Unqualified Curiosity

qsmith1713

A weekly dive into the news surrounding science.

  1. 12/26/2025

    Episode 28: What Exactly Makes and Expert?

    Welcome back to the (more) regularly scheduled programming! This week, we take a deeper dive than usual into what (at least partially) makes up an expert. What are the differences between the novices and experts on the cognitive scale? How do we best go about developing our skills to become experts in our passions? And how to tap into the coveted benefits of expertise like the flow state, creativity, and high productivity? This one was really fun to look into, and there is certainly a lot more to learn about this topic! With that said, I tried to present the most actionable items I could find in the literature to best enhance your learning and development. Thanks for listening and stay curious!   Following are the citations for this episode: Chunking and Template Theory: Thought and Choice in Chess - Adriaan D. de Groot - Google Books Perception in chess - ScienceDirect Templates in Chess Memory: A Mechanism for Recalling Several Boards - ScienceDirect Expertise in complex decision making: the role of search in chess 70 years after de Groot - PubMed Chunks in expert memory: evidence for the magical number four ... or is it two? - PubMed Classics in the History of Psychology -- Miller (1956) Replication and Analysis of Ebbinghaus’ Forgetting Curve - PMC Automaticity, Flow, and Creativity: Brain Scans of Jazz Musicians Reveal How to Reach a Creative ‘Flow State’ | Scientific American A Review on the Role of the Neuroscience of Flow States in the Modern World - PMC How Brain Efficiency Facilitates Flow State Experiences | Psychology Today Flow State Mastery: Minimizing Cognitive Friction - Liminary Frontiers | A Scoping Review of Flow Research Physiological assessment of the psychological flow state using wearable devices | Scientific Reports EEG-based functional connectivity patterns during boredom in an educational context | Scientific Reports Turning on Flow Means Turning Off Parts of the Brain (PDF) Neural Mechanisms and Benefits of Flow: A Meta Analysis

    1h 20m
  2. 04/14/2025

    Episode 24: Metabolic Impacts of Sleep and Transparent Cardboard

    The double dozen has been reached! Tune in next week for the quarter century. This week, we learn about the importance of sleep for high-level cognitive function and memory development. After that, a look into the jack-of-all-trades cardboard product that is transparent and biodegradable and can hold boiling water, quite the resume for some cardboard. As always (got it right this time, Nathan,) thanks for listening, and stay curious!   Citations Follow: Sleep Loss as a Metabolic Disorder: Sleep loss is a metabolic disorder | Science Signaling Metabolic Disorders: Symptoms & Causes | NewYork-Presbyterian The Role of Astrocytes in the Central Nervous System Focused on BK Channel and Heme Oxygenase Metabolites: A Review - PMC Astrocytes: The Unsung Heroes of Learning and Memory - Neuroscience News Connecting insufficient sleep and insomnia with metabolic dysfunction - PMC [2301.09565] Estimating the energy requirements for long term memory formation Estimating the energy requirements for long term memory formation Is plasticity of synapses the mechanism of long-term memory storage? | npj Science of Learning UI neuroscientists identify mechanism for long term memory storage | Carver College of Medicine Glucose enhancement of human memory: A comprehensive research review of the glucose memory facilitation effect - ScienceDirect Upregulated energy metabolism in the Drosophila mushroom body is the trigger for long-term memory | Nature Communications Astrocyte-neuron lactate transport is required for long-term memory formation - PMC Metabolism - Wikipedia Transparent Cardboard Fully circular shapable transparent paperboard with closed-loop recyclability and marine biodegradability across shallow to deep sea Eco-Friendly Polymers: The 2025 Shift to Biodegradable Plastics The Advances of Plastic Sustainability: 5 Trends to Watch in 2025 How Long Does It Take for Plastic to Decompose? | Chariot Energy How long for biodegradable plastic to decompose? - BioBottles™ Plastic Pollution Affects Sea Life Throughout the Ocean | The Pew Charitable Trusts Plastic pollution in the marine environment - PMC Fully circular shapable transparent paperboard with closed-loop recyclability and marine biodegradability across shallow to deep sea - PMC Discover Paperboard: Types, Uses, And Manufacturing Process Hazy Transparent Cellulose Nanopaper | Scientific Reports Biobased Biodegradable Plastics Market Outlook, 2025 to 2035 100+ Plastic in the Ocean Statistics & Facts 2025 How does plastic pollution affect marine life? | Fauna & Flora

