The Gary Null Show

Progressive Radio Network

Gary takes on the real issues that the mainstream media is afraid to tackle. Tune in to find out the latest about health news, healing, politics, and the economy.

  1. 10H AGO

    The Gary Null Show 2-9-26

    Boosting a Natural Molecule (NAD+) Reverses Alzheimer’s Brain Damage in New Study University of Oslo & Ullevaal University Hospital (Norway), February 8, 2026   One of the key drivers of brain dysfunction in Alzheimer’s disease (AD) is the protein tau. Under normal conditions, tau helps maintain the internal structure of neurons, supporting the transport systems that allow nerve cells to function properly. In Alzheimer’s disease, however, tau becomes abnormally modified and begins to clump together. These aggregates interfere with normal cellular transport, damage neurons, and ultimately contribute to memory impairment. Now, an international team of scientists has identified a previously unrecognized way to protect the brain from this degeneration. Their research shows that increasing levels of the naturally occurring molecule NAD⁺ can counteract neurological damage linked to Alzheimer’s disease.  Previous research has suggested that boosting NAD⁺ using precursor compounds such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) can produce beneficial effects in animal models of AD and in early-stage clinical studies. However, the biological processes responsible for these effects have remained poorly understood,” explains first author Alice Ruixue Ai. The new study reveals that NAD⁺ works through a previously unidentified RNA-splicing pathway. This pathway is regulated by a protein called EVA1C, which plays an essential role in the process of RNA splicing. RNA splicing allows a single gene to produce multiple isoforms of a protein, and one isoform may show distinctive effects on the other isoforms. Its dysregulation is one of the most recently acknowledged risk factors for AD.

