Rx for Biotech

Podcast Host Chris Leidli

"Rx for Biotech" is a healthcare education podcast dedicated to helping patients, caregivers, and healthcare professionals understand the rapidly evolving world of advanced therapies - and how patients can access them. From cell therapies and gene therapies to radiopharmaceuticals, immunotherapies, and next-generation treatments for cancer and autoimmune disease, this channel bridges the gap between breakthrough science and real-world patient care. Hosted by Chris Leidli, founder of Genoplex and longtime host of the Rx for Biotech podcast, each episode features conversations with: • Biotech and pharmaceutical CEOs • Physician leaders and researchers • AI and tech leaders building tools to improve healthcare access • Innovators building the next generation of personalized therapies About Therapy4me.ai Therapy4me.ai is a consumer education and care-navigation platform designed to help patients find and connect with specialists at treatment centers offering personalized medicines and advanced therapies. Learn more: https://www.therapy4me.ai To learn more about Genoplex, please visit https://www.genoplex.ai

  1. 4d ago

    Can Stem Cell Therapy Heal Chronic Back Pain? The Future of Regenerative Medicine

    Can stem cell therapy help repair damaged spinal discs instead of simply masking pain? Millions of people suffer from chronic low back pain and degenerative disc disease, yet today's standard treatments often focus on symptom management through pain medications, steroid injections, or invasive surgery. But what if regenerative medicine could change that? In this episode of Rx for Biotech, host Chris Leidli sits down with Lance Alstodt, CEO of BioRestorative Therapies, to explore how the company is developing next-generation regenerative medicine platforms designed to restore function—not just relieve symptoms. Lance discusses BioRestorative's lead clinical program, BRTX-100, an investigational autologous stem cell therapy currently in Phase 2 clinical development for chronic lumbar disc disease. The conversation explores how stem cells are expanded using the company's proprietary hypoxic manufacturing process before being injected directly into damaged spinal discs in an effort to promote tissue repair. The discussion also looks beyond spine health to BioRestorative's ThermoStem® platform, which is investigating the potential of brown adipose (brown fat) stem cells to improve metabolic health and complement GLP-1 weight-loss therapies. Finally, Lance explains how the company's expertise in stem cells and exosome biology is also being applied to next-generation skincare and regenerative aesthetics. In this episode you'll learn: • Why chronic low back pain remains one of healthcare's largest unmet needs • How regenerative medicine differs from traditional pain management • The science behind BRTX-100 and autologous stem cell therapy • Why BioRestorative uses proprietary hypoxic cell expansion • Current Phase 2 clinical trial progress and safety observations • The future of regenerative medicine for orthopedic diseases • How brown fat stem cells could complement GLP-1 therapies • What exosomes are—and why not all exosomes are created equal • The difference between FDA-regulated cell therapies and many commercial regenerative medicine clinics • BioRestorative's long-term vision for restoring function instead of simply managing symptoms Whether you're a patient living with chronic back pain, a healthcare professional, an investor, or simply interested in the future of regenerative medicine, this episode provides an inside look at one of the most exciting areas of biotechnology.

    Can Stem Cell Therapy Heal Chronic Back Pain? The Future of Regenerative Medicine

  2. Jul 7

    Part 2: What Is Radioligand Therapy? A New Precision Treatment for Cancer Explained

    What if cancer treatment could find and destroy cancer cells with extraordinary precision while minimizing damage to healthy tissue? In Part 2 of this special Rx for Biotech series, Dr. Babak Saboury and Dr. Eliot Siegel from United Theranostics explain radioligand therapy (RLT), one of the fastest-growing areas in precision medicine and cancer treatment. Radioligand therapies combine advanced imaging and targeted radiation to identify, track, and treat cancer cells throughout the body. This emerging field, known as theranostics, allows physicians to "see what they treat and treat what they see." In this episode, you'll learn: • What radioligand therapy (RLT) is • How theranostics works • The difference between traditional radiation and targeted radiopharmaceutical therapy • How imaging helps personalize treatment • Why prostate cancer and neuroendocrine tumor patients are benefiting today • What patients can expect during treatment • Common side effects and safety considerations If you or someone you love has been diagnosed with cancer, this conversation is a good educational primer to one of the most promising advances in oncology. Subscribe for more patient-focused conversations on cancer treatment, precision medicine, immunotherapy, cell therapy, and healthcare innovation. #CancerTreatment #RadioligandTherapy #Theranostics #ProstateCancer #NeuroendocrineTumors #PrecisionMedicine

    Part 2: What Is Radioligand Therapy? A New Precision Treatment for Cancer Explained

  3. Jun 30

    Part 1: The Radiopharmaceutical Launch Playbook: What Pharma Must Get Right Beyond the Drug

