This One Time On Psychedelics

Ryan Sprague
This One Time On Psychedelics

Welcome, fellow explorers of the infinite. If you’re here, it means you’re ready to step beyond the ordinary and into the great unfolding mystery of existence itself. Because psychedelics? They’re not just substances—they’re a doorway to a new way of seeing reality, a lens that reveals the hidden layers of reality we walk through every day. And that’s exactly what we explore here. I’m Ryan Sprague, and This One Time On Psychedelics isn’t just about trippy stories and wild journeys (though trust me, we have plenty of those). It’s about the conversations that hold the power to awaken us, to shift our consciousness, and to remind us that there is far more to this reality than meets the eye.  These are the conversations that expand hearts, challenge perspectives, and guide us back to the wisdom that has always been within us. Whether through plant medicines, altered states, or the everyday magic woven into life itself, this is a space where we step beyond the known and into the infinite. The psychedelic renaissance is here. The future is unwritten. And you, my friend, are a part of it. So buy the ticket. Take the ride. And let’s see how deep this trip goes.

  1. APR 25

    Ep. 213: It’s Not Goodbye, It’s See Ya Later! (feat. Rachel Varitimos)

    Alrighty guys, this episode is extra special to my heart because it’s officially my last episode (for now) on this show before I transition back to the Highly Optimized podcast, my first project that was birthed in 2019 when I chose to start paving my own path, leave my job & go into the unknown. To say the last 3 years of doing this show has been magical, exciting & heart warming would be an understatement & I truly hope all of you continue to tune in on the Highly Optimized podcast because, to be honest, the Highly Optimized podcast just feels much more like me right now. While I love psychedelics, they are simply not the full picture of my life, what I want to share with the world & what I truly feel allows someone to reach the state of being highly optimized & as such, I must follow my fun & I thought who better to join me in this epic send off than my beautiful partner Rachel, who was also my send off guest on the Highly Optimized podcast when I put that show on ice back in 2022. So, with all of that being said, please help me in welcoming todays guest, Rachel Varitimos, to the show to share more about how this decision came to be, why I’m choosing to do it right now & what you can all expect in the future. Sending you all so much love & without further adu, let’s get this show a rolling!  For those wanting to contact Rachel for a reading, go to the link below: https://calendly.com/ravaritimos/75-minute-birth-chart-reading Register for the ONE DOLLAR “Breathe With Cannabis” event happening May 3rd by clicking the link below: https://christopheraugust.mykajabi.com/offers/vmYDwbpf/checkout Subscribe & get ready for the RELAUNCH of the Highly Optimized podcast here: Spotify: https://open.spotify.com/show/0nv2VBYWjCuj4iz3dIwXzI?si=2c6c30f6c9624d21 Apple  https://podcasts.apple.com/us/podcast/highly-optimized/id1498263212 https://www.highlyoptimized.com @therealryansprague

    53 min
  2. APR 11

    Ep. 211: Adventures In Decentralization & Why This Movement Excites Me SO Much (feat. Amethyst Flame)

    For anyone with eyes to see, it’s no secret the world is changing at a rapid rate these days. From political hysteria, to new technology emerging almost daily, it’s safe to say that it’s easier than ever to feel overwhelmed while simultaneously doing your best to keep up. In my opinion, one of the most important & powerful aspects of the new world that we can take the initiative to dive into is the aspect of decentralization. From medicine, to currency, community & more, it’s clear to me that if we want to get back to a world where health is truly about healing, rather than sick-care & money is truly about freedom, rather than dependence & imprisonment, than we must start looking at ways to become more & more decentralized from the centralized powers that have wreaked havoc over the lives of many in the world today. Today’s guest on the show is a returning guest & a brother who is at the cutting edge of the decentralization movement. Over the last 2 years, he has taught me a lot about how to navigate within this space & in this episode, we allowed the divine to take the wheel & went on an epic conversational dialogue on what these 2 years have looked like for each of us, what he sees the future looking like, what you can do to get involved & much, much more.  Guest Links: Digital Stewardship - Instagram - Music This Podcast was produced by Mazel Tov Media. https://www.highlyoptimized.com @therealryansprague

    1h 3m
  3. APR 4

    Ep 210: How The 2018 Farm Bill *Accidentally* Legalized Cannabis (feat. Rand Gifford)

