Patchwork Podcast

Making health easy

We talk about esoteric and cutting-edge health research with many guests that fixes people's health problems via nutrition, DNA analysis and more while being as low effort as it was in the 1950s. patchworkfood.substack.com

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  1. 28.05.2025

    How I Thrived on 6,000 Calories a Day 🚴‍♂️ - Billy Craig

    Unlocking the secrets of metabolic health! In this episode, we talked about Billy Craig's incredible journey, from professional mountain biking to consuming 6,000 calories a day as part of a bold diet experiment. Billy shares insights into metabolism, weight loss, and how dietary choices - from high-carb to paleo to carnivore - have shaped his health and outlook. Along the way, we explored how psychology, lifestyle, and even genetic factors influence diet response and metabolic repair. If you're curious about real-world diet experiments, breaking free from calorie myths, or figuring out what works for your body, this video is packed with fascinating research and personal stories. Hit play to join the conversation and learn more about Billy’s unique approach to metabolic health! Links: Substack post about Billy - https://becomeuncivilized.com/p/the-man-who-ate-6000-calories-a-day Billy's Book - https://a.co/d/gqD2QMW Patchwork's DNA Screener: https://patchworkfood.com/dna-screening/ Mac - https://x.com/meta_boli/ Matt - https://x.com/mqsley/ Billy's Patreon - https://www.patreon.com/billycraig CHAPTERS: 00:00 - Intro 00:50 - 6000 Calorie Diet Overview 06:30 - Tracking Calories Pre-Internet 10:41 - Increasing Caloric Intake 12:44 - Weight Gain Discussion 14:58 - Penance in Dieting 17:07 - PhD Research Focus 18:55 - Approaching Metabolic Damage 20:10 - Repairing Your Metabolism 24:05 - Energy Cost of Stress 27:54 - Importance of Consistent Eating 29:35 - Mass Hysteria in Diet Culture 32:17 - Understanding Food Intolerance 37:49 - Tribalism in Diet Choices 40:48 - Building Trust in Groups 42:56 - Stress from Family's Unhealthy Eating44:28 - Raising Kids on Healthy Diet 51:34 - Caloric Needs Explained 58:10 - Questioning Authority in Nutrition 59:20 - Eating Habits and Intelligence 1:02:08 - Patient Compliance in NHS 1:03:54 - Increasing Calories Safely 1:06:21 - Benefits of Having a Coach 1:09:03 - Importance of Listening 1:16:10 - Course Availability Update 1:18:47 - Overview of Your Books 1:22:54 - Consistent Eating Strategies 1:24:05 - Podcast on Consistent Eating 1:26:20 - Thanks and Goodbye 1:26:41 - Disclaimer This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    1 ч. 27 мин.
  2. 08.05.2025

