This Is Only A Test

Halteres Associates
  • 5,0 (2)
  • БИОНАУКИ

A video series covering the interesting stories in the history of diagnostics, disease, health technology, medtech charlatans, and more. Hosted by Mickey Urdea, presented by Halteres Associates. You can also watch this podcast on YouTube: https://www.youtube.com/playlist?list=PLz6idmkQtRiaGzpnOJZqpuksfpE0f_SrQ

  1. Ep. 5: "Using The Right Tool!" - This Is Only A Test

    17 МАР.

    Ep. 5: "Using The Right Tool!" - This Is Only A Test

    On Episode 5 of “This Is Only A Test,” Mickey Urdea takes on one of the most fundamental challenges in modern diagnostics: using the right tool for the job. As scientists gain deeper insight into the complexities of human biology - from the genome and transcriptome to proteins, metabolites, and entire cell populations - the technologies used to study them are evolving just as quickly. Choosing the correct technology at the right stage can mean the difference between a promising discovery and a successful clinical diagnostic. In this episode, Mickey walks through the journey from biomarker discovery to validation and ultimately clinical diagnostics, exploring the platforms that power each step. Along the way, he compares the strengths and limitations of tools like NGS, advanced immunoassays, mass spectrometry, and spatial biology techniques. From massive sequencing projects and the Human Cell Atlas to multiplex protein assays and single-cell metabolomics, researchers are navigating an explosion of biological data while still uncovering how much we have yet to learn about human disease. So before you pick up a pipette, make sure you’ve chosen the right tool. Join Mickey for a tour through the technologies shaping the future of biomarker science on “Using The Right Tool!”

    47 мин.
  2. Ep. 4: "Getting Our Heads Around TBI!"

    24.11.2025

    Ep. 4: "Getting Our Heads Around TBI!"

    On this episode of "This Is Only A Test", Mickey Urdea is banging his head against the issue of traumatic brain injuries, or TBI! Globally, 69 million people suffer traumatic brain injuries every year, yet there have been very few successful quantifiable diagnostics available aside from field tests for noticeable symptoms. Mickey goes deep into the known diagnosable symptoms of TBI, the FDA-approved tests in the field, and the latest research on acetylated tau proteins as a surrogate endpoint. Now strap your helmet on and brace for impact on "Getting Our Heads Around TBI!"

    28 мин.
  3. Ep. 3: "Learning To Live With The Fungus Among Us!"

    18.08.2025

    Ep. 3: "Learning To Live With The Fungus Among Us!"

    On the third episode of This Is Only A Test, Mickey Urdea is breaking the mold to talk to you about mold! Mycology, the study of the Kingdom of Fungi, might not get the spotlight as often as Animals or Plants (heck, maybe even less than some Protists) but the powerful Fungus plays a key cog in the cycle of life on Earth, especially in regard to their roles as decomposers (Wolfgang Amadeus Moldzart, anyone?) and as food fermenters. But don't break out the Roquefort just yet, as mold can also cause debilitating disease in humans, from the emerging fungus C. auris, which can cause severe multidrug-resistant illness in hospitalized patients, to ergotism, a poisoning predominantly caused by infected rye which can cause gangrenous symptoms (think a Pieter Bruegel painting) and delirious hallucinations that border on madness (think a Hieronymus Bosch painting); in fact, some hypothesize that ergot poisoning can explain away the Dancing Plague of 1518, and maybe even the Salem Witch Trials! Mickey covers it all, as well as the latest diagnostic technologies and methodologies which are helping to test and treat neglected mycological diseases. So douse your tempeh in soy sauce and grab a bottle of Chianti, it's time for "Learning To Live With The Fungus Among Us!"

    36 мин.
  4. Ep. 2: “Gaining An Aptitude For Aptamers!”

    24.06.2025

    Ep. 2: “Gaining An Aptitude For Aptamers!”

    On Episode 2 of "This Is Only A Test", Mickey Urdea is thrilled to be finally talking about APTAMERS! Aptamers are generally defined as oligomers of artificial ssDNA, RNA, or XNA which bind a specific target molecule or family or target molecules, and despite some Nobel Prize-winning work in the field, they have been underutilized for immunoassay development – until now! If Mickey has his way, you will walk away from this episode champing at the bit to get your hands on some aptamers. So please enjoy this overview of the development of the use of aptamers in immunoassays, the latest innovations and breakthroughs in those methodologies, and the determined companies working to harness those technologies. Get rapt to be apt at aptamers! Click HERE for all the slides presented in this episode.

    48 мин.
  5. Ep. 1: "Moving To The Rhythm of Algorithms!"

    07.05.2025

    Ep. 1: "Moving To The Rhythm of Algorithms!"

    In the debut episode of "This Is Only A Test", Dr. Mickey Urdea is marching to his own rhythm - his own algorithm, that is! In order to help you understand how modern diagnostic technologies utilize mathematical algorithms, Mickey is covering the ABCs on AUC, scouring the rock bottom of ROC curves, and connecting the algebraic work of 7th century Persian polymath Muhammad ibn Musa al-Khwarizmi to today's best practices for diagnostic testing. You don't have to rhumba to move to the rhythm of algorithms!

    27 мин.

  6. 26.02.2025

    Ep. 28: “How To Proceed With Proteomics!”

    In this episode of Interesting Stories in the History of Diagnostics, Mickey Urdea is presenting this practical guide on the breadth and depth of the proteome! From an overview of the proteome itself to the techniques used to find subsets of proteins of interest that may correspond to a particular disease state, as well as the top technologies available and what separates them from the rest, this episode will serve as your guide for “How To Proceed With Proteomics!”

    48 мин.

  7. 26.02.2025

    Ep. 27: "Oh Give Me A Home In The Microbiome!"

    Just in time for Thanksgiving, Halteres Associates is serving up a new episode of Interesting Stories In The History of Diagnostics about the microbiome! As you munch on every bite of stuffing, remember that your body is made up of a community of commensal, symbiotic, and pathogenic microorganisms such as bacteria, archaea, fungi, algae, and viruses, as well as protozoans and other protists, so you are actually giving a little taste of Thanksgiving dinner to every microbe who’s along for the ride. And as you recline on your sofa for a post-turkey nap, envision just how that tryptophan is being broken down by your whole microorganism pit crew.

    19 мин.

  8. 26.02.2025

    Ep. 26: "Making Space For Spatial Biology!"

    Spatial biology is a new frontier in molecular biology, but so far as we can tell it has not as of yet been explained all that well, so Mickey Urdea is stepping in to answer some questions about this complex study of tissues within their own 2D- and 3D-contexts, and the technologies being utilized to provide insight toward new strategies to prevent and treat disease, in “Making Space For Spatial Biology!”

    20 мин.
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A video series covering the interesting stories in the history of diagnostics, disease, health technology, medtech charlatans, and more. Hosted by Mickey Urdea, presented by Halteres Associates. You can also watch this podcast on YouTube: https://www.youtube.com/playlist?list=PLz6idmkQtRiaGzpnOJZqpuksfpE0f_SrQ

Информация

  • Автор
    Halteres Associates
  • Годы выхода
    2025 - 2026
  • Выпуски
    38
  • Ограничения
    Без ненормативной лексики
  • Авторские права
    © Halteres Associates
  • Сайт подкаста
    This Is Only A Test