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3 days ago

Is Brain Inflammation the Missing Link? Brain Inflammation Collaborative & Dr. Ina Stephens | Ep 211

What if some of the most disabling symptoms in EDS, HSD, POTS, MCAS, ME/CFS, and long COVID are being driven by something we still struggle to see on standard testing? In this episode of Bendy Bodies, Dr. Linda Bluestein is joined by guest co-host Dr. Ina Stephens, Associate Director of the UVA Health EDS and Hypermobility Disorder Center, along with Brain Inflammation Collaborative co-founder Christy Jagdfeld and neuroscientist Dr. Megan Fitzgerald. Together, they explore the rapidly evolving science of brain inflammation, including what it actually means, how it differs from conditions like encephalitis or brain edema, and why it may matter in complex multisystem illness. The conversation dives into microglial activation, mast cell involvement in the central nervous system, and the challenge of detecting subtle neuroinflammation in living patients. The guests also discuss emerging research tools, including ultra-high-field MRI, PET ligands, and blood-based extracellular vesicles, that may eventually give clinicians a clearer window into what is happening inside the brain. The group also takes a closer look at the Brain Inflammation Collaborative's Unhide platform, which is collecting real-world, patient-reported data across more than 30 overlapping chronic conditions, including EDS, POTS, MCAS, ME/CFS, and long COVID. Early findings raise important questions about quality of life, symptom burden, the limitations of the Beighton score, and why pediatric research may be especially important. The episode closes with practical implications, including why pacing matters when exercise can worsen symptoms rather than improve them, and what patients and clinicians should watch as this field moves forward. Takeaways “Brain inflammation” can involve subtle processes such as microglial activation and mast cell signaling that may not appear on routine MRI or CT scans. Emerging tools such as ultra-high-field MRI, PET imaging, and blood-based extracellular vesicles may eventually help researchers detect and track neuroinflammation in living patients. The Unhide platform has collected real-world data from thousands of participants with overlapping chronic conditions, offering a new way to study symptom burden and quality of life outside traditional clinical trials. The Beighton score may not reflect functional severity or symptom burden, highlighting the need for better ways to assess hypermobility over time. Pediatric research is urgently needed to understand how these conditions develop and whether earlier recognition could change long-term outcomes. Want more of the Brain Inflammation Collaborative? https://www.unhidenow.org/ https://www.braininflammation.org/ Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.org UVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinic UVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Want more Dr. Linda Bluestein, MD? Website: https://www.hypermobilitymd.com/ YouTube: https://www.youtube.com/@bendybodiespodcast Instagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠ X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠ Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/ Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymd Dr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠⁠https://www\.bendybodiespodcast\.com/⁠⁠. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www\.human-content\.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network Go to AirDoctorPro.com and use promo code BENDY_ to get UP TO $300 off today! FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Chapters: 00:00 Beighton Score Debate00:28 Meet the Guests02:54 Why BIC Was Founded07:22 Defining Brain Inflammation09:44 Biomarkers and Imaging Advances18:12 Unhide Platform and Real World Data25:55 Comorbidities and Survey Cadence31:40 Survey Fatigue Solutions32:49 Tools Beyond Beighton34:16 Research Priorities Wish List35:41 Biomarkers EVs Immune Profiling38:37 Pediatric Focus Early Signs46:34 Building Pediatric Platform53:07 Hacks Resources And Wrap Up Learn more about your ad choices. Visit megaphone.fm/adchoices
6 days ago

NAMI to FNIH: Grand Rounds on Mental Health Innovation w/ Dr. Christine Crawford & Steve Hoffmann