    Transform Your Energy: Tyler’s Bioenergetic Secrets - Tyler Woodward

    Summary We sit down with health coach Tyler Woodward to trace his evolution from a gym‑obsessed teenager to a thoughtful, metabolism‑focused mentor. Tyler candidly shares the missteps of his early dieting days—chasing calories without understanding how metabolism and energy balance truly work—and how those lessons reshaped his approach to nutrition and client care. Together, we unpack the common pitfalls of low‑energy coaching, stressing why adequate caloric intake and hormone balance are non‑negotiable foundations for sustainable progress. Drawing on principles of physiology and Ray Peat–inspired bioenergetics, Tyler highlights the importance of personal experimentation and accountability: thriving isn’t one‑size‑fits‑all. We also dive into real‑world challenges in endurance sports—how altitude, race stress, and recovery demands force us to rethink fueling strategies. Tyler offers practical tips for athletes on optimizing metabolism, tracking progress without getting lost in the numbers, and choosing supplements (or not) with intention, not impulse. By the end of our conversation, you’ll come away with a richer understanding of how modern dietary trends intersect with the body’s innate energy systems—and why tuning into your own physiology is the best roadmap to lasting health and performance. Tyler’s Stuff: https://x.com/Tyler_woodward_ , https://www.instagram.com/tylerwoodward_fit/ Matt’s Stuff: https://x.com/Mqsley , https://becomeuncivilized.com/ Mac’s Stuff: https://x.com/meta_boli , https://metrep.substack.com/ Lose weight with your DNA: https://patchworkfood.com/ Chapters 00:00 Introduction to Tyler Woodward 01:27 Tyler's Early Fitness Journey 05:23 Mistakes in Nutrition and Dieting 09:43 The Role of Physiology in Health Coaching 11:13 Understanding Metabolism and Energy Levels 18:35 Addressing Low Energy States in Clients 23:23 Adjusting Caloric Intake and Activity Levels 30:08 The Impact of Radiation and Health Choices 33:39 Exploring Bioenergetics and Peat's Principles 35:53 Exploring Health Principles through Literature 39:15 The Importance of Personal Experimentation in Health 42:05 Understanding Client Needs and Health Testing 45:51 The Role of Hormones and Inflammation in Weight Management 48:39 Client Profiles and Their Health Goals 49:12 Navigating Caloric Intake and Weight Loss Strategies 52:16 Tracking and Measuring Progress in Health Journeys 56:04 The Supplement Dilemma: Necessity vs. Excess 01:09:51 Backgrounds and Aspirations in Health Coaching 01:11:11 Nutrition Challenges in Endurance Sports 01:14:50 The Impact of Endurance Racing on Recovery 01:18:24 Training Strategies for Endurance Athletes 01:19:51 Altitude Training and Its Effects 01:23:42 Balancing Macronutrients for Optimal Performance 01:26:48 Increasing Metabolism Through Nutrition 01:29:15 Practical Tips for Caloric Surplus 01:35:14 Creative Ways to Enjoy Food While Training Takeaways Tyler's journey began with a desire to get big and muscular. He faced challenges in his fitness journey, including a lack of progress for years. Understanding caloric intake is crucial for energy levels and health. Mistakes in nutrition often stem from high fat and low protein diets. Physiology and chemistry knowledge greatly inform health coaching practices. Low energy states can be addressed by increasing caloric intake gradually. Activity levels should be considered when adjusting caloric intake. Radiation exposure from various sources is often overlooked in health discussions. Bioenergetics principles can guide dietary choices and health improvements. Personal experiences shape one's approach to health and nutrition. The principles of health should be based on personal experimentation. Honesty in health conversations leads to better outcomes. Most people lack a solid foundation in their health journey. Tracking food intake can reveal important insights about metabolism. Hormones are a response to environmental factors, not just isolated issues. Many clients seek sustainable weight loss solutions after failed diets. Caloric intake should be adjusted based on individual needs and goals. Bloating can affect waist measurements, making tracking challenging. Supplements should be used to address specific issues, not as a blanket solution. A solid foundation in health allows for better experimentation with supplements. Nutrition during endurance races often lacks proper fuel options. Recovery strategies are crucial after intense endurance events. Altitude can significantly affect sleep and performance. Balancing macronutrients is essential for optimal athletic performance. Gradual increases in caloric intake can help boost metabolism. Understanding gut health is important for endurance athletes. Creative food choices can enhance enjoyment while training. Monitoring protein intake is vital for muscle recovery. Hydration and electrolyte balance are key during endurance activities. Personal experiences can provide valuable insights into training and nutrition. Keywords health coaching, nutrition, metabolism, energy levels, bioenergetics, fitness journey, dietary mistakes, physiology, caloric intake, health choices, health principles, personal experimentation, client needs, hormones, inflammation, weight management, caloric intake, tracking progress, supplements, health coaching, endurance sports, nutrition, recovery, altitude training, metabolism, caloric surplus, macronutrients, cycling, training strategies, performance This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    1 ч. 37 мин.
  3. 01.05.2025

