The Deep Six

Speakeasy Podcast Network

The Deep Six Podcast is a series of discussions about health, wellness, functional medicine and the journey we all take through life. How his six point model impacts everyone at any age . Each episode, Dr. James Lewerenz invites doctors, scientists, therapists, free thinkers, musicians, entertainers and anyone else to have a chat about living a purposeful, impactful healthy life. Thriving not just surviving!

  1. Gut Health Starts in the Kitchen: Practical Nutrition That Works | The Deep Six | Episode 40

    FEB 2

    Gut Health Starts in the Kitchen: Practical Nutrition That Works | The Deep Six | Episode 40

    This week on The Deep Six, Dr. James Lewerenz sits down with Chef Nishan Andonian of Entice Catering LLC to explore the powerful connection between food, flavor, and long-term health. Chef Nishan shares how scratch cooking, fresh herbs, and thoughtful techniques can transform clean eating into something sustainable and deeply satisfying. Together, they discuss gut health, gluten sensitivity, protein intake, and why flavorful meals help prevent overeating and support metabolic health. The conversation also tackles popular weight loss injections, with Dr. Lewerenz explaining when GLP-1 therapies can be helpful and why improper use risks muscle loss and long-term decline. From bone broth and gluten-free alternatives to simple first steps in the kitchen, this episode reinforces a core principle: real health is built through intentional nourishment, not shortcuts. Timestamps 00:00 Welcome to the Deep Six Podcast 02:27 Scratch Cooking 05:50 Culinary Creations and Services 08:40 Personal Health Goals and Cooking 12:17 Gluten-Free Cooking Techniques 18:10 Herbs, Spices, and Protein Sources 22:09 Staying Full and Favorite Meals 26:13 Chef’s Advice for Home Cooks 31:10 GLP-1 Injections and Muscle Loss Guest Links: Entice Catering Website: https://entice-family-meals.square.site About: Dr. James Lewerenz takes a multifaceted approach to impact the lives of his patients. Using functional medicine, he looks at every patient on an individual, case-by-case basis, asks lots of questions, and works diligently to find the root cause of the individual's chronic pain or illness. Dr. Lewerenz is passionate and dedicated to bringing his personal experience, knowledge, and training to enhance one’s quality of life, at any age. Be well! Longevity Health Institute 633 E South Blvd. Ste 2200 Rochester Hills, MI 48307  (248) 289-6643 https://www.longevityhealthinstituteinc.com/

    40 min
  2. The Rhythm of Recovery and Performance | The Deep Six | Episode 39

    JAN 19

    The Rhythm of Recovery and Performance | The Deep Six | Episode 39

    On this episode of The Deep Six, Dr. James Lewerenz sits down with Nik Hughes, drummer for the rock band Bush, to explore the physical, mental, and emotional demands of life on tour. Nik shares how drumming at a high level requires intentional training, long warmups, hydration, and recovery, especially as he ages and manages past injuries. The conversation connects performance with longevity, highlighting how fitness, nutrition, sleep, and mindset support both musicians and everyday professionals. Nik also opens up about balancing touring with family life and caring for a child with type 1 diabetes. This episode reinforces how sustainable health habits, consistency, and purpose allow people to perform at their best while protecting long-term well-being. Chapters 00:00 Introduction to Nik Hughes, Drummer for Bush 05:15 Drumming Inspirations and Influences 07:30 Rock Doc to Rocker: Health on Tour 11:04 Balancing Family and a Musician’s Life 16:19 Travel Experiences and Cultural Connections 21:00 Fitness Routine and Injury Recovery 29:34 Dietary Habits and On-Tour Nutrition 34:08 Evolution of Musician Lifestyles 39:04 Bush’s Future and Band Culture 42:44 Future of Type 1 Diabetes Treatment Guest Links: Personal Website: https://www.nikhughesdrum.com/ Band Website: https://www.bushofficial.com/ About: Dr. James Lewerenz takes a multifaceted approach to impact the lives of his patients. Using functional medicine, he looks at every patient on an individual, case-by-case basis, asks lots of questions, and works diligently to find the root cause of the individual's chronic pain or illness. Dr. Lewerenz is passionate and dedicated to bringing his personal experience, knowledge, and training to enhance one’s quality of life, at any age. Be well! Longevity Health Institute 633 E South Blvd. Ste 2200 Rochester Hills, MI 48307  (248) 289-6643 https://www.longevityhealthinstituteinc.com/