Dr. Mark Mullen welcomes Dr. Christine Crawford, Chief Medical Officer at the National Alliance on Mental Illness (NAMI) and author of You Are Not Alone: For Parents and Caregivers, alongside Steve Hoffmann, Senior Vice President and Chief Preclinical Officer at the Foundation for the National Institutes of Health (FNIH). Dr. Crawford discusses NAMI's mission and its 650 chapters nationwide, the concept of the "distress radius" as a framework for identifying when a child's behavioral changes warrant professional evaluation, and practical strategies for engaging skeptical patients and families through primary care. She also highlights dialectical behavioral therapy (DBT) as a broadly applicable clinical tool and underscores the importance of evidence-based education for patients and caregivers navigating the mental health system. The conversation then shifts to Steve Hoffmann's work at the FNIH, including the newly launching Multimodal Assessment and Phenotyping in Depression (MAPD) study, a longitudinal, multi-site initiative designed to identify biological, clinical, and digital biomarkers associated with depression subtypes. Hoffmann outlines the study's design, including neuroimaging, genetic testing, digital wearables, and patient-reported outcomes, with the goal of moving depression treatment away from a trial-and-error model toward a precision medicine approach. Dr. Crawford and Hoffmann both emphasize the importance of including patient voices in research design, drawing parallels to the foundational impact of the Alzheimer's Disease Neuroimaging Initiative (ADNI) on that field. Takeaways: The "distress radius" framework encourages parents to evaluate whether a child's behavioral changes extend beyond the home into school, social, and extracurricular settings as a signal for further evaluation. NAMI operates 650 chapters nationwide and offers peer-led support groups and educational workshops that clinicians can use as a clinical resource for patients and families. Dialectical behavioral therapy (DBT) skills, including emotional regulation and mindfulness techniques, have broad applicability beyond borderline personality disorder and may benefit general populations. The MAPD study aims to identify multimodal biomarkers, including neuroimaging, genetic, sleep, and digital data, to enable more precise, individualized depression treatment selection. Engaging primary care providers early in the mental health conversation can reduce reliance on long specialist wait lists and help identify safety concerns sooner. SUPPORT OUR PARTNERS: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SimplePractice.com/bootcamp⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (Now with AI documentation! Exclusive 7 day free trial and 50% off four months) Learn more and get transcripts for EVERY episode at https://www.psychiatrybootcamp.com/ For Sales Inquiries & Ad Rates, Please Contact:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sales@Human-Content.Com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Connect with HumanContent on Socials: @humancontentpods Produced by: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Human Content⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices Chapters: 00:00 Meet the Guests 00:58 What NAMI Does 02:31 Why NAMI Matters 04:24 Why Write You Are Not Alone 05:38 Building a Parent Roadmap 09:08 Distress Radius Warning Signs 12:46 NAMI as a Clinical Resource 18:37 Skeptical Patients and Primary Care 23:29 DBT Skills Everyone Needs 26:56 Sponsor Break 29:26 What Is the FNIH 33:32 MAPD Mapping Depression 46:40 Hopes and Takeaways Learn more about your ad choices. Visit megaphone.fm/adchoices
30/06/2025

Assessment of Decisional Capacity: Guidelines, Ethics, and Evidence with Dr. Mira Zein

In this episode, I sit down with Dr. Mira Zein, clinical associate professor at Stanford and co-author of the APA Resource Document on Decisional Capacity Determinations, to break down one of the most frequent and misunderstood consults in psychiatry.We go deep into the Appelbaum–Grisso criteria and discuss how they apply to real-world cases where the answer isn’t always clear. Dr. Zein walks us through difficult scenarios, from life-saving refusals to medically complex delirium cases, highlighting how to think, document, and communicate clearly when capacity is in question. This episode will help you shine on rounds, guide your primary team through their own assessments, and remind you that capacity isn’t about saying “yes” or “no”, it’s about respecting autonomy while protecting patients at their most vulnerable. Takeaways: Capacity is decision-specific and time-specific. It’s not a global judgment, and it can fluctuate with illness, treatment, or environment.The Appelbaum–Grisso framework defines the process. Every evaluation should include communication, understanding, appreciation, and reasoning.Primary teams can and should do their own assessments. Psychiatrists are consultants, not gatekeepers; the best work happens through collaboration.Delirium, dementia, and psychosis are common culprits. Each affects different aspects of capacity, requiring tailored interventions and re-evaluation.Documentation is key. Define the specific decision, describe your assessment of each criterion, and explain your reasoning clearly for the record. Key resources: 1) APA Resource Document on Decisional Capacity Determinations in Consultation-Liaison Psychiatry: A Guide for the General Psychiatrist (2019) 2) Seminal Article on Appelbaum-Grisso Criteria (Appelbaum 1988) 3) Evaluating Capacity: Appelbaum’s Framework Interpreted Diagrammatically (Bari 2023) SUPPORT OUR PARTNERS: ⁠⁠⁠⁠SimplePractice.com/bootcamp⁠⁠⁠⁠ (Now with AI documentation! Exclusive 7 day free trial and 50% off four months) ⁠⁠⁠⁠Beat the Boards⁠⁠⁠⁠ Boot camp listeners now get FREE access to over 4400 exam-style questions) Learn more and get transcripts for EVERY episode at https://www.psychiatrybootcamp.com/ For Sales Inquiries & Ad Rates, Please Contact:⁠⁠⁠Sales@Human-Content.Com⁠⁠⁠ Connect with HumanContent on Socials: @humancontentpods Produced by: ⁠⁠⁠Human Content⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices
07/01/2024