    How Carnivore Helped Amber Beat Depression 🥩 - Amber O'Hearn

    Amber’s Stuff: https://www.mostly-fat.com/ , https://x.com/KetoCarnivore Matt’s Stuff: https://x.com/Mqsley , https://becomeuncivilized.com/ Mac’s Stuff: https://x.com/meta_boli Lose weight with your DNA: https://patchworkfood.com/ Summary In this episode of the Patchwork Podcast, Amber O'Hearn shares her journey with the carnivore diet, discussing its profound impact on her mental health, weight management, and overall well-being. She delves into the science behind dietary choices, the importance of macronutrient ratios, and the role of supplements like carnitine and vitamin A. The conversation also touches on personal experiences with food tolerance, gut health, and the interplay between genetics and nutrition. Amber emphasizes the need for individuals to listen to their bodies and make informed dietary choices that suit their unique health needs. Takeaways Amber started the carnivore diet in 2009, which helped her manage weight and mental health issues. The carnivore diet was initially called 'zero carb' and focused on eliminating plant sources. Amber experienced significant improvements in mood and weight after adopting the carnivore diet. She emphasizes the importance of eating enough fat to maintain health on a carnivore diet. Many people struggle with under-eating on restrictive diets, which can lead to health issues. Amber discusses the role of fat in satiety and energy levels. She highlights the potential dangers of megadosing vitamins and the importance of balance. Amber shares her experiences with food tolerance and how it has evolved over time. The conversation explores the connection between diet, gut health, and mental well-being. Amber discusses the significance of carnitine and vitamin A in the diet. Chapters 00:00 Amber O'Hearn's Journey Begins 02:46 The Carnivore Diet Explained 05:53 Challenges and Health Issues 09:08 Keto AF: Animal FATs 11:49 Understanding Nutritional Needs 15:08 The Science of Satiety 17:45 Personal Experiences with Diet 21:01 Experimenting with Carbohydrates 23:57 Reflections on Health and Diet 28:59 Understanding Mixed States of Mood Disorders 30:14 The Impact of Diet on Mental Health 32:22 Resilience Through Dietary Changes 34:52 The Connection Between Gut Health and Mood 36:58 Exploring the Role of Vitamin A in Health 44:00 The Debate on Salt in the Carnivore Diet 46:27 Navigating the Complexities of Nutritional Science 58:31 Navigating COVID-19 and Vaccination Choices 01:01:16 Dietary Influences on Health and COVID Severity 01:02:58 Genetic Factors in Nutrition and Health 01:06:09 The Role of Choline and Nutritional Deficiencies 01:10:57 Exploring Supplementation and Its Effects 01:15:32 Carnitine Deficiency and Its Implications 01:21:34 Medical Disclaimer This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    1 ч. 14 мин.
  4. 06.04.2025

    Parkinson's, Microbiome & Food: A Hidden Connection - Martha Carlin

    Summary In this episode of the Patchwork podcast, Martha Carlin, CEO of BiotiQuest, shares her transformative journey from the tech industry to a microbiome & Parkinson's researcher due to her husband getting Parkinson's at an early age. She discusses the critical role of the microbiome in health, particularly in relation to Parkinson's disease, and the disconnect between medicine, science research and microbiome research. Martha highlights the impact of glyphosate on health, the interconnectedness of food systems, and the importance of probiotics. She also introduces her product, Sugar Shift, which aims to help regulate sugar cravings and improve metabolic health. Chapters 00:00 Martha's Journey into Microbiome Research 03:45 The Disconnect Between Medicine and Microbiome 09:40 Glyphosate and Food Contamination Challenges 15:15 The Role of Microbiome in Parkinson's Disease 24:10 The Impact of Environmental Toxins on Health 25:37 Genetics and Parkinson's Disease 26:36 Endotoxins and Their Role in Disease 28:37 Endurance Sports and Gut Health 30:25 Metabolic Flexibility and Inflammation 32:05 Probiotics: Necessity or Marketing? 33:38 The Science of Probiotics 37:33 Sugar Shift: A New Approach to Gut Health 43:38 Interconnectedness in Health and Medicine Keywords microbiome, probiotics, health, Parkinson's disease, glyphosate, nutrition, gut health, endotoxins, Sugar Shift, metabolic health This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    49 мин.
  5. 01.04.2025