    36 min
  3. 04/07/2025

    Episode 23: Brain Computer Interface Improvements and Making Humans Mosquito Repellant

    Happy Monday, everyone. This week, we learn about the improvements in the speech-related applications of brain-computer interfaces. An impressive decrease of over 100% for the response time needed has made these devices much more practically useful. After that, we learn how a completely unrelated drug for a rare metabolic disease can be used to make human blood poisonous to mosquitos. As always, thanks for listening, and stay curious!   Citations Follow: Brain Computer Interfaces: Brain implant translates thoughts to speech in an instant A streaming brain-to-voice neuroprosthesis to restore naturalistic communication | Nature Neuroscience A high-performance neuroprosthesis for speech decoding and avatar control | Nature Brain-reading device is best yet at decoding ‘internal speech’ Brain Waves to Voice: Revolutionary Technology Gives Speech to the Speechless Brain-to-Voice AI Streams Natural Speech for People with Paralysis - Neuroscience News Ai-powered system enables real-time speech generation for paralyzed individuals Harnessing Recent Online Data to Improve Brain-Computer Interface Operation Clinical Applications of Brain-Computer Interfaces: Current State and Future Prospects - PMC The future of brain–computer interfaces in medicine Harnessing Recent Online Data to Improve Brain-Computer Interface Operation Harnessing Recent Online Data to Improve Brain-Computer Interface Operation Brain–computer interface - Wikipedia Frontiers | The Use of Brain–Computer Interfaces in Games Is Not Ready for the General Public Researchers use BCIs to restore speech in people with paralysis Brain-to-Voice AI Streams Natural Speech for People with Paralysis - Neuroscience News Are Alexa And Siri Considered AI? | OpenGrowth | OpenGrowth Internal Mosquito Repellant: Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone | Science Translational Medicine Nitisinone - Wikipedia 4-Hydroxyphenylpyruvate dioxygenase - Wikipedia Tyrosinemia - Wikipedia Drug For Rare Disease Turns Human Blood Into Mosquito Poison : ScienceAlert Fighting the World's Deadliest Animal | Global Health | CDC 10 Mosquito Facts in Honor of World Mosquito Day | RTI Vector-borne Diseases - American Mosquito Control Association Vector-borne Diseases - American Mosquito Control Association Declining malaria, rising of dengue and Zika virus: insights for mosquito vector control - PubMed What Purposes Do Mosquitoes Serve in Ecosystems? | Britannica Drug For Rare Disease Turns Human Blood Into Mosquito Poison : ScienceAlert Malaria parasite life cycle | Malaria Vaccines Nitisinone Side Effects: Common, Severe, Long Term Mosquito Killer: A New Approach to Control Plasmodium falciparum - Wikipedia Vector-borne diseases

    32 min
  4. 03/31/2025

    Episode 22: Using Stem Cells to Treat Paralysis and The Discovery of Novel Antibiotics

