The Human 5.0 Project

Ultimate Biohacker 10x
  • 5.0 (3)
  • NUTRITION
  • UPDATED SEMIWEEKLY

The Human 5.0 Project is the podcast where science meets self-optimization. Hosted by Ultimate Biohacker 10X, this show explores the real research, real data, and real dosing behind today’s most effective biohacking tools — from peptides, longevity molecules, and nootropics to recovery devices, lifestyle strategies, sleep optimization, training principles, and cutting-edge performance tech. Each episode breaks down complex biology into practical, actionable protocols you can use to improve energy, metabolism, cognition, and overall healthspan. No hype. No fluff. Just evidence-based insights for people who want to understand their bodies, upgrade their biology, and unlock their highest potential. If you’re ready to optimize your life one pathway at a time, you’re in the right place.

  1. 2H AGO

    2026 Hormone Optimization Guide: TRT/HRT Updates, At-Home Testing, Microplastics & Stress Stacks

    In 2026, “hormone optimization” is everywhere—but most of the conversation is either hype… or fear. In this episode, we build a post-pandemic, evidence-aware roadmap: what TRT/HRT actually is, what changed recently in labeling and clinical posture, how at-home saliva testing is evolving, what “3D-printed hormones” really means (and what it doesn’t), and how modern environmental stressors like microplastics may matter for endocrine health. We also cover smart “stacking” concepts—including adaptogens like ashwagandha—with the unsexy but essential safety reality: interactions, side effects, and why “more” isn’t always “better.”   DISCLAIMERS: Educational only; not medical advice. Hormone therapy is prescription medical care and should be managed by a licensed clinician with appropriate labs and follow-up. Supplements can cause side effects (including liver injury in rare cases). At-home tests can be useful for trends, but should not replace clinical diagnosis or treatment decisions.   Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   #HormoneOptimization #TRT #HRT #Testosterone #Menopause #BioidenticalHormones #Biohacking #Longevity #Healthspan #HumanPerformance #Microplastics #EndocrineHealth #Cortisol #SalivaTesting #Wearables #Ashwagandha #Adaptogens #StressManagement #SleepOptimization #LabTesting #EvidenceBased #TheHuman50Project #UltimateBiohacker10X

    11 min

  2. 1D AGO · VIDEO

    Biohacking for Dummies: What Is It and Why Start Now? (video)

    Upgrade your body like a smartphone app—no needles, no expensive gadgets, just free, high-ROI hacks that deliver 10X energy, focus, and resilience. In this beginner-friendly episode of The Human 5.0 Project, Ultimate Biohacker 10X breaks down what biohacking really is (and isn't), busts common myths, and gives you a simple 7-day starter plan using tools already on your phone. Whether you're crashing at 3 PM or struggling with sleep, this "Biohacking for Dummies" guide starts with the basics: hydration, movement, and mindset. No perfection required—just small updates for exponential results. Open: Why Upgrade Your Body Now? Intro to Human 5.0 Biohacking What Biohacking Actually Is (Smartphone Analogy) Myth Busting: What Biohacking ISN'T 3 Beginner Pillars: Hydration, Movement, Mindset 7-Day Starter Plan (Step-by-Step) Why Start Biohacking Today Closing Challenge Educational only—not medical advice. If you love this, subscribe for more 10X biohacking tips, hit the bell, and drop a comment: What's your first upgrade?   Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.

    10 min

  3. 1D AGO

    Biohacking for Dummies: What Is It and Why Start Now? (audio)