    How I Reversed 10 Years of Health Struggles 🚀 - Just Another Peater

    Links Just Another Peater’s Links: https://linktr.ee/justanotherpeater Lose weight with your DNA: https://patchworkfood.com/ Summary In this episode of the Patchwork Podcast, Mac engages with Just Another Peater, who shares her transformative journey through health struggles, traditional advice, and the discovery of alternative methodologies. The conversation delves into the impact of hormones, the importance of nutrition, and the individual variations in dietary needs. Peater discusses her experiences with hypothalamic amenorrhea, the role of progesterone, and the significance of intuitive eating. The episode emphasizes the need for personalized health approaches and the challenges of navigating dietary advice in a world filled with conflicting information. In this conversation, the speakers delve into various aspects of health, including metabolism, thyroid health, dietary choices, and the impact of social media on personal journeys. They discuss the importance of understanding hormonal balance, the role of supplements, and the complexities of intuitive eating. The conversation also touches on the significance of testing and biomarkers in health management, as well as the effects of birth control on hormonal health. Takeaways Health journeys are often filled with struggles and discoveries. Traditional health advice may not work for everyone. Hormones play a crucial role in overall health and well-being. Dietary changes can lead to significant improvements in health. Individual variation is key in determining dietary needs. Intuitive eating can help in understanding personal health better. Sunlight and vitamin D are important for health, but moderation is key. Tracking food intake can be beneficial but is not always necessary. Understanding the impact of estrogen and progesterone is vital for women. Personal experiences can guide others in their health journeys. Struggles with metabolism can be linked to thyroid health. Social media can serve as a platform for sharing personal health journeys. Dietary choices significantly impact overall health and well-being. Understanding hormonal balance is crucial for managing health issues. Supplements can play a role in addressing specific health concerns. Intuitive eating can be complex and influenced by cravings and dietary habits. Ray Peat's dietary principles offer a unique perspective on nutrition. Energy and structure are interdependent in maintaining health. Birth control can have significant effects on hormonal balance and health. Testing and biomarkers provide valuable insights into personal health. Chapters 00:00 Introduction to Health Struggles 02:42 The Impact of Nutrition on Health 05:35 The Role of Diet in Hormonal Balance 08:21 Navigating Health Challenges Post-COVID 11:15 Finding Balance in Nutrition 14:06 Current Health and Eating Habits 17:52 Navigating Thyroid Health and Nutrition 19:41 The Journey of Sharing Knowledge on Social Media 21:26 Balancing Music, Education, and Personal Growth 22:15 Exploring Dietary Practices and Intuitive Eating 33:41 Understanding the Bioenergetic Approach to Nutrition 37:01 Navigating Dietary Challenges and Intolerances 37:32 Understanding Energy Production and Nutritional Needs 39:03 The Role of Hormones in Health 39:47 Exploring the Impact of Birth Control 42:23 The Importance of Testing and Biomarkers 43:34 Experimenting with Hormones and Supplements 46:14 Regulatory Challenges and Access to Supplements 47:40 The Value of Personalized Health Insights 49:36 Navigating Health and Hormones 52:16 Genetic Insights and Dietary Choices 55:02 The Role of Carbohydrates in Weight Management 57:53 Individual Variations in Diet and Nutrition 01:00:47 Understanding Hormonal Balance and Health 01:03:27 Sunlight, Vitamin D, and Personal Needs 01:06:10 Medical Disclaimer Keywords health, nutrition, hormones, diet, personal journey, wellness, Ray Peat, estrogen, progesterone, individual variation, metabolism, thyroid health, social media, dietary choices, hormonal balance, supplements, intuitive eating, Ray Peat, energy structure, birth control, biomarkers This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    1 ч. 7 мин.
  6. From 12-Year-Old Dieter to Ray Peat Advocate 🌟 - Berry Fairy

