The Alignment Lab by Meredith DeSantos

Meredith DeSantos

What if success didn’t cost your peace? Welcome to The Alignment Lab — the podcast where high-achievers ditch outdated systems and unlock strategies that align with their energy. Join Meredith DeSantos, nervous system-first business strategist, as she blends Human Design, neuroscience, and nearly two decades of experience across entertainment, tech, and wellness to help you grow a business that feels as good as it looks. From A-list creatives to visionary founders, Meredith is celebrated for her ability to rapidly launch projects while increasing her clients' creative emotional intelligence.

  1. Unlocking Business Success with Human Design: A Live-Reading with Amanda Millien

    11/25/2025

    Unlocking Business Success with Human Design: A Live-Reading with Amanda Millien

    #14: In this episode of the Alignment Lab, we dive into the intersection of human design and business strategy with guest Amanda Millien, founder of Millien Media Creative Studio. We discuss how understanding and applying human design principles can better align your business practices with your innate strengths and tendencies. Amanda shares her insights on how she plans to transition from creator to mentor, helping clients not only rebrand visually but also communicate their journey effectively. We explore the importance of rest, self-care, and tapping into the right energy sources to avoid burnout and increase productivity. Tune in for a mix of business wisdom and personal anecdotes, including navigating motherhood and entrepreneurship. EPISODE TIMESTAMPS: 00:00 Introduction to the Alignment Lab 00:54 Meet Amanda Million: Visual Storytelling Expert 01:44 Human Design and Parenting 02:39 Understanding Projectors in Human Design 04:12 The Importance of Rest for Projectors 13:48 Navigating Emotional Authority 16:14 Mastering Your Craft and Overcoming Perfectionism 18:09 Embracing Your Role as a Mentor 19:52 Harnessing Community and Trusting the Universe 21:19 Your Highest Purpose: The Sacred Salesperson 21:46 The Divine Creative and Embracing Creativity 22:15 Exploring Group Mentorship and Rebranding 22:54 Focusing on Details and Effective Communication 23:30 The Idea Factory and Trusting the Process 24:20 Embracing Wholeness and Abundance 25:25 The Evolution of Self and Parenthood 27:07 Business Strategies and Mentorship Transition 33:35 Navigating Parenthood and Business Juggling 40:39 Final Thoughts and Exciting Future Plans RESOURCES Contact Amanda: MillienMedia@gmail.com Find her on IG HERE Don't know your HD? Grab your chart for free HERE Create Content that Converts based on your Human Design with the help of a social media expert HERE

    43 min
  2. From Music Artist to Mentor: Big Soph on Human Design, Leadership, and Creative Identity

    11/18/2025

    From Music Artist to Mentor: Big Soph on Human Design, Leadership, and Creative Identity

    #13: In this episode of The Alignment Lab, Big Soph (Sophie Steele) shares her journey from being a music artist to becoming a mentor and leader in the music industry. She discusses her experiences with human design, particularly as a manifestor, and how it influences her approach to creativity, leadership, and personal growth. The episode explores themes of vulnerability, emotional energy, and the importance of community and authenticity in both personal and professional realms. Big Soph emphasizes the need for rest, the power of mentorship, and the intersection of creativity and business, ultimately encouraging listeners to embrace their unique paths and the gold found in life's challenges. EPISODE TIMESTAMPS 00:00 The Journey into Music and Industry Insights 02:44 Understanding Manifestor Energy and Personal Growth 05:30 Navigating Autonomy and Collaboration 08:15 Finding Gold in Life's Challenges 11:27 The Role of Community and Personal Evolution 14:09 Pursuing Dreams and Balancing Hustle with Rest 16:56 Emotional Boundaries and Self-Care 19:39 The Power of Aha Moments and Divine Timing 22:38 Leadership and Abundance in Creativity 25:02 Current Projects and Future Aspirations 26:25 Empowering Creatives Through Mentorship 28:59 The Release Process: A Focused Approach 30:17 Complementary Strengths in Collaboration 33:00 Communication and Human Design in Business 36:18 Overcoming Fear and Embracing Leadership 40:17 The Power of Vulnerability in Authenticity RESOURCES Follow Big Soph on Instagram Check out ways to work with Big Soph HERE Don't know your HD? Grab your chart for free HERE Create Content that Converts based on your Human Design with the help of a social media expert HERE

    52 min
  3. Human Design for Creatives: How Projectors Thrive in the Music Industry with Michelle Garramone

    11/05/2025

    Human Design for Creatives: How Projectors Thrive in the Music Industry with Michelle Garramone

