Dr. Riley Kirk welcomes Kyle Boyar to the Bioactive Podcast for an in-depth conversation on cannabis testing, mycotoxins, analytical chemistry, biohacking, and the evolving cannabis industry. Drawing from over a decade of experience in cannabis science, Kyle shares insights from his work across leading cannabis testing laboratories, academic institutions, and regulatory spaces. The discussion explores how cannabis testing has evolved over the years, the importance of accurate lab data, and the real-world challenges surrounding contamination, safety standards, and consumer trust. They also dive into the science of mycotoxins, microbial contamination, heavy metals, and how environmental conditions can impact cannabis quality and safety. The conversation examines the complexities of cannabis regulation, inconsistencies between state testing systems, and the role of analytical chemistry in improving industry standards. Additionally, they explore cannabis biohacking, cannabinoids, terpenes, creativity, and the relationship between cannabis use and cognitive performance. The dialogue further highlights the importance of scientific literacy within the cannabis industry, education for consumers, and the need for evidence-based discussions around cannabis safety and wellness. Finally, they touch on the future of cannabis science, emerging technologies in testing, and how researchers can help shape a more transparent and informed cannabis landscape. This is a conversation for anyone interested in cