Primary Care Pod Dr. Mark List

Fun, quick episode this week. 
 
https://pubmed.ncbi.nlm.nih.gov/33934725/
 
Non-fatal senior pickleball and tennis-related injuries treated in United States emergency departments, 2010-2019
 
Harold Weiss 1, Jacob Dougherty 2, Charles DiMaggio 3

Today's episode is a very complicated topic without clear cut benefits. Expert opinions and modeling data to address a dangerous and serious topic. Let's look at 2 sources: a new study from the Annals of Internal Medicine and an expert opinion from Uptodate.
 
https://www.uptodate.com/contents/selecting-adult-patients-with-lower-extremity-deep-venous-thrombosis-and-pulmonary-embolism-for-indefinite-anticoagulation?search=unprovoked%20dvt&sectionRank=1&usage_type=default&anchor=H648618&source=machineLearning&selectedTitle=1~150&display_rank=1#H648618
 
vs.
 
https://pubmed.ncbi.nlm.nih.gov/37364263/
Indefinite Anticoagulant Therapy for First Unprovoked Venous Thromboembolism : A Cost-Effectiveness Study
Faizan Khan 1, Doug Coyle 2, Kednapa Thavorn 3, Sasha van Katwyk 4, Tobias Tritschler 5, Brian Hutton 6, Grégoire Le Gal 7, Marc A Rodger 8, Dean A Fergusson 9

Time restricted eating vs. caloric restriction. Is there a winner in this 1:1:1 12-month trial from Chicago?
 
https://pubmed.ncbi.nlm.nih.gov/37364268/
Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population : A Randomized Controlled Trial


Shuhao Lin 1, Sofia Cienfuegos 1, Mark Ezpeleta 1, Kelsey Gabel 1, Vasiliki Pavlou 1, Andrea Mulas 1, Kaitie Chakos 1, Mara McStay 1, Jackie Wu 1, Lisa Tussing-Humphreys 2, Shaina J Alexandria 3, Julienne Sanchez 4, Terry Unterman 5, Krista A Varady 1

Talking about 2 studies released last month:
 
1. Giving it to 3rd trimester moms and seeing what happens in newborns:
https://pubmed.ncbi.nlm.nih.gov/37018474/
 
2. Giving it to 60+ yo adults and seeing what happens:
https://pubmed.ncbi.nlm.nih.gov/37018468/
 
What happens when I review these? Listen to find out!
 
Helpful table (Not sure if this will reproduce well or not):
 
NNT
Vaccine Efficacy
Severe LRI
 
 
first 90 d
142
81%
In 6 mo
75
69%
ADULTS
1428
85%
 
 
 
non-severe LRI
 
 
first 90 d
111
57
6mo
55
51%
ADULTS
769
66%
 
 
 
Any URI
 
 
ADULTS
500
62%
 

Hey everyone, on today's episode we are talking about a recent JAMA article on Heterogeneity in Blood Pressure Response to various blood pressure medicines and the idea of individualizing antihypertensive algorithms.
 
https://jamanetwork.com/journals/jama/article-abstract/2803518

Today's episode we look at a study of 60+ year olds who have poorly controlled depression.  Is it better to add on medications? Switch medications? Does it matter? 
 
Study link:
https://pubmed.ncbi.nlm.nih.gov/36867173/