Neuroscience Perspectives

Del Monte Institute for Neuroscience at the University of Rochester

Immerse yourself in the fascinating world of neuroscience with our expert guests as they explore the mysteries of the brain and the latest breakthroughs in research with our host, John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester. Each episode features in-depth conversations with leading scientists, who unravel complex topics and tackle intriguing questions like: How does the brain shape our behavior? What role do genetics play in our health? How do early life experiences shape brain function and critical periods of brain development? Listen as they share their unique journeys to neuroscience research, lessons learned from the bench, and discoveries that transform our understanding of neurodevelopmental diseases and disorders like autism and Rett syndrome and neurodegenerative diseases like Alzheimer’s and Parkinson’s. Whether you’re a seasoned scientist or just curious about the brain, our podcast will spark your interest, expand your understanding of this dynamic field, and lift the veil on how leaders in brain research made it to where they are today. Don’t miss out on your journey into the depths of neuroscience with experts from around the world—subscribe now!

  1. RE-RELEASE: Jessica Cardin, PhD - From Daydreaming To Laser Focus How Your Brain Changes

    AUG 21

    RE-RELEASE: Jessica Cardin, PhD - From Daydreaming To Laser Focus How Your Brain Changes

    In this episode of Neuroscience Perspectives, take on the complex circuits of the brain with Jessica Cardin, PhD, professor of neuroscience at Yale University School of Medicine. Join host John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester, as he and Dr. Cardin discuss how brain states shift—from zoning out to laser focus—and the chemical signals and non-neuronal cells that help drive those changes. Discover how her lab is harnessing new technologies and big data approaches, including machine learning, to unravel how the brain integrates countless signals to guide decision-making and behavior. From exploring autism- and schizophrenia-related genes to studying models of aging and Alzheimer’s disease, Cardin’s research highlights both the promise and the challenges of understanding such a complex system. Subscribe to Neuroscience Perspectives today! #podcast #neuroscience #science #research #brain Stay Connected Subscribe: https://www.youtube.com/@URNeuroscience X: https://x.com/URNeuroscience BlueSky: https://bsky.app/profile/urneuroscience.bsky.social LinkedIn: https://www.linkedin.com/company/urneuroscience/ Experts in this Episode: Jessica Cardin, PhD: https://medicine.yale.edu/profile/jess-cardin/ John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe Labs Mentioned: Cardin Lab: https://cardinlab.org Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG

    24 min
  2. Can the Brain Help Predict Chronic Pain Risk

    JUL 24

    Can the Brain Help Predict Chronic Pain Risk

    In this episode of Neuroscience Perspectives, we explore one of medicine’s most complex and pervasive challenges—chronic pain. Host John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester, sits down with Paul Geha, MD, associate professor of Psychiatry, Neuroscience, Neurology, and Dentistry at the University of Rochester Medical Center. Together, they unpack the ways our brains perceive pain and the impact it can have on well-being.Dr. Geha shares his research into how brain connectivity and structure change in patients with chronic pain—and how these changes might help us predict who is at risk for conditions like low back pain or failed surgery outcomes. They discuss the psychological dimensions of pain, the challenges of diagnosis and treatment, and how research is charting a new course to change traditional injury-based models of pain.Could brain biomarkers reveal who is most vulnerable to chronic pain? Might psychedelics offer a new avenue for relief? And how can science better serve the millions suffering from pain that cannot be quantified in an exam or on a scan? ☝️ Be sure to follow and like: Neuroscience Perspectives! 🧠 Stay Connected Subscribe: https://www.youtube.com/@URNeuroscienceX: https://x.com/URNeuroscienceBlueSky: https://bsky.app/profile/urneuroscience.bsky.socialLinkedIn: https://www.linkedin.com/company/urneuroscience 🧠 Experts in this Episode: Paul Geha, MD: https://www.urmc.rochester.edu/people/112361971-paul-geha John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe🧠 Labs Mentioned: Geha Lab: https://www.urmc.rochester.edu/labs/geha Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG

    38 min
  3. Exploring the Impact of Environmental Chemicals on Brain Health

    APR 25

    Exploring the Impact of Environmental Chemicals on Brain Health

    Dr. Deborah Cory-Slechta is a leading researcher at the University of Rochester. She is a professor with appointments in Environmental Medicine, Neuroscience, and Public Health Sciences. She co-leads the University’s Intellectual and Developmental Disabilities Research Center Animal Behavior and Neurophysiology Core. She has chaired the Department of Environmental Medicine and led its National Institute of Environmental Health Sciences Core Center Grant. Her research explores the effects of environmental chemicals—such as air pollution, metals, and pesticides—on brain health. With decades of expertise, Dr. Cory-Slechta discusses the impact that exposures to chemicals in our environment have on neurodegenerative and neurodevelopmental disorders. Learn about the crucial intersection of neuroscience, toxicology, and public health. And how the passion to give back drives Dr. Cory-Slechta. #neuroscience #environmentalhealth #toxicology #podcast 🧠Stay Connected Subscribe: https://www.youtube.com/@URNeuroscience X: https://x.com/URNeuroscience BlueSky: https://bsky.app/profile/urneuroscience.bsky.social LinkedIn: https://www.linkedin.com/company/urneuroscience/ 🧠Experts in this Episode: John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe Deborah Cory-Slechta, PhD: https://www.urmc.rochester.edu/people/112358303-deborah-a-slechta 🧠Labs & Institutes Mentioned: Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG Cory-Slechta Lab: https://www.urmc.rochester.edu/labs/cory-slechta Institute for Human Health and the Environment: https://www.urmc.rochester.edu/institute-for-human-health-and-the-environment Environmental Health Sciences Center: https://www.urmc.rochester.edu/environmental-health-sciences