    27.03.2025

    From 12-Year-Old Dieter to Ray Peat Advocate 🌟 - Berry Fairy

    Links Berry Fairy’s X account: http://x.com/galaxynymph/ Insta: https://www.instagram.com/peaterpan99/ Lose weight with your DNA: https://patchworkfood.com/ Summary In this episode of the Patchwork Podcast, host Mac interviews Berry Fairy, a young health enthusiast who shares her unique journey into health and wellness. Starting at a young age, Berry navigated through various health trends, including a plant-based diet, before discovering the Ray Peat approach. The conversation explores her early experiments with health, the impact of social media on health perceptions, family dynamics, and the importance of curiosity in exploring health topics. Berry discusses her dietary changes, the role of supplements, and her creative outlets through social media, all while emphasizing the significance of intuitive eating and body positivity. Takeaways Berry started her health journey at a young age, experimenting with various diets. She initially followed a plant-based diet influenced by her mother's beliefs. Discovering Ray Peat's approach changed her perspective on nutrition. Social media, especially Twitter, played a significant role in her health education. Berry emphasizes the importance of family support in her health experiments. Curiosity and self-experimentation have been key to her learning process. She advocates for intuitive eating over strict dietary rules. The influence of TikTok on health trends is concerning for younger generations. Berry believes that many teens have unrealized potential due to social media echo chambers. Chapters 00:00 Introduction to Berry Fairy's Health Journey 02:48 Early Health Experiments and Discoveries 05:25 Transitioning to Ray Peat School and New Perspectives 08:06 The Role of Family and Social Dynamics 11:03 Navigating School Life and Peer Reactions 13:55 The Impact of Dietary Changes on Energy and Well-being 16:40 Cooking and Eating Habits at Home 19:29 Reflections on Body Image and Health 22:18 Concluding Thoughts on Health and Nutrition 28:51 The Art of Articulation and Calmness 30:01 Understanding ADHD and Energy Regulation 31:13 Intuitive Eating and Weight Loss 32:09 Building a Twitter Following and Creative Outlets 34:05 The Role of Supplements in Mental Clarity 37:56 Weight Loss Caramel 41:21 The Impact of Technology on Social Interaction 42:27 Echo Chambers and the Potential of Youth 45:55 Navigating Social Media as a Young Creator 47:41 The Importance of Curiosity in Adolescence 51:18 Medical Disclaimer Keywords health journey, Ray Peat, teen health, social media influence, intuitive eating, family support, dietary changes, supplements, body image, creative outlets This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    52 мин.
  7. 15.03.2025

    Testosterone Myths: What You’re Doing Wrong - Hans Amato

    In this episode, we delve into the complexities of testosterone, its effects on the body, and the various factors influencing testosterone levels. We discuss the importance of nutrition, the role of stress hormones, and the potential pitfalls of relying solely on testosterone replacement therapy (TRT). Through case studies, we explore individual experiences with testosterone and muscle development, emphasizing the need for a holistic approach to health that includes addressing nutritional deficiencies and understanding the body's energy systems, and how often it isn’t testosterone, or how testosterone levels are a ‘side effect’ of becoming healthier in general. They share personal experiences regarding health journeys, the significance of testing for gut health, and the challenges of weight management. The discussion also touches on the debate over what it means to be 'natty' in the fitness community. Links Han’s Free Testosterone Book: https://testonation.gumroad.com/l/testosteronebook * TestoTribe Community & Consults * X: https://x.com/HansAmato * Website: https://testonation.com/ Matt: https://x.com/mqsley/ Mac: https://x.com/meta_boli/ Takeaways * Testosterone is not a magic bullet for health issues. * Nutritional deficiencies can significantly impact testosterone levels. * Stress hormones can lead to a catabolic crisis. * Recovery length can indicate hormonal balance issues. * Animal foods provide essential peptides for health. * TRT may not resolve underlying health problems. * Understanding individual metabolism is crucial for fitness. * A holistic approach to health is necessary for optimal performance. * Experimentation is key to finding what works for your body. * Gut health plays a significant role in hormone production. Choline plays a significant role in weight loss and liver health. * Low testosterone can indicate broader health issues rather than being a standalone problem. * Sleep and sunlight are crucial for overall health and hormone balance. * Vitamin B2 is often overlooked but essential for energy metabolism. * Testing for gut health is vital to address underlying issues. * Weight management can be complicated by metabolic health and hormonal balance. * TRT can be beneficial but should be approached with caution and proper health optimization. * The definition of being 'natty' is subjective and varies among individuals. * Personal health journeys often involve trial and error with various supplements and diets. * Maintaining a healthy lifestyle is a long-term commitment that requires ongoing adjustments. Chapters 00:00 Understanding Testosterone and Its Impact 02:36 Personal Experiences with Testosterone 05:32 Case Study: Upper Body Strength Challenges 08:19 The Role of Recovery and Hormones 11:10 The Myths of Testosterone Replacement Therapy 13:51 The Connection Between Gut Health and Testosterone 16:53 Exploring Thyroid and Testosterone Interactions 19:36 The Importance of Nutritional Deficiencies 22:20 Case Study: Overcoming Muscle Gain Plateaus 25:16 The Catabolic Crisis Explained 34:00 Understanding Catabolic Crisis 36:05 The Role of Mitochondria in Metabolism 38:25 Genetic Testing and Nutritional Needs 40:43 Macronutrient Flexibility and Nutritional Deficiencies 42:32 The Impact of Diet on Hormonal Health 45:34 The Importance of Micronutrients 48:11 Addressing Low Testosterone: A Holistic Approach 50:49 Sunlight, UVB and Vitamin D 54:48 Han's Catabolic Crisis Story 58:57 Understanding Gut Health and SIBO 01:01:28 Matt's Case 01:06:34 Navigating Hormonal Health and Testing 01:10:27 The Challenges of Fat Loss and Muscle Gain 01:14:56 Exploring Hormonal Ratios and Their Effects 01:17:09 The Debate on Being 'Natty' in Fitness 01:22:53 Sustainability and Health in Diet Choices 01:27:06 Introduction and Disclaimer 01:27:07 Exploring Unique Health Experiments This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    1 ч. 28 мин.
  8. 13.03.2025