    What does it really take to successfully launch a radiopharmaceutical? In Part 1 of this special roundtable “Rx for Biotech” podcast series, Chris Leidli met with Dr. Babak Saboury and Dr. Eliot Siegel, founders of United Theranostics and nationally recognized leaders in nuclear oncology, to discuss one of the biggest challenges facing the radiopharmaceutical industry today: building the infrastructure to expand patient access to these innovative medicines. While radioligand therapies (RLTs) and theranostics are generating unprecedented excitement in oncology, many pharmaceutical companies underestimate the complexity of delivering these therapies to patients. In this episode, we discuss: • Why only a small percentage of eligible patients currently receive radioligand therapy • Site readiness, staffing, and infrastructure challenges • Why traditional pharmaceutical launch models often fail in radiopharmaceuticals • Building sustainable access for patients • What pharmaceutical companies should understand before launching an RLT This conversation offers a front-line perspective on what it will take to scale the future of radiopharmaceutical medicine. 🎧 Subscribe for more conversations on radiopharmaceuticals, precision medicine, oncology, targeted therapies, and advanced therapies. #Radiopharmaceuticals #RadioligandTherapy #Theranostics #PrecisionMedicine #Oncology #NuclearMedicine #Pharma #Biotech #HealthcareInnovation #RxForBiotech

    Part 1: The Radiopharmaceutical Launch Playbook: What Pharma Must Get Right Beyond the Drug

  4. Jun 16

    Why Fertility Care Needs to Change - And How Technology Can Help

    What if AI could help women better understand their bodies and take control of their health before problems become crises? In this episode of #RxforBiotech, host Chris Leidli sits down with Kirsten Karchmer, Founder and CEO of Conceivable, to discuss the future of women's health, fertility, hormone health, and personalized medicine. After helping more than 10,000 women improve their fertility and reproductive health over the past 25 years, Kirsten is now building an AI-powered operating system designed to help women understand the root causes of health challenges rather than simply treating symptoms. From fertility and PCOS to fatigue, hormone imbalances, perimenopause, and menopause, Conceivable combines artificial intelligence, wearable data, lifestyle insights, and personalized coaching to help women make informed decisions about their health. In this episode, we discuss: • Why so many women feel dismissed by the healthcare system • The future of AI in women's health • Fertility treatment and reproductive health • Personalized medicine and hormone optimization • The role of wearables, biomarkers, and health data • Menopause, perimenopause, and healthy aging • How AI can help women become advocates for their own health • Why understanding the root cause matters more than treating symptoms Whether you're trying to conceive, navigating hormone changes, managing a chronic condition, or simply interested in the future of healthcare, this conversation offers an inspiring look at how technology can empower women throughout every stage of life. 🎧 Subscribe for more conversations on healthcare innovation, precision medicine, AI, women's health, and advanced therapies.

    Why Fertility Care Needs to Change - And How Technology Can Help

  5. May 30

    The Future of Multiple Sclerosis Treatment: New Hope for MS Patients | Jason Tardio, Immunic

    What if the future of multiple sclerosis treatment could go beyond suppressing inflammation - and actually help protect the brain? In this episode of Rx for Biotech, host Chris Leidli sits down with Jason Tardio, President & COO of Immunic Therapeutics, to discuss the evolving future of treatment for Multiple Sclerosis (MS), one of the most complex autoimmune and neurodegenerative diseases affecting millions worldwide. Jason shares his deep experience leading major MS franchises at Biogen and Novartis, explains how MS attacks the brain and spinal cord, and breaks down why many current therapies focus primarily on inflammation but may not fully address the neurodegeneration driving long-term disability. The conversation also explores Immunic’s lead investigational therapy, vidofludimus calcium, an oral once-daily treatment being studied in Phase 3 clinical trials for relapsing multiple sclerosis. The company believes the therapy may offer a unique dual approach by targeting both neuroinflammation and neurodegeneration. Topics discussed include: • What causes multiple sclerosis • Early symptoms and diagnosis of MS • How MRI imaging transformed MS care • Why MS remains difficult to treat • The difference between inflammation and neurodegeneration • Oral therapies vs infusions and injectables • Progressive multiple sclerosis and unmet patient needs • The future of neuroscience, immunotherapy, and personalized medicine For patients, caregivers, healthcare providers, and anyone interested in the future of neurology and autoimmune disease treatment, this episode offers an accessible and hopeful look at where MS care may be headed next.

    The Future of Multiple Sclerosis Treatment: New Hope for MS Patients | Jason Tardio, Immunic

  6. May 19

    What If Your Own Cells Could Cure Cancer? CAR-T Therapy Explained

    What if your own immune cells could be engineered to fight and even cure cancer? In this episode of Rx for Biotech, host Chris Leidli sits down with Navneet Majhail, MD, a leading expert in blood cancers, bone marrow transplants, and CAR-T cell therapy, to break down one of the most powerful innovations in modern medicine: CAR-T therapy. CAR-T therapy is a form of immunotherapy that uses a patient’s own T cells - engineered in a lab - to recognize and destroy cancer. It has already transformed outcomes for patients with leukemia, lymphoma, and multiple myeloma, offering hope where few options previously existed. But despite its promise, many eligible patients still don’t receive CAR-T therapy due to barriers like access, geography, insurance, and care coordination. In this conversation, Dr. Majhail explains: • What CAR-T cell therapy is and how it works • Why access to treatment remains a major challenge • The role of bone marrow transplant and cellular therapy networks • How care is shifting closer to home through community-based treatment models • The importance of caregivers and support systems during treatment • What the future holds for CAR-T in solid tumors, autoimmune diseases, and beyond This episode is a must-watch for patients, caregivers, and anyone interested in the future of personalized cancer treatment, immunotherapy, and advanced therapies

