Metabolism Made Easy

A J Ghalayini, Ph.D.
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This podcast describes selected biochemistry content that could be useful to premedical/medical students. Similar content (podcasts and videos) is available at: https://medbiochem.org/ or check out my YouTube channel: Metabolism Made Easy These podcasts and videos cover selected topics in medical biochemistry. A J Ghalayini, Ph.D. Bio for Dr. Ghalayini: Dr. Ghalayini received his Ph.D. in Biochemistry from the University of Houston, Houston, Texas. He has over 3 decades of experience in research and medical education as professor of biochemistry at 5 different universities.

  1. 2 NGÀY TRƯỚC

    Fatty acids: Sources & Fates

    Fatty acids are derived from 3 distinct sources: 1. Digestion of dietary triacylglycerol; 2. Biosynthesis in the liver; 3. Lipolysis of stored triacylglycerol in adipose tissue. Fatty acids play several key cellular roles in energy production, energy storage, membrane synthesis, and inflammation.

    3 phút
  2. The Ingenious Journey of Dietary Fat-AI Podcast

    20 THG 9

    The Ingenious Journey of Dietary Fat-AI Podcast

    This podcast describes the breakdown and transport of dietary fats within the body, beginning with pancreatic lipase in the small intestine converting triacylglycerols into absorbable components. These components are then repackaged into chylomicrons within the intestinal mucosa, which are released into the lymph and bloodstream for delivery throughout the body. During circulation, lipoprotein lipase facilitates the release of fatty acids from chylomicrons for tissue uptake. Furthermore, the text explains how, during periods of fasting, hormone-sensitive lipase in adipose tissue is activated by epinephrine, leading to the release of stored fatty acids into the bloodstream to serve as an energy source for several tissues.

    10 phút
  3. Glycogen Metabolism: Liver vs. Muscle-AI Podcast

    12 THG 9

    Glycogen Metabolism: Liver vs. Muscle-AI Podcast

    The provided source distinguishes between glycogenolysis in the liver and muscle, highlighting their differing metabolic outcomes. Liver glycogenolysis is unique because the liver possesses glucose-6-phosphatase, an enzyme that allows it to convert glucose-6-phosphate into free glucose, which can then be released into the bloodstream. Conversely, muscle glycogenolysis only yields glucose-6-phosphate, which is utilized internally for energy production through glycolysis as muscle tissue lacks glucose-6-phosphatase. This difference explains why the liver can contribute to maintaining blood glucose levels, while muscle energy is for its own use. The source emphasizes the liver's distinct role in glucose homeostasis due to this enzymatic presence.

    10 phút
  4. The Breath of Life: Oxygen & Cellular Respiration

    2 THG 9

    The Breath of Life: Oxygen & Cellular Respiration

    The provided text from the "Metabolism Made Easy" YouTube channel explains the critical role of oxygen in the Electron Transport Chain (ETC), a vital process for cellular energy production. It highlights how hypoxia, or a lack of oxygen, significantly inhibits the ETC, thereby reducing the output of ATP, the body's primary energy currency. This reduction in ATP can severely impair the function of aerobic tissues like the brain and heart, which heavily rely on oxygen-dependent pathways for energy. The source emphasizes that multiple mitochondrial catabolic processes that produce NADH and FADH2 will not generate usable energy in the absence of sufficient oxygen, ultimately leading to tissue damage, particularly in the brain, which is highly dependent on glucose oxidation for ATP.

    11 phút

  5. 30 THG 8

    Why We Need Oxygen?

    Around 95% of the oxygen we breathe is consumed by the electron transport chain in the mitochondria. This process is also known as cellular respiration. Its function is to oxidize the high-energy molecules produced from mitochondrial catabolism into ATP, a more usable form of energy.

    3 phút

  6. 25 THG 8

    Electron Transport Chain: Cellular Respiration

    The podcast describes the cellular role of the mitochondrial electron transport chain (ETC) and oxidative phosphorylation. This coupled oxidative process converts high energy molecules (NADH, FADH2) into a usable form of energy (ATP) by transporting their electrons to oxygen through the ETC. Oxygen consumption by the ETC accounts for the major cellular use of oxygen by the cell.

    3 phút

  7. 20 THG 8

    The TCA Cycle & Acetyl CoA: A Metabolic Crossroad

    Acetyl CoA is a molecule derived from various dietary sources that drives energy production by the TCA cycle, producing the equivalent of 12 ATP per turn of the cycle. Acetyl CoA has 5 distinct metabolic sources including pyruvate, amino acids, fatty acids, ketone bodies and alcohol.

    3 phút

  8. 13 THG 8

    Major Energy Sources In The Diet

    The major energy sources in the diet are provided by carbohydrates and fat in the form of triacylglycerol (triglycerides). Catabolism of these components produces different amounts of energy (ATP). A comparison of ATP output from catabolism of glucose , palmitate, and acetoacetate is also covered.

    3 phút
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Giới Thiệu

This podcast describes selected biochemistry content that could be useful to premedical/medical students. Similar content (podcasts and videos) is available at: https://medbiochem.org/ or check out my YouTube channel: Metabolism Made Easy These podcasts and videos cover selected topics in medical biochemistry. A J Ghalayini, Ph.D. Bio for Dr. Ghalayini: Dr. Ghalayini received his Ph.D. in Biochemistry from the University of Houston, Houston, Texas. He has over 3 decades of experience in research and medical education as professor of biochemistry at 5 different universities.

Thông Tin

  • Nhà sáng tạo
    A J Ghalayini, Ph.D.
  • Năm hoạt động
    2021 - 2025
  • Tập
    193
  • Xếp hạng
    Sạch
  • Bản quyền
    © A J Ghalayini, Ph.D.
  • Trang web chương trình
    Metabolism Made Easy

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