2.7 Bipolar Disorders

Dr. Roger McIntyre, Professor of Psychiatry and Pharmacology at the University of Toronto and Head of the Mood Disorders Psychopharmacology Unit at the University Health Network in Toronto, Canada, introduces us to bipolar disorders. We discuss the key clinical features of bipolar disorders, the relationship between bipolar disorders and circadian rhythm, known pathogenesis, and some first line treatment options. We also contextualize the difference between "type I" and "type II" bipolar disorder, and explore the relationship between bipolar disorder and traumatic life experiences. For more: Bipolar Disorders (Lancet Seminar) SUPPORT OUR PARTNERS: ⁠SimplePractice.com/bootcamp⁠ (Now with AI documentation! Exclusive 7 day free trial and 70% off four months) ⁠Oasis Psychiatry Conferences ⁠(enter code BOOTCAMP at checkout for additional 10% savings) ⁠Beat the Boards⁠ (enter code BOOTCAMP at checkout for addition 10% savings) ⁠CME to Go⁠ (enter code BOOTCAMP at checkout for addition 10% savings) Learn more about your ad choices. Visit megaphone.fm/adchoices
18/01/2024

2.8 Depressive Disorders

Dr. Roger McIntyre, Professor of Psychiatry and Pharmacology at the University of Toronto and Head of the Mood Disorders Psychopharmacology Unit at the University Health Network in Toronto, Canada, returns to introduce depressive disorders. We differentiate normal "low mood" from conditions that warrant a psychiatric diagnosis. We discuss historical subtypes of depression and the current DSM specifiers for major depressive disorder. We review epidemiology, discuss the neurophysiology of depressive disorders, and then dive into treatment options. SUPPORT OUR PARTNERS: ⁠SimplePractice.com/bootcamp⁠ (Now with AI documentation! Exclusive 7 day free trial and 70% off four months) ⁠Oasis Psychiatry Conferences ⁠(enter code BOOTCAMP at checkout for additional 10% savings) ⁠Beat the Boards⁠ (enter code BOOTCAMP at checkout for addition 10% savings) ⁠CME to Go⁠ (enter code BOOTCAMP at checkout for addition 10% savings) Learn more about your ad choices. Visit megaphone.fm/adchoices
4 Aug

Glauc Talk: What's the "Surgeon God Complex"?

We start with Kristin's ever-escalating sleep setup, my childhood bedtime prayer that explicitly included the possibility of dying in my sleep every night from ages zero to eighteen, and the fact that I then did actually die in my sleep, which, in retrospect, really should have been a tell. The midlife crisis hobby conversation covers mountain biking, beekeeping, Bob Ross-style painting, and acting class, which I have already signed up for and fully expect to enjoy. We also invent CampDash, a concierge service that sets up and takes down your campsite so that tent camping becomes something a normal family can do without spending an entire weekend in misery. Someone else needs to run it. The second half is a real one about surgeon personalities, specifically, the thing a TikTok surgeon pointed out that I think actually matters: what gets missed in all the characterizations of surgeon ego and God complex is the constant, pervasive worry that surrounds every case. The operating room is the only time all of that goes away, which is why surgeons "just want to operate", it's not arrogance, it's peace. I'm an ophthalmologist doing 12 cases a day, so I operate on a different scale than a neurosurgeon doing one eight-hour case, but I still have particular things I need exactly right: bed height, head position, the scrub tech anticipating my next move. I talk through how surgical complications require the kind of mentorship that nobody trains you for, and how one of the most humanizing videos I ever made came directly from that experience. Takeaways: Surgeon personalities aren't just ego. They're largely driven by pre- and post-op worry Surgical complications are inevitable and the mental recovery from them is something medicine barely addresses Ophthalmology surgery occupies a different psychological space than high-stakes surgical specialties Making adult friends in your 40s is legitimately hard Bedtime prayers that include the possibility of dying in your sleep probably shouldn't be a nightly ritual for children — To Get Tickets to Wife & Death: You can visit Glaucomflecken.com/live We want to hear YOUR stories (and medical puns)! Shoot us an email and say hi! knockknockhi@human-content.com Can’t get enough of us? Shucks. You can support the show on Patreon for early episode access, exclusive bonus shows, livestream hangouts, and much more! –⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ http://www.patreon.com/glaucomflecken⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Also, be sure to check out the newsletter: https://glaucomflecken.com/glauc-to-me/ If you are interested in buying a book from one of our guests, check them all out here: https://www.amazon.com/shop/dr.glaucomflecken If you want more information on models I use: Anatomy Warehouse provides for the best, crafting custom anatomical products, medical simulation kits and presentation models that create a lasting educational impact. For more information go to Anatomy Warehouse DOT com. Link: https://anatomywarehouse.com/?aff=14 Plus for 15% off use code: Glaucomflecken15 -- A friendly reminder from the G’s and Tarsus: If you want to learn more about Demodex Blepharitis, making an appointment with your eye doctor for an eyelid exam can help you know for sure. Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.EyelidCheck.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for more information. Head to http://www.cozyearth.com and use my code KNOCKKNOCK for an exclusive 20% off. Produced by⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Human Content⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices
20 Aug

