Neuroscience Perspectives

Del Monte Institute for Neuroscience at the University of Rochester
Neuroscience Perspectives

Immerse yourself in the fascinating world of neuroscience with our expert guests as they explore the mysteries of the brain and the latest breakthroughs in research with our host, John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester. Each episode features in-depth conversations with leading scientists, who unravel complex topics and tackle intriguing questions like: How does the brain shape our behavior? What role do genetics play in our health? How do early life experiences shape brain function and critical periods of brain development? Listen as they share their unique journeys to neuroscience research, lessons learned from the bench, and discoveries that transform our understanding of neurodevelopmental diseases and disorders like autism and Rett syndrome and neurodegenerative diseases like Alzheimer’s and Parkinson’s. Whether you’re a seasoned scientist or just curious about the brain, our podcast will spark your interest, expand your understanding of this dynamic field, and lift the veil on how leaders in brain research made it to where they are today. Don’t miss out on your journey into the depths of neuroscience with experts from around the world—subscribe now!

  1. Neuroscience & RNA Biology: How mRNA Decay Shapes Health & Disease

    MAR 27

    Neuroscience & RNA Biology: How mRNA Decay Shapes Health & Disease

    How does RNA biology influence cell function, gene expression, and disease mechanisms? In this episode of Neuroscience Perspectives, host John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester (UR), sits down with Lynne Maquat, PhD, director of the Center for RNA Biology at UR, and J. Lowell Orbison Endowed Chair and Professor of Biochemistry & Biophysics, to explore groundbreaking research in mRNA decay, cellular quality control, and translational research. Dr. Maquat, a world-renowned scientist, shares insights into how fundamental biochemistry, molecular biology, and biophysics drive scientific discovery—from understanding cystic fibrosis, fragile X syndrome, and intellectual disabilities to advancing cancer research, autism studies, and stem cell research. They also discuss the impact of mRNA vaccines, vaccine development, and COVID-19 on modern medicine. Beyond the lab, they dive into the importance of scientific integrity, mentoring scientists, research collaboration, and science education. 🔬 Discover how basic and applied research pave the way for personalized treatments, neurobiology breakthroughs, and scientific innovation. #Neuroscience #RNABiology #ScientificDiscovery #mRNADecay #GeneExpression #TranslationalResearch #CancerResearch #VaccineDevelopment #AutismResearch #StemCellResearch #ScienceEducation #ScienceCommunication 🧠 Stay Connected Subscribe: https://www.youtube.com/@URNeuroscience X: https://x.com/URNeuroscience BlueSky: https://bsky.app/profile/urneuroscience.bsky.social LinkedIn: https://www.linkedin.com/company/urneuroscience/ 🧠 Experts in this Episode: Lynne Maquat, PhD: https://www.urmc.rochester.edu/people/112359023-lynne-e-maquat John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe 🧠 Labs Mentioned: Maquat Lab: https://www.urmc.rochester.edu/labs/maquat Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG

    34 min
  2. Your Brain & Perception: Using Science to Understand How We See the World

    FEB 27

    Your Brain & Perception: Using Science to Understand How We See the World

    How brain dynamics, perception, and neural processing offer a deeper understanding of how brain activity shapes our understanding of the world. Christopher Moore, PhD, associate director of the Carnegie Institute of Brain Science and professor of Neuroscience at Brown University, joins Neuroscience Perspectives host John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester, in a fascinating discussion that includes why the term neuroscience may be outdated. Dive into Moore’s research that studies neocortical dynamics – changes in brain activity at the millisecond to the second timescale—and how his lab aims to understand the mechanisms at play and what these changes mean for perception. He and Dr. Foxe also share how they met during a pivotal moment in their careers, which was also a profound moment in neuroscience research. #neuroscience #brainscience #perception #podcast 🧠Stay Connected Subscribe: https://www.youtube.com/@URNeuroscience X: https://x.com/URNeuroscience BlueSky: https://bsky.app/profile/urneuroscience.bsky.social LinkedIn: https://www.linkedin.com/company/urneuroscience/ 🧠Experts in this Episode: Christopher Moore, PhD: https://vivo.brown.edu/display/cm78 John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe 🧠Labs Mentioned: The Moore Lab: https://www.themoorelab.org/ Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG

