MOHIVATE

Mohi Sarawgee

Hosted by Dr. Mohi Sarawgee, a GP, MOHIvate is your doctor’s dose of heart and science — with just a touch of humour — because health and feeling good shouldn’t feel complicated. Each episode breaks down medicine and everyday science in a simple, thoughtful way, serving as a reminder that real health can still feel human. I hope you enjoy listening, learning, and carrying a little feel-good factor with you. Thank you for tuning in! Disclaimer: The information shared in this podcast is for educational and inspirational purposes only. It is not intended to be, and should not be taken as, personal medical advice, diagnosis, or treatment. Always seek the guidance of your own doctor or another qualified healthcare provider with any questions about your health, and never ignore or delay professional medical advice because of something you’ve heard here. The views expressed are my own and do not represent the views of any organizations or institutions I’m affiliated with.

  1. 4일 전

    32. Screen Time in Children | Raising a Generation in a World Nobody Saw Coming

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores screen time in children: the first episode on MOHIVATE dedicated entirely to children, and an honest conversation about what is actually happening inside a child’s developing brain, and what the science is telling us in a world none of us were prepared for. The episode begins with context. From smartphones and tablets, to a pandemic that made screens the only classroom and playground available, to the first generation of children growing up alongside artificial intelligence as a daily presence. This is the world today’s parents are navigating. Without a guidebook, and largely without support. The science covers language development, attention and dopamine, sleep and melatonin, the video deficit effect in infants, and the childhood myopia epidemic, including why outdoor light, not eye drops, is the prescription. Age-specific guidance runs from birth through adolescence, including what the research says about social media, cyberbullying, and the teenage brain. Dr Mohi Sarawgee introduces the Three C’s framework — Content, Context, and Child — a practical lens for families navigating screen time at every age, alongside evidence-based anchors for sleep, eye health, and real life. With clinical insight, fifteen years of consulting rooms, and a doctor’s deep respect for every parent doing their absolute best, this episode gives screen time the conversation it deserves. REFERENCES 1. Screen Time and Early Childhood Development Frontiers in Developmental Psychology — Systematic Scoping Review (2025) https://www.frontiersin.org/journals/developmental-psychology/articles/10.3389/fdpys.2024.1439040/full 2. Screen Time and Sleep Hale & Guan — Screen Time and Sleep, Systematic Review, Sleep Medicine Reviews https://pmc.ncbi.nlm.nih.gov/articles/PMC4437561/ 3. Screen Time and Myopia Ha et al. — JAMA Network Open (February 2025) — 45 studies, 335,524 individuals https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2830598 4. Book by Jonathan Haidt The Anxious Generation — Research and Evidence Base https://www.anxiousgeneration.com/research/the-evidence 5. Adolescent Mental Health and Social Media — Dr. Jean Twenge Research publications and evidence base — Dr. Jean Twenge, San Diego State University https://www.jeantwenge.com/research/ 6. NHS Mental Health of Children and Young People in England (2023) NHS England Digital — most recent UK data https://digital.nhs.uk/data-and-information/publications/statistical/mental-health-of-children-and-young-people-in-england/2023-wave-4-follow-up 7. UK Government — Children’s Social Media Consultation (2026) GOV.UK National Consultation — Growing Up in the Online World https://www.gov.uk/government/consultations/growing-up-in-the-online-world-a-national-consultation 8. UK Government — Screen Use by Children Under Five (March 2026) Independent Expert Report — Early Years Screen Time Advisory Group https://assets.publishing.service.gov.uk/media/69c53daf4a06660f085442a7/EYSTAG_report.pdf Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    29분
  2. 4월 23일