Flexibility as a Liability: What Circus Teaches Us about Hypermobility w/ Dr. Emily Scherb (Ep 210)

What if being “naturally flexible” is actually the thing putting you at risk for injury? Dr. Linda Bluestein welcomes back Dr. Emily Scherb, known as The Circus Doc, for a fascinating conversation about what circus performers can teach all hypermobile people about flexibility, strength, joint control, and injury prevention. A physical therapist, researcher, and former circus performer, Dr. Scherb explains why being able to get into an extreme position is not the same as being able to control it—and why impressive range of motion can sometimes mask weakness, instability, or poor load tolerance. The conversation explores how hypermobile bodies function differently at end range, why building strength in the mid-range can be so important, and how to tell the difference between normal training soreness, overtraining, injury, and signs that may point toward an underlying connective tissue disorder. Dr. Scherb and Dr. Bluestein also dig into the psychology of pushing through pain, the way flexibility can become intertwined with identity, the spinal changes documented in contortionists, and why performers may hide injuries when they fear that speaking up could threaten their careers. And while circus provides an extreme example, the lessons apply far beyond the circus world—to dancers, athletes, yogis, gymnasts, and anyone with a body that moves farther than average. Takeaways: More range is not always better. Hypermobility describes how far a joint can move; what matters just as much is how well you can control that range. Getting into a position is not the same as owning it. Extreme flexibility without adequate strength and control can increase stress on joints and surrounding tissues. Hypermobile people often benefit from building strength and motor control in mid-range before progressively challenging end range. Persistent pain, recurrent injuries, instability, or symptoms that seem disproportionate to training may be clues that something more than routine soreness is going on. Contortion offers a striking example of how repeated end-range loading can produce measurable adaptations in the spine. Pain should not have to become severe before someone feels “allowed” to seek care. Creating a culture where performers can address problems early may help protect both health and longevity. The goal for a hypermobile body is not necessarily less flexibility. It is more strength, control, and capacity within the range you already have. Want more of Dr. Emily Scherb? Instagram: https://www.instagram.com/thecircusdoc Website: https://www.thecircusdoc.com Want more Dr. Linda Bluestein, MD? Website: https://www.hypermobilitymd.com/ YouTube: https://www.youtube.com/@bendybodiespodcast Instagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠ X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠ Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/ Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymd Dr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.org UVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinic UVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠⁠https://www\.bendybodiespodcast\.com/⁠⁠. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www\.human-content\.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network Head to http://www.cozyearth.com and use my code BENDY for an exclusive 20% off. Go to AirDoctorPro.com and use promo code BENDY_ to get UP TO $300 off today! FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Chapters: 00:00 Painful Past With Stretching 00:40 Meet The Circus Doc 03:03 How Emily Found Circus Medicine 04:37 What Circus Really Is 06:25 Circus Injuries And End Range 08:55 Hypermobility Flexibility Resilience 33:00 Soreness Vs Overtraining Red Flags 37:52 Hypermobility Soreness Clues 40:13 Yellow Flags vs Red Flags 42:46 Circus Risk and Resilience 47:27 Ignoring Pain Signals 52:08 Building Safer Culture 59:46 Contortion Safety and Strength 01:05:46 Longevity Hacks and Wrap Up Learn more about your ad choices. Visit megaphone.fm/adchoices
10 Aug

