In the final episode of Prevention Unpacked with Dr. Zili Sloboda: Vision, Legacy & The Future of Prevention, the conversation looks ahead and brings the series full circle. Drawing on decades of global experience, Dr. Zili Sloboda shares her vision for where prevention must go over the next 10 to 20 years. She reflects on what it would mean for prevention to be fully recognised as a profession, embedded across health, education, and social systems, and guided by a true culture of prevention rather than short-term solutions. The episode explores emerging frontiers shaping the future of the field, including digital environments, climate change, misinformation, neuroscience, and equity. Dr. Sloboda speaks candidly about the need for stronger integration between research and practice, new training pathways, and leadership grounded in respect, listening, and collaboration. As the conversation turns to legacy, Dr. Sloboda reflects on the moments that have mattered most in her career, the role of global networks such as ISSUP and ICUDDR, and what gives her hope for the next generation of prevention professionals. The series closes with a powerful reminder that prevention is not a static outcome, but a living, evolving process carried forward by people, partnerships, and shared purpose. Featured Voices Host – A/Prof. Goodman Sibeko ISSUP Global Scientific Advisor. Head of Addiction Psychiatry, University of Cape Town. LinkedIn: goodmansibeko Twitter/X: @profgsibeko Guest – Dr Zili Sloboda Dr Zili Sloboda is a global leader in prevention science whose work has shaped evidence-based prevention practice worldwide. Time Stamps [00:00] – Introduction [00:35] – The Future of Prevention Over the Next 10–20 Years [02:22] – Integrating Prevention into Health and Social Systems [04:46] – Emerging Challenges: Digital Change, Climate, and Equity [06:45] – Leadership Philosophy in Global Prevention Work [09:41] – Professional Collaboration and Field Connectivity [12:03] – Advice for Early and Mid-Career Prevention Professionals [15:10] – Career Reflections and Defining Achievements [18:08] – Hope for the Future of Prevention [19:09] – Closing Reflections About the ISSUP Exchange The ISSUP Exchange podcast series explores the evolution of responses to the challenges of substance use—from research and training to ethics, quality standards and evidence-based practice. We connect the dots so you can see the big picture. Explore more episodes and join the ISSUP podcast community here>>> About ISSUP ISSUP is a global network that unites, connects, and shares knowledge across the substance use prevention, treatment, and recovery support workforce. Our mission is to make our members’ work as effective as possible—by providing access to training, resources, and a vibrant professional community.