The Bob Harrington Show

Medscape

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The Bob Harrington Show is a podcast series of thoughtful interviews and discussions on topics at the core of cardiology and the practice of medicine.

29 DE OUT.

SMuRF-less: CV Prevention Beyond Traditional Risk Factors

Drs Harrington, Rodriguez, and Ridker discuss the changing field of cardiac prevention, where imaging fits in, and the new concept of standard modifiable risk factor-less patients. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association https://doi.org/10.1161/CIR.0000000000001078 Development and Validation of the American Heart Association's PREVENT Equations https://doi.org/10.1161/CIRCULATIONAHA.123.067626 C-Reactive Protein and Cardiovascular Risk Among Women With No Standard Modifiable Risk Factors: Evaluating the 'Smurf-Less but Inflamed' https://doi.org/10.1093/eurheartj/ehaf658 Mortality in STEMI Patients Without Standard Modifiable Risk Factors: A Sex-Disaggregated Analysis of SWEDEHEART Registry Data https://doi.org/10.1016/S0140-6736(21)00272-5 Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women https://www.nejm.org/doi/10.1056/NEJMoa2405182 Statins for the 'SMuRFLess But Inflamed': Silent Vascular Inflammation and the Challenge of Translational Science https://doi.org/10.1016/j.jacbts.2025.101318 VERVE-101: A Promising CRISPR-Based Gene Editing Therapy That Reduces LDL-C and PCSK9 Levels in HeFH Patients https://academic.oup.com/ehjcvp/article/10/2/89/7492807 You may also like: Hear John Mandrola, MD, give a summary and his perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

24min
7 DE OUT.

Unlocking Longevity: Aging Reimagined

Cardiologist and author Eric Topol discusses the science of longevity, why the key to healthy aging is prevention, and the perils of a fixation on reversing ageing. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington Super Agers: An Evidence-Based Approach to Longevity https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666 Wellderly study https://www.scripps.edu/science-and-medicine/translational-institute/translational-research/genomic-medicine/wellderly/ Lotte Bjerre Knudsen https://erictopol.substack.com/p/lotte-bjerre-knudsen-the-scientist Organ aging signatures in the plasma proteome track health and disease https://doi.org/10.1038/s41586-023- Deep Medicine https://drerictopol.com/portfolio/deep-medicine/ You may also like: Hear John Mandrola, MD, give a summary and his perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

23min
15 DE SET.

Nobel Laureate on Touch and the Joy of Scientific Discovery

The 2021 winner of the Nobel Prize in medicine, Ardem Patapoutian speaks of his love for science, why he wishes he had an MD, and the importance of getting out of the lab to inspire young people. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit: https://www.medscape.com/author/bob-harrington Nobel Prize in Physiology or Medicine 2021 https://pubmed.ncbi.nlm.nih.gov/39429349/ https://www.nobelprize.org/prizes/medicine/2021/press-release/ Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels https://pubmed.ncbi.nlm.nih.gov/20813920/ PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex https://doi.org/10.1126/science.aau6324 PIEZO Ion Channels in Cardiovascular Functions and Diseases https://doi.org/10.1161/CIRCRESAHA.123.322798 You may also like: Hear John Mandrola, MD, with his summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

24min
23 DE JUN.

Academic Entrepreneurship Key for Clinician Researchers Given NIH Funding Uncertainty

Bob Harrington chairs a panel with two early-career physician researchers and the head of a large research institute on what the future holds in lights of NIH funding cuts. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington You may also like: Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

25min
5 DE MAI.

To Train Physicians of the Future We Can't Be Stuck in the Past

The rejection by the ABMS of a certification board run by cardiologists prompted this discussion on how medical training should change and the best methods to assess clinical competency. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington New Cardiology Board Denied but 'Not Done With This Fight' https://www.medscape.com/viewarticle/new-cardiology-board-denied-not-done-this-fight-2025a10006j8 You may also like: Hear Dr John Mandrola's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

28min
10 DE ABR.

For America First, Invest in Science and the NIH

A panel discussion of a Presidential Advisory from the American Heart Association that outlines the importance of funding for scientific research and the need for a robust National Institutes of Health. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington INCLUDE URLS and full titles for some of the pertinent studies cited. You may also like: Principles for the Future of Biomedical Research in the United States and Optimizing the National Institutes of Health: A Presidential Advisory From the American Heart Association https://doi.org/10.1161/cir.0000000000001319 The Role of Public-Sector Research in the Discovery of Drugs and Vaccines." https://www.nejm.org/doi/full/10.1056/NEJMsa1008268 Comparison of Research Spending on New Drug Approvals by the National Institutes of Health vs the Pharmaceutical Industry, 2010-2019 https://pubmed.ncbi.nlm.nih.gov/37115539/ Hear John Mandrola, MD's summary and perspective on the top cardiology news each week on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

30min
30 DE JAN.