    31. Magic Mushrooms & Psilocybin | Experience, Meaning & the Return of Psychedelics

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores psilocybin, the compound found in magic mushrooms, tracing its journey from ancient sacred ceremony to some of the most rigorous clinical research in psychiatry today. The episode begins where the science begins. With language. When neuroscientists at Johns Hopkins first documented what psilocybin did to the human brain, they had to invent entirely new words to describe it. Ego dissolution. Oceanic boundlessness. Mystical type experience score. This episode explores why those words matter clinically, and what the Default Mode Network has to do with depression, addiction, and the way the brain finds its way back to itself. From Richard Nixon’s 1970 decision to classify psilocybin as a Schedule 1 drug, freezing decades of promising research, to landmark clinical trials, this episode covers the full story honestly. The science on terminal cancer anxiety, treatment resistant depression, addiction, and microdosing is examined carefully - where the evidence is strong, where it is thin, and what regulatory bodies worldwide are now saying. With clinical insight, personal perspective, and a thread that begins with Roald Dahl, this is a conversation about what happens when science refuses to stay buried. References 1.The 2006 Johns Hopkins Paper — The One That Changed Everything https://pubmed.ncbi.nlm.nih.gov/16826400/ 2.Psilocybin in Terminal Cancer Patients — 2016 Landmark Study https://pmc.ncbi.nlm.nih.gov/articles/PMC5367557/ 3.Psilocybin vs Escitalopram — NEJM 2021 https://www.nejm.org/doi/full/10.1056/NEJMoa2032994 4.Psilocybin and Smoking Cessation — The 80% Study https://pmc.ncbi.nlm.nih.gov/articles/PMC4286320/ 5.Default Mode Network and Depression — Key Neuroscience Paper https://pubmed.ncbi.nlm.nih.gov/24567117/ 6.Psilocybin and the Default Mode Network — Brain Imaging https://www.pnas.org/doi/10.1073/pnas.1119598109 7.Microdosing — James Fadiman Book Reference https://www.amazon.com/Psychedelic-Explorers-Guide-Therapeutic-Journeys/dp/1594774021 8.Microdosing Blinded Trials — Placebo Effects https://elifesciences.org/articles/62878 9.Psilocybin Safety Profile — The Lancet https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)61462-6/fulltext 10.Nixon, Ehrlichman and the War on Drugs https://edition.cnn.com/2016/03/23/politics/john-ehrlichman-nixon-drug-war-blacks-hippie/index.html 11.Australia Approves Psilocybin — TGA 2023 https://www.tga.gov.au/news/media-releases/tga-approves-mdma-and-psilocybin-use-ptsd-and-depression-australia-first 12.FDA Breakthrough Therapy Designation for Psilocybin https://compasspathways.com/compass-pathways-receives-fda-breakthrough-therapy-designation-for-psilocybin-therapy-for-treatment-resistant-depression/ 13.UK Innovative Licensing and Access Pathway — ILAP https://ir.compasspathways.com/News–Events-/news/news-details/2025/Compass-Pathways-Successfully-Achieves-Primary-Endpoint-in-First-Phase-3-Trial-Evaluating-COMP360-Psilocybin-for-Treatment-Resistant-Depression/default.aspx 14.Yale Program for Psychedelic Science https://medicine.yale.edu/psychiatry/research/clinics-and-programs/psychedelic/ 15.Johns Hopkins Centre for Psychedelic and Consciousness Research https://www.hopkinsmedicine.org/psychiatry/research/psychedelics-research 16.Imperial College London Centre for Psychedelic Research https://www.imperial.ac.uk/psychedelic-research-centre 17.R. Gordon Wasson — Seeking the Magic Mushroom, Life Magazine 1957 https://www.imaginaria.org/wasson/life.htm Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    28분
  3. 4월 15일

