Your Fertility Pharmacist

Your Fertility Pharmacist—Infertility and Reproductive Medicine, Fertility Medications
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Your Fertility Pharmacist

The latest fertility research presented by a board-certified clinical pharmacist. For women trying to conceive, this information can help to navigate the science behind the fertility journey.

  1. OCT 27

    Fight of the Follitropins: Gonal-F vs. Puregon

    This study compared efficacy of two r-FSH medications: follitropin alpha (Gonal-F) vs. follitropin beta (Puregon) on the number of live births cumulatively (CLBR). This was looking at patients 21-45yrs doing fresh embryo transfer after their first IVF or ICSI cycle. Resources Cao JX, Song JY. Follitropin Alpha versus Follitropin Beta in IVF/ICSI Cycle: A Retrospective Cohort Study. Drug Des Devel Ther. 2024;18:4359-4369. Published 2024 Sep 26. doi:10.2147/DDDT.S479700 Van den Haute L, Drakopoulos P, Verheyen G, De Vos M, Tournaye H, Blockeel C. Follitropin alpha versus beta in a first GnRH antagonist ICSI cycle: a retrospective cohort study. Reprod Biomed Online. 2021;43(4):655-662. doi:10.1016/j.rbmo.2021.06.014

    3 min

  2. SEP 8

    PRP and POR

    The most rigorously designed trial (to date) of intraovarian PRP demonstrated no improvements in # of mature oocytes obtained or # of live births versus no injections.

    11 min

  3. APR 24

    Letrozole vs. Clomiphene: the OG Study

    Resources Bronson R. and Kruljac I, Butorac D, Vrkljan M. and Legro RS, Zhang H; Eunice Kennedy Shriver NICHD Reproductive Medicine Network. Letrozole or clomiphene for infertility in the polycystic ovary syndrome. N Engl J Med. 2014;371(15):1463-1464. doi:10.1056/NEJMc1409550 Centers for Disease Control and Prevention. PCOS (Polycystic Ovary Syndrome) and Diabetes. https://www.cdc.gov/diabetes/basics/pcos.html. Accessed April 21, 2024. Franik S, Kremer JA, Nelen WL, Farquhar C. Aromatase inhibitors for subfertile women with polycystic ovary syndrome. Cochrane Database Syst Rev. 2014;(2):CD010287. Published 2014 Feb 24. doi:10.1002/14651858.CD010287.pub2 Franik S, Le QK, Kremer JA, Kiesel L, Farquhar C. Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome. Cochrane Database Syst Rev. 2022;9(9):CD010287. Published 2022 Sep 27. doi:10.1002/14651858.CD010287.pub4 Legro RS, Brzyski RG, Diamond MP, et al. Letrozole versus clomiphene for infertility in the polycystic ovary syndrome [published correction appears in N Engl J Med. 2014 Oct 9;317(15):1465]. N Engl J Med. 2014;371(2):119-129. doi:10.1056/NEJMoa1313517 Legro RS, Diamond MP, Coutifaris C, et al. Pregnancy registry: three-year follow-up of children conceived from letrozole, clomiphene, or gonadotropins. Fertil Steril. 2020;113(5):1005-1013. doi:10.1016/j.fertnstert.2019.12.023 Palomba S, Santagni S, Falbo A, La Sala GB. Complications and challenges associated with polycystic ovary syndrome: current perspectives. Int J Womens Health. 2015;7:745-763https://doi.org/10.2147/IJWH.S70314 World Health Organization. Polycystic Ovary Syndrome. World Health Organization; 2023. Accessed April 21, 2024. https://www.who.int/news-room/fact-sheets/detail/polycystic-ovary-syndrome Zhang H. Pregnancy in Polycystic Ovary Syndrome II (PPCOSII). ClinicalTrials.gov identifier: NCT00719186 . Updated June 14, 2018. Accessed April 20, 2020. https://classic.clinicaltrials.gov/ct2/show/NCT00719186

    11 min

  4. FEB 10

    Infection with COVID-19 After Embryo Transfer

    A new study examines the associations between COVID-19 infection with pregnancy and miscarriage rates, looking at the first ten weeks after fresh embryo transfer.

    9 min

  5. 09/30/2023

    Liraglutide and Male Reproductive Health

    A study compared fertility and sexual markers in obese men with low testosterone and erectile dysfunction who took liraglutide, uFSH + HCG, or testosterone. These men separated into three groups based on their plans for parenthood; results showed impressive improvements on the GLP-1 agonist liraglutide.

    10 min

  6. 07/12/2023

    Use of a New Oral Drug in Egg Donor Cycles

    A recent study compared GnRH antagonists in egg donor ovarian stimulation cycles. The first drug is a newer agent, elagolix (Orilissa), that is taken as a tablet at night. The older drug is an injectable agent called ganirelix (Fyremadel). How did elagolix stack up with eggs retrieved and embryos formed vs. ganirelix? Were there adverse events, like ovarian hyperstimulation or early LH surge? Results and what they mean for upcoming egg donor cycles are explored in this episode.

    11 min

  7. 06/20/2023

    Improving Ovarian Function in Obesity with IV FSH

    A new trial tested a new way to give FSH to improve ovarian function in obese women without PCOS who are struggling to conceive.

    11 min

  8. 05/23/2023

    Dex + Letrozole for PCOS Ovulation Induction

    This study adds low-dose dexamethasone to letrozole in women with PCOS who failed to ovulate with letrozole alone. This study looked at ovulation, pregnancy, and live birth rates and took place at the Mayo Clinic from 2019 to 2022.

    10 min
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About

The latest fertility research presented by a board-certified clinical pharmacist. For women trying to conceive, this information can help to navigate the science behind the fertility journey.

Information

  • Creator
    Your Fertility Pharmacist—Infertility and Reproductive Medicine, Fertility Medications
  • Years Active
    2020 - 2024
  • Episodes
    54
  • Rating
    Clean
  • Show Website
    Your Fertility Pharmacist

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