    The Diet That Transformed My Life Forever 💪 - Gator Dad Steve

    Steve shares his transformative journey from dealing with severe back injuries and weight gain to adopting a strict carnivore diet, which he credits for significant health improvements. He discusses the challenges of weight loss, the importance of discipline in maintaining a healthy lifestyle, and the complexities of nutrition, including the impact of food sensitivities and hormonal health. The discussion also touches on broader topics such as the medical system's approach to diet and health, the influence of the environment on eating habits, and the controversial perspectives on ADHD and nutrition. The conversation also touches on inflammation, gut health, metabolism, and the influence of genetics on dietary needs. Steve’s X: https://x.com/gatordadsteve Mac: https://x.com/meta_boli/ Matt: https://x.com/mqsley/ Takeaways * Steve's journey began with serious back injuries that led to weight gain. * He adopted the lion diet, consisting solely of meat, which helped him lose weight. * Discipline is crucial in maintaining a healthy lifestyle and diet. * Steve tracks everything he eats, emphasizing the importance of knowing food intake. * He believes that many health issues, including ADHD, are linked to diet. * The medical system often fails to provide adequate dietary guidance for health issues. * Steve's experience with testosterone therapy highlights the complexities of hormonal health. * He discovered food sensitivities that impacted his health, particularly with nightshades. * The conversation critiques the oversimplification of diets like carnivore and the need for balance. * Steve emphasizes that calories from different sources affect the body differently. Switching from beef to fish can affect testosterone levels. * Peptide differences in food may influence bodily responses. * Real food is often preferred over supplements. * Bone broth and marrow can be nutritious alternatives. * High protein diets may require additional support to maintain metabolism. * Tomatoes can trigger adverse reactions in some individuals. * Organic acid tests can provide insights into metabolic health. * Gut health is crucial for overall well-being and hormone production. * Genetic factors can influence dietary responses and needs. * Fasting can lead to unexpected weight loss without calorie restriction. Chapters 00:00 Introduction to Steve's Journey 02:55 Overcoming Health Challenges 05:36 The Lion Diet Experience 08:23 Struggles with Bulking and Cutting 11:17 The Role of Testosterone in Fitness 14:04 Discipline and Food Choices 16:59 The Impact of Processed Foods on Health 19:51 Reflections on ADHD and Nutrition 22:48 Critique of the Medical System 25:22 Navigating Dietary Challenges in Diabetes Management 28:27 The Impact of Diet on Thyroid Function 32:12 Understanding Carnivore Diet and Its Implications 37:02 The Complexities of Caloric Intake and Metabolism 42:45 Exploring Food Sensitivities and Gut Health 49:40 The Role of Inflammation in Health and Nutrition 50:56 Understanding Gut Health and Dysfunction 52:36 Exploring Cardiovascular Health and Testing 54:04 Navigating Weight Management and Body Composition 56:03 The Role of Hormones in Health 58:37 Dietary Preferences and Nutritional Strategies 01:01:28 The Impact of Protein and Fasting on Hunger 01:04:26 The Relationship Between Food Choices and Body Response 01:07:01 Genetics and Personalized Nutrition 01:08:34 Reflections on Health and Resilience 01:15:38 Introduction and Disclaimer 01:15:39 Exploring Unique Health Experiments This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    1 ч. 16 мин.
  9. Hormone Hacks: My Journey with Testosterone Therapy - Greg Mushen