    43 min
  2. 3D AGO

    The Gary Null Show - 2/6/26

    HEALTH NEWS   Choline intake in pregnancy linked to lower inflammation Fatty acids found to influence immune defense during chronic infections Online shopping and social media use linked to higher stress levels Scientists Discover Natural Compounds With Unexpected Benefits for Skin, Anti-Aging, and Heart Health Discrimination damages the body—and makes victims age faster   Choline intake in pregnancy linked to lower inflammation Cornell University, February 5 2026 (Eurekalert)   A new Cornell University study suggests that choline, a nutrient many pregnant people consume too little of, may play an underappreciated role in keeping inflammation in check during pregnancy. Choline is an essential nutrient involved in many biological processes, including cell membrane structure, neurotransmitter production, methylation, immune cell receptor agonism, and fetal brain development, and some of these biochemical processes play a role in the regulation of inflammation. It is found primarily in eggs, meat, fish, dairy and some legumes and cruciferous vegetables. Researchers analyzed data from more than 1,300 pregnant participants enrolled in the Alberta Pregnancy Outcomes and Nutrition (APrON) cohort, one of the most detailed long-running pregnancy nutrition studies in North America. They found that higher recent dietary choline intake was associated with lower levels of inflammation in the third trimester. Most strikingly, participants with the highest choline intakes had dramatically lower odds of having clinically elevated inflammation than those with the lowest intakes.The current recommendation for choline during pregnancy is 450 mg, but there’s some evidence that that may not be enough.     Fatty acids found to influence immune defense during chronic infections University of California at San Diego, February 5 2026 (Medical Xpress) Our immune system implements an array of strategies to combat threatening infections. White blood cells called cytotoxic T lymphocytes or "CD8 T cells" are soldiers of the immune system, serving as defensive agents that fight invading pathogens. When CD8 T cells reach the point of exhaustion, their protective capabilities decline and the immune system is much less effective. University of California San Diego immunologists have now studied the influences related to metabolism and the environment surrounding CD8 T cells. Their study led to intriguing new insights on the role of fatty acids in chronic infections and other persistent conditions, such as tumors. The research focused on metabolites, including small molecules such as amino acids, sugars, and lipids, in mice that play key roles in metabolism and its many functions and pathways. The study examined how such metabolites circulating in the blood change during short-lived or long-lasting viral infections. They discovered that an ongoing viral infection causes a brief but striking shift in the availability of nutrients in the early stages after infection. They saw levels of fatty acids increase during the first week after infection, associated with infection-induced changes in eating behavior and fat breakdown. At the same time, a special group of exhausted CD8 T cells with stem-like properties was found to absorb and store more fat than other T cells. These cells were able to use fatty acids as an energy source to power their mitochondria, the cell's energy producers. When fatty acids were provided later during chronic infection, the number of stem-like T cells expanded.   Online shopping and social media use linked to higher stress levels     Aalto University (Finland), January 9 2026 (News-Medical) Planning to save time by doing your shopping online? If so, it's possible you're not doing your well-being any favors. A study from Aalto University in Finland has found that online shopping is more strongly linked to stress than reading the news, checking your inbox or watching adult entertainment.  Previous studies have shown that social media and online shopping are often used to relieve stress. However, the new results show that a rise in social media use or online shopping is linked to an increase in self-reported stress across multiple user groups and across devices. The study found that users of YouTube and streaming services, as well as online gamers, also reported increased stress levels. For people experiencing high-stress, time spent on social media was twice more likely to be linked to stress as compared to time spent on gaming. Somewhat surprisingly, people who spent a lot of time on news sites reported less stress than others. On the other hand, those who already experienced a lot of stress didn't spend much time on news sites. Overall, the study found a strong connection between internet use, in general, and heightened stress, especially among those who already experienced a lot of stress in daily life. Women reported more stress than men, and the older and wealthier the participant, the less stress they experienced.   Scientists Discover Natural Compounds With Unexpected Benefits for Skin, Anti-Aging, and Heart Health Meijo University (Japan), February 5, 2026 (SciTech Daily) Scientists have found that certain natural compounds produced by algae and cyanobacteria may offer benefits beyond sun protection, including support for skin health and cardiovascular function. In lab experiments, two mycosporine-like amino acids were found to do more than soak up ultraviolet light. They also slowed down a major enzyme tied to blood pressure control, while showing antioxidant and anti-aging activity. One enzyme, Porphyra-334, is abundant in edible seaweed, which is already consumed widely in many countries. This raises the possibility that everyday foods may contain underappreciated bioactive compounds worthy of further health-related research.These compounds, called mycosporine-like amino acids (MAAs), are produced by seaweeds and other tiny organisms that spend their lives exposed to intense light. MAAs work like built in sun filters by absorbing ultraviolet (UV) radiation before it can harm cells. One of the most notable findings came from experiments on the inhibiting the angiotensin-converting enzyme ACE, a key regulator of blood pressure. Many widely prescribed hypertension drugs work by blocking ACE. Both compounds reduced the activity of this enzyme in laboratory tests, marking the first report of such an effect for MAAs. Although the observed effects were moderate and measured outside the human body, the discovery opens a new direction for future research.     Discrimination damages the body—and makes victims age faster University of Montreal, January 19 2026 (Medical Xpress) Has being discriminated against as an LGBTQ+ person been so bad, the stress so heavy, that the victim can literally feel it in their bones? Well, it turns out that's exactly what happens: discrimination damages the body and brain. That's the conclusion of a new study by researchers at Université de Montréal, who found that discrimination against sexually and gender-diverse people leaves measurable biological traces in the body—so much so, it should be considered a chronic health burden. Published in Psychoneuroendocrinology, the study was done on 357 Montreal adults aged 18 to 79: They included 129 cisgender sexual minority men and women, 96 transgender and non-binary people, and 72 cisgender heterosexual men and women. UdeM researchers measured the participants' allostatic load, the cumulative biological wear-and-tear associated with chronic stress. They looked at 16 biomarkers affecting the subjects' cardiovascular, metabolic, neuroendocrine and immune systems. Results show that major life experiences of discrimination and daily microaggressions were positively associated with allostatic load. This means that these two types of discriminatory events independently contribute to physiological dysregulation, creating a cumulative health burden and accelerated aging. The study revealed significant disparities: people on the male spectrum (cisgender and transgender men) had the highest levels of allostatic load, while sexual minority men (bisexual and gay) also showed high levels of biological stress.   The Boring Historian Clip IT JUST HAPPENED: $7 Trillion Wiped Out In 36 Hours (Bigger Than 2008) https://www.youtube.com/watch?v=TtBzk06RoS0