    Upgrade your body like a smartphone app—no needles, no expensive gadgets, just free, high-ROI hacks that deliver 10X energy, focus, and resilience. In this beginner-friendly episode of The Human 5.0 Project, Ultimate Biohacker 10X breaks down what biohacking really is (and isn't), busts common myths, and gives you a simple 7-day starter plan using tools already on your phone. Whether you're crashing at 3 PM or struggling with sleep, this "Biohacking for Dummies" guide starts with the basics: hydration, movement, and mindset. No perfection required—just small updates for exponential results. Open: Why Upgrade Your Body Now? Intro to Human 5.0 Biohacking What Biohacking Actually Is (Smartphone Analogy) Myth Busting: What Biohacking ISN'T 3 Beginner Pillars: Hydration, Movement, Mindset 7-Day Starter Plan (Step-by-Step) Why Start Biohacking Today Closing Challenge Educational only—not medical advice. If you love this, subscribe for more 10X biohacking tips, hit the bell, and drop a comment: What's your first upgrade?   Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   #BiohackingForBeginners #BiohackingBasics #Human5.0Procect #UltimateBiohacker10X #BiohackingTips #7DayBiohackPlan #UpgradeYourBody #EnergyHacks #FocusOptimization #Biohacking2026

    10 min

  4. 1D AGO

    Prostamax, Vesugen & Vesilute: Russian Peptides for Prostate & Bladder Health

    Prostamax vs Vesugen vs Vesilute: The Truth About Bioregulator Peptides (Evidence Breakdown)   Dive into the world of Russian bioregulator peptides with this episode of The Longevity Matrix! Host J.P. breaks down Prostamax (KEDP tetrapeptide), Vesugen (KED tripeptide), and Vesilute (ED dipeptide) – from herbal basics to epigenetic upgrades for prostate health, bladder function, vascular support, and anti-aging. If you're biohacking BPH, urinary issues, ED, or longevity, get the real data on mechanisms, protocols, and evidence gaps. No hype – just actionable insights from 2026 research. Intro: Prostate & Bladder Health Challenges Prostamax Herbal Blends – Evidence & Limitations Prostamax Peptide – Epigenetic Prostate Crusher Vesugen – Systemic Anti-Aging & Vascular Vitalizer Vesilute – Bladder-Specific Bioregulator Synthesis: Stacks, Protocols & Practical Hacks What are bioregulator peptides? How do they target gene expression for inflammation reduction and tissue repair? We cover preclinical rat models, human cell studies, and practitioner protocols – including stacking Prostamax peptide with Vesugen for vascular synergy or Vesilute for pelvic floor optimization. From Saw Palmetto combos to Khavinson's chromatin hacks, this is your guide to beyond-basics biohacking. DISCLAIMER: Educational content only – not medical advice. Peptides are experimental; consult a healthcare professional before use. Not FDA-approved. Source from reputable labs and monitor biomarkers like PSA and CRP.   Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   #Prostamax #Vesugen #Vesilute #BioregulatorPeptides #ProstateHealth #BladderHealth #RussianPeptides #Biohacking #Longevity #Epigenetics #BPH #AntiAging #PeptideTherapy #KhavinsonPeptides #UrinaryHealth #VascularHealth #TheLongevityMatrix #HealthOptimization #EvidenceBased #GeneExpression #PelvicFloor #EDTreatment #Biohacker #ultimatebiohacker10x#Thehuman5.0project

    12 min

  5. 1D AGO

    Experimental Lewy Body Dementia Treatments 2026: Zervimesine, Cerebrolysin, Stem Cells & Exosomes

    Out-of-the-Box Treatments for Early Lewy Body Dementia (Full Case Review) Discover the most discussed experimental and regenerative options for early Lewy body dementia (LBD / DLB) in this 2026 case review. A 76-year-old man with occasional hallucinations and minimal comorbidities — what realistic “fringe-to-frontline” approaches are families actually pursuing right now? In this episode of Out of the Box we rank the options by current evidence, safety, and access: ✅ Zervimesine (CT1812) – the oral drug with published Phase 2 SHIMMER trial data showing signals on hallucinations, cognitive fluctuations, daily function, and motor symptoms ✅ Cerebrolysin IV protocols used in Mexico & Germany (doses, duration, real-world clinic combos) ✅ Allogeneic mesenchymal stem cells (MSC) + Cerebrolysin combination packages ✅ Nebulized (inhaled) exosomes – the newest non-invasive option ✅ Leaky gut / microbiome optimization ✅ Semax, Noopept, L-serine, and other peptides We give honest 2026 reality checks: what is supported by published data, what is still highly experimental, and how to vet international clinics if you’re willing to travel.   This is educational content only — not medical advice. Nothing discussed is proven to reverse or cure Lewy body dementia. Always consult your neurologist before considering any experimental treatment, clinical trial, or medical tourism.   Resources mentioned: • Cognition Therapeutics (Zervimesine / CT1812) → cogrx.com • ClinicalTrials.gov search: “dementia with Lewy bodies” • SHIMMER trial publication (Alzheimer’s & Dementia, 2025/2026)   If you or a loved one are exploring options beyond standard care, drop a comment: What treatment are you most curious about? Subscribe for more deep-dive case reviews on neurodegenerative diseases, regenerative medicine, and out-of-the-box topics.   Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.       #LewyBodyDementia #LBD #DementiaTreatment #Zervimesine #CT1812 #Cerebrolysin #StemCellTherapy #ExosomeTherapy #NebulizedExosomes #RegenerativeMedicine #MedicalTourism #ExperimentalTreatment #LewyBody #DLB #DementiaResearch #Neurodegeneration #BrainHealth #Alzheimers #ParkinsonsDementia

