My Allergist Dad

My Allergist Dad
  • 5.0 (5)
  • Alternative Health
  • Updated Weekly

My Allergist Dad is the show where comedian Drew Zwetchkenbaum teams up with his real-life father - board-certified allergist and immunologist Dr. Z - to break down the mysteries of allergies . Every week they answer real questions from listeners and from Dr. Z’s own patients, mixing expert answers with father–son banter, jokes, and the occasional family story. New episodes every Monday!

  1. 5d ago

    MicroRNAs, COPD, and Lung Disease: How Tiny Regulators May Drive Chronic Inflammation (with Chris Dalldorf)

    Drew and Dr. Z welcome Dr. Chris Dalldorf, a computational biology and bioinformatics researcher at Brigham and Women’s Hospital, to discuss his machine-learning research on chronic obstructive pulmonary disorder (or COPD) and related lung diseases using large human lung tissue datasets. They clarify how COPD differs from asthma, why smoking is a major risk factor but not the sole cause, and how microRNAs regulate gene expression by silencing messenger RNAs.  Chris explains that smoking can strongly alter microRNA expression, that certain microRNAs (including microRNA-29) and mutations may be associated with COPD and IPF, and that proving causation in human disease is difficult. They also discuss extracellular matrix genes as potential drivers of fibrosis and how microRNA regulation of these genes could point toward future therapeutic approaches. 00:00 Meet Chris Dalldorf 00:26 Show Intro Theme 00:43 Providence Catch Up 02:41 Why Rhode Island 03:36 MicroRNA Basics 05:47 COPD Versus Asthma 11:40 Why Study COPD 13:24 Smoking And MicroRNA 14:42 Inflammation Parallels 19:37 Causation And Controls 24:09 Animal Models And Data 28:08 Machine Learning Role 32:41 Extracellular Matrix 33:34 Wrap Up And Disclaimer 📩 Have a question for the show?Email: myallergistdad@gmail.com

  2. Sep 7

    9 in 10 Babies Are Missing Key Gut Bacteria featuring Researcher and CEO Dr. Stephanie Culler

    Drew and Dr. Z welcome Dr. Stephanie Culler, co-founder and CEO of Persephone Biosciences, to discuss the infant gut microbiome and findings from the MyBabyBiome study, the largest U.S. infant gut microbiome study published. Culler explains that 9 in 10 U.S. babies are missing one or more key Bifidobacterium, and that by age two, babies with low or absent levels were three to four times more at risk for atopic dermatitis, food allergies, and asthma. They discuss how the microbiome develops from birth through early childhood, how factors like C-sections, antibiotics, and diet shape it, and why breast milk HMOs support Bifidobacterium. Culler describes Persephone’s infant/toddler synbiotic combining Bifidobacterium with HMOs, its safety, and parent- and clinician-reported improvements including sleep and mood, plus broader links between microbiome, inflammation, and immune function.00:00 Shocking Baby Biome Data00:39 Welcome And Guest Intro04:49 Microbiome Basics And Timing08:28 Allergy Desensitization Parallels11:39 Beyond Gut Skin And Airways14:32 Immune Programming First 100 Days15:27 Gut Brain And Behavior Links19:21 Diet Fiber And Lifestyle Synergy22:07 Safety And Modern Microbe Loss23:39 Founder Story From Cancer To Babies28:12 New Mom Moment And Missing Bifido29:30 Reflux Colic And EOE Questions35:06 Root Causes And Public Health40:40 Generational Shifts And Food Additives41:49 Product Details Discount And Wrap Up43:44 Final Takeaways And Disclaimer

  3. Aug 31

    Dr. Z’s Research Trial For a Breakthrough Cat Allergy Shot and Tryptase Testing

    In this episode of My Allergist Dad, Drew and Dr. Z discuss a phase 3 trial for severe cat allergy targeting the Fel d 1 allergen with a monoclonal antibody injection lasting about three months, improving ocular symptoms and reducing skin test reactivity, with potential seasonal/targeted use and related work in birch pollen.They also talk about a patient who experienced a life-threatening reaction during anesthesia induction for a hernia repair, including severe bronchospasm and hypotension, and how timely tryptase testing helped support that it was true anaphylaxis rather than medication side effects. Dr. Z explains baseline vs reaction tryptase levels, the mast cell activation formula, and why tryptase must be drawn within 2–3 hours, then shares that the patient is being referred to Brigham’s Drug Hypersensitivity and Desensitization Center to test likely triggers such as neuromuscular blocking agents and cefazolin (Ancef). 00:00 Cold Open Breakthrough00:34 Show Intro Theme00:51 Meet Drew and Dr Z01:14 Diet Restrictions Dinner02:34 Anesthesia Anaphylaxis Case06:17 Tryptase Test Explained09:33 Referral and Key Triggers12:35 Haircut Tangent and Shoutout14:40 Cat Allergy Shot Trial20:36 How Blocking Antibodies Work25:46 Timing Shots and Future Uses27:05 Wrap Up and Disclaimer📩 Have a question for the show?Email: myallergistdad@gmail.com