    What If Your Own Cells Could Cure Cancer? CAR-T Therapy Explained

  7. May 7

    The Future of Brain Cancer Care: Combining Diagnostics and Targeted Radiation Therapy

    Why is brain cancer so hard to detect and treat - and what if we could change that? In this episode of Rx for Biotech, host Chris Leidli sits down with Marc Hedrick, CEO of Plus Therapeutics, and Russell Bradley, General Manager of CNSide Diagnostics, to explore a new, integrated approach to treating some of the most challenging cancers in medicine: central nervous system (CNS) cancers, including glioblastoma and leptomeningeal metastases. Brain and CNS cancers are among the most difficult to treat because of the blood-brain barrier, which prevents most drugs from reaching tumors. In fact, only a small percentage of therapies can effectively cross into the brain—limiting treatment options and outcomes. Plus Therapeutics is tackling this problem with a novel approach using targeted radiation therapy delivered directly to tumors, bypassing the blood-brain barrier. Their lead program uses a radioactive isotope (rhenium-186) delivered via nanoliposomes, allowing high doses of radiation to reach the tumor while minimizing damage to the rest of the body. At the same time, CNSide Diagnostics is helping physicians detect cancer earlier and monitor treatment response using an advanced cerebrospinal fluid (CSF) diagnostic test. This highly sensitive test can identify even small numbers of tumor cells—helping doctors make faster, more informed treatment decisions. Together, this combination of diagnostics + therapeutics + data represents a new model for precision oncology and personalized cancer care. In this episode, we discuss: • Why brain cancer is so difficult to treat • The role of the blood-brain barrier in limiting therapies • How targeted radiation therapy can improve outcomes • The importance of early detection and diagnostics • How monitoring tumor cells can guide treatment decisions • The future of integrated cancer care (theranostics) This conversation offers a powerful look at how innovation in both treatment and diagnostics could help improve survival and quality of life for patients with some of the most aggressive cancers.

    The Future of Brain Cancer Care: Combining Diagnostics and Targeted Radiation Therapy

  8. Apr 28

    How Ossium Health is Changing Stem Cell Therapy and Regenerative Medicine

    What if you could get a Transplant and Reset your Immune System in less than 48 Hours? In this episode of Rx for Biotech, host Chris Leidli sits down with Kevin Caldwell, CEO of Ossium Health, to explore how bone marrow transplants, cell therapy, and bioengineered immune systems are transforming the future of medicine. Ossium Health is building a first-of-its-kind bone marrow banking platform, using donor-derived cells to make life-saving treatments available on demand. Traditionally, patients can wait months to find a donor match - time many simply don’t have. Ossium is changing that by enabling transplants in as little as 48 hours, dramatically improving access to care. In this conversation, Kevin explains how bone marrow transplants work, why they are one of the most powerful tools in modern medicine, and how replacing a patient’s blood and immune system can treat diseases like blood cancers and immune disorders. We also dive into: • Why most eligible patients never receive a bone marrow transplant • How off-the-shelf cell therapy could scale life-saving treatments • The role of the immune system in preventing disease and cancer • How donor-derived cells could unlock the future of regenerative medicine and longevity • Why improving immune health may be one of the most powerful ways to extend human life As cell therapy and regenerative medicine continue to evolve, Ossium’s approach could help shift healthcare from reactive treatment to proactive, personalized immune system care. 📌 Learn more about how to navigate the healthcare system and find the right specialists: https://therapy4me.ai

    How Ossium Health is Changing Stem Cell Therapy and Regenerative Medicine
See All (90)

Ratings & Reviews

5
out of 5
3 Ratings

About

"Rx for Biotech" is a healthcare education podcast dedicated to helping patients, caregivers, and healthcare professionals understand the rapidly evolving world of advanced therapies - and how patients can access them. From cell therapies and gene therapies to radiopharmaceuticals, immunotherapies, and next-generation treatments for cancer and autoimmune disease, this channel bridges the gap between breakthrough science and real-world patient care. Hosted by Chris Leidli, founder of Genoplex and longtime host of the Rx for Biotech podcast, each episode features conversations with: • Biotech and pharmaceutical CEOs • Physician leaders and researchers • AI and tech leaders building tools to improve healthcare access • Innovators building the next generation of personalized therapies About Therapy4me.ai Therapy4me.ai is a consumer education and care-navigation platform designed to help patients find and connect with specialists at treatment centers offering personalized medicines and advanced therapies. Learn more: https://www.therapy4me.ai To learn more about Genoplex, please visit https://www.genoplex.ai

Information

  • Creator
    Podcast Host Chris Leidli
  • Years Active
    2020 - 2026
  • Episodes
    90
  • Rating
    Clean
  • Copyright
    © All rights reserved
  • Show Website
    Rx for Biotech

You Might Also Like