TPE Blueprint

MDLifespan

Unlock the secrets of vitality, clarity, and peak performance with "The TPE Blueprint," the first podcast dedicated to the groundbreaking science of Therapeutic Plasma Exchange (TPE). Hosted by Joe Fier and powered by MDLifespan, this podcast delves into the transformative world of TPE, a revolutionary method that detoxifies your blood by removing harmful toxins and inflammatory proteins. Join us for insightful discussions with experts, inspiring patient success stories, and practical strategies designed to empower you with actionable knowledge. Each short, impactful episode is perfect for both wellness enthusiasts and medical professionals. Learn how TPE can restore cognitive function, enhance heart health, boost athletic performance, and support autoimmune conditions. Discover the anti-aging benefits that make TPE a true game changer for vitality.

  1. 3D AGO

    Your Clean Beauty Guide To Avoiding Parabens, Fragrance Loopholes, and Forever Chemicals

    In this episode, Joe Fier dives into the truth behind everyday personal care products and the surprising “invisible drain” they introduce to your vitality. Learn why your skin acts as a sponge for chemicals lurking in lotions, shampoos, and makeup—and get actionable tips to build a safer, cleaner routine without needing a degree in toxicology. Discover practical tools and recommended brands for minimizing toxic exposure, plus how to assess your current products and tackle accumulated chemical loads. If you’re curious about clean beauty and defending your health from hidden threats, this episode is your blueprint. Topics Discussed The hidden chemical load in common skin and hair care routinesHow your skin absorbs toxins—debunking the “barrier myth”Understanding “greenwashing” and why you need data-driven defenses when shoppingUsing the EWG Skin Deep Database and apps like Healthy Living, Yucca, and Think Dirty for product safetyThe dangers of the “fragrance loophole” and how to identify undisclosed ingredientsWhy leave-on products are the most important for clean beautyMD Lifespan’s recommended brands and their commitment to ingredient transparencyThree actionable tips for cleaner routines: going fragrance-free, the post-shave rule, and ditching waterproof makeupThe importance of testing for toxin buildup and ways to flush out accumulated load, including the Plasma Exchange protocol Resources Mentioned MD Lifespan Clean Beauty Guide: http://mdlifespan.com/cleanbeautyEWG Skin Deep Database: https://www.ewg.org/skindeep/EWG Healthy Living App https://www.ewg.org/apps/ Connect with Us MDLifespan Website: https://mdlifespan.com/Subscribe and Listen: https://mdlifespan.com/the-tpe-blueprint-podcasts/Guidebooks: https://mdlifespan.com/guidebooks/Follow on Instagram: https://instagram.com/mdlifespanspan class="ql-ui"...

    6 min
  2. FEB 3

    A Parent’s Guide to Lowering Your Baby’s Toxic Burden

    In this insightful episode of the TPE Blueprint Podcast, host Joe Fier dives deep into one of the most overlooked areas of parenting: safeguarding your baby’s internal environment from invisible toxins. Drawing from his own experiences and collaborations with MD Lifespan, Joe Fier breaks down the hidden risks in common baby products, shares eye-opening research, and provides practical strategies for reducing toxic exposure in your home. Whether you’re a new parent or looking to upgrade your family’s wellness, this episode delivers actionable advice and trusted resources to help you give your child a healthier start. Topics Discussed The unseen threats in our homes: why invisible toxins pose a major risk to babiesHow babies’ developing detox systems make them more vulnerable to environmental toxinsSurprising data about heavy metals in baby foods—even in organic brandsUsing the Environmental Working Group (EWG) Skin Deep database to vet productsWhy standard baby products (bottles, diapers, mattresses) may prioritize convenience over biology and healthThe benefits of choosing non-reactive materials (like medical grade silicone and stainless steel)Mattress safety: what to look for and why certifications like GOTS matterThree super-practical steps you can implement immediately:The 72-hour air-out rule for new itemsDamp dusting to reduce toxins collected in household dustThe “fragrance free” rule to avoid unnecessary chemical exposureThe critical importance of ongoing prevention for the whole familyHow MD Lifespan’s clinical testing and guidebooks can helpJoe Fier’s family-tested tips and the resources he wishes he had known about sooner Resources Mentioned MD Lifespan Clean Baby Guidebook: http://www.mdlifespan.com/cleanbaby Environmental Working Group (EWG) Skin Deep Database: https://www.ewg.org/skindeep/ EWG Verified List: https://www.ewg.org/ewgverified/ Pura Stainless: https://www.purastainless.com/ Naturepedic: a...

