Life Sciences Today

Danny Lieberman and John Lynn

The Life Sciences Today podcast by Healthcare IT Today brings you strategic conversations with life science founders. Hosts Danny Lieberman and John Lynn and their guests reveal the patterns behind sustainable competitive advantages. Subscribe to the Clear Thinking newsletter by Danny Lieberman for deeper pattern analysis.

  1. 2D AGO

    Brain Health, Behavior, and the Future of Dementia Prevention

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is David Bates, Founder and CEO at Linus Health. I talk with David Bates about Linus Health’s mission to transform brain health from late-stage “sick care” to proactive, preventive care. David explains his journey from signal detection research and investing in built-environment technologies to founding Linus Health around the insight that behavior is the primary observable output of the brain. We discuss Linus’s 3-minute digital cognitive assessments that turn rich behavioral signals into thousands of digital biomarkers, enabling highly sensitive, objective measurement of cognition and early detection of impairment years before symptoms. Our conversation covers the company’s focus on primary care and health systems as core customers, revenue and ROI in fee-for-service and value-based care, and Linus’s data moat of large, diverse, longitudinal datasets. We explore how clinically integrated, consumer-accessible tools could make brain health monitoring continuous—like a “blood pressure cuff for the brain”—and why this paradigm shift is critical for both healthcare delivery and drug development. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: How did your background in signal detection, multimodal sensing, and investing lead you to found Linus Health? What does Linus Health’s platform actually do, and how are your digital assessments different from traditional paper-based cognitive tests? Who are your main customers today (primary care, health systems, pharma, payers), and how do you create and capture value across these different buyer types? How do you translate thousands of digital biomarkers and AI/ML models into clinically meaningful insights, and how often are your models updated? What is your long-term vision? Is the biggest opportunity in supporting drug development, or in becoming a clinically integrated, mass-market “Internet of bodies” brain health platform for consumers? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

    40 min
  2. 12/26/2025

    Real-Time Pharma Insights: Philip Poulidis on Scaling ODAIA AI

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Philip Poulidis, CEO at Toronto-based ODAIA. Poulidis is tackling one of pharma’s biggest bottlenecks: slow, siloed commercial analytics. Spun out of academic research, ODAIA’s real-time AI platform unifies patient and HCP journey data, replacing months-old reports with dynamic insights that help reps, liaisons, and marketers target the right physicians at the right time — improving prescriptions, outcomes, and patient access. regulated by the USDA/FDA. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell me about your journey. Tell me about ODAIA AI. Who are your customers? How do you create value? How do you capture value from customers? What are three things you want to do for your customers in the next 12-18 months? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

    32 min
  3. 12/19/2025

    Freeze-Drying the Future: 43 Years of Innovation at OFD

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Walt Pebley, Chief Scientific Officer at OFD Life Sciences. With over four decades in lyophilization, Walt Pebley has helped OFD become the gold standard in stabilizing probiotics, biologics, and therapeutics. His journey — from personal tragedy to pioneering new delivery platforms — highlights how freeze drying shapes the future of medicine, from shelf-stable powders to novel formats for pain, diabetes, and neurology drugs, food, and dietary supplements regulated by USDA/FDA. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell me about your journey. Tell me about OFD Life Sciences. Who are your customers? How do you create value? How do you capture value from customers? What are three things you want to do for your customers in the next 12-18 months? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

    34 min
  4. 12/12/2025

    Large Quantitative Models with SandboxAQ

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Tiffany Callahan, Lead Architect of Agentic AI Systems at SandboxAQ. As a physicist, I love her approach to Large Quantitative Models trained on physics, chemistry, biology, and math to model the real world. Most of the companies in this space are building statistical models by: integrating large datasets for target identification by analyzing genomic and multi-omic data virtual screening to identify promising drug candidates novel molecule design and property prediction (toxicity, efficacy, pharmacokinetics) clinical trial optimization through patient selection and outcome prediction drug repurposing by finding new uses for existing drugs Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell me about your journey. Tell me about SAIR. Who are your customers? How do you create value? How do you capture value from customers? What are three things you want to do for your customers in the next 12-18 months? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  5. 12/05/2025