Cardiology 2024 Highlights and Predictions for 2025

Drs Harrington and Gibson review their picks for the top cardiology trials of 2024 and look ahead to 2025, particularly what health topics may be prioritized by the new administration. This podcast is intended for healthcare professionals only. To read a transcript or to comment https://www.medscape.com/author/bob-harrington Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction (REDUCE AMI) https://www.nejm.org/doi/abs/10.1056/NEJMoa2401479 Intensive Blood-Pressure Control in Patients with Type 2 Diabetes (BPROAD) https://doi.org/10.1056/nejmoa2412006 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis EARLY TAVR https://www.nejm.org/doi/full/10.1056/NEJMoa2405880 Asundexian versus Apixaban in Patients with Atrial Fibrillation (OCEANIC-AF) https://doi.org/10.1056/NEJMoa2407105 In the Wake of OCEANIC-AF, Is Equipoise Regarding Factor XI Inhibition Still Afloat? https://www.jacc.org/doi/10.1016/j.jacc.2024.10.105 Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trial https://doi.org/10.1016/S0140-6736(24)00413-6 Preventive Coronary Stents: Not There Yet https://www.medscape.com/viewarticle/preventive-coronary-stents-not-there-yet-2024a10006yr Speech by Commissioner Robert M. Califf to the House of Medicine June 16, 2023 https://www.fda.gov/news-events/speeches-fda-officials/speech-commissioner-robert-m-califf-house-medicine-06162023 Evolution of Single-Lead ECG for STEMI Detection Using a Deep Learning Approach https://doi.org/10.1016/j.ijcard.2021.11.039 From ST-Segment Elevation MI to Occlusion MI: The New Paradigm Shift in Acute Myocardial Infarction https://doi.org/10.1016/j.jacadv.2024.101314 You may also like: Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

36min
10/12/2024

Does ST-Elevation MI Need a Rebrand to 'Occlusion MI'?

A review paper prompted a discussion among cardiologists Bob Harrington, Manesh Patel, and Michael Gibson on whether the ST-segment elevation myocardial infarction paradigm needs an update. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington From ST-Segment Elevation MI to Occlusion MI: The New Paradigm Shift in Acute Myocardial Infarction https://doi.org/10.1016/j.jacadv.2024.101314 Angiographic and Clinical Outcomes Among Patients With Acute Coronary Syndromes Presenting With Isolated Anterior ST-Segment Depression: A TRITON-TIMI 38 Substudy https://doi.org/10.1016/j.jcin.2010.05.012 Treatment Time and In-Hospital Mortality Among Patients With ST-Segment Elevation Myocardial Infarction, 2018-2021 https://jamanetwork.com/journals/jama/fullarticle/2798440 Evolution of Single-Lead ECG for STEMI Detection Using a Deep Learning Approach https://doi.org/10.1016/j.ijcard.2021.11.039 Implantable Cardiac Alert System for Early Recognition of ST-Segment Elevation Myocardial Infarction https://doi.org/10.1016/j.jacc.2019.01.014 TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis https://doi.org/10.1161/CIRCRESAHA.117.311466 Early Versus Delayed Invasive Intervention in Acute Coronary Syndromes https://www.nejm.org/doi/full/10.1056/NEJMoa0807986 Translating AI for the Clinician https://doi.org/10.1001/jama.2024.21772 A Novel Breakthrough in Wrist-Worn Transdermal Troponin-I-Sensor Assessment for Acute Myocardial Infarction https://doi.org/10.1093/ehjdh/ztad015 A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI (CELEBRATE) https://clinicaltrials.gov/study/NCT04825743 Selatogrel Outcome Study in Suspected Acute Myocardial Infarction (SOS-AMI) https://clinicaltrials.gov/study/NCT04957719 You may also like: Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

20min

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13 avaliações

Excellent Work

13/10/2019

CoolMD

Really well done .

The Bob Harrington Show is a podcast series of thoughtful interviews and discussions on topics at the core of cardiology and the practice of medicine.