    35 min

  3. JAN 30

    Recovering From Stroke - How Physical Therapy & Neuroscience are Advancing Care

    The intersection of stroke rehabilitation & neuroscience research is transforming our understanding of the brain and recovery after a stroke. Catherine Lang, PT, PhD, Barbara J Norton Professor of Physical Therapy, Professor of Neurology and Occupational Therapy, and Associate Director of the Movement Science Program at the University of Washington in St. Louis, shares expert insights into stroke therapy, the challenges of regaining motor function, and how personal and environmental factors impact rehabilitation outcomes. Dr. Lang is a WashU graduate who completed her postdoctoral studies in a neuroscience lab at the University of Rochester School of Medicine and Dentistry. She shares how the education and mentorship she received played a role in the mentor she is today. She also gives insight into how growing up in rural Vermont influenced her interest in movement. Join Dr. Lang, and guest host, Jeff Koslofsky, host of The Next Steps Podcast from the University of Rochester School of Medicine and Dentistry, for this enlightening conversation. Don’t forget to like, comment, and follow! #neuroscience #stroke #réhabilitation #brain #motorcontrol #neuroplasticity #therapy #strokerecovery 🧠Stay Connected Subscribe: https://www.youtube.com/@URNeuroscience X: https://x.com/URNeuroscience BlueSky: https://bsky.app/profile/urneuroscience.bsky.social 🧠Check out The Next Steps Podcast: https://www.youtube.com/playlist?list=PLhIRpvrMLisrZXbvS3wDHGp_Ke9NE167u 🧠Experts in this Episode Catherine Lang, PT, PhD: https://pt.wustl.edu/people/catherine-lang-pt-phd-fapta/ Lang Research Profile: https://profiles.wustl.edu/en/persons/catherine-lang

    17 min
  4. What Happens When You Combine AI and Neuroscience?

    12/19/2024

    What Happens When You Combine AI and Neuroscience?

    Can we predict brain health across a lifetime? Just as a knee injury at 20 might cause problems later, researchers are exploring how early brain experiences shape future brain health. In this episode of Neuroscience Perspectives, Dr. Randy McIntosh, Professor and Director at the Institute for Neuroscience and Neurotechnology at Simon Fraser University, discusses groundbreaking insights into brain health, neuroscience, and AI with Dr. John Foxe, Director of the Del Monte Institute for Neuroscience. Learn about the Virtual Brain, an open-source neuroscience platform that simulates human brain function, offering new ways to understand conditions like stroke, epilepsy, and neurodegenerative diseases. Discover how technology, artificial intelligence, and neuroscience are converging to unlock the secrets of the human brain. Virtual Brain: https://www.thevirtualbrain.org/tvb/zwei 🧠Stay Connected Subscribe: https://www.youtube.com/@URNeuroscience X: https://x.com/URNeuroscience BlueSky: https://bsky.app/profile/urneuroscience.bsky.social 🧠 Experts in this Episode John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe Randy McIntosh, PhD: https://www.sfu.ca/bpk/about/people/faculty/randy-mcintosh.html 🧠Labs Mentioned Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG McIntosh Lab: https://www.armcintosh.com/home #brain #science #podcast

    28 min
  5. Unlocking the Brain's Communication Hub: The Power of the Thalamus with Dr. S. Murray Sherman

    11/19/2024

    Unlocking the Brain's Communication Hub: The Power of the Thalamus with Dr. S. Murray Sherman

    In this special episode of Neuroscience Perspectives, host John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester, sits down with S. Murray Sherman, PhD, Maurice Goldblatt Professor of Neurobiology at the University of Chicago, in Chicago at the annual Society for Neuroscience (SfN) conference. Sherman is a neuroscientist known for his groundbreaking work on the thalamus. Dive into a compelling conversation that unravels how the thalamus plays a pivotal role as the brain's relay center, transforming sensory input into meaningful perceptions and actions. Discover how Dr. Sherman's research sheds light on the thalamus's intricate connections to cortical regions, revealing its role in shaping critical cognitive functions. From vision to decision-making, his work was integral in informing the understanding of the visual pathway from the retina through the thalamus to the cortex, and it also revealed other cortical areas organized in parallel to direct connections. Learn how mentors and a bit of luck played critical roles in his journey, including Nobel laureates Richard Feynman, PhD, Roger Sperry, PhD, and Ray Guillery, PhD, who would become Sherman's longtime collaborator. Link to Sherman's SfN profile piece. Whether you're a neuroscientist or just interested in the brain —listen, learn, and subscribe to Neuroscience Perspectives today!

