ToxChats©

ACT ToxChats

The American College of Toxicology podcast program, ToxChats ©, reports on cutting-edge news in toxicological research from around the globe.

  1. 11/07/2025

    Human and Environmental Health Topic: Next Generation Risk Assessment

    In this episode, Aimee Altemus and Adelaide Frimpong speak with Dr. Gary Miller of Columbia University, a widely recognized leader in exposome research. Dr. Miller discusses how the exposome—the full spectrum of environmental exposures throughout a lifetime—is transforming our approach to human and environmental health. He highlights how exposomics, data science, and toxicology contribute to Next Generation Risk Assessment strategies to more accurately predict disease risk and guide public health strategies. From innovative technologies to ethical implications, this conversation offers a compelling look at the future of health science in a complex and rapidly changing world.

    34 min

  2. 10/15/2025

    The Science of Mentorship: A Conversation with Richard DiMarchi

    In this compelling ToxChats podcast episode, hosts Kristin DeSouza and Michael Dorato speak with renowned drug development scientist Richard DiMarchi as he shares his deep understanding into the art and science of mentorship within the biomedical research community. Drawing from decades of experience, Dr. DiMarchi explores the evolving nature of mentorship and its critical role in shaping the next generation of innovators.    Richard DiMarchi shares powerful insights on setting clear expectations in mentor-mentee relationships, delivering constructive criticism with both empathy and precision, and speaking truth to power with integrity and professionalism. The conversation explores how mentorship is a two-way street—where learning flows in both directions and adapting mentorship styles to meet the diverse needs of mentees, as well as building confidence and resilience in emerging scientists, preparing them to lead with both competence and compassion.

    46 min

  3. 09/30/2025

    From RIF to Reboot: A Guide for Early to Mid-Career Toxicologists

    Laid off—or worried you might be—and wondering what's next? In this episode, hosts Sunjay Sethi and Sarah Benjamin partner with the Early Career Professionals to demystify the post-layoff job search for early- to mid-career toxicologists. Kristin DeSouza and Terry Leyden are interviewed to talk about the hard stuff: quiet firing, the market that favors 10+ years’ experience or entry-level candidates, and then get practical about moving forward.

    1h 7m

  4. 07/17/2025

    Discussing the FDA's Announcement to Phase Out Animal Testing in Monoclonal Antibody Development

    This podcast episode is designed to offer listeners a discussion about the FDA’s evolving stance on animal testing and exploring thoughts on its potential phase-out for monoclonal antibody (mAb) therapies. Hosted by Zac Lloyd and featuring expert insights from Dr. Whitney Helms, Executive Director of Nonclinical Development, Large Molecule Discovery at Eli Lilly and Company, and Dr. Diann Blanset, consultant at Akkeri, Inc., this roundtable-style discussion unpacks the scientific, ethical, and regulatory implications of this paradigm shift. Whether you're deep in the biologics pipeline or navigating the changing CRO landscape, this episode offers valuable perspectives on what the future may hold—and how to prepare for it.

    30 min

  5. 07/07/2025

    Specialty Tox Topic: In Vivo Dermal Drug Development

    In this episode, host Zac Lloyd engages with expert in the field Colleen Johnson to discuss critical considerations in designing in vivo nonclinical programs for dermal and topical products. Through this conversation we aim to enhance understanding of key aspects in this specialized area of toxicology.  This podcast is designed to offer listeners an introduction to dermal product drug development.

    35 min

  6. 06/23/2025

    Specialty Tox Topic: In Vitro Dermal Drug Development

    In this episode, we speak with Jean-Philippe Therrien, a senior director of R&D, to discuss critical considerations in designing nonclinical programs for dermal and topical products. Through this conversation, we aim to enhance understanding of key aspects in this specialized area of toxicology. This podcast offers listeners an introduction to dermal product drug development.

    28 min

  7. 05/05/2025

    Occupational Toxicology and Product Quality: Navigating Impurities and Occupational Safety

    In this episode, Dr. Katie Sokolowski and Dr. Tanya McDonnell sit down with Dr. Jessica Graham, a leader in the fields of occupational toxicology and product quality. During our time together, we discuss the current science of safety assessment, focusing on worker safety (occupational toxicology) and patient safety as it relates to pharmaceutical product quality. Dr. Graham explains key concepts in occupational toxicology as well as emerging tools and challenges. She also explores current strategies in managing impurities in therapeutics as well as the evolving regulatory requirements for pharmaceutical drug products. Dr. Graham conveys leading trends in alternative methods for hazard identification and risk assessment, shedding light on how these innovations are transforming human health hazard assessments in the areas of worker safety and impurity assessment. Whether you're a safety professional or just curious about the field, this episode offers essential insights into protecting workers, patients, and maintaining high industry standards.

    44 min

  8. 04/01/2025

    The Past, Present, and Future of Safety Pharmacology

    In this podcast, Dr. Derek Leishman discusses the development of regulatory guidance (ICH and GLP) for safety pharmacology studies. He follows this discussion with a conversation about nonclinical data predicting clinical outcomes, as well as potential changes to future regulatory updates to ICH guidance.

    22 min
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Ratings & Reviews

5
out of 5
8 Ratings

About

The American College of Toxicology podcast program, ToxChats ©, reports on cutting-edge news in toxicological research from around the globe.

Information

  • Creator
    ACT ToxChats
  • Years Active
    2018 - 2025
  • Episodes
    49
  • Rating
    Clean
  • Copyright
    © Copyright ACT ToxChats
  • Show Website
    ToxChats©