    Welcome back to the traditional format today with no more money and politics involved. I know you are sad but that's ok, I'm not. Today, we learn about some progress in the treatment of Grade A spinal cord injuries through induced pluripotent stem cell therapy. After that, it's all about antibiotic-resistant bacteria resistant antibiotics, which is my new favorite pallandrome. Thanks for listening, and stay curious!   Citations follow: Induced Pluripotent Stem Cells to Treat Paralysis: Paralysed man stands again after receiving ‘reprogrammed’ stem cells ‘Reprogrammed’ stem cells to treat spinal-cord injuries for the first time Spine Sustained delivery of neurotrophic factors to treat spinal cord injury Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences - PMC Cell therapy for spinal cord injury using induced pluripotent stem cells - PMC Reprogramming methods and efficiency analysis of iPSCs - BOC Sciences Differentiation and characterization of neural progenitors and neurons from mouse embryonic stem cells - PMC Characterizing Natural Recovery after Traumatic Spinal Cord Injury | Journal of Neurotrauma Stem Cell-Based Approaches for Spinal Cord Injury: The Promise of iPSCs Induced pluripotent stem cells: applications in regenerative medicine, disease modeling, and drug discovery - PMC iPSC Application - Creative Biolabs Cell therapy for spinal cord injury using induced pluripotent stem cells - PMC Differentiation and characterization of neural progenitors and neurons from mouse embryonic stem cells - PMC When Fibroblasts MET iPSCs: Cell Stem Cell Generation of induced pluripotent stem cells - PubMed Japanese scientists use stem cell treatment to restore movement in spinal injury patients Antibiotic-Resistant Bacteria Resistant Antibiotic Discovery: New antibiotic that kills drug-resistant bacteria discovered in technician’s garden Lasso-shaped molecule is a new type of broad-spectrum antibiotic Scientists Discover A Potential Game Changer in Fighting Drug-Resistant Bacteria | Health and Me The natural history of antibiotics - PMC Frontiers | Synergistic action of antimicrobial peptides and antibiotics: current understanding and future directions Towards the sustainable discovery and development of new antibiotics | Nature Reviews Chemistry A Broad Spectrum Lasso Peptide Antibiotic Targeting the Bacterial Ribosome - PubMed New peptide antibiotic stops bacteria by binding where no drug has before

    33 min
  5. 03/24/2025

    Episode 21: Recent Government Action and Its Impact on Scientific Research

    Week two of the politically adjacent Unqualified Curiosity Podcast! I know I know you love hearing about money, politics, and international relations but unfortunately, this is the last week of it );. For now, though we take a shallow dive into the recent government action and its impacts on grant-related research funding, the topics of research, and international collaboration in research. You will come to find that pretty much everything is up in the air right now, but still an important topic to stay up to date on in the scientific realm. As always thanks for listening and stay curious!   Citations follow: Government Action Impacts on Scientific Research: Understanding the NIH's New Indirect Cost Rate Policy: What Nonprofit and Higher Education CFOs Need to Know | BDO Impact of Trump Administration Directives on Scientific Research in the U.S. | Advisories | Arnold & Porter Massive Cuts in Research Funding Hamper Necessary Innovations in Key Technologies for the Energy Transition - Fraunhofer ISE Fiscal Year 2025 Department of Energy Funding: House vs. Senate Markups | Insights | Holland & Knight Trump blocks renewable energy approvals on federal lands and waters - DCD What Businesses Need to Know About DEI in the Trump Era: FAQs for Employers | Fisher Phillips What Businesses Need to Know About DEI in the Trump Era: FAQs for Employers | Fisher Phillips What Businesses Need to Know About DEI in the Trump Era: FAQs for Employers | Fisher Phillips NIH Cuts Indirect Cost Payments: “Lights in Labs Nationwide Will Literally Go Out” - Ophthalmology Advisor Researchers Respond to NIH Funding Cuts and Indirect Costs Cap NSF Budget Cuts Would Put the Future of U.S. Innovation and Security at Risk - CRA How cuts at U.S. aid agency hinder university research Trump admin's NIH cuts threaten student admissions, medical research What’s in store for US science as funding bill averts government shutdown Trump Administration Puts Subsidized Green-Energy Companies on a Diet | The Heritage Foundation US science rues ongoing demotion of research under President Trump – Physics World How Trump's executive orders are disrupting academic research Trump orders cause chaos at science agencies | Science | AAAS NIH funding freeze stalls $1.5 billion in medical research grant funding : Shots - Health News : NPR Trump’s NIH Is Right to Cap Funding for Universities’ Indirect Costs ‘All this is in crisis’: US universities curtail staff, spending as Trump cuts take hold Trump team ‘survey’ sent to overseas researchers prompts foreign interference fears

    34 min

Ratings & Reviews

5
out of 5
3 Ratings

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A weekly dive into the news surrounding science.