    42 min
  4. Neuroscience & RNA Biology: How mRNA Decay Shapes Health & Disease

    MAR 27

    Neuroscience & RNA Biology: How mRNA Decay Shapes Health & Disease

    How does RNA biology influence cell function, gene expression, and disease mechanisms? In this episode of Neuroscience Perspectives, host John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester (UR), sits down with Lynne Maquat, PhD, director of the Center for RNA Biology at UR, and J. Lowell Orbison Endowed Chair and Professor of Biochemistry & Biophysics, to explore groundbreaking research in mRNA decay, cellular quality control, and translational research. Dr. Maquat, a world-renowned scientist, shares insights into how fundamental biochemistry, molecular biology, and biophysics drive scientific discovery—from understanding cystic fibrosis, fragile X syndrome, and intellectual disabilities to advancing cancer research, autism studies, and stem cell research. They also discuss the impact of mRNA vaccines, vaccine development, and COVID-19 on modern medicine. Beyond the lab, they dive into the importance of scientific integrity, mentoring scientists, research collaboration, and science education. 🔬 Discover how basic and applied research pave the way for personalized treatments, neurobiology breakthroughs, and scientific innovation. #Neuroscience #RNABiology #ScientificDiscovery #mRNADecay #GeneExpression #TranslationalResearch #CancerResearch #VaccineDevelopment #AutismResearch #StemCellResearch #ScienceEducation #ScienceCommunication 🧠 Stay Connected Subscribe: https://www.youtube.com/@URNeuroscience X: https://x.com/URNeuroscience BlueSky: https://bsky.app/profile/urneuroscience.bsky.social LinkedIn: https://www.linkedin.com/company/urneuroscience/ 🧠 Experts in this Episode: Lynne Maquat, PhD: https://www.urmc.rochester.edu/people/112359023-lynne-e-maquat John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe 🧠 Labs Mentioned: Maquat Lab: https://www.urmc.rochester.edu/labs/maquat Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG

    34 min
  5. Your Brain & Perception: Using Science to Understand How We See the World

    FEB 27

    Your Brain & Perception: Using Science to Understand How We See the World

    How brain dynamics, perception, and neural processing offer a deeper understanding of how brain activity shapes our understanding of the world. Christopher Moore, PhD, associate director of the Carnegie Institute of Brain Science and professor of Neuroscience at Brown University, joins Neuroscience Perspectives host John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester, in a fascinating discussion that includes why the term neuroscience may be outdated. Dive into Moore’s research that studies neocortical dynamics – changes in brain activity at the millisecond to the second timescale—and how his lab aims to understand the mechanisms at play and what these changes mean for perception. He and Dr. Foxe also share how they met during a pivotal moment in their careers, which was also a profound moment in neuroscience research. #neuroscience #brainscience #perception #podcast 🧠Stay Connected Subscribe: https://www.youtube.com/@URNeuroscience X: https://x.com/URNeuroscience BlueSky: https://bsky.app/profile/urneuroscience.bsky.social LinkedIn: https://www.linkedin.com/company/urneuroscience/ 🧠Experts in this Episode: Christopher Moore, PhD: https://vivo.brown.edu/display/cm78 John Foxe, PhD: https://www.urmc.rochester.edu/people/112360965-john-j-foxe 🧠Labs Mentioned: The Moore Lab: https://www.themoorelab.org/ Frederick J. and Marion A. Schindler Cognitive Neurophysiology Lab: https://urmc.info/1RG

    35 min

About

Immerse yourself in the fascinating world of neuroscience with our expert guests as they explore the mysteries of the brain and the latest breakthroughs in research with our host, John Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester. Each episode features in-depth conversations with leading scientists, who unravel complex topics and tackle intriguing questions like: How does the brain shape our behavior? What role do genetics play in our health? How do early life experiences shape brain function and critical periods of brain development? Listen as they share their unique journeys to neuroscience research, lessons learned from the bench, and discoveries that transform our understanding of neurodevelopmental diseases and disorders like autism and Rett syndrome and neurodegenerative diseases like Alzheimer’s and Parkinson’s. Whether you’re a seasoned scientist or just curious about the brain, our podcast will spark your interest, expand your understanding of this dynamic field, and lift the veil on how leaders in brain research made it to where they are today. Don’t miss out on your journey into the depths of neuroscience with experts from around the world—subscribe now!