Neural Compass

Jimini Health
  • 5.0 (3)
  • Mental Health

If you work in mental health, invest in it, build in it, or just believe it deserves better than it is getting: Neural Compass is for you. Filter episodes by category to find exactly what you're looking for, from AI Meets the Clinic to Founders & Funders to Behavioral Science, right here: https://jiminihealth.com/podcast Every two weeks, Jimini Health co-founder Mark Jacobstein sits down with the scientists, clinicians, and executives who are actually moving the field. The conversations go deep. The guests are the real thing. Episodes have covered the clinical case for ketamine, the genomics of psychiatric diagnosis, what AI can and cannot do for behavioral health, and what it takes to reform mental healthcare from inside the system. Guests have included former National Institute of Mental Health director Tom Insel, Yale psychiatry chair John Krystal, and researchers and executives at the frontier of behavioral health and AI.

  1. 2d ago

    Healthcare was designed to fail, with Andy Slavitt

    People are already going to ChatGPT as their doctor. Not occasionally, habitually. Andy Slavitt ran Medicare and Medicaid under Obama, helped rescue healthcare.gov, and now invests in companies rebuilding how care gets delivered. His read: this is not a crisis. It is the first technology wave in healthcare that people actually want.

    Healthcare was designed to fail, with Andy Slavitt

  2. Jul 15

    The Science Advanced. The Patients Did Not Get Better, with Dr. Thomas Insel

    The National Institute of Mental Health funded 900 new research grants by this point last year. This year: 109. That gap is bigger than a budget number. Tom Insel ran that institution for 13 years, oversaw over $20 billion in research funding, and has spent the decade since trying to understand why the outcomes for patients still haven't moved nearly enough.

    The Science Advanced. The Patients Did Not Get Better, with Dr. Thomas Insel

  3. Jun 4

    The Measuring Gap: How AI and objective data are finally transforming psychiatric care, with Arpan & Amit Parikh

    You’ve likely heard that psychiatric progress is often stalled by subjective results. What is less understood is why the field remains slow to adopt in objective measurement even as other medical specialties thrive on hard data. Psychiatry faces a measurement gap. Dr. Arpan Parikh and Dr. Amit Parikh discusses measurement based Care, virtual health, and AI data synthesis. This is their honest account of why psychiatry must embrace measurement and how AI can finally bridge the clinical data gap.

    The Measuring Gap: How AI and objective data are finally transforming psychiatric care, with Arpan & Amit Parikh

  4. Jun 1

    Why Your Brain Functions Like a Specialized Swiss Army Knife, with Michael Platt

    Neuroeconomics, leadership, and brain health are essential for modern performance. Professor Michael Platt from UPenn explains why digital glass creates cognitive exhaustion. You have likely heard that our modern environment is destroying our focus. The scientific reason is that our evolutionary biology clashes with the digital tools we use every day. Professor Platt joins NeuralCompass to provide an expert account of how face-to-face connection remains the most powerful tool for leadership. This is an honest look at what your brain needs to thrive in a technological world.

    Why Your Brain Functions Like a Specialized Swiss Army Knife, with Michael Platt

  5. Apr 7

    Why Healthcare, Ever the Tech Laggard, Finally Got the AI Memo, with Jacob Effron

    What if healthcare’s biggest AI breakthroughs aren’t about new science—but about finally fixing systems that were never built to scale?In this episode of Neural Compass, Jacob Effron, Managing Director at Redpoint Ventures, joins Jimini’s Mark Jacobstein to explore where AI is already delivering real value in healthcare—and where hype still outpaces reality. Drawing on his experience at Flatiron Health and as an investor across AI, enterprise software, and healthcare, Jacob discusses why healthcare has become one of the fastest-adopting AI verticals, how real-world data actually creates value, and why tools that reduce clinician burden can unlock entirely new patient experiences. They cover:Why healthcare has emerged as a leading AI adoption verticalLessons from Flatiron Health on real-world data and evidenceWhat makes ambient clinical documentation a true “wedge” productHow AI can empower patients—not just cliniciansWhat separates generational health tech companies from short-lived hypeLearn more: jiminihealth.com

    Why Healthcare, Ever the Tech Laggard, Finally Got the AI Memo, with Jacob Effron

  6. Mar 18

    Talking “Conversational Doorknobs” & Broken Science with the Funniest Man in Psychology, Adam Mastroianni

