The S2G Podcast

S2G Investments

This is the S2G Podcast, where we talk to business leaders, investors, policymakers, and thought leaders who have a transformative vision for the future. We’ll explore how their experiences and perspectives offer lessons into scaling the food, agriculture, oceans, and energy transitions. 

  1. Cutting Through the Noise of a Changing World with Gayle Tzemach Lemmon

    12H AGO

    Cutting Through the Noise of a Changing World with Gayle Tzemach Lemmon

    In this episode, Gayle Tzemach Lemmon joins Sanjeev Krishnan for a conversation about resilience and opportunity in a world defined by volatility. Gayle brings a rare breadth of experience as a builder, early-stage advisor, PE portfolio strategist, foreign policy veteran, former political reporter, investor, and three-time New York Times best-selling author on geopolitical topics, with a front-row seat to multiple moments of global transition. Together, they dig into Gayle’s idea of a “triangle of opportunity” at the intersection of energy, artificial intelligence, and geopolitics, and why those forces are increasingly shaping how societies and economies evolve. They also talk about how to separate signal from noise in today’s policy landscape and what business leaders can learn from entrepreneurs operating in the most fragile and constrained environments. It’s a grounded, clear-eyed conversation about how to think, communicate, and build when the rules are constantly changing.  Key Takeaways: Economics and politics can’t be separated anymore. Gayle explains how political forces quietly shape markets, capital flows, and business outcomes, whether leaders want to admit it or not. She argues this is a moment of rising political corners and borders.Fairness has become a defining theme of this era. From labor to capital markets, Sanjeev and Gayle discuss why perceptions of who benefits and who doesn’t are influencing trust, policy, and long-term stability. Homogeneous thinking is a real business risk in periods of rapid change. Gayle argues that value is increasingly created by people who can move across disciplines and see congruities that others may miss.AI, energy, and geopolitics are tightly linked. Sanjeev and Gayle explore how each of these forces shapes the others, and decisions in one area increasingly ripple and resonate across the rest in sometimes unpredictable ways.Clear, genuine storytelling is no longer optional. According to Gayle, in a crowded, noisy investment landscape, leaders and companies that can communicate simply and authentically are more likely to earn trust and endure.You can purchase Gayle’s first book, “The Dressmaker of Khair Khana,” referenced in this episode here: https://www.amazon.com/Dressmaker-Khair-Khana-Remarkable-Everything/dp/0061732478  This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures.

    43 min
  2. The Food as Health Solution Set

    FEB 19

    The Food as Health Solution Set

    In this bonus episode, we’re bringing together seven CEOs across the S2G portfolio to explore what it actually looks like to make food as health a reality within the U.S. healthcare system. In a previous episode, we focused on the obstacles and investor opportunity, so this week we’re steering the conversation to the solutions already being built and tested in the market. Across clinical nutrition, oncology, care coordination, meal delivery, and life-science AI, leaders from Mend, Big Bold Health, Pyx Health, Mealogic, NourishedRx, Sōlaria Biō, and Brightseed describe how they’re reframing healthcare through food-based solutions. The discussion spans new scientific frameworks for understanding food as a complex, multi-target intervention, the importance of rigorous clinical evidence and FDA pathways, the realities of reimbursement and payer incentives, and the challenge of patient adherence. Woven together, these CEOs create a blueprint for a healthcare system where food-based solutions are preventative, scalable, and central rather than peripheral. Links: The Food as Health Opportunity white paper Big Bold Health Brightseed Mealogic Mend NourishedRx Pyx Health Sōlaria Biō This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures.

    30 min
  3. The Price of Transportation in an Electrifying World

    FEB 12

    The Price of Transportation in an Electrifying World

    Electric vehicles have become a bit of a cultural lightning rod, but behind the headlines, there’s a lot to be excited about. In this episode, Sanjeev sits down with Mitra CEO Galina Russell, S2G Principal Marisa Sweeney, and Clean Tech Strategy Advisors’ Managing Partner Anna Demeo to talk about the state of the EV market and where the opportunities lie today. Mitra, a recent investment from S2G’s Special Opportunities team, helps small and midsize commercial fleets go electric by bundling vehicles and charging into a single, simple offering, delivering savings almost immediately with no upfront cost. The conversation explores how EVs could make the power grid more flexible rather than more strained, why electrification is closely tied to the future of autonomous vehicles, how China’s rapid scaling of EVs and charging infrastructure is reshaping global markets, and why financing remains one of the biggest bottlenecks to broader adoption. It’s a clear, practical look at where the EV story is headed and what it will take to get there.   Chapters:  03:24 - The State of Transportation 05:33 - Cultural Aspects of EV Adoption 09:00 - EV Industry Investment Landscape 11:53 - China's Role in the EV Market 14:42 - EVs and the Future of the Grid 18:49 - Physical AI and Autonomous Vehicles 21:37 - Mitra's Approach to Fleet Electrification 27:22 - Fit for Purpose Capital in EVs 33:17 - Bringing in More Capital 40:22 - Future Predictions for EV Adoption This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures.

    46 min
  4. Healthcare Costs Keep Rising. Food Could Be a Fix.

    JAN 29

    Healthcare Costs Keep Rising. Food Could Be a Fix.