Inside Pediatric Emergency Psychiatry with Dr. Megan Schott

Dr. Mark Mullen welcomes Dr. Megan Schott, a child and adolescent psychiatrist specializing in pediatric emergency psychiatry, for a discussion on the escalating boarding crisis affecting youth in psychiatric emergencies. Dr. Schott, who has built pediatric emergency psychiatry programs from the ground up across multiple academic health systems, details how the presence of a trained child psychiatrist in the emergency department can reduce unnecessary admissions by more than half. The conversation examines the definition of boarding, the systemic and financial pressures that limit psychiatric bed availability for children, and the often-overlooked risks of inpatient hospitalization, including social, academic, and long-term consequences for young patients. The episode also features a supervision-style case discussion on managing a challenging conduct disorder presentation, along with a series of rapid-fire "hot takes" covering healthcare parity legislation, the risks social media platforms pose to adolescent safety, and practical guidance for emergency staff without access to a child psychiatrist. Takeaways: Having a trained child and adolescent psychiatrist in the pediatric ED can drastically reduce psychiatric admission rates Boarding is technically defined as remaining in the ED or on a medical floor for eight or more hours after a disposition decision has been made. Inpatient psychiatric admission carries real risks for children, including social stigma, academic disruption, and potential long-term consequences. Mobile crisis teams and psychiatric urgent care models offer promising alternatives to traditional ED-based psychiatric evaluation for lower-acuity cases. Clinicians should openly acknowledge systemic limitations to patients and families rather than overpromising solutions that the current system cannot deliver. SUPPORT OUR PARTNERS: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SimplePractice.com/bootcamp⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (Now with AI documentation! Exclusive 7 day free trial and 50% off four months) Learn more and get transcripts for EVERY episode at https://www.psychiatrybootcamp.com/For Sales Inquiries & Ad Rates, Please Contact:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sales@Human-Content.Com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Connect with Human Content on Socials: @humancontentpodsProduced by: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Human Content⁠ Chapters 00:00 Meet Dr Megan Schott 01:44 Why CAPs in the ED 03:23 What Boarding Means 04:31 Why Beds Are Scarce 07:23 When Not to Admit 13:59 System Fixes and Crisis Teams 17:28 Tough Case Supervision 23:34 Cut Admin Burden 24:47 Medlines Podcast Plug 26:02 CPS Boarding Clash 32:33 Advocacy Beyond Psychiatry 34:02 Parity Law Hot Take 36:01 Social Media Dangers 38:31 ER Tips And Wrap Up Learn more about your ad choices. Visit megaphone.fm/adchoices
12 Jan

