Totally Transplant

Manpreet Samra

A podcast addressing all things Solid organ transplant. Dr. Samra, a transplant nephrologist, discusses all things and answers questions sent in by listeners. 

Episodes

  1. 19H AGO

    Living Donation with Dr. Gabriel Danovitch

    Send us Fan Mail Dr. Samra sits down with Dr. Danovitch. They talk about the importance of slowing the progression of chronic kidney disease by using medications such as SGLT2 i and GLP-1 RA.   They identify and recognize how hard it is to wait and the uncertainty of getting a transplant  How dialysis is getting better even though it only provides you about 15-20% of your kidney function and allows patients to feel better.  There are certain things that can preclude one from getting a transplant. Such as active cancer, infections.  There are two types of transplants. Deceased donor and living donor. A living donor transplant can have huge advantages such as not ever starting dialysis, and getting a transplant sooner.  It may be beneficial to be listed at multiple transplant centers.  The number of years on dialysis is important.  Living donation is the preferred avenue for kidney transplantation.  1)low wait time 2)kidneys tend to function better and longer 3)you get the transplant on a fixed day and can better prepare for it Traditionally, living donation came from close family member, parents, siblings etc.  Can have friends, neighbors, from your religious place of gathering.  The health of the donor is very important.  They undergo a very intense evaluation process to ensure that it is safe for them to be a donor.  Its a beautiful gift to donate a kidney. Dr. Danovitch shares a endearing story of a donor.  These days you don't you have to be a perfect match. There are ways for us to get around incompatibilites. Organ exchanges or organ chains are one such way. 1/3 of living donors done are done through such exchanges. Have an open mind towards those who want to donate a kidney to you.  They ended the conversation with discussing kidney exchanges as a way to get around incompatibilites. https://www.ovid.com/jnls/transplantjournal/fulltext/10.1097/tp.0000000000004892~gabriel-m-danovitch-md-frcp-hon https://www.livingdonortoolkit.com/ Please note this is not medical advice. It is meant for entertainment purposes only.

    27 min
  2. 09/05/2025

    Improving access to Transplantation and Adolescent to Adult Transition Clinics with Dr. Basu

    Send us Fan Mail Enjoy this converation between Dr. Basu and Dr. Samra. They discuss what ignited their interest in Transplant Nephrology and their path since. How much they enjoy practicing Transplant Nephrology and making a meaningful difference in patients lives. They then discuss Dr. Basu's focus on the vulnerable population. Pregnant women and the use of Belatacept 'bela'. The older adult population and access to transplant, avoiding arbitrary age cut-offs. The importance of utilizing race modification/race neutral formula. All these efforts have been to improve access to transplant for those populations that have historically been at a disadvantage. They then discuss an Adolescent to Adult Transition clinic that was started in concert with pediatric Transplant nephrologist, Dr. Roshan George. At age 18, transplanted patients start to visit the adult Kidney Transplant Clinic so as to start to feel comfortable and safe in this new space while remaiing under the Childrens Transplant Clinic umbrella. They continue this from age 18 to 21 such that by the age of 21 they are now familiar with the adult Transplant Clinic and have built a rapport with the adult Transplant Nephrology Team. Dr. Basu intentionally formed a multi-disciplinary team formed of social workers, physicians, transgender specialists. They identified unique challenges in this population and while addressing those, created a holistic, collaborative and personalized clinic. Improving compliance by utilizing telehealth in follow up visits being one such example. They then discuss Belatacept, a long term immunosuppressant that is un ique in that it is administered intravenously at 4-6 week intervals. At Emory, this is used as a primary immunosuppressant unless there is a contraindication. It has been shown to have better allograft and patient survival, cardiac outcomes and less post transplant diabetes mellitus when compared with calcineurin inhbitors as shown inthe BENEFIT trial. Belatacept cannot be used in those patients who are EBV(epstein barr virus ) positive. They then discuss the gap that older patients have to access to transplant. Some transplant centers have an arbitrary age cut off which we discussed doesnt pertain to all individuals. Further, we discussed the need for guidelines for older adult post transplant management including but not limited to frailty and cognition. We are all in the center of the continous innovation happening in the world of transplant medicine. The future of transplantation is exciting, inlcuding the recent gene edited Xenotransplantation. Increasing the number of transplants performed and aiming for one transplatn for life will be what we strive for as a community.  Dr. Arpita Basu is a Transplant Nephrologist at Emory University. Please note this is not medical advice. It is meant for entertainment purposes only.

    31 min

Ratings & Reviews

5
out of 5
6 Ratings

About

A podcast addressing all things Solid organ transplant. Dr. Samra, a transplant nephrologist, discusses all things and answers questions sent in by listeners.