    Evidexa - Validating Healthtech with Evidence

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Jeff Gombala, Founder and CEO at Evidexa. Jeff Gombala started Helios Innovation with an idea that seems obvious – use expert knowledge and AI models to validate healthtech and medtech products. We’re going to talk about Jeff’s journey, the value they are creating, how they’re turning that into a business, and where they want to take customers by 2026. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell me about your journey. How do you create value for your customers? How do you capture value? What are three things you’d like to achieve for your customers in the next 12 months? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

    36 min
  6. 11/28/2025

    Redefining Healthcare Research with Briya AIRE

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is David Lazerson, Co-Founder and CEO at Briya. Briya started in 2020 with a bold idea — using cryptography and zero-knowledge proofs to make healthcare data shareable, secure, and compliant. Fast forward to today, they’ve just launched Briya AIRE, a clinical-grade AI research platform that promises to let researchers ask questions in plain English and get scientifically robust answers back — without writing code. We’re going to talk about David’s journey, the value Briya is creating, how they’re turning that into a business, and where they want to take customers by 2026. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: What made you start with something as gnarly as zero-knowledge proofs for healthcare data? At what point did you realize infrastructure wasn’t enough, that people wanted insights, not just secure pipes? What customer conversations tipped you off that AI was the next layer? For a researcher using AIRE, what’s the moment when the lightbulb goes on? Which use case best shows the value — the one where you thought, ‘okay, this is working’? How quickly can a researcher go from a question in plain English to a publishable-level output? Validation is one thing — but startups live or die on turning that into repeatable business. What did you have to prove to your Series A investors to show Briya could cross that chasm? I know you probably can’t share exact revenue, but when investors leaned in, what was the strongest signal they saw that Briya wasn’t just another pilot project? Contracts signed, pipeline size, or something else? If we sit down again in 18 months, what would you want to point to as real traction? What’s the one thing you think customers will be most surprised that Briya can do for them by 2026? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  7. 11/21/2025

    Bioconvergence at The Israel Innovation Authority

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Shai Melcer, Head of the National Program for Bioconvergence at The Israel Innovation Authority. We kick this episode off by first learning what bioconvergence is. Then we talk about who The Israel Innovation Authority’s customers are. Next, we examine why this is such a unique opportunity for Israel. But no opportunity is without its competition, so we talk about how Melcer is competing with cyber and defense — which are huge sectors here. Melcer then also shares how he is competing against big companies like Sandbox AQ. Next, we discuss how The Israel Innovation Authority creates and captures value. Lastly, we conclude this episode with Melcer sharing three things he wants to do for his customers.  Check out the main topics of discussion for this episode of the Life Sciences Today podcast: What is bioconvergence? Who are your customers? Why is this a unique opportunity for Israel? How do you compete with cyber and defense, which are huge sectors here? How do you compete with companies like Sandbox AQ, which spun off from Google quantum computing, raised $950M, and just released the largest publicly available binding affinity dataset with co-folded 3d structures on Hugging Face?  How do you create value? How do you capture value from your customers? What are 3 things you want to do for your customers? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

  8. 11/14/2025

    From Math to Medicine: Yann Gaston-Mathé's Mission to Transform Drug Discovery with AI and Robotics

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Yann Gaston-Mathé, Co-Founder and CEO at Iktos. Iktos combines AI drug discovery with a robot chemist – AI designs novel compounds considering synthesis constraints, and robots automatically synthesize compounds (100 reactions in parallel vs 2 manual). Trained as a mathematical engineer, Yann Gaston-Mathé crossed from numbers into biology, carrying a belief that drug discovery could be faster, smarter, and more humane. With Iktos, he’s bringing that vision to life — combining generative AI and robotics to redesign how medicines are designed, made, and tested, with the goal of delivering better therapies in less time. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell me about your journey. Tell me about Iktos. Who are your customers? How do you create value? How do you capture value from customers? What are 3 things you want to do for your customers in the next 12-18 months? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple Podcasts Spotify iHeartRadio Amazon Music Pandora YouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube.  Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!

About

The Life Sciences Today podcast by Healthcare IT Today brings you strategic conversations with life science founders. Hosts Danny Lieberman and John Lynn and their guests reveal the patterns behind sustainable competitive advantages. Subscribe to the Clear Thinking newsletter by Danny Lieberman for deeper pattern analysis.