    In this special episode of the Alignment Lab, host Meredith DeSantos dives into a live human design reading for music industry veteran Michelle Garramone. They discuss everything from the challenges of using ManyChat as a projector to the intricacies of self-love and sobriety. Meredith also shares valuable insights on leveraging human design to create a business that feels authentic and aligned. Plus, Michelle opens up about her journey from working with a major country star to running her own indie label and education platform. Tune in to discover powerful aha moments and actionable strategies for aligning your business with your energetics. EPISODE TIMESTAMPS 00:00 Welcome to the Alignment Lab 00:54 Live Human Design Reading with Michelle Garramone 01:39 Challenges with ManyChat and Authentic Engagement 03:42 Understanding Projector Energy and Invitations 06:30 Aligning Social Media Strategy with Human Design 12:10 Exploring Human Design Gates and Branding 16:39 Balancing Creativity and Business as a Projector 26:55 Hosting Group Sessions and Building Community 28:56 Conversion Events and Group Hybrids 29:27 Masterclass Formats and Funnel Strategies 30:51 Overcoming Perfectionism and Embracing Trial and Error 32:52 Intuition, Self-Love, and Environmental Influences 34:13 Modeling Self-Love and Overcoming Childhood Challenges 37:21 Career Journey and Industry Challenges 44:59 Sobriety and Personal Growth 52:15 Final Thoughts and Content Strategy RESOURCES Grab your FREE Human Design Chart Here Check out Michelle on IG and her site! Use code LAB15 for 15% off your monthly membership for life inside The Aligned Content Lab, where we help you create content that converts likes into sales (without the burnout).

    53 min
  4. Designing Your Business to Align with Your Energetics (with Heather Leary)

    10/14/2025

    Designing Your Business to Align with Your Energetics (with Heather Leary)

    In this episode of The Alignment Lab, Meredith's joined by the lovely Heather Leary, founder of Salt & Chalk Studio — a UK-based brand and web designer for wellness founders who’s basically mastered the art of working with her energy, not against it. Heather and Meredith dive into what it really looks like to design your business around your Human Design — especially as a Projector — and how that shift changes everything from your work rhythm to your creative flow. She shares her story of leaving corporate marketing, taking a sabbatical for yoga teacher training, and how lockdown became the unexpected catalyst for starting her own soulful design studio. We get into all the good stuff: How to honor your energy (instead of trying to keep up with Generator hustle)What it looks like to brand from alignment — not aesthetics Building a business that actually supports your lifestyleThe power of authenticity, balance, and behind-the-scenes storytellingThis one’s for every creative or entrepreneur who’s tired of overworking their way to success — and ready to design a business that feels as good as it looks. EPISODE TIMESTAMPS00:00 – Welcome to The Alignment Lab 00:55 – Meet Heather Leary: Brand & Web Designer 01:42 – From Corporate to Yoga Teacher Training 02:10 – How Lockdown Sparked a Career Pivot 03:29 – Projector Energy and Sustainable Success 07:29 – Working in Flow, Not Force 17:53 – Soulful Branding and Client Work 23:02 – Expressing Emotion Through Art 23:34 – Balancing Feminine + Masculine Energy 24:49 – Corporate Life vs. Fulfillment 27:02 – The Start of a Yoga Brand 28:48 – Authenticity in Branding 34:09 – Why Website Templates Matter 44:01 – Outsourcing Without Losing Soul 46:34 – Final Thoughts RESOURCES: Grab your free Human Design HERE Join The Aligned Content Lab Membership HERE Sign up for the free Content that Converts Masterclass HERE Follow Heather Leary on IG and check out her website templates and offerings HERE

    48 min
  5. Unlocking Aligned Content Strategies: From Burnout to Breakthrough

    09/30/2025

    Unlocking Aligned Content Strategies: From Burnout to Breakthrough

    In this episode, Meredith pulls back the curtain on how hustle culture wreaks havoc on our nervous systems—and why the antidote isn’t “doing more,” but building strategies that actually work with your unique energy. She shares her own story of shifting from a Type-A, overachiever mindset into burnout, and how Human Design became the key to realignment. You’ll hear the truth about burnout and sensitivity (hint: they’re not flaws, they’re signals), and how to reframe them as powerful tools for growth. Meredith breaks down practical ways to create content that honors your energy type—so you can ditch algorithm panic, stop feeling guilty when you need rest, and build a rhythm that actually lasts. Together, you’ll dive into visibility fears, learn why your sensitivity is your superpower, and get a taste of what it looks like to create content that converts without burning out. Meredith also gives you a behind-the-scenes look at her new membership, The Aligned Content Lab, designed to help you craft magnetic content strategies rooted in Human Design and backed by social media best practices. Episode Breakdown:00:00 Welcome to The Alignment Lab00:55 Meredith’s journey through burnout03:03 What aligned action really looks like06:15 Reframing fear + visibility09:30 Human Design types in content creation12:36 Sensitivity as your superpower14:49 Closing thoughts + next steps RESOURCES: Grab your free Human Design HERE Join The Aligned Content Lab Waitlist and get a free AI tool to help you build aligned offers HERE Sign up for the free Content that Converts Masterclass HERE

    17 min
5
out of 5
10 Ratings

About

What if success didn’t cost your peace? Welcome to The Alignment Lab — the podcast where high-achievers ditch outdated systems and unlock strategies that align with their energy. Join Meredith DeSantos, nervous system-first business strategist, as she blends Human Design, neuroscience, and nearly two decades of experience across entertainment, tech, and wellness to help you grow a business that feels as good as it looks. From A-list creatives to visionary founders, Meredith is celebrated for her ability to rapidly launch projects while increasing her clients' creative emotional intelligence.