The Trip Lab

Mary Ella Wood, DO

Welcome to The Trip Lab, kitchen table conversations about integrative medicine and psychedelics with your host and attending physician, Dr. Mary Ella Wood. Taking an evidenced-based approach, we will break down the latest research, interview leaders in the field, and answer all the questions that don't often get brought up in the doctor's office. Instagram: @thetriplabpodcast - Email: thetriplabpodcast@gmail.com

  1. 12/22/2025

    #19 – DEEP DIVE SERIES: Hyperlipidemia (Why Cholesterol and Statins Aren’t the Villains You Think They Are)

    In this Deep Dive episode of The Trip Lab, we unpack hyperlipidemia (high cholesterol) beyond the oversimplified “LDL bad, HDL good” narrative. We also take a clear-eyed look at the most common concerns people have about statins, what the evidence actually shows, and where these medications fit—and don’t fit—within a thoughtful, individualized approach to cardiovascular risk. From there, we explore integrative strategies for managing elevated cholesterol and why, for many patients, lifestyle, metabolic health, and inflammation-targeted interventions may be more effective than medications alone. In this episode, we discuss: Why cholesterol is biologically essential and not inherently pathologicalThe limitations of relying on LDL alone to assess cardiovascular riskHow inflammation, insulin resistance, genetics, hormones, and lifestyle influence lipid metabolismWhen elevated cholesterol truly signals disease—and when it may reflect a compensatory or adaptive responseThe role of advanced markers such as ApoB, Lp(a), hsCRP and CAC scoresWhy risk stratification—not fear-based medicine—should guide clinical decision-makingWhat statins can (and cannot do) and we break down the concerns people have with themWhy integrative approaches (nutrition, exercise, herbal options and mind-body medicine) truly treat the root cause of diseaseThis episode is for clinicians, patients, and anyone looking to move beyond simplistic cholesterol narratives toward a more nuanced, evidence-based understanding of cardiovascular health.

    39 min
  2. 08/06/2025

    #18 — Psychedelics and the Feminine: Healing Cycles, Hormones, and the Womb

    In this season 2 opening episode of The Trip Lab, I return from maternity leave with a deeply personal exploration of how psychedelic experiences mirror one of the most profound transitions in a woman’s life: motherhood. From the sudden crash of postpartum hormones to the full dissolution of identity and the slow reconstruction of self, I reflect on how becoming a mother felt strikingly similar to a psychedelic journey — raw, disorienting, expansive, and sacred. We dive into the neuroscience of hormonal transitions, ego death, and neuroplasticity — exploring how estrogen, the Default Mode Network, and maternal brain remodeling all connect to the psychedelic experience. We also examine the often-overlooked wisdom of the menstrual cycle, the energetic sensitivity of pregnancy, and why the womb may be one of the most powerful maps for understanding transformation and healing. This episode is for anyone curious about the intersection of psychedelics and the feminine — whether you’ve given birth, are hoping to one day, or simply want to understand how cycles, hormones, and identity shifts can open portals into deeper layers of self. Topics include: Postpartum as ego death and rebirthEstrogen, neuroplasticity, and the psychedelic brainPsychedelics and the Default Mode Network in womenHormonal cycles and their influence on medicine journeysAncestral wisdom, womb intelligence, and the sacred feminine

    18 min
  3. 04/27/2023

    #14 — Integrative Approaches for Anxiety & Depression

    This episode is going to be a high level overview over all of the primary causes of anxiety and depression, and integrative approaches to treat them. Anxiety and depression is a lot more complicated than just writing a script for sertraline or recommending therapy. These disorders definitely have a psychological component that can stem from chemical imbalances in the brain... but other causes include nutritional deficiencies, inflammation and adrenal fatigue, poor sleep hygiene, not exercising enough, improper use of medications or underlying medical causes like hormonal fluctuations or imbalances, thyroid disorders and anemia. We will dive deeper into these causes and go over traditional medical approaches as well as evidenced-based complementary treatments like psychedelics, nutrition and mind-body medicine. Also in this episode I introduce my NEW professional website where you can learn about medical services I will be offering at the Osher Center for Integrative Medicine at Northwestern in Chicago, IL. Additionally, I am now offering yoga & meditation classes, spiritual practices like tarot and astrology, and a whole lot more. Check out my website at drmaryellawood.com. This course is a preview of an upcoming course I am developing called 'Integrative Approaches for Anxiety & Depression.' In this course we dive deeper into what is discussed in this podcast, break down the science in an easy to understand more, look at more specific treatment options, and help you understand YOUR body and your personal  mental health journey. The course also works well as a crash course for healthcare providers that want to learn more about integrative medicine treatment options that they can prescribe to their patients. Website: drmaryellawood.com Instagram: @drmaryella YouTube Channel: Dr. Mary Ella Podcast Instagram: @thetriplabpodcast

    38 min

Ratings & Reviews

5
out of 5
9 Ratings

About

Welcome to The Trip Lab, kitchen table conversations about integrative medicine and psychedelics with your host and attending physician, Dr. Mary Ella Wood. Taking an evidenced-based approach, we will break down the latest research, interview leaders in the field, and answer all the questions that don't often get brought up in the doctor's office. Instagram: @thetriplabpodcast - Email: thetriplabpodcast@gmail.com