  4. Aug 17

    Autoimmune Conditions, Allergies & Control: Sydney on Living With Type 1 Diabetes and Hashimoto’s

    Drew and Dr. Z welcome Drew’s fiancée, Sydney, to discuss her experience living with two autoimmune diseases—Type 1 diabetes since age five and Hashimoto’s since adolescence—and how autoimmune conditions overlap with allergies through inflammation and the immune system. They explore genetic predisposition plus triggers, the importance of taking control of chronic illness through education and daily habits, and how technology like CGMs and insulin pumps has transformed diabetes management. The conversation covers nutrition, walking after meals, preparedness, and the mixed value of non-diabetics using CGMs. Dr. Z shares a case linking Hashimoto’s, celiac disease, and hives, and they discuss reducing inflammation, gluten-free eating, gut health, probiotics, and how medical advances have dramatically improved outcomes across many conditions.00:00 Welcome and Teaser00:36 Meet Sydney02:23 Sydney Autoimmune Story02:59 Autoimmune Continuum Explained06:16 Taking Back Control09:25 Diabetes Tech and CGMs12:06 Should Non Diabetics Track Glucose16:55 Hashimotos Celiac and Inflammation23:47 Medical Progress Then and Now30:06 Diabetes Camp and Daily Habits34:36 Gut Health Food Sensitivities38:32 Fasting Probiotics and Dog Talk43:09 Wrap Up and Final Thoughts📩 Have a question for the show?Email: myallergistdad@gmail.com

  5. Aug 10

    Cyclospora Outbreak: How to Protect Yourself + Gut Microbiome Recovery

    Drew and Dr. Z discuss the 2026 cyclospora outbreak and practical steps to reduce exposure, including washing hands, thoroughly scrubbing produce, cutting away bruised areas, and cooking produce to at least 158°F/70°C since washing alone can’t guarantee removal. They note CDC reports of at least 10,000 laboratory-confirmed domestic cases since May 1, 2026, and talk about how food-system factors limit individual control, while lifestyle and microbiome health may influence how severely someone is affected. Dr. Z shares an “aha” about chronic hives potentially worsening after unhealthy meals and alcohol due to liver strain, estrogen and histamine backup, and effects on mast cells, especially in menopausal women with fatty liver. They also cover rebuilding the microbiome after GI illness with improved diet and possible probiotics.00:00 Cyclospora Outbreak Intro00:35 Show Theme Song01:01 Fatty Liver And Hives06:29 Agency And Food Safety09:25 Cooking Produce Tips10:25 Where Cyclospora Comes From11:22 Taco Bell Talk14:12 Rebuilding The Microbiome16:00 Gut Parasites Q And A18:26 Wrap Up And Disclaimers📩 Have a question for the show?Email: myallergistdad@gmail.com

  6. Aug 3

    Following Your Passion and Getting Creative to Live a More Balanced Lifestyle with Lucas Foglia

    This week on My Allergist Dad, Drew and Dr. Z sit down with fine art photographer and longtime family friend Lucas Foglia to talk about health, happiness, and how lifestyle and mindset can shape stress, immunity, and overall well-being. Lucas shares the inspiration behind his book and exhibition Constant Bloom, which follows the painted lady butterfly migration from Kenya to Norway as a symbol of connection across borders, and describes turning photography into a purpose-driven way of living. They discuss balance and stress as both fuel and risk, the “dirt” and allergy conversation, why some people are more allergy-prone, and how food culture and dietary restrictions show up differently in the Bay Area versus Paris. He also recounts a powerful encounter in Tunisia that led him to volunteer with refugee resettlement groups and reflects on art, family connection, and living with meaning.00:00 Butterflies And Allergies Cold Open01:02 Show Intro And Guest Welcome02:36 San Francisco Check In03:09 From Photos To Film04:59 Purpose Fuels Health07:19 Doughnut Economics And Welfare11:17 Constant Bloom Migration Story13:37 Dirt Exposure And Allergy Debate16:35 Food Restrictions And Dinner Parties22:40 Stress Balance And Immunity26:57 Vaccines And Modern Anxiety28:29 Borders Migration And Meaning30:00 Closing Thoughts And Art Connection34:27 Outro And Medical Disclaimer 📩 Have a question for the show?Email: myallergistdad@gmail.com

