The Big Unlock

Rohit Mahajan & Ritu M. Uberoy

THE BIG UNLOCK PODCAST is a Healthcare Digital Transformation Podcast. Stay Updated on Healthcare’s Digital Transformation Trends. Featuring C-suite Leaders and Insights on Digital Health Innovation. Explore Emerging Healthcare Technologies with Rohit Mahajan and Ritu M. Uberoy.

  1. Healthcare Needs Real Disruption, Not Incremental Change

    APR 7

    Healthcare Needs Real Disruption, Not Incremental Change

    The Big Unlock · Dr. Stephen K. Klasko, Executive in Residence, General Catalyst & Board Chair, DocGo, Teleflex In this episode, Dr. Stephen K. Klasko, former CEO of Jefferson Health, Executive in Residence at General Catalyst, Board Chair at DocGo, Teleflex, and one of healthcare’s most provocative voices, challenges the industry to rethink its fundamental assumptions and move toward a more sustainable, patient-centered future. He argues that despite years of discussion around value-based care and digital transformation, true disruption has been limited because stakeholders remain unwilling to fundamentally change existing business models. Dr. Klasko argues that the healthcare system is broken, fragmented, expensive, and inequitable and that true disruption, like what Uber did to taxis or Amazon to retail, will demand that some players fail. He makes the case that the annual physical visit is a farce, and that continuous health narratives powered by wearables and AI companions are the future of proactive, personalized care. On the tech-provider collaboration front, Dr. Klasko identifies – founder ego, misaligned incentives, and EHR-era skepticism as the biggest barriers. He advocates for co-developing solutions, sharing equity, and building genuine partnerships. Dr. Klasko’s message to healthcare leaders is unambiguous: stop turning things around 360 degrees and start making real, uncomfortable changes. Take a listen. This guest appearance was facilitated through conversations initiated at Health Tech Summit by Cornell Tech.

    22 min
  2. Augmenting Care and Strengthening Trust with AI

    FEB 19

    Augmenting Care and Strengthening Trust with AI

    The Big Unlock · Dr. Andrea Willis, SVP & Chief Medical Officer, BlueCross BlueShield of Tennessee In this episode, Dr. Andrea Willis, SVP and Chief Medical Officer at BlueCross BlueShield of Tennessee, shares how payers can harness AI to advance affordable, accessible, and more human-centered care. From her clinical roots to leading population health, quality, and health equity initiatives, Dr. Willis brings a deeply personal commitment to service. She describes how AI is being deployed across care management and utilization management, not to replace clinicians or deny care, but to augment teams, accelerate evidence-based decisions, and close gaps in care. In care management, AI-powered summarization and prompting help staff stay fully present with members while improving engagement and measurable outcomes. In utilization management, transparency, evidence-based criteria, and clear documentation remain foundational to rebuilding provider trust. She also highlights that relevance matters more than data volume, and that guided self-service must balance automation with timely human escalation. Dr. Willis emphasizes transparency in prior authorization, cross-functional governance, AI literacy goals across the enterprise, and strong PHI protections. For here, scaling AI responsibly – through interoperability, collaboration, and measurable impact – is key to rebuilding trust and transforming the healthcare experience. Take a listen.

    24 min

Ratings & Reviews

5
out of 5
7 Ratings

About

THE BIG UNLOCK PODCAST is a Healthcare Digital Transformation Podcast. Stay Updated on Healthcare’s Digital Transformation Trends. Featuring C-suite Leaders and Insights on Digital Health Innovation. Explore Emerging Healthcare Technologies with Rohit Mahajan and Ritu M. Uberoy.

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