    7 min
  3. JAN 20

    Mold Exposure: Why Your Home Might Be the Root Cause of Chronic Health Issues - Brian Karr

    Get your step-by-step MOLD DETOX GUIDEBOOK: mdlifespan.com/mold Is your body’s mystery symptom not actually coming from your body? That’s the provocative question at the heart of this episode of the TPE Blueprint. Today, Joe Fier sits down with renowned mold expert Brian Karr to break down why your home—no matter how clean or dry—might be quietly undermining your health. Mold isn’t just a concern for flood victims or humid climates. One microscopic leak could be quietly affecting your lungs, gut, skin, and even long-term chronic conditions—whether or not you ever see, smell, or suspect a thing. If you care about optimizing health, longevity, or simply want to stop chasing unexplainable symptoms, this is a game-changing conversation. Topics Discussed Why health symptoms may stem from environmental factors—not just internal onesMold's impact on lungs, gut, and skin—and how exposure happens without you noticingMold misconceptions: Why dryness or cleanliness doesn’t guarantee safetyHow the air you breathe can influence multiple body systemsTrend of increasing home exposure since the shift to remote workSubtle water damage: Small leaks and drips as major mold risksChallenges with conventional mold testing and what usually gets overlookedThe Dust Test: A simple, at-home method to reveal mold in your environmentExposure mapping: Prioritizing fixes in your home based on your health data80/20 approach to remediation—focus on what moves the needle mostEasy and fast tips to cut mold exposure: air filtration, air flushing, and dust cleaningWhy symptoms can differ among family members—even in the same house Resources Mentioned The Dust Test: https://thedusttest.com/ Free Consult with We Inspect: https://yesweinspect.com/call?wi_bnd=WIP&wi_plf=Podcast&wi_mch=Guest&wi_cmp=TPE%20PodcastFree Clean Your Moldy Stuff Guide: www.CleanMyMoldyStuff.comTop Remediation Mistakes: www.RemediationMistakes.com Connect with Us span class="ql-ui"...

    41 min
  4. JAN 14

    Doctor Explains How Toxins Destroy the Gut Lining - Dr. Nikol Hopkins

    In this episode, Joe Fier welcomes integrative medicine expert Dr. Nikol Hopkins for an eye-opening conversation about gut health, toxins, and the power of personalized medicine. Dr. Nikol Hopkins breaks down what “leaky gut” really means, why gut health is more than just what you eat, and how environmental toxins can disrupt your body’s natural balance. Personal stories and simple analogies make this episode a must-listen for anyone seeking practical steps to support their gut, minimize toxic exposure, and understand testing options for optimal health. Topics Discussed The Importance of Gut Health: Why the gut is the body’s gatekeeper, its protective lining, and what happens when it’s compromised.Leaky Gut Explained: What intestinal permeability means, how it’s connected to inflammation, and why it matters for whole-body health.Toxins and Their Impact: Which toxins (mycotoxins, heavy metals, PFAs) are most disruptive to gut health, and how they infiltrate the body through food and environment.Common Culprit Foods: The five most likely foods to trigger issues—dairy, corn, soy, sugar, and wheat—and how elimination programs can provide clarity.Mycotoxins in Food and Coffee: Surprising sources of mold toxins, including grains and coffee, and why even quality roasting doesn’t always protect you.How to Heal and Support the Gut: Practical steps including elimination diets, supplements, and the power of personalized testing.Testing & Interpreting Data: The value of toxin panels and personalized analysis to create an effective avoidance and healing strategy.Everyday Detox Strategies: How to start reducing exposure—like swapping out plastic kitchenware, nonstick pans, and processed foods for safer alternatives.Taking Action in Your Home: Step-by-step advice for making your space healthier, from air and water purification to investigating food packaging choices.The Role of Personalized Medicine and TPE: How Therapeutic Plasma Exchange (TPE) and MD Lifespan’s protocols can be a next step for those at the end of their rope with chronic illness.Advocating for Your Health: Why you have to be your own health advocate in today’s world and take small steps to protect you and your family. Resources Mentioned Super Gut by Dr. William Davis: https://drdavisinfinitehealth.com/product/super-gut/Environmental Working Group (EWG): https://www.ewg.org/Made Safe: a href="https://madesafe.org/" rel="noopener...

