, and the patients who need innovation most (children) are the ones the market systematically ignores. Klugman brings the clinician’s view from the CICU, the quality leader’s view from Johns Hopkins, and the founder’s view from a company he’s building to fix what’s broken in pediatric care. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: You went from Emory undergrad to Drexel master’s to GWU med school to Children’s National to Johns Hopkins CICU director. That’s a very deliberate path into one of the hardest corners of medicine. What was the moment that locked you in — and what does 20 years in pediatric cardiac critical care do to how you see the life sciences industry? You told me that data, stakeholder alignment, adoption, and reimbursement are all tightly intertwined — pull one thread and the whole thing unravels. In your experience running quality and safety programs across institutions, what does it actually look like when a clinical innovation gets all of those things right? What’s the anatomy of a win? How are you thinking about value capture in pediatrics, where the market is structurally small and the patients are the most vulnerable?  If you could move three needles this year — for the kids in your CICU, for the physicians trying to care for them, or for the system that’s supposed to support both — what are they? You said it plainly: the financial model gates the science, and pediatrics pays the price because there’s no big enough TAM. Is that the anti-pattern — or is there something deeper underneath it? And what does the fix actually require? Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  5. Jun 26

    Enriching Psychiatric Evaluations with AI

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Iris Shtein, Co-Founder and CEO at Mentaily. Due to limited resources and social misconceptions, only 44% of US adults are receiving the treatment they need. Patients endure long wait times due to traditional intake processes. Mentaily – a patented AI model – creates diagnostic intelligence with almost perfect accuracy by the DSM gold standard, before the patient’s first engagement with a clinician. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell us about your journey. What does Mentaily do? Who are your customers? What’s your moat? What’s your superpower? What’s the business model? How do you capture value? What is the biggest anti-pattern in your industry today? Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  6. Jun 19

    Military Intelligence Meets Pharma Strategy

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Tony Page, Senior Vice President of Insight Analytics at Within3. Page spent years applying military intelligence doctrine — structured analysis, adversarial thinking, decision superiority — before bringing those frameworks into pharma. As SVP of Insight Analytics at Within3, he’s now helping life science companies move from reactive milestone-chasing to proactive, intelligence-driven launch strategy. In this episode, Page and I unpack why pharma launch teams are flying blind, what “insights management” actually means in practice, and why the companies winning in 2026 are the ones treating competitive intelligence as a strategic pillar — not a reporting function. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: What was the moment you realized that intelligence doctrine could solve something broken in life sciences? Within3 talks about the “invisible college” — the hidden network of experts that actually shapes clinical and commercial decisions. How do you map that, and what does a pharma team do differently once they can see it? Insights management is often treated as a cost center — a reporting function that feeds decks nobody reads. How do you make the business case for it as a revenue driver, and who in the org actually has to own it? In data quality, engagement, and transparency — what are the three non-negotiables? What’s the anti-pattern you keep seeing, and what does the fix actually look like in practice? Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  7. Jun 12

    The Future Label: Building AI Innovation Backward from Adoption

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Ayelet Geva, Innovation and Business Development at the Jusidman Cancer Center at Sheba Medical Center. Most oncology innovations die, not in the lab, but in the gap between clinical proof and real-world implementation. Geva’s seen what separates the solutions that scale from the ones that stall: it’s not the science. It’s whether you’ve answered the hard questions — who pays, who changes their workflow, and what adoption looks like outside a controlled study — before you’ve run your first trial. In this episode, Geva shares how her unit approaches innovation differently: starting with the intended use, the value proposition, and the “future label,” then working backwards into evidence, data, partnerships, and adoption models. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell us about your journey to the Sheba Medical Center. What does a typical work week look like to you? What does value creation mean to you? Is it a clinical outcome, workflow efficiency, operational cost reduction, or something else entirely? How does the Cancer Center think about capturing value from the innovation that you develop? What are three concrete things an oncologist should try out with AI this year? What is the biggest anti-pattern in your industry today? Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  8. Jun 5

    Designing MedTech from the Market Backwards

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Theo Mastrokostopoulos, Co-Founder and CEO at Pleo Flow. This episode explores one of the biggest anti-patterns in medtech: building a technology first and only later trying to figure out who buys it, how it gets reimbursed, and whether the economics work. Mastrokostopoulos argues that successful medtech companies must design from commercialization backwards — starting with what you sell, how you price it, who buys it, and how those answers should shape product design from day one. The conversation uses Mastrokostopoulos’s current company, Pleo Flow, as a live example of how to align patient safety, physician usability, reimbursement, and hospital economics early. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell us about your journey to Pleo Flow. A lot of companies say, ‘Let’s collect some clinical data, let’s see what we have, then we’ll see.’ But you believe in what you sell, how you price it, and who buys it as a way to feed the product design from day one. Do you think your way is the best way? How do you create value for the patients, the physicians, and the company? How do you capture value? How do you price it? What are your plans for 2026 with Pleo Flow? What are three things you want to do for your patients? For cardiovascular devices, what is the biggest anti-pattern in this industry? This is not a statistically valid number, but you do have your own sample – what percentage of MedTech startups fall on the sword of Damocles of this anti-pattern? Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

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About

The Life Sciences Today podcast by Healthcare IT Today brings you strategic conversations with life science founders. Hosts Danny Lieberman and John Lynn and their guests reveal the patterns behind sustainable competitive advantages. Subscribe to the Clear Thinking newsletter by Danny Lieberman for deeper pattern analysis.

Information

  • Creator
    Danny Lieberman and John Lynn
  • Years Active
    2025 - 2026
  • Episodes
    71
  • Rating
    Clean
  • Copyright
    © 2025
  • Show Website
    Life Sciences Today