Sami Inkinen (@samiinkinen) is a Finnish-born, Stanford-trained entrepreneur and the founder and CEO/president of Trulia and Virta Health. Virta is on a mission to reverse metabolic disease in one billion people using technology, AI, and nutrition. A world-class endurance athlete, Sami is a triathlon age-group world champion and an 8-hour, 24-minute Ironman finisher, having completed the Hawaii Ironman World Championship seven times. This episode is brought to you by: Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/TimAG1 all-in-one nutritional supplement: DrinkAG1.com/TimWealthfront high-yield cash account: Wealthfront.com/Tim Wealthfront disclaimer: New clients get 3.30% base APY from program banks + additional 0.75% boost for 3 months on your uninvested cash (max $150k balance). Terms and conditions apply. The Cash Account offered by Wealthfront Brokerage LLC (“WFB”) member FINRA/SIPC, not a bank. The base APY as of 1/30/26 is representative, can change, and requires no minimum. Tim Ferriss, a non-client, receives compensation from WFB for advertising and holds a non-controlling equity interest in the corporate parent of WFB, which creates a conflict of interest. Individual experiences and outcomes will differ. Instant withdrawals may be limited by your receiving firm and other factors. Investment advisory services provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, not bank-guaranteed or FDIC-insured, and may lose value. DISCLAIMER: The content of this episode is for informational purposes only. Neither Sami Inkinen nor Tim Ferriss is a medical professional, and nothing discussed here should be taken as medical advice or a substitute for consultation with a qualified healthcare provider. Timestamps: [00:00] Start. [01:45] How Sami uses 15 minutes every Sunday to outrun the universe. [03:37] Virta: at a thousand employees and counting. [04:15] The 5 a.m. boot-up: cold lake, core work, and emptying the dishwasher. [06:45] Why mood follows movement before the brain even boots up. [11:54] Saying no to 99% of what “normal people” do. [19:29] The weekly architecture. [20:29] Two direct reports: the case for radical subtraction. [21:09] 553 CEO letters and the case for one scalable habit. [32:36] The text-file life plan. [33:32] The 15-year personal plan Sami stumbled into by accident. [34:30] The four-pillar formula for not cracking in 26 years of founder life. [38:20] What “white Japanese people” and beer steins in saunas have in common. [45:55] Smoke saunas, löyly, and the one Finnish word worth knowing. [48:37] The lean, ten-percent-body-fat triathlete who was quietly going prediabetic. [53:07] Why 93% of American adults are metabolically unhealthy. [56:05] Reversing type 2 diabetes the way Virta actually does it. [1:00:17] Most surprising interventions. [1:03:32] The pancreatic cancer trial that bought patients 35% more time. [1:07:02] The McDonald’s protocol: how to reverse diabetes from the drive-thru. [1:16:00] Why GLP-1 adherence collapses and Virta’s doesn’t. [1:21:10] Vegans, tofu, and the hardest macronutrient to get right. [1:25:27] The dose-response curve that lets perfect stop being the enemy of progress. [1:29:32] VO2 max blocks: how Sami trains an 80+ engine without burning out. [1:41:56] Hacking 10% off your running speed in four weeks. [1:46:09] Progressive overload, specificity, and the case against the long ride. [1:50:07] 45 days, three hours, and a contract to keep a marriage afloat. [1:55:27] The lightning strike in the middle of the Pacific that started a family. [2:01:15] The 36-year-old who bought his first car only because his wife made him. [2:05:40] The book recommendation no one saw coming: Trejo. [2:07:51] The PSA: chronic, progressive, and irreversible — three words Sami refuses. [2:11:40] Parting thoughts. * For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast. For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsors Sign up for Tim’s email newsletter (5-Bullet Friday) at tim.blog/friday. For transcripts of episodes, go to tim.blog/transcripts. Discover Tim’s books: tim.blog/books. Follow Tim: Twitter: twitter.com/tferriss Instagram: instagram.com/timferriss YouTube: youtube.com/timferriss Facebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferriss See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.