    51 min
  3. Inside the Six-Point Model: An AMA on Prevention and Longevity | The Deep Six | Episode 38

    12/22/2025

    Inside the Six-Point Model: An AMA on Prevention and Longevity | The Deep Six | Episode 38

    In this AMA episode of The Deep Six Podcast, Dr. James Lewerenz answers listener questions that span daily habits, emerging diagnostics, and long-term brain and heart health. He walks through his personal non-negotiables, including gratitude, movement, heat and cold exposure, and intentional community, explaining how small daily practices shape physiology over time. Dr. Lewerenz also highlights newer biomarkers for cognitive decline, advances in genetic cancer screening, and why cardiac imaging plays a growing role in proactive care. Throughout the conversation, he reinforces the importance of viewing health through the Six Point Model and thinking beyond short-term goals. This episode emphasizes prevention, clarity, and playing the long game so listeners can protect their brains, hearts, and overall vitality for decades to come. Chapters 00:00 Introduction to the Deep Six 02:56 Daily Routine and Non-Negotiables 06:50 New Biomarkers and Genetic Screening 12:12 Deeper Dive into Heart Health 14:47 Toxins and Cognitive Decline 19:27 Long Game for Lifelong Health About: Dr. James Lewerenz takes a multifaceted approach to impact the lives of his patients. Using functional medicine, he looks at every patient on an individual, case-by-case basis, asks lots of questions, and works diligently to find the root cause of the individual's chronic pain or illness. Dr. Lewerenz is passionate and dedicated to bringing his personal experience, knowledge, and training to enhance one’s quality of life, at any age. Be well! Longevity Health Institute 633 E South Blvd. Ste 2200 Rochester Hills, MI 48307  (248) 289-6643 https://www.longevityhealthinstituteinc.com/

    21 min
  4. East Meets West: Where Chinese Medicine and Modern Longevity Align | The Deep Six | Episode 37

    12/08/2025

    East Meets West: Where Chinese Medicine and Modern Longevity Align | The Deep Six | Episode 37

    On this episode of The Deep Six Podcast, Dr. James Lewerenz sits down with Dr. Samantha Buchanan, DACM, owner of Pointe Acupuncture & Integrative Medicine, to explore how Chinese medicine and Western functional medicine can work together in modern longevity care. Dr. Buchanan shares how a serious running injury led her from a pre-med path into acupuncture, herbs, and integrative practice, along with what comprehensive intake and pattern-based assessment look like in real life. They break down how acupuncture may support the autonomic nervous system and vagus nerve, helping with stress, sleep, chronic pain, and recovery, and why practitioner training and licensure matter when symptoms could signal something more serious. The conversation also touches on fertility and IVF support, plus the “five pillars” fundamentals, including the often-overlooked impact of social connection on long-term health. Chapters 00:00 Introduction to Dr. Sam’s Practice 04:07 Journey to Chinese Medicine 08:39 Acupuncture Experience and Diagnosis 14:24 Acupuncture Approaches and Specialties 19:16 The Importance of Licensed Practitioners 23:56 Acupuncture for Stress and Infertility 33:49 Social Life and Generational Wisdom 43:20 Acupuncture for Pets and Powerful Results Guest Links: Point Acupuncture: https://www.pointeacupuncture.com/ About: Dr. James Lewerenz takes a multifaceted approach to impact the lives of his patients. Using functional medicine, he looks at every patient on an individual, case-by-case basis, asks lots of questions, and works diligently to find the root cause of the individual's chronic pain or illness. Dr. Lewerenz is passionate and dedicated to bringing his personal experience, knowledge, and training to enhance one’s quality of life, at any age. Be well! Longevity Health Institute 633 E South Blvd. Ste 2200 Rochester Hills, MI 48307  (248) 289-6643 https://www.longevityhealthinstituteinc.com/

    47 min
  5. How Nitric Oxide Supports Vascular Health and Healthy Aging | The Deep Six | Episode 36