    46 min
  5. 12/24/2025

    The 5 Episodes That Changed How We Think About Toxins, Health, and Healing

    What if optimizing your health wasn’t just about diet, exercise, or the latest supplement, but hinged on the very “oil” running through your system? In this recap episode of the TPE Blueprint Podcast, host Joe Fier is back at some of our most impactful episodes of the year. We’ll take a look at conversations with Dr. Paul Savage, Dr. Jill Carnahan, Dr. Paul Anderson, Dr. Janet Eng, and Dr. Muhammad Mansour, to break down therapeutic plasma exchange (TPE), mitochondria’s critical role in health, toxic burden from mold, and actionable strategies for real healing. Whether you’re biohacking or desperate for answers, this episode digs beneath the surface to challenge conventional medicine and empower your physiological reset. Topics Discussed What Is Plasma Exchange? Dr. Paul Savage breaks down the history and modern mechanics of TPE—and why it’s not a fad.The Car Analogy for Your Health: How your body’s plasma exchange is like an oil change for your engine, and why cellular “cleanliness” matters.Mitochondria & Cellular Mechanics: The role of mitochondria in energy production and disease, with Joe Fier and guests highlighting how toxins can slow you down at the cellular level.The Menace of Mold: Dr. Jill Carnahan explains mold’s surprisingly high prevalence, why genetics matter, and how environmental toxins can disrupt everything from your cardiovascular system to your hormones.Building and Environmental Health:Modern building trends and errors that lead to hidden water intrusion—and how your home’s design may affect your well-being.Assessment and Personalized Care: Dr. Janet Eng and Dr. Muhammad Mansour discuss unique approaches to evaluating metabolism, body composition, and toxic burden, emphasizing a multimodal, tailored plan for every patient.Advanced Therapies & Testing: From blood and urine screens to light therapies, what works and why there isn’t a “silver bullet” in recovery.Sympathetic Overdrive & Parasympathetic Healing: How modern stress affects our ability to heal, and practical tactics to shift toward true rest and recovery. Full Episodes to Check Out Dr. Paul Savage: https://mdlifespan.com/tpe-bp-podcast/tpe-blueprint-ep-03-what-is-plasma-exchange-a-deep-dive-with-dr-paul-savage/Dr. Jill Carnahan: https://mdlifespan.com/tpe-bp-podcast/tpe-blueprint-podcast-ep-19-is-mold-behind-your-fatigue-brain-fog-dr-jill-carnahan-unpacks-the-hidden-epidemic-breakthrough-detox-solutions/Dr. Paul Anderson: a...

    22 min
  6. 12/16/2025

    Avoid Toxins: Easy Produce Picks and Cleaning Tricks for Daily Health

    In this episode, Joe Fier explores the ins and outs of reducing exposure to pesticides through smart produce shopping and cleaning. Drawing on the latest research from the Environmental Working Group (EWG), Joe Fier clarifies which fruits and vegetables you should always buy organic (the "Dirty Dozen"), which are safer when conventionally grown (the "Clean 15"), and simple, effective ways to wash your produce at home. The episode also touches on hidden toxins in pantry staples, especially crucial for kids and those focused on detox or hormone support. Listeners get actionable steps to shop smarter, clean better, and support long-term health. Topics DiscussedUnderstanding the "Dirty Dozen" and "Clean 15" produce listsWhy some fruits and veggies have more pesticide residues than others2025 updates: new additions to both listsCost-saving strategies for organic and conventional produceStep-by-step guide to washing produce to reduce pesticide exposureMyth-busting: What washing produce can and cannot eliminateHidden toxins in pantry staples like rice-based baby foodsThe link between everyday toxins and chronic health issuesSimple action plan for shopping, cleaning, and tracking healthHow to assess your toxin burden and personalize your health approach Resources Mentioned Environmental Working Group (EWG) Produce Lists: https://www.ewg.org/foodnews/MDLifespan Blog Post: https://mdlifespan.com/dirty-dozen-clean-fifteen-2025/ Timestamps 00:00 Welcome to the TPE Blueprint 01:01 The 2025 Dirty Dozen 01:36 The 2025 Clean Fifteen 02:06 Smart Cart Strategy 02:22 At Home Cleaning 02:52 Quick Myth Check 03:12 What About Beyond Produce 03:50 Simple Action Plan 04:26 Get a Free Consult 04:56 Closing Connect with Us MDLifespan Website: https://mdlifespan.com/ Subscribe and Listen: https://mdlifespan.com/the-tpe-blueprint-podcasts/  Guidebooks: https://mdlifespan.com/guidebooks/  Follow on Instagram: https://instagram.com/mdlifespanMDLifespan Toxin Testing: https://mdlifespan.com/toxin-test Use code “podcast200” for a discount. Like what you heard? Screenshot the Dirty Dozen and Clean 15 lists to make your next shopping trip easier! Don’t forget to subscribe on your favorite podcast platform and drop us a comment about your own strategies for minimizing toxins. Your journey to cleaner, healthier eating starts here—join us! Disclaimer: MDLifespan PlasmaXchange protocols are designed to support general health and wellness. They are not intended to diagnose, treat, cure, or prevent any disease. The information provided on this podcast is for educational purposes only and should not replace medical advice. Please consult with your healthcare provider before beginning any new health program, especially if you have a medical condition or are taking prescribed medications.

    5 min
  7. 12/10/2025

    Is Your Morning Coffee Making You Sick?