  7. Jul 27

    Metabolomics, Machine Learning & the Future of Precision Medicine with Dr. Elizabeth O’Day of Olaris

    Drew and Dr. Z welcome Dr. Elizabeth O’Day, CEO, CSO, and founder of Olaris, to discuss how her company combines biology, metabolomics, and machine learning to create diagnostics that support real clinical decision-making. Liz shares how her brother’s childhood cancer experience motivated her to pursue tools that reduce today’s trial-and-error medicine and better match therapies to individuals. She explains biomarkers (genomic, transcriptomic, proteomic, and metabolomic), describing metabolites as small molecules that reflect real-time body function and are often the “fingerprint of phenotype.” The conversation focuses on Olaris’ urine-based test for kidney transplant recipients, which uses metabolite patterns to distinguish stable grafts from rejection, borderline rejection, or infection—conditions with opposite treatments—along with new work on a pediatric transplant assay to reduce reliance on biopsies.00:00 Meet Dr. Liz O'Day01:57 Olaris Mission Overview04:16 Why She Founded Olaris08:05 Precision Medicine In Practice11:05 Biomarkers And Phenotypes13:27 Metabolites 101 Explained14:30 Lifestyle, Diet, And The Metabolome19:12 Genes Versus Metabolites22:35 Urine Tests And Ancient Clues23:42 Metabolites Guide Immunity25:27 Transplant Test Explained27:32 Rejection Versus Infection29:37 Precision Medicine Landscape33:39 Pediatric Transplant Breakthrough36:12 Digestive Rest And Fruit Talk38:18 Coconut Stories And Metabolites40:11 Wrap Up And Future Promise41:43 Show Outro And Thanks📩 Have a question for the show?Email: myallergistdad@gmail.com

  8. Jul 6

    Allergy Doctor Reacts To Allergies Seen in Film & TV | My Allergist Dad

    FARE criticized the show Not Suitable for Work for portraying a character repeatedly eating shellfish despite an allergy and self-injecting epinephrine, then going to the ER for “adrenaline poisoning,” prompting Drew and Dr. Z to discuss how allergies are depicted in film and TV and what’s medically accurate. Dr. Z emphasizes epinephrine as the first-line treatment for anaphylaxis and explains why Benadryl is not adequate for life-threatening reactions, the need for emergency evaluation due to risks like biphasic reactions, and the real side effects and dosing concerns of epinephrine. They also address correct EpiPen technique, risks of incorrect injection (including to the neck), newer options like Auvi-Q and nasal epinephrine, and review portrayals from Hitch, Horrible Bosses, Malcolm in the Middle (poison oak timing and rash type), Royal Pains, Jury Duty Presents: Company Retreat, and Pulp Fiction, noting some accuracy but frequent exaggeration.00:00 FARE Calls Out TV Scene00:50 Show Setup And Alpha Gal01:28 Not Suitable For Work Breakdown02:52 Epinephrine Versus Benadryl06:41 Risks And Repeat Dosing10:26 Proper EpiPen Use11:40 Accidental Injection Effects15:46 Jury Duty And Chronic Hives20:16 Triggers And Enabling Factors21:38 Hitch Reaction Accuracy24:55 Poison Oak Mythbusting26:46 Royal Pains And Pulp Fiction29:12 Poison Ivy Timing Explained31:22 Wrap Up And Final Thoughts34:16 Medical Disclaimer 📩 Have a question for the show?Email: myallergistdad@gmail.com

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Ratings & Reviews

5
out of 5
5 Ratings

About

My Allergist Dad is the show where comedian Drew Zwetchkenbaum teams up with his real-life father - board-certified allergist and immunologist Dr. Z - to break down the mysteries of allergies . Every week they answer real questions from listeners and from Dr. Z’s own patients, mixing expert answers with father–son banter, jokes, and the occasional family story. New episodes every Monday!

Information

  • Creator
    My Allergist Dad
  • Years Active
    2025 - 2026
  • Episodes
    40
  • Rating
    Clean
  • Copyright
    © My Allergist Dad
  • Show Website
    My Allergist Dad

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