When a child suddenly develops anxiety, rage, tics, restrictive eating, or emotional volatility, the system rushes to label and medicate it. But what if those behaviors aren't psychological at all? What if they're inflammatory? What if the brain isn't "misfiring," but reacting loudly to an immune system that's overwhelmed, dysregulated, and unable to turn itself off? In my work, I've watched this pattern repeat over and over. Kids change "overnight," parents think "I've lost my child," and the healthcare system rarely asks the most important question: what happened before the behavior changed? In today's world, children are exposed to environmental toxins, infections, immune stress, chronic inflammation, and genetic vulnerabilities. These lead to the very common sudden behavioral and emotional changes we're seeing in so many young people. And childhood immune dysregulation doesn't stay in childhood. Untreated neuroinflammation can follow kids into adolescence, adulthood, and eventually shape entire family trees. How do we reduce the physical stress driving these changes in so many children and families? What's actually happening beneath the surface of conditions like PANS/PANDAS, eczema, autism, anxiety, and sudden behavioral regression? To unpack this, I'm joined by Dr. Paula Kruppstadt, a board-certified pediatrician and functional medicine physician who works with some of the most complex pediatric cases. She explains what's driving these sudden changes, why standard approaches often miss it, and what actually helps kids stabilize and recover. Things You'll Learn In This Episode When behavior is actually a physical issue Sudden mood swings, anxiety, rage, tics, or regression are often treated as "behavior problems." What if it's a sign that inflammation or infection is affecting how your child feels and acts? Why "it happened overnight" actually matters If your child seemed fine and then suddenly wasn't, that change isn't random. What can abrupt shifts tell you about underlying health issues that often get missed? Food programs immunity How can common foods like gluten, dairy, dyes, and additives quietly contribute to eczema, anxiety, and emotional ups and downs, even when kids seem otherwise healthy? A more precise way to vaccinate Most parents are told to stick to the routine vaccine schedule, but that can push a child's system too hard, too fast. How do we give kids vaccines in a way that protects immunity without unnecessarily adding inflammatory load? PS. If you enjoy the show, remember to leave a review on your favorite podcast app! Reviews help the podcast reach a wider audience and help more people. About the Guest Dr. Paula Kruppstadt is the founder, CEO, and Medical Provider Team Leader for Hope for Healing. She graduated in 1990 from the University of Texas Health Science Center at San Antonio and completed her pediatric internship and residency at William Beaumont Army Medical Center in El Paso in 1993. She promptly earned her Board Certification from the American Board of Pediatrics in 1993, and she is also a Fellow of the American Academy of Pediatrics. She served as a U.S. Army pediatrician at Ft Hood, Texas, and then relocated to The Woodlands, Texas, in 1995. She has since worked as a general pediatrician in various venues, including Texas Children's Pediatrics and Texas Children's Urgent Care. Dr. Kruppstadt also served as a pediatric hospitalist and faculty member for Baylor College of Medicine at St. Luke's Hospital in The Woodlands, Texas. Dr. Kruppstadt is a Certified Practitioner of Functional Medicine by The Institute for Functional Medicine—IFMCP. She is one of the few board-certified pediatricians in the world who are certified IFMCP. Because she is an expert on PANS/PANDAS, Texas Governor Greg Abbott appointed her to be a member of the Pediatric Acute-onset Neuropsychiatric Syndrome Advisory Council. The Council advises the commission and the Texas legislature on research, diagnosis, treatment, and education related to pediatric acute-onset neuropsychiatric syndrome. Dr. Kruppstadt is the mother of four daughters, who have all worked at Hope for Healing, and she has two grandsons. She is married to Tom Kruppstadt, JD, who serves as COO/CFO and General Counsel for Hope for Healing. To learn more, visit https://get2theroot.com/. You can also schedule a free discovery call or buy a genetic panel here. About Your Host Steve Hoffart is an award-winning pharmacist, entrepreneur, speaker and podcaster. As the visionary founder of Magnolia Pharmacy, Steve saw a need for a more personal pharmacy that could make a bigger impact. Today, Steve and his team of experts deliver on that promise, working with patients and their physicians to solve medication problems and offer personalized solutions to achieve better health and wellness. As host of The Trusted Pharmacist podcast and through his combined reach of over 1M on social media, Steve shares actionable advice on nutrition, supplements, and wellness strategies while advocating for meaningful change in healthcare. Stay Ahead with Steve the Pharmacist! Loving the show? Want more insights into how your body works? Head over to TheTrustedPharmacist.com and sign up with your email! You'll get the latest episodes, plus exclusive health tips to help you take charge of your wellness. Don't miss out – join me today!