    In this insightful episode of the TPE Blueprint Podcast, Joe Fier takes listeners on a deep dive into the hidden world of mold and mycotoxins in coffee. He explores how these contaminants can sneak into even high-quality beans, what impact they may have on your health, and practical steps you can take to enjoy your daily brew with greater confidence. Whether you’re a passionate coffee drinker or just looking to make healthier choices, you’ll learn why quality matters—and how to choose safer options for yourself and your family. Topics Discussed What are mycotoxins, and how do they end up in coffee beans?The two most common coffee mycotoxins: aflatoxin B1 and ochratoxin A—how they affect your healthHow coffee production methods (wet and dry processing) influence mold riskThe role of storage, shipping, and climate control in mold contaminationHealth impacts of mycotoxins: fatigue, brain fog, inflammation, and chronic conditionsMisconceptions about coffee roasting and mold/mycotoxin destructionHow to choose coffee brands that test for mold and mycotoxinsTips for storing coffee at home to avoid unwanted mold growthThe importance of personal toxin testing and available tools to evaluate exposureResources for further learning and taking proactive steps for better health Resources Mentioned MDLifespan Guidebooks: https://mdlifespan.com/guidebooks MDLifespan Toxin Testing: https://mdlifespan.com/toxin-test Use code “podcast200” for a discount. Connect with Us MDLifespan Website: https://mdlifespan.com/ Subscribe and Listen: https://mdlifespan.com/the-tpe-blueprint-podcasts/  Guidebooks: https://mdlifespan.com/guidebooks/  Follow on Instagram: https://instagram.com/mdlifespan  Love your morning coffee? Take charge of your health by choosing brands committed to testing and transparency. Subscribe to the TPE Blueprint Podcast for more actionable insights—and share this episode with a friend who deserves a safer cup! Disclaimer: MDLifespan PlasmaXchange protocols are designed to support general health and wellness. They are not intended to diagnose, treat, cure, or prevent any disease. The information provided on this podcast is for educational purposes only and should not replace medical advice. Please consult with your healthcare provider before beginning any new health program, especially if you have a medical condition or are taking prescribed medications.

    7 min
  8. 12/02/2025

    Groundbreaking Protocols for Removing Environmental Toxins and Boosting Lifespan

    In this episode, Dr. Savage pulls back the curtain on just how pervasive environmental toxins have become, why traditional functional medicine approaches are struggling, and shares a scientifically validated protocol for “changing the paradigm” in personal health. If you’re tired of hearing the same old advice and ready to reclaim your well-being, this is the talk you need. Topics Discussed The history and evolution of Dr. Paul Savage’s career, from trauma care to pioneering natural hormone clinicsThe alarming rise of toxin exposure in the U.S. and globally, affecting all age groups and contributing to generational health issuesLimitations of conventional detox methods in removing persistent toxins like PFAS and microplasticsThe World Health Organization’s recognition of environmental toxins as the leading global cause of deathThe direct link between toxins, chronic inflammation, and over 200 diseasesIntroduction to therapeutic plasma exchange (TPE) as a highly effective “oil change” for the human bodyMDLifespan’s innovative, patented protocol combining TPE with functional medicine and regenerative therapiesReal-world case studies demonstrating dramatic improvements in toxin levels, immune function, cognitive health, and resilience against chronic diseasePractical strategies for minimizing toxin exposure in daily lifeThe shift in medical philosophy: Why what you remove from your body matters more than what you add Connect with Us MDLifespan Guidebooks: https://mdlifespan.com/guidebooks MDLifespan Toxin Testing: https://mdlifespan.com/toxin-test Use code “podcast200” for a discount.Visit our website: TPE Blueprint Podcast If you found this episode eye-opening, help us spread the word! Subscribe to the TPE Blueprint Podcast for more expert interviews, actionable tips, and the latest breakthroughs in personalized health. Your journey to feeling your best starts here—don’t miss an episode! Disclaimer: MDLifespan PlasmaXchange protocols are designed to support general health and wellness. They are not intended to diagnose, treat, cure, or prevent any disease. The information provided on this podcast is for educational purposes only and should not replace medical advice. Please consult with your healthcare provider before beginning any new health program, especially if you have a medical condition or are taking prescribed medications.

    14 min

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About

Unlock the secrets of vitality, clarity, and peak performance with "The TPE Blueprint," the first podcast dedicated to the groundbreaking science of Therapeutic Plasma Exchange (TPE). Hosted by Joe Fier and powered by MDLifespan, this podcast delves into the transformative world of TPE, a revolutionary method that detoxifies your blood by removing harmful toxins and inflammatory proteins. Join us for insightful discussions with experts, inspiring patient success stories, and practical strategies designed to empower you with actionable knowledge. Each short, impactful episode is perfect for both wellness enthusiasts and medical professionals. Learn how TPE can restore cognitive function, enhance heart health, boost athletic performance, and support autoimmune conditions. Discover the anti-aging benefits that make TPE a true game changer for vitality.