    11/24/2025

    How Nitric Oxide Supports Vascular Health and Healthy Aging | The Deep Six | Episode 36

    On this episode of The Deep Six, Dr. James Lewerenz sits down with Cathy Eason, MS, BCHN, FNTP, Chief Science Officer at Berkeley Life, to unpack why nitric oxide is so central to vascular health, aging, and daily performance. Cathy explains how nitric oxide works in the body, why levels decline with age, and why endothelial health must be a lifelong priority, not just a concern after symptoms show up. They explore the difference between amino acid-based approaches like arginine and clinically studied dietary nitrates, the role of the oral microbiome and saliva in nitric oxide production, and how support can impact blood pressure, energy, recovery, cognition, sexual wellness, and more. Cathy also previews upcoming research in peri- and post-menopausal women and shares practical reasons nitric oxide support belongs in every long-term prevention strategy. Timestamps 00:00 Welcome & Guest Introduction 02:16 Cathy’s Background & Nitric Oxide Importance 05:41 Gratitude and Personal Insights 07:04 What is Nitric Oxide? 12:26 N.O. Supplementation & Benefits 17:44 Arginine vs. Nitrate Pathways & Oral Health 23:12 The Entero-Salivary Pathway 27:34 Top Benefits of Nitric Oxide 33:03 Future Research & Menopause Focus 38:43 Conclusion & Call to Action Guest Links: https://berkeleylife.com/ About: Dr. James Lewerenz takes a multifaceted approach to impact the lives of his patients. Using functional medicine, he looks at every patient on an individual, case-by-case basis, asks lots of questions, and works diligently to find the root cause of the individual's chronic pain or illness. Dr. Lewerenz is passionate and dedicated to bringing his personal experience, knowledge, and training to enhance one’s quality of life, at any age. Be well! Longevity Health Institute 633 E South Blvd. Ste 2200 Rochester Hills, MI 48307  (248) 289-6643 https://www.longevityhealthinstituteinc.com/

    42 min
  6. Trust, Time, and Triage: What Really Happens in the ER | The Deep Six | Episode 35

    10/27/2025

    Trust, Time, and Triage: What Really Happens in the ER | The Deep Six | Episode 35

    On this episode of The Deep Six Podcast, Dr. James Lewerenz welcomes emergency medicine physician Dr. Roya Caloia for a powerful conversation about the realities of life in the ER. Dr. Caloia shares how her journey shifted from public health and OB-GYN aspirations to discovering her passion for emergency medicine, where every day offers an opportunity to impact lives during their most critical moments. She explains the challenges of modern healthcare, including the decline of long-term patient–doctor relationships, increased ER demand, and the troubling rise of anxiety, depression, and other mental health issues. Dr. Caloia also offers practical advice for patients, including the importance of bringing medication lists, being patient with wait times, and trusting the ER team’s priorities. This episode highlights both the intensity and honor of emergency medicine, blending honesty with hope. Timestamps 00:00 Welcome & ER Doctor’s Journey 04:15 The ER as a ‘Dumping Ground’ 11:13 Healthcare System Challenges 19:20 ER Stories and Realities 27:06 DO Training and Philosophy 32:25 Dr. Caloia’s Leadership Role 34:51 Navigating the ER: A Patient’s Guide 39:39 Essential ER Preparedness Tips 43:06 Don’t Fear the ER 46:02 Rising Mental Health Crisis 50:08 Gratitude and Life’s Simple Pleasures About: Dr. James Lewerenz takes a multifaceted approach to impact the lives of his patients. Using functional medicine, he looks at every patient on an individual, case-by-case basis, asks lots of questions, and works diligently to find the root cause of the individual's chronic pain or illness. Dr. Lewerenz is passionate and dedicated to bringing his personal experience, knowledge, and training to enhance one’s quality of life, at any age. Be well! Longevity Health Institute 633 E South Blvd. Ste 2200 Rochester Hills, MI 48307  (248) 289-6643 https://www.longevityhealthinstituteinc.com/

    57 min
  7. Ask Me Anything: Building Strength, Restoring Sleep, and Boosting Energy | The Deep Six | Episode 34

    10/13/2025

    Ask Me Anything: Building Strength, Restoring Sleep, and Boosting Energy | The Deep Six | Episode 34