    30. Berberine | Promise, Pitfalls & Perspective

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores berberine, one of the most talked about metabolic supplements right now, bringing clarity to a conversation often shaped more by social media than by science. Berberine is a naturally occurring alkaloid with thousands of years of history in Ayurvedic and traditional Chinese medicine. This episode traces how it moved from gut medicine to metabolic science, unpacking the mechanisms behind its effects on blood sugar, insulin resistance, lipid metabolism, and the PCSK9 pathway, the same cholesterol target that billion dollar injectable medications were developed to address. The episode examines the clinical evidence honestly, including the landmark head to head comparison with metformin, the 2025 meta-analysis data, and the real limitations of the current evidence base. It covers who berberine is actually used in, what the safety and interaction profile looks like, and why formulation and dose matter more than most supplement labels suggest. With clinical insight and a GP’s perspective, this episode gives berberine the conversation it deserves. REFERENCES 1. Berberine and Metabolic Syndrome — 2025 Systematic Review and Meta-Analysis https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1572197/full 2. Berberine Health Outcomes — Overview of 54 Systematic Reviews https://link.springer.com/article/10.1186/s12906-025-04872-4 3. Berberine vs Metformin — Head to Head Trial. Zhang Y et al.  https://academic.oup.com/jcem/article/93/7/2559/2598177 4. Berberine as a Novel Cholesterol Lowering Drug — PCSK9 and LDL Receptor Mechanism Kong W et al. Nature Medicine, 2004 https://www.nature.com/articles/nm1135 5. Berberine PCSK9 Inhibition — Review Berberine: Ins and outs of a nature-made PCSK9 inhibitor https://www.excli.de/excli/article/view/5234 6. Berberine Bioavailability and Gut Microbiome https://www.mdpi.com/1424-8247/18/2/193 7. Berberine and NAFLD — 2024 Meta-Analysis https://pubmed.ncbi.nlm.nih.gov 8. Dihydroberberine vs Standard Berberine HCl — 2021 RCT https://pubmed.ncbi.nlm.nih.gov/35010998/ 9. Berberine and PCOS — 2024 Meta-Analysis https://pubmed.ncbi.nlm.nih.gov 10. Semaglutide Cardiovascular Outcomes — NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa1607141 11. Semaglutide Weight Loss — STEP Trial Wilding JPH et al. New England Journal of Medicine, 2021 https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 12. AMPK as Metabolic Master Switch — Review Hardie DG.  https://onlinelibrary.wiley.com/doi/10.1111/joim.12268 13. Berberine Drug Interactions — CYP450 Guo Y et al. https://pubmed.ncbi.nlm.nih.gov/21987089/ 14. Berberine Contraindication in Pregnancy Liu W et al. Available via PubMed safety data: https://pubmed.ncbi.nlm.nih.gov Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    26분
  4. 4월 9일

    29. Continuous Glucose Monitoring | Data, Patterns & Beyond the Hype

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores continuous glucose monitoring through the lens of metabolic health, bringing clarity to one of the most talked about and most misunderstood tools in modern wellness. The CGM is everywhere. On social media arms, in wellness programmes, in dinner party conversations. But what does it actually measure? What is the science genuinely telling us? And who actually needs one? This episode covers how CGMs work, what glucose patterns really mean, the science of glycaemic index and glycaemic load, why two people can eat the same meal and have completely different responses, and what advanced glycation end products tell us about long term health. It explores how to read your own data, what HbA1c misses, and who should and should not consider wearing one, with honest clinical guidance and no agenda. Grounded in science, personal experience, and a mild voluntary obsession with data, this is a warm, honest and genuinely useful conversation about glucose, metabolic health, and what your body has been trying to show you all along. References: 1. Glycaemic Index and Glycaemic Load — Food Reference University of Sydney International GI Database. Search GI and GL values for thousands of foods: https://glycemicindex.com/gi-search/ 2. Individual Variation in Glucose Response — The PREDICT Study Berry SE et al. Human postprandial responses to food and potential for precision nutrition. Nature Medicine. 2020;26:964–973. https://www.nature.com/articles/s41591-020-0934-0 PubMed: https://pubmed.ncbi.nlm.nih.gov/32528151/ 3. The 42 Factors — Further Reading The PREDICT study machine learning model used 42 individual factors to predict glucose response. For a detailed accessible breakdown of factors influencing blood glucose, see also: https://diatribe.org/diabetes-management/42-factors-affect-blood-glucose-surprising-update 4. Post-Meal Walking — 10 Minutes Immediately After Eating Hashimoto K et al. Positive impact of a 10-min walk immediately after glucose intake on postprandial glucose levels. Scientific Reports. 2025. https://www.nature.com/articles/s41598-025-07312-y Supporting systematic review: Engeroff T et al. After Dinner Rest a While, After Supper Walk a Mile? Sports Medicine. 2023;53(4):849–869. https://pubmed.ncbi.nlm.nih.gov/36715875/ 5. Soleus Pushup Pilot Study Elek D et al. The Efficacy of Soleus Push-Up in Individuals with Prediabetes: A Pilot Study. Sports (Basel). 2025;13(3):81. https://pmc.ncbi.nlm.nih.gov/articles/PMC11946342/ Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    23분
  5. 4월 1일