    Every episode I do I am excited about, however, this one holds a special place in my heart for a few reasons. First, anytime I get to speak with someone who is as passionate as I am around regenerative agriculture, I geek out like a small school child. This being said, when I get to speak to someone who not only shares that passion, but is creating revolutionary products alongside it that ANYONE in the U.S. can order to have access to clean, organic hemp products, I get even more excited & that is exactly what todays guest & I will be getting into. From his intro into Cannabis & other psychedelics, to his business, Akira Botanicals, which is a hemp company specializing in organic, high-vibe THCA, CBD & CBG products, to name but a few & one of his most powerful psychedelic stories, this episode is jam packed with everything you’ll need to walk away with a clear understanding of what the 2018 farm bill, that federally legalized hemp here in the U.S., allows you to do now that you may have not been aware of. Sign up for the FREE “How To Cultivate Ceremonial Grade Cannabis” workshop on April 9th at 6pm ET below👇 https://www.highlyoptimized.me/grow-with-cannabis-workshop Purchase Rand’s products below & use code “HIGHLY” at checkout to receive a 15% discount on all of his products👇 Akirabotanicals.com  This Podcast was produced by Mazel Tov Media. https://www.highlyoptimized.com @therealryansprague

    1h 12m
  4. MAR 21

    Ep. 208: Psychedelic Experiences, Presence & What Really Matters In Life (feat. Seibo Shen)

    One of the main reasons I love podcasting so much is, yep, you guessed it, I adore speaking, however, speaking to myself alone in a room is a little weird & definitely not the same experience as when I get to speak to others who stimulate my curiosity, peak my inspiration & remind me of how epic & infinite life can be. As such, this show has become a zone of excitement & growth for me of sorts, consistently allowing me to open myself up to the unknown, to others subjective viewpoints of the world & to find more meaning in the game of life we are all playing a part in & todays episode is spot on to what I just described. Todays guest & I met some years back & immediately connected over the fact that we both not only spent time in the Cannabis industry, but were both passionate around the truth of Cannabis being a psychedelic medicine, among other things such as our love & affinity for psychedelics, spirituality & entrepreneurship, to name but a few. As such, we talked the last few years about doing a show & the divine timing finally aligned for this week on the show! From a deep dive into his journey, to sharing philosophical thoughts & more, this episode is a window into our personal relationship &, In my opinion, a perfect reminder of why connecting with aligned human beings is so important for each of us during our lives. So, please help me in welcoming my man Seibo Shen to the show! Guest Links: Website - Instagram - YouTube - TikTok This Podcast was produced by Mazel Tov Media. https://www.highlyoptimized.com @therealryansprague

    1 hr
  5. MAR 7

    Ep. 206: Opening Up To A Brand New World Through Psychedelic Medicines (feat. Kyle Langan)

    One of, if not my favorite types of stories I enjoy hearing from the psychedelic space are the stories that come from individuals who, at one point, did not resonate with psychedelic medicines at all. You guys have heard me say before & I’ll say it again that for me, I never judge anyone who is opposed or not interested in psychedelic medicines because the truth is nothing is for everybody, however, when someone finds their own way into these medicines & has powerful results thereafter, I jump at the opportunity to have them share their story with me, let alone when it’s someone who is a dear friend & such a kind & big hearted individual like todays guest. He & I first met about 5 years ago through the Enlifted community & right of the bat after meeting him, I knew he was a dedicated, committed & open hearted individual. Since we met, he found his way into psychedelic medicines & let’s just say the effects have been profound, to say the least. As such, in this episode, we dive into his childhood, his adolescence, how pain in his life has led him to breakthroughs time & time again & some words of wisdom from him with regards to how to approach friends, family members & more who we want to share these medicines with, but feel as though they don’t currently resonate with them. This episode is jam packed full of beautiful stories, information & more so sit back, relax & be inspired as we journey down the rabbit hole once more! Guest Links: Substack - Instagram This Podcast was produced by Mazel Tov Media. https://www.highlyoptimized.com @therealryansprague

    1h 7m
4.9
out of 5
36 Ratings

About

Welcome, fellow explorers of the infinite. If you’re here, it means you’re ready to step beyond the ordinary and into the great unfolding mystery of existence itself. Because psychedelics? They’re not just substances—they’re a doorway to a new way of seeing reality, a lens that reveals the hidden layers of reality we walk through every day. And that’s exactly what we explore here. I’m Ryan Sprague, and This One Time On Psychedelics isn’t just about trippy stories and wild journeys (though trust me, we have plenty of those). It’s about the conversations that hold the power to awaken us, to shift our consciousness, and to remind us that there is far more to this reality than meets the eye.  These are the conversations that expand hearts, challenge perspectives, and guide us back to the wisdom that has always been within us. Whether through plant medicines, altered states, or the everyday magic woven into life itself, this is a space where we step beyond the known and into the infinite. The psychedelic renaissance is here. The future is unwritten. And you, my friend, are a part of it. So buy the ticket. Take the ride. And let’s see how deep this trip goes.

You Might Also Like

To listen to explicit episodes, sign in.

Stay up to date with this show

Sign in or sign up to follow shows, save episodes, and get the latest updates.

Select a country or region

Africa, Middle East, and India

Asia Pacific

Europe

Latin America and the Caribbean

The United States and Canada