    1h 3m
  3. JAN 30

    The Gary Null Show - 1/30/26

    HEALTH NEWS   Wild Blueberries May Benefit the Heart, Metabolism, and Microbiome Nitrate in drinking water linked to increased dementia risk while nitrate from vegetables is linked to a lower risk, researchers find   Afternoon naps clear up the brain and improve learning ability Screen time may increase body fat in children Simple dietary change may slow liver cancer in at-risk patients Wild Blueberries May Benefit the Heart, Metabolism, and Microbiome University of Maine & Florida State University, January 28, 2026 (SciTech Daily) A newly published scientific review brings together a growing body of research on how wild blueberries may influence cardiometabolic health. This area of health includes measures such as blood vessel function, blood pressure, blood lipids (cholesterol and triglycerides), and blood sugar (glucose). The review was developed following an expert symposium. Twelve specialists took part, representing fields that included nutrition, food science, dietetics, nutrition metabolism and physiology, cardiovascular and cognitive health, gut health and microbiology, and preclinical and clinical research models.  The paper evaluates findings from 12 human clinical trials conducted over 24 years across four countries that examined the cardiometabolic effects of wild blueberries. Across the clinical research examined, improvements in blood vessel function stand out as one of the most reliable findings. Studies included in the review suggest that wild blueberries may support endothelial function (or how well blood vessels relax and respond to stimuli). Some trials reported effects within hours of a single serving, while others observed benefits after consistent intake over weeks or months. In one six-week clinical study highlighted in the review, adults who consumed 25 grams of freeze-dried wild blueberry powder each day showed increases in beneficial Bifidobacterium species. The authors identify the gut microbiome as a likely contributor to the cardiometabolic effects linked to wild blueberries. The review also suggests wild blueberry intake may support certain aspects of cognitive performance. Improvements were observed in measures such as thinking speed and memory. Several of the reviewed studies reported clinically meaningful improvements in blood pressure, blood sugar regulation, and lipid markers, including total cholesterol, LDL cholesterol, and triglycerides, after weeks of wild blueberry consumption.   Nitrate in drinking water linked to increased dementia risk while nitrate from vegetables is linked to a lower risk, researchers find   Edith Cowan University (Australia) &  Danish Cancer Research Institute, January 28 2026 (Eurekalert) New research from Edith Cowan University (ECU) and the Danish Cancer Research Institute (DCRI) investigated the association between the intake of nitrate and nitrite from a wide range of different sources, and the associated risk of dementia.  The research, which investigated the association between source-specific nitrate and nitrite intake and incident and early-onset dementia, followed more than 54,000 Danish adults for up to 27 years and found that the source of nitrate was of critical importance in a diet.  The researchers found that people who ate more nitrate from vegetables had a lower risk of developing dementia, while those who consumed more nitrate and nitrite from animal foods, processed meats, and drinking water, had a higher risk of dementia.  When we eat nitrate-rich vegetables, we are also eating vitamins and antioxidants which are thought to help nitrate form the beneficial compound, nitric oxide, while blocking it from forming N-nitrosamines which are carcinogenic and potentially damaging to the brain.  Unlike vegetables, animal-based foods don't contain these antioxidants. In addition, meat also contains compounds such as heme iron which may actually increase the formation of N-nitrosamines. This is why nitrate from different sources may have opposite effects on brain health.   This is the first time that nitrate from drinking water has been linked to higher risks of dementia. The study found that participants exposed to drinking-water nitrate at levels below the current regulatory limits, had a higher rate of dementia.   Water doesn't contain antioxidants that can block formation of N-nitrosamines. Without these protective compounds, nitrate in drinking water may form N-nitrosamines in the body.   