    28. Hay Fever | A Case Of Mistaken Identity

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores hay fever through the lens of immunology, bringing clarity to one of the most common and often underestimated conditions worldwide. Hay fever, or allergic rhinitis, is an immune response shaped by genetics, environment, and a system designed to protect you, reacting to something that was never meant to be a threat. Beneath the sneezing and the itchy eyes is a story about your immune system making a spectacular case of mistaken identity. This episode covers how sensitisation works, the three overlapping pollen seasons, the hidden food connection most people never realise, the relationship between hay fever and asthma, and why hay fever is getting worse globally, and what that means for the hundreds of millions of people living with it. Practical, clinically grounded, and with some tips that may genuinely change how you manage this season. References: 1. Global prevalence of allergic rhinitis:  Allergic Rhinitis: A Clinical and Pathophysiological Overview. Frontiers in Medicine, 2022. https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.874114/full 2. Pollen seasons lengthening. Anthropogenic climate change is worsening North American pollen seasons. Proceedings of the National Academy of Sciences, 2021. https://www.pnas.org/doi/10.1073/pnas.2013284118 3. UK pollen season. Climate Central — Pollen Season and Climate Change. https://www.climatecentral.org/climate-matters/pollen-season-climate-change 4. United airway disease : hay fever and asthma connection. United Airway Disease: Current Perspectives. Journal of Asthma and Allergy, PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC4872272/ 5. Oral Allergy Syndrome. Stanford Health Care. https://stanfordhealthcare.org/content/dam/SHC/clinics/menlo-medical-clinic/docs/Allergy/Oral%20Allergy%20Syndrome.pdf Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    24분
  6. 3월 26일

    27. Caffeine | The Wakefulness That Stays

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores caffeine beyond the morning habit, bringing clarity to the world’s most widely consumed psychoactive substance. Caffeine is not just a pick-me-up. It is a molecule with a thousand-year history, a fascinating pharmacology, and a surprisingly complex relationship with your body. This episode traces caffeine from its origins in the Ethiopian highlands, through the coffeehouses of the Ottoman Empire and the penny universities of Oxford, to the biology of what happens the moment it enters your bloodstream. The conversation covers how caffeine works in the brain, why your genetics determine how long it stays in your system, and what that means for your heart, your sleep, and your health. It explores the science behind energy drinks, the truth about decaf, the clinical reality of caffeine dependence, and emerging research linking caffeine to neurodegeneration. Alongside the science, the episode draws on history, culture, and a little Sufi poetry to place caffeine in its full human context, and asks what it means to consume something so powerful, so unconsciously. A grounded, science-based, and warmly delivered look at the molecule the world runs on, and what it is actually doing to you. References:  1. Cornelis MC, El-Sohemy A, Kabagambe EK, Campos H. Coffee, CYP1A2 Genotype, and Risk of Myocardial Infarction. JAMA. 2006;295(10):1135-1141. https://jamanetwork.com/journals/jama/fullarticle/202502 2.Silverman K, Evans SM, Strain EC, Griffiths RR. Withdrawal Syndrome after the Double-Blind Cessation of Caffeine Consumption. New England Journal of Medicine. 1992;327(16):1109-1114. https://www.nejm.org/doi/full/10.1056/NEJM199210153271601 3.Gardiner C, Weakley J, Burke LM, et al. The Effect of Caffeine on Subsequent Sleep: A Systematic Review and Meta-Analysis. Sleep Medicine Reviews. 2023;69:101764. https://pubmed.ncbi.nlm.nih.gov/36870101/ 4.Zhao Y, Lai Y, Konijnenberg H, et al. Association of Coffee Consumption and Prediagnostic Caffeine Metabolites With Incident Parkinson Disease. Neurology. 2024;102:e209201. https://www.neurology.org/doi/10.1212/WNL.0000000000209201 5.StatPearls. Caffeine Withdrawal. National Library of Medicine. Updated 2025. https://www.ncbi.nlm.nih.gov/books/NBK430790/ Comprehensive clinical reference on caffeine withdrawal including DSM-5 criteria, symptoms, and timeline. Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    30분
  7. 3월 19일