Artificial Intelligence and the Future of Psychiatry with Dr. Allen Frances

Psychiatry stands at the threshold of one of its greatest disruptions, the rise of artificial intelligence. In this episode, Dr. Mark Mullen speaks with Dr. Allen Frances, Professor Emeritus and former Chair of Psychiatry at Duke University and Chair of the DSM-IV Task Force, about the clinical, ethical, and societal implications of AI’s rapid entry into mental health care. Drawing from his recent paper in the British Journal of Psychiatry (August 2025), Dr. Frances explores how psychotherapy chatbots have already become the world’s most widely used form of therapy, often beneficial for mild distress but profoundly dangerous for severe mental illness. The discussion examines where chatbots outperform human therapists, where they fail catastrophically, and how clinicians can adapt their practices in anticipation of hybrid human-AI models. Dr. Frances also warns of broader threats, privacy loss, manipulation, and the potential use of AI for political or psychological control This conversation challenges clinicians to approach AI with both curiosity and caution, recognizing its utility while defending the irreplaceable humanity of psychiatric care. Takeaways: AI in psychiatry is no longer hypothetical. Over one billion people now engage with chatbots for therapy or companionship, exceeding all human clinicians combined. Clinical utility is bifurcated. AI can enhance care for mild distress but poses major risks for psychosis, suicidality, and eating disorders. Validation over truth. Chatbots are programmed to please users, not challenge delusions, amplifying psychosis, mania, and self-harm behaviors. Privacy and ethics lag behind innovation. Conversations with chatbots may not be confidential, raising serious HIPAA and legal concerns. Hybrid models are inevitable. Future psychiatrists must integrate AI tools safely, focus on severely ill populations, and preserve the relational aspects machines can’t replicate. References: AI Chatbots: The Good, the Bad, and the Ugly (Frances' column in Psychiatric Times): https://www.psychiatrictimes.com/series/ai-chatbots-the-good-the-bad-and-the-ugly Warning: AI Chatbots will soon dominate psychotherapy (Frances' feature in the British Journal of Psychiatry): https://www.cambridge.org/core/services/aop-cambridge-core/content/view/DBE883D1E089006DFD07D0E09A2D1FB3/S0007125025103802a.pdf/warning_ai_chatbots_will_soon_dominate_psychotherapy.pdf SUPPORT OUR PARTNERS: ⁠⁠⁠⁠⁠SimplePractice.com/bootcamp⁠⁠⁠⁠⁠ (Now with AI documentation! Exclusive 7 day free trial and 50% off four months) ⁠⁠⁠⁠⁠Beat the Boards⁠⁠⁠⁠⁠ Boot camp listeners now get FREE access to over 4400 exam-style questions) Go to Cozy Earth now for a Buy One Get One Free Pajama Offer from 1/25-2/8! Yes, go to cozyearth.com they are doing a BOGO pajama promo. Just use my Code: BOOTCAMPBOGO Learn more and get transcripts for EVERY episode at https://www.psychiatrybootcamp.com/ For Sales Inquiries & Ad Rates, Please Contact:⁠⁠⁠⁠Sales@Human-Content.Com⁠⁠⁠⁠ Connect with HumanContent on Socials: @humancontentpods Produced by: ⁠⁠⁠⁠Human Content⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices
09/06/2025

Behavioral and Psychological Symptoms of Dementia: A Clinical Guide with Dr. George Grossberg

In this episode, I talk with Dr. George Grossberg, a pioneer in geriatric psychiatry, about the neuropsychiatric symptoms of dementia and what they look like, why they happen, and how to approach them with empathy and strategy. We walk through the most common behavioral disturbances in dementia, including apathy, depression, psychosis, and agitation. Dr. Grossberg shares how to think through these cases, when to reach for medication, when to hold back, and how to anchor every decision in an understanding of who the patient truly is. Takeaways: Neuropsychiatric symptoms are nearly universal in dementia. Expect them, don’t be surprised by them.Apathy and depression aren’t the same. Treating apathy like depression often fails; gentle engagement works better than antidepressants.Start with environment and empathy. Music, structure, exercise, and caregiver education should come before medication.Use medication sparingly and strategically. When needed, match the drug to the symptom, and always reassess risk versus relief.Knowing the person changes everything. Understanding a patient’s history, preferences, and rhythms is as therapeutic as any pharmacologic plan. Selected References: ⁠Progress in Pharmacologic Management of Neuropsychiatric Syndromes in Neurodegenerative Disorders: A Review (Cummings 2024) Neuropsychiatric Symptoms of Dementia and their nonpharmacological and pharmacological management (Tampi 2022)⁠ Management of BPSD Algorithm (Chen with Osser 2021)⁠ Atypical Antipsychotics for Aggression and Psychosis in Alzheimer's disease (Ballard 2006) Efficacy and Adverse Effects of Atypical Antipsychotics for Dementia (Schneider 2006) Sequential Drug Treatment Algorithm for Agitation and Aggression in Alzheimer's and Mixed Dementia (Davies 2018) SUPPORT OUR PARTNERS: ⁠⁠⁠⁠SimplePractice.com/bootcamp⁠⁠⁠⁠ (Now with AI documentation! Exclusive 7 day free trial and 50% off four months) ⁠⁠⁠⁠Beat the Boards⁠⁠⁠⁠ Boot camp listeners now get FREE access to over 4400 exam-style questions) Learn more and get transcripts for EVERY episode at https://www.psychiatrybootcamp.com/ For Sales Inquiries & Ad Rates, Please Contact:⁠⁠⁠Sales@Human-Content.Com⁠⁠⁠ Connect with HumanContent on Socials: @humancontentpods Produced by: ⁠⁠⁠Human Content⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

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