    18.02.2025

    Hormone Hacks: My Journey with Testosterone Therapy - Greg Mushen

    In this episode, we talk with Greg about his experience of testosterone replacement therapy and why he does it. He is very knowledgeable in this subject, and he loves to dive deep into the mechanisms, to the point where somebody asked him if they should write if they would write a book with him. There are many ways to do this incorrectly, so listen to this podcast to learn what you should know before potentially doing it yourself. We also talk about some exciting things about female hormone replacement therapy, something you probably haven't heard before. Takeaways (AI Summary) * Testosterone levels can fluctuate seasonally, impacting mood and energy. * TRT is often misunderstood and associated with negative stereotypes. * There is a significant difference between TRT and anabolic steroid use. * Female hormone replacement therapy is more complex than male. * Lifestyle factors like sleep and nutrition greatly affect hormone levels. * Regular blood work is essential for monitoring hormone levels. * Understanding the hormone cascade is crucial for hormone health. * Optimized testosterone can lead to improved physical and mental health. * There are risks associated with TRT that need to be managed. * The benefits of optimized testosterone include better mood, libido, and muscle mass. * Testosterone can convert to estrogen, affecting mood and health. It is something to watch out for. * Frequent smaller injections may help manage estrogen conversion. * Different delivery methods for testosterone have varying effects. * Mood issues can arise from high testosterone and estrogen levels. * TRT can improve body composition and mental health. * Diet impacts lipid profiles and overall hormonal health. * Anabolic steroids are often used without sufficient research. * Finding a knowledgeable provider is crucial for safe TRT. * Monitoring hormone levels is essential for effective treatment. * Stigma around TRT can hinder access to necessary care. Chapters (AI Made) 00:00 Introduction to Hormone Optimization 01:18 Greg's Journey with Testosterone 04:21 Understanding Seasonal Affective Disorder and Testosterone 06:55 Myths and Stigmas Surrounding TRT 09:15 Research Gaps in Hormone Replacement Therapy 11:18 Complexities of Female Hormone Replacement 14:05 Innovations in Women's Hormone Therapy 16:27 The Importance of Comprehensive Testing 19:24 Concerns and Risks of TRT 22:16 Navigating Fertility and Hormone Therapy 24:54 Understanding Hormonal Interactions and Lifestyle Factors 29:25 Nutritional Factors Influencing Hormone Production 30:39 The Importance of Sleep for Hormonal Health 32:51 Personal Experiences with Hormonal Imbalance 35:43 The Role of Vitamin D and Nutrient Deficiencies 37:36 The Dangers of Aggressive Dieting and Nutritional Deficiencies 38:26 Understanding Testosterone and Its Effects 41:09 Benefits of Optimal Testosterone Levels 44:41 The Science of Testosterone Administration 47:09 Risks and Considerations of Testosterone Therapy 51:17 The Broader Health Implications of Testosterone 52:49 Dietary Considerations for Hormonal Health 54:56 Exploring Anabolic Steroids and Their Effects 57:00 Understanding Testosterone Therapy 01:00:40 Navigating the Healthcare System for TRT 01:04:24 Dosing and Individual Responses to Testosterone 01:08:09 Testing and Monitoring Hormone Levels 01:11:56 Interpreting Hormone Ranges and Their Implications 01:18:56 Medical Disclaimer This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    1 ч. 19 мин.
  10. Can You Hack IQ? Anabology's Bold Experiment 🧠 - Anabology