    13 min

  6. 2D AGO

    AOD-9604: The REAL Science on This Fat-Burning Peptide (Trials, GRAS, FDA 2024)

    You wake up at 5:47 a.m., lights on, shirt off… and that lower-belly fat is still mocking you. You’ve optimized sleep, training, macros, GLP-1s, fasted cardio, cold plunges — yet the scale won’t move. Then the peptide groups light up: “AOD-9604. The actual fat-burning fragment of HGH. Melts visceral fat. No IGF-1 spike. No water retention. No b******t.” Is it the real signal… or is the hype hallucinating? In this no-BS breakdown we rip open:   The full 16-amino-acid C-terminal fragment story $50 million pharma R&D, 6 human trials, 925 subjects 2005 Phase 2b result (2.8 kg vs 0.8 kg placebo) and why the larger trial failed Exact mechanism: lipolysis + lipogenesis inhibition 2012 GRAS self-affirmation for oral use December 4, 2024 FDA PCAC meeting — Dr. Edwin Lee’s testimony + unanimous “No” on compounding Research dosing, cycling, and 10X stacking protocols Safety data, sourcing risks, WADA ban   No affiliate links. No bro-science. Just the raw data.   The mirror test (intro) Mandatory disclaimer What AOD-9604 actually is Mechanism – no fluff The human trials – the real story GRAS status – the 2012 twist December 2024 FDA reality check Dosing & cycling – research protocols only 10X stacking strategies Safety – real talk AOD-9604 vs. the competition Final verdict – no cope Your 5-point checklist Outro Strong Disclaimer AOD-9604 is research-grade only. Never FDA-approved for any human use. Sold strictly for laboratory research — “not for human consumption.” Human use is experimental, carries unknown long-term risks, sourcing dangers, and is banned by WADA. This video is for educational and entertainment purposes only. Consult a licensed physician, get bloodwork, and comply with all laws. Citations: • Heffernan et al., Endocrinology 2001 • Wittert et al., Diabetes 2005 • Stier et al., J Endocrinol Metab 2013 • Calzada GRAS announcement, June 2012 • FDA PCAC public minutes, Dec 4 2024 Drop your biggest question about AOD-9604 in the comments — I read every single one.   Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   #AOD9604 #AOD9604Peptide #FatLossPeptide #PeptideTherapy #Biohacking #StubbornFat #VisceralFat #GRAS #FDAUpdate #PeptideStacking #HumanGrowthHormone #WeightLossScience #UltimateBiohacker #Human5.0project #ResearchPeptides

    14 min

  7. 3D AGO

    HRV Truth Serum: Which Wearables Are Accurate at Night? (Oura vs WHOOP vs Garmin vs Polar)