Afternoon naps clear up the brain and improve learning ability University of Freiburg (Germany) & University of Geneva, January 28 2026 (Eurekalert) Even a short afternoon nap can help the brain recover and improve its ability to learn. In a study published  in the journal NeuroImage, researchers at the  University of Freiburg and the University of Geneva show that even a nap is enough to reorganize connections between nerve cells so that new information can be stored more effectively.  The new study shows that a short sleep period can relieve the brain and put it back into a state of readiness to learn – a process that could be particularly beneficial for situations with high work load. The study examined 20 healthy young adults who either took a nap or stayed awake on two afternoons. The afternoon nap lasted on average 45 minutes.  The results showed that after the nap, the overall strength of synaptic connections in the brain was reduced – a sign of the restorative effect of sleep. At the same time, the brain's ability to form new connections was significantly improved. The brain was therefore better prepared for learning new content than after an equally long period of wakefulness. Screen time may increase body fat in children Ningbo University (China), January 15 2026 (News-Medical) A study published in Frontiers in Endocrinology reveals that higher screen time is associated with higher levels of body fat accumulation and less favorable obesity-related metabolic indicators in school-aged children, and that cardiorespiratory fitness can significantly influence this association. The study included a total of 1,286 third-grade students from six schools in Ningbo. Participants’ cardiorespiratory fitness was assessed using the 20-meter shuttle run test. Information on screen time, physical activity, and diet quality was obtained from self-reported questionnaires. The study analysis indicated that higher screen time is significantly associated with increased visceral fat accumulation, body fat mass index, and body fat percentage, and with lower cardiorespiratory fitness and slightly lower blood levels of HDL-C. The study found that participants with more than two hours of daily screen time exhibit significantly increased visceral fat, fat mass index, and fat percentage, and significantly reduced cardiorespiratory fitness compared to those with less than two hours of daily screen time. Simple dietary change may slow liver cancer in at-risk patients Rutgers University, January 29 2026 (Medical Xpress) People with compromised liver function may be able to reduce their risk of liver cancer or slow its progression with a simple dietary change: eating less protein. A Rutgers-led study has found that low-protein diets slowed liver tumor growth and cancer death in mice, uncovering a mechanism by which a liver's impaired waste-handling machinery can inadvertently fuel cancer. When people consume protein, the nitrogen can be converted into ammonia, a substance that's toxic to the body and brain. A healthy liver typically processes this ammonia into harmless urea, which is excreted via urine. The clinical observation that the liver's ammonia-handling machinery is usually impaired in liver cancer patients is decades old. Zong's team utilized a technique to induce liver tumors in mice without crippling the ammonia-disposal system. The researchers then used gene-editing tools to disable ammonia-processing enzymes in some—but not all. The results were striking: Mice with disabled enzymes and higher ammonia levels developed heavier tumor burdens and experienced a much faster rate of mortality than those with functioning systems. The researchers then tested a straightforward intervention: reducing dietary protein. Mice fed low-protein food exhibited dramatically slower tumor growth and lived significantly longer than those that received food with standard levels of protein BREAK   Introducing the Clips For Today  Sharmine Narwani : The Slow Strangling of Syria and Lebanon - 4:55  Inventing a pandemic - by Maryanne Demasi, PhD - MD REPORTS - full - 2:49    Did Covid mRNA boosters train the immune system to stand down? - full (Maryanne Demasi)  -2:38   Bryce Nickels on X: "-@R_H_Ebright explains why dangerous gain-of-function research should be BANNED https://t.co/2TaLBzzkU0" / X - full (Richard E Bright explains why dangerous gain of function research should be banned)  - 3:17

    1 hr
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Gary takes on the real issues that the mainstream media is afraid to tackle. Tune in to find out the latest about health news, healing, politics, and the economy.

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