    22.01.2025

    Can You Hack IQ? Anabology's Bold Experiment 🧠 - Anabology

    In this episode of the Patchwork podcast, Anabology, an anonymous scientist and PhD dropout, discusses his unconventional perspectives on diet, metabolism, and intelligence. The conversation explores his honey diet, theories of IQ, sensory processing, and potential interventions for cognitive enhancement, including neurofeedback and TMS. The hosts and Anabology delve into the complexities of intelligence, the impact of sensory data on brain function, and the challenges of researching these topics in a politically sensitive environment. Links * Anabology’s X account: https://x.com/anabology * Anabology’s website: https://anabology.com/ * Mahyar’s X account: https://x.com/meta_boli * Matt’s X account: https://x.com/mqsley/ * Lose weight with DNA-customized diet plans from Patchwork: https://patchworkfood.com Takeaways Anabology dropped out of his PhD to pursue a biotech company. The honey diet is an unconventional approach to nutrition. IQ is often viewed as a fixed trait, but there are ways to potentially improve it. Sensory processing issues can affect cognitive performance. Neurofeedback aims to optimize brain function by targeting specific EEG states. Psychedelics may help in re-encoding traumatic memories. Improving metabolic health can have a positive impact on cognitive abilities. The brain functions as a prediction system, integrating sensory data and expectations. Research on intelligence is often politically sensitive and underfunded. Interventions like TMS may offer new avenues for cognitive enhancement. Chapters 00:00 Introduction 02:44 Exploring Neurofeedback and IQ Improvement 09:14 Theories of Intelligence and Cognitive Processing 15:03 Sensory Sensitivity and Neurodiversity 21:00 Challenging the Fixed Nature of IQ 26:58 Innovative Approaches to Enhance Intelligence 30:38 Exploring IQ Testing and Human Variance 32:33 Blinking LEDs 34:10 Surfing Uncertainty Book 35:47 Insights on the Honey Diet: Theories and Experiences 35:47 Outro This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

    38 мин.
  11. The Honey Diet: Unlocking Metabolic Secrets 🍯 - Anabology

    22.01.2025

    The Honey Diet: Unlocking Metabolic Secrets 🍯 - Anabology

    In this episode of the Patchwork Podcast, host Mahyar McDonald engages with Anabology, an anonymous scientist and PhD dropout, to discuss the intriguing concept of the honey diet. The conversation delves into the mechanisms behind the diet, particularly the role of FGF21 in metabolism, and shares personal experiences and insights from both the host and guest. They explore the implications of genetic testing for personalized nutrition, ethical considerations in longevity research, and the potential for a diet experience database to help others navigate their dietary journeys. We also talked about how Anabology recently lost weight with UV light and what research study he would try to complete if he had unlimited budget and power. Links * Anabology’s X account: https://x.com/anabology * Anabology’s website: https://anabology.com/ * Mahyar’s X account: https://x.com/meta_boli * Matt’s X account: https://x.com/mqsley/ * Lose weight with DNA-customized diet plans from Patchwork: https://patchworkfood.com Takeaways * The honey diet leverages FGF21 to enhance metabolism. * Personal experiences with the honey diet vary significantly. * Thiamine supplementation can support high sugar diets. * Genetic testing may provide insights into dietary needs. * Ethical considerations are crucial in longevity research. * The honey diet can be adapted for weight maintenance or loss. * Dietary experiments should be documented for better understanding. * Metabolic responses to diets can differ based on genetics. * Cold tolerance may improve with certain dietary approaches. * A centralized database for dietary experiences could be beneficial. Chapters 00:00 Intro 00:51 The Honey Diet 12:10 Choline, FGF21, and Metabolic Health 28:55 Cold Tolerance and Metabolic Adaptation 31:02 Dietary Experiments: Potatoes vs. Honey 31:57 Anabolic vs. Catabolic States in Weight Loss 34:27 The Role of FGF21 in Metabolism 35:07 Data Sharing and Diet Experience 36:11 Fasting Periods and Protein Intake 36:55 Blood Sugar Responses and Exercise 38:31 Genetic Factors in Diet Response 40:12 The Impact of Sunlight on Metabolism 51:15 Supplements for Optimizing Sugar Diets 52:13 Anabology's Spicy Wishlist Study 59:01 Outro This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit patchworkfood.substack.com

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We talk about esoteric and cutting-edge health research with many guests that fixes people's health problems via nutrition, DNA analysis and more while being as low effort as it was in the 1950s. patchworkfood.substack.com