    26. Understanding Insulin | The Hormone That Brings Order

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores insulin beyond the usual association with diabetes, bringing clarity to one of the most important hormones in metabolism. Insulin is not just about blood sugar. It is central to how the body uses, stores, and manages energy every day. This episode explains how insulin works, how glucose moves through the body, and how balance is maintained after every meal through a clear and practical framework. The conversation explores insulin resistance, why it develops over time, and how it connects to prediabetes, type 2 diabetes, and other related conditions. It also outlines the role of lifestyle factors including diet, movement, sleep, and stress in shaping metabolic health. Alongside the science, the episode also draws on a personal story and a symbolic lens to connect these ideas to everyday life, and introduces a way of thinking about insulin as a system of order and structure within the body. A grounded, science-based look at how the body manages energy, and why understanding insulin is key to long-term health. References: 1. Insulin Resistance and Type 2 Diabetes – CDC https://www.cdc.gov/diabetes/about/insulin-resistance-type-2-diabetes.html 2. Insulin Resistance – StatPearls, NCBI https://www.ncbi.nlm.nih.gov/books/NBK507839/ 3. Prediabetes and Insulin Resistance – NIDDK, NIH https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance 4. Insulin Resistance – Cleveland Clinic https://my.clevelandclinic.org/health/diseases/22206-insulin-resistance Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    24분
  8. 3월 12일

    25. The Science of Clutter: Cognitive Load & Attention | Why Our Minds Need Space

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores the science of clutter and how the environments we live in influence attention, stress, and decision making. Research in neuroscience and behavioural psychology shows that visual clutter increases cognitive load and forces the brain to work harder to filter information. Over time this can contribute to mental fatigue, distraction, and decision fatigue. The episode examines how clutter interacts with attention regulation, stress physiology, eating behaviour, and everyday habits. It also looks at why the spaces people live in matter clinically, influencing safety, mobility, and how health behaviours unfold at home. Set within the wider context of modern life and information overload, this conversation invites listeners to reconsider their surroundings and the role physical space plays in supporting clarity, focus, and wellbeing. References: 1. Visual clutter and attention (Princeton Neuroscience Institute); McMains S., Kastner S. (2011) https://pubmed.ncbi.nlm.nih.gov/21228167/ Princeton Neuroscience Institute explanation of visual competition: https://ipalab.princeton.edu/document/296  2. Clutter and stress hormones (UCLA “Life at Home” study): Saxbe, D. E., & Repetti, R. L. (2010) https://doi.org/10.1177/0146167209352864 PDF:https://repettilab.psych.ucla.edu/wp-content/uploads/sites/302/2023/03/no-place-like-home.pdf  3. Cluttered environments and eating behaviour (Cornell study): Vartanian, L. R., Kernan, K. M., & Wansink, B. (2016) https://doi.org/10.1177/0013916516628178 4. Cognitive load theory: Sweller, J. (1988) https://doi.org/10.1207/s15516709cog1202_4 5. Behavioural activation and small task completion: Dimidjian, S. et al. (2011) https://doi.org/10.1016/j.cpr.2011.02.003 6.Indoor allergens and respiratory health: Arshad, S. H. (2010) https://doi.org/10.1016/j.jaci.2010.10.007 Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    27분

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소개

Hosted by Dr. Mohi Sarawgee, a GP, MOHIvate is your doctor’s dose of heart and science — with just a touch of humour — because health and feeling good shouldn’t feel complicated. Each episode breaks down medicine and everyday science in a simple, thoughtful way, serving as a reminder that real health can still feel human. I hope you enjoy listening, learning, and carrying a little feel-good factor with you. Thank you for tuning in! Disclaimer: The information shared in this podcast is for educational and inspirational purposes only. It is not intended to be, and should not be taken as, personal medical advice, diagnosis, or treatment. Always seek the guidance of your own doctor or another qualified healthcare provider with any questions about your health, and never ignore or delay professional medical advice because of something you’ve heard here. The views expressed are my own and do not represent the views of any organizations or institutions I’m affiliated with.