    What if the hardest problems in psychology aren’t about data or statistics—but about how we talk, think, and decide what counts as truth?In this episode of Neural Compass, psychologist, writer, and internet favorite Adam Mastroianni joins Jimini’s Mark Jacobstein for a wide-ranging conversation about conversation itself. Drawing from experimental psychology, improv, and lived experience with anxiety and depression, Adam explores why good conversations feel rare, why science struggles to study the most important questions, and why mental health progress may require ideas that don’t fit into academic boxes. Along the way, he reflects on leaving academia, rethinking peer review, and what happens when you try to tell the truth instead of writing for journals. They cover:Why great conversations rely on “doorknobs,” not just questionsHow anxiety, status, and speed shape the way we talk to each otherWhat’s broken in modern science—and why legibility can be the enemy of discoveryWhy therapy works even when we don’t fully understand howHow imagining that “things could be better” fuels both progress and dissatisfactionLearn more: jiminihealth.com

    Talking “Conversational Doorknobs” & Broken Science with the Funniest Man in Psychology, Adam Mastroianni

  7. Feb 10

    Tech, AI, and the Future of Therapy, with Dr. Harry Ritter, Alma's CEO

    What if fixing mental healthcare isn’t about replacing clinicians—but finally giving them the systems they’ve always lacked?In this episode of Neural Compass, Dr. Harry Ritter, founder and CEO of Alma, joins Jimini’s Mark Jacobstein to explore how technology, insurance alignment, and new business models can unlock better mental health care at scale. Drawing on his experience as a physician, lawyer, and former Oscar Health executive, Harry explains why behavioral health has lagged in tech adoption, how the pandemic permanently reshaped care delivery, and why empowering independent clinicians may be the fastest path to access, quality, and sustainability. They cover:- Why behavioral health remained tech-averse for so long—and what changed- How Alma helps thousands of independent therapists accept insurance and scale- The hidden systems failures between payers, providers, and patients- Where AI can remove administrative burden without replacing clinicians- Why mental health may be the most powerful lever for preventive careLearn more: jiminihealth.com

    Tech, AI, and the Future of Therapy, with Dr. Harry Ritter, Alma's CEO

  8. Jan 6

    Can Stress Rewire the Brain—Across a Lifetime? with Dr. Nikolaos Daskalakis

    Why do some people emerge from trauma resilient, while others carry its effects for decades—or even generations?In this episode of Neural Compass, Harvard neuroscientist and psychiatrist Dr. Nikos Daskalakis joins Jimini’s Mark Jacobstein to unpack the biology of stress and PTSD. Drawing on decades of research spanning animal models, post-mortem human brain studies, and cutting-edge multi-omics, Dr. Daskalakis explains how genetics, early life stress, and later trauma interact to shape vulnerability, resilience, and mental health outcomes. The conversation explores how glucocorticoid signaling, immune–brain communication, and cell-type-specific transcriptional changes complicate our understanding of PTSD—and why simple, one-size-fits-all treatments continue to fall short.They cover:* The “three-hit” model of stress: genetics, early life experience, and adult trauma* Why cortisol and glucocorticoid signaling matter—but aren’t the whole story* What single-cell and multi-omic brain studies reveal about PTSD versus depression* The unresolved question of whether trauma can be biologically transmitted across generationsLearn more: jiminihealth.com

    Can Stress Rewire the Brain—Across a Lifetime? with Dr. Nikolaos Daskalakis
See All (25)

Ratings & Reviews

5
out of 5
3 Ratings

About

If you work in mental health, invest in it, build in it, or just believe it deserves better than it is getting: Neural Compass is for you. Filter episodes by category to find exactly what you're looking for, from AI Meets the Clinic to Founders & Funders to Behavioral Science, right here: https://jiminihealth.com/podcast Every two weeks, Jimini Health co-founder Mark Jacobstein sits down with the scientists, clinicians, and executives who are actually moving the field. The conversations go deep. The guests are the real thing. Episodes have covered the clinical case for ketamine, the genomics of psychiatric diagnosis, what AI can and cannot do for behavioral health, and what it takes to reform mental healthcare from inside the system. Guests have included former National Institute of Mental Health director Tom Insel, Yale psychiatry chair John Krystal, and researchers and executives at the frontier of behavioral health and AI.

Information

  • Creator
    Jimini Health
  • Years Active
    2025 - 2026
  • Episodes
    25
  • Rating
    Clean
  • Copyright
    © 24b78fd0-8b45-11f1-a959-15e72c268a32
  • Show Website
    Neural Compass