    Dr. Lewerenz is back with his second AMA, answering listener questions that speak to common challenges many of us face. He explains why aging and autoimmunity can lead to frequent falls and fractures and offers ways to build stronger bones, protect balance, and stay active at any age. He also shares practical strategies for better sleep, including magnesium, melatonin, grounding sheets, peptides, and the importance of consistent sleep routines. You’ll hear what’s new in the peptide world, the growing shift to oral GLP-1 medications, and why B12 injections remain a powerful tool for energy, mood, and nerve health. With real-life stories, science-based advice, and decades of experience, this AMA gives listeners clear steps to support their health and thrive, not just survive. Chapters 00:00 Welcome & Deep Six Model Overview 02:29 Falls, Fractures & Autoimmunity 08:10 Decades of Sleep Troubles 16:30 New in the Peptide World 18:39 The Importance of B12 About: Dr. James Lewerenz takes a multifaceted approach to impact the lives of his patients. Using functional medicine, he looks at every patient on an individual, case-by-case basis, asks lots of questions, and works diligently to find the root cause of the individual's chronic pain or illness. Dr. Lewerenz is passionate and dedicated to bringing his personal experience, knowledge, and training to enhance one’s quality of life, at any age. Be well! Longevity Health Institute 633 E South Blvd. Ste 2200 Rochester Hills, MI 48307  (248) 289-6643 https://www.longevityhealthinstituteinc.com/

    23 min
  8. Structural Health Matters: How Your Spine Shapes Your Life | The Deep Six | Episode 33

    09/29/2025

    Structural Health Matters: How Your Spine Shapes Your Life | The Deep Six | Episode 33

    On this episode of The Deep Six Podcast, Dr. James Lewerenz welcomes world-renowned neurosurgeon Dr. Daniel Fahim for an in-depth discussion on spine health, chronic pain, and the latest surgical advances. Dr. Fahim, recognized among the nation’s top neurosurgeons, shares his journey from early fascination with the brain to performing over 700 surgeries a year. He explains how minimally invasive spine techniques and disc replacements are transforming patient recovery, reducing pain, and preserving mobility compared to traditional fusions. The conversation also highlights warning signs of spinal cord injury, the importance of timely care to prevent chronic pain, and why patient expectations play a critical role in recovery. Dr. Fahim emphasizes fitness, motion preservation, and trust between doctor and patient as keys to lasting outcomes. This episode offers both education and reassurance for anyone facing structural challenges that impact quality of life. Chapters 00:00 Introduction to Dr. Daniel Fahim 02:47 Dr. Fahim’s Background and Reputation 05:38 Passion for Neurosurgery and Spine Health 08:40 Transformative Cancer Cases 11:24 Advances in Spine Surgery: Fusion vs. Replacement 15:50 Choosing a Spine Surgeon & First Surgery 19:27 International Missionary Work & Post-Surgery Recovery 22:12 Warning Signs of Spinal Cord Injury 27:08 Surgeon’s Fitness and Patient Expectations 30:08 Personal Spine Journey and MRI Review 37:53 Minimally Invasive Spine Surgery Benefits 40:23 Patient Empowerment and Trust 43:00 Conclusion and Contact Information Guest Links: Website: drdanielfahim.com About: Dr. James Lewerenz takes a multifaceted approach to impact the lives of his patients. Using functional medicine, he looks at every patient on an individual, case-by-case basis, asks lots of questions, and works diligently to find the root cause of the individual's chronic pain or illness. Dr. Lewerenz is passionate and dedicated to bringing his personal experience, knowledge, and training to enhance one’s quality of life, at any age. Be well! Longevity Health Institute 633 E South Blvd. Ste 2200 Rochester Hills, MI 48307  (248) 289-6643 https://www.longevityhealthinstituteinc.com/

    46 min
5
out of 5
19 Ratings

About

The Deep Six Podcast is a series of discussions about health, wellness, functional medicine and the journey we all take through life. How his six point model impacts everyone at any age . Each episode, Dr. James Lewerenz invites doctors, scientists, therapists, free thinkers, musicians, entertainers and anyone else to have a chat about living a purposeful, impactful healthy life. Thriving not just surviving!