    If diet is a major driver of chronic disease, and chronic disease is driving healthcare costs, why are our food and healthcare systems still so separate? And what would change if they weren’t? In this episode, S2G’s Sanjeev Krishnan and Dan Ripma use our new Food as Health white paper as a jumping-off point to unpack what “food as health” really means and why a system that keeps getting more expensive without making people healthier is reaching its limits. They explore the tension between medical ethics and financial reality, the disconnect between hunger and nutrition, and why food has to be part of any serious conversation about cost and prevention. Then we zoom out to what this means for investors and how healthcare economics reshape the opportunity in food. Ultimately, this is a conversation about how food could move from being part of the problem to becoming one of the most powerful tools we have to change the economics and the outcomes of our healthcare system. Chapters:  3:06: Nutrition's Identity Crisis 5:58: The Hippocratic oath vs. The Bond Market 8:03: Food as Health as Strategic Infrastructure  10:48: Economic Implications of Healthcare Costs 12:41: Challenges in Policy and Nutrition 16:24: S2G’s Food as Health Strategy 18:58: Clinical and Economic Evidence 29:04: Investor Perspective on Food as Health This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures.

    40 min
  5. S2G's Managing Partners Predict a Year of Complexity and Opportunity

    JAN 15

    S2G's Managing Partners Predict a Year of Complexity and Opportunity

    What if the biggest risk right now isn’t getting the answers wrong, but asking the wrong questions? In our Season 3 kickoff, all three S2G Managing Partners come together to unpack a moment defined by volatility, AI acceleration, geopolitics, and a rising cost of capital. They explore why constraints are no longer a weakness but a competitive advantage, and how affordability, resilience, and execution matter more than hype. From private markets and global debt to AI, demographics, and the “Age of Adaptation,” Sanjeev Krishnan, Chuck Templeton, and Aaron Rudberg help frame the macro and micro playbook for what it will take to build businesses in 2026. It’s a sharp, honest look at where to find the opportunity when the rules keep changing. Key Takeaways: Constraints create winners. The MPs discuss how tighter capital, higher rates, and geopolitical friction favor disciplined builders and sober investors.AI is shifting from experiment to ROI. The conversation reveals how 2026 is about using AI to drive real productivity, margin improvement, and “cheaper, faster, better” outcomes.A human edge still matters. While AI is powerful, Chuck argues it’s human judgment, experience, and the ability to guide it that ultimately turn technology into a real advantage.Resilience beats efficiency in a volatile world. According to the MPs, the future belongs to companies with durable moats, flexible supply chains, and business models built to survive uncertainty.The right questions matter more than ever. According to Sanjeev, old assumptions about capital, risk, and growth no longer hold. Success now starts with rethinking first principles. This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures.

    39 min
  6. “Everybody in the Pool’: Cleaning Up the Textiles Industry With Matter Filters

    12/18/2025

    “Everybody in the Pool’: Cleaning Up the Textiles Industry With Matter Filters

    In this special episode-share, we team up with Everybody in the Pool to spotlight the urgent and fast-growing challenge of microplastic pollution and the breakthrough filtration technology designed to tackle it at scale. Longtime tech and business journalist Molly Wood speaks with Adam Root, Matter’s founder and CEO, about how microfibers from everyday laundry to industrial textile production have become one of the largest sources of ocean microplastics, and why the textile industry is facing mounting pressure from regulators, retailers, and consumers to address the issue. Matter’s regenerative filtration system offers a practical, modular solution that can be deployed across home appliances and industrial facilities, delivering both measurable environmental benefits and meaningful cost savings. It’s a forward-looking conversation about how infrastructure-level innovation can reshape a legacy industry and build cleaner, more resilient water systems worldwide. Links: Matter Industries Website: https://matter.industries/  Adam Root LinkedIn All episodes: https://www.everybodyinthepool.com/  Subscribe to the Everybody in the Pool newsletter: https://www.mollywood.co/  Become a member and get an ad-free version of the podcast: https://everybodyinthepool.supercast.com/  This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures.

    39 min
  7. How AI for Agriculture Can Outsmart Volatility

    12/04/2025

    How AI for Agriculture Can Outsmart Volatility

    Food prices keep climbing. Farmers are facing shrinking profit margins. Can AI really fix both, or is it just another Silicon Valley hype cycle? With all the talk about an “AI bubble,” we bring you a conversation about how AI is already shaping farm viability today and what it could mean for your grocery bill tomorrow. In this episode of the S2G Podcast, Chuck Templeton sits down with Shail Khiyara, CEO of decision-intelligence company SWARM, and Adam Greenberg, CEO of greenhouse OS provider IUNU, to unpack how AI is being used today across fields, greenhouses, and supply chains. They dig into how digital twins, sensors, and machine vision can turn volatility into an advantage, cut waste, and boost margins for growers while helping keep food more affordable for consumers. They discuss what it really takes to drive AI adoption in a sector built on thin margins and healthy skepticism, and how partnerships and long-term purchase agreements could reshape the economics of fresh, local food. Whether you’re an AI superfan or a skeptic, an ag insider, or just someone worried about your grocery bill, this conversation offers a grounded look at what a smarter, continuously learning food system might actually look like in practice. Chapters:  03:55 SWARM and IUNU’s AI Solutions 08:59 Challenges and Mindset Shifts in AI Adoption 11:50 AI's Impact on Decision Making in Agriculture 14:10 Accelerating AI Adoption in Agriculture 25:29 The Cognitive Grid: AI's Future in Agriculture 27:31 Economic Impacts of AI on Farmers 32:08 Successful Partnerships and Future Outlook 36:38 Advice for Farmers on AI Adoption This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures.

    40 min

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This is the S2G Podcast, where we talk to business leaders, investors, policymakers, and thought leaders who have a transformative vision for the future. We’ll explore how their experiences and perspectives offer lessons into scaling the food, agriculture, oceans, and energy transitions. 

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