    26 min
  6. Exploring the Genetic Dance of Neurons: What Roundworms Reveal About Behavior

    10/25/2024

    Exploring the Genetic Dance of Neurons: What Roundworms Reveal About Behavior

    In this episode of Neuroscience Perspectives, we dive into the microscopic world of C. elegans—tiny roundworms that are revolutionizing our understanding of genetics and behavior. Join host John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester as he chats with Doug Portman, PhD, the Donald M. Foster Professor of Biomedical Genetics, Biology, and Neuroscience, at URMC. Portman’s research unravels the intriguing ways that biological sex shapes neural development and influences behaviors, like the eternal quest for food versus the search for a mate. Discover how these unassuming creatures serve as a powerful model for understanding complex questions about the brain. What happens in the male C. elegans brain when the urge to find a mate overrides the basic need to eat? And how can these insights inform our understanding of sex differences in human health and disease susceptibility? Whether you’re a neuroscience enthusiast or just curious about how tiny organisms can help answer big questions—listen, learn, and subscribe to Neuroscience Perspectives today!

    33 min
  7. How a quest to find solutions for vision loss- turned a clinician into a scientist

    09/19/2024

    How a quest to find solutions for vision loss- turned a clinician into a scientist

    José Alain Sahel, MD, is a distinguished professor, eye and ear foundation professor, and chair of the Department of Ophthalmology at the University of Pittsburgh School of Medicine. He is also the director of the UPMC Vision Institute. Dr. Sahel is a leading expert in retinal diseases and vision restoration research and is a pioneer in optogenetic vision restoration. This therapeutic technique uses genetically modified cells in the retina to express light-sensitive proteins and could help patients who are blind or visually impaired because of a genetic defect. His research has also helped to develop several other interventions for vision impairment—including stem cell implantation, gene therapy, innovative pharmacologic approaches, and the artificial retina. Dr. Sahel was the keynote speaker at the 33rd Biennial Center for Visual Science Symposium at the University of Rochester. He joins John Foxe, PhD, for this episode of Neuroscience Perspectives.

    28 min
  8. What helped launch leaders in neuroscience into a lifetime of learning

    08/22/2024

    What helped launch leaders in neuroscience into a lifetime of learning

    Is there a defining moment that set you on your current path? In this episode of Neuroscience Perspectives, we’re revisiting origin stories – what launched leading neuroscientists into a lifetime of learning and interest in the brain. Host: John Foxe, PhD, director of the Del Monte Institute for Neuroscience Guests (in order of appearance): Nathan A. Smith, PhD, associate dean for Equity & Inclusion for Research and Research Education and associate professor of Neuroscience at the University of Rochester School of Medicine School of Medicine and Dentistry, Full Episode: https://urmc.info/1G5 Fan Wang, PhD, professor, Brain and Cognitive Sciences, McGovern Institute, MIT, Full Episode: https://urmc.info/1G7 Takao Hensch, PhD, professor of Neurology at Harvard Medical School at Boston Children’s Hospital and of Molecular and Cellular Biology at Harvard’s Center for Brain Science, Full Episode: https://urmc.info/1G4 Jessica Cardin, PhD, associate professor, and vice chair of the Neuroscience Department at Yale School of Medicine, Full Episode: https://urmc.info/1G6 Kia Nobre, PhD, director of the Center for Neurocognition and Behavior at the Wu Tsai Institute at Yale University, Full Episode: https://urmc.info/1G3

    9 min
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    About

    Immerse yourself in the fascinating world of neuroscience with our expert guests as they explore the mysteries of the brain and the latest breakthroughs in research with our host, John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester. Each episode features in-depth conversations with leading scientists, who unravel complex topics and tackle intriguing questions like: How does the brain shape our behavior? What role do genetics play in our health? How do early life experiences shape brain function and critical periods of brain development? Listen as they share their unique journeys to neuroscience research, lessons learned from the bench, and discoveries that transform our understanding of neurodevelopmental diseases and disorders like autism and Rett syndrome and neurodegenerative diseases like Alzheimer’s and Parkinson’s. Whether you’re a seasoned scientist or just curious about the brain, our podcast will spark your interest, expand your understanding of this dynamic field, and lift the veil on how leaders in brain research made it to where they are today. Don’t miss out on your journey into the depths of neuroscience with experts from around the world—subscribe now!

    Information

    • Creator
      Del Monte Institute for Neuroscience at the University of Rochester
    • Years Active
      2023 - 2025
    • Episodes
      28
    • Rating
      Clean
    • Copyright
      © Del Monte Institute for Neuroscience at the University of Rochester
    • Show Website
      Neuroscience Perspectives

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