    Best Wearable for HRV? New Study Validates Oura, WHOOP, Garmin & Polar vs ECG (Sleep Data)   Is your nightly HRV actually real… or just wearable noise?   A new open-access validation study in Physiological Reports (Aug 2025) compared nocturnal resting heart rate (RHR) and heart rate variability (HRV, RMSSD) from five popular consumer wearables against an ECG reference (Polar H10 chest strap) across 536 nights in real-world home sleep conditions (13 healthy adults).   Devices tested:   Oura Ring Gen 3   Oura Ring Gen 4   WHOOP 4.0   Garmin Fenix 6   Polar Grit X Pro   Key takeaways (biohacker translation): RHR was generally solid across devices during sleep (Oura strongest). HRV is where accuracy separates: Oura (Gen 4 & Gen 3) came out closest to ECG, WHOOP was acceptable for trends, while Garmin and Polar showed lower concordance for HRV in this dataset. The real play isn’t obsessing over one night — it’s using trend tracking (7–14 day averages) and making decisions off patterns, not vibes.   Educational only — not medical advice. Wearables aren’t diagnostic tools.   Comment HRV with what device you use and whether your numbers match how you feel.   Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.   #Human50Project #HRV #RestingHeartRate #Wearables #Biohacking #Recovery#OuraRing #Whoop #GarminFenix #PolarGritXPro #PolarH10 #SleepTracking#Physiology #SportsScience#Training#HeartRateVariability#SignalVsNoise #UltimateBiohacker10X

    9 min

  8. 3D AGO

    CGM for Drugs? New Patch Tracks Vancomycin Every 5 Minutes — Could Peptides Be Next?

    What if your skin could show a medication’s concentration curve in real time—updated every 5 minutes?   A pilot clinical trial published in Nature Biotechnology (Feb 2026) tested a wearable microneedle patch that continuously measures vancomycin levels in dermal interstitial fluid using electrochemical aptamer-based sensors. The patch was reported as safe and nearly pain-free, captured high-resolution trends, and revealed pharmacokinetic dynamics that sparse blood draws can miss—though sensor degradation limited the most robust analysis to roughly the first ~12 hours.   In this Human 5.0 Project episode, we break down the tech like grown-ups:   What the patch is and how it works (microneedles + aptamer sensors) Why therapeutic drug monitoring today is still “rear-view mirror medicine” The CGM parallel: why continuous trends beat snapshots The real limitations (small pilot, drift, healthy volunteers) BONUS (Peptide Future Segment): Could this platform ever monitor peptides/bioregulators? We talk what’s plausible, what’s hard, and why “continuous chemistry monitoring” is the next frontier—without overpromising.   Educational only — not medical advice. Do not self-medicate. For meds, hormones, or peptides, consult a qualified clinician.   🔥 Subscribe for no-BS biohacking & longevity drops Follow on IG @Ultimatebiohacker10X For more longevity insights and protocols, check out biohackerdepot.com – your go-to resource for cutting-edge health optimization strategies. And if you're sourcing research peptides , peptidesphere.com has a curated selection of peptides and bioregulators with detailed info on quality and applications.     #Human50Project #Biohacking #PrecisionMedicine #Wearables #Microneedles #Aptamer #TherapeuticDrugMonitoring #Vancomycin #Pharmacokinetics #PrecisionDosing #ContinuousMonitoring #CGM #HealthTech #Peptides #Bioregulators #Longevity #SignalVsNoise #UltimateBiohacker10X

    9 min
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Ratings & Reviews

5
out of 5
3 Ratings

About

The Human 5.0 Project is the podcast where science meets self-optimization. Hosted by Ultimate Biohacker 10X, this show explores the real research, real data, and real dosing behind today’s most effective biohacking tools — from peptides, longevity molecules, and nootropics to recovery devices, lifestyle strategies, sleep optimization, training principles, and cutting-edge performance tech. Each episode breaks down complex biology into practical, actionable protocols you can use to improve energy, metabolism, cognition, and overall healthspan. No hype. No fluff. Just evidence-based insights for people who want to understand their bodies, upgrade their biology, and unlock their highest potential. If you’re ready to optimize your life one pathway at a time, you’re in the right place.

Information

  • Creator
    Ultimate Biohacker 10x
  • Years Active
    2025 - 2026
  • Episodes
    111
  • Rating
    Explicit
  • Copyright
    © Copyright 2025 All rights reserved.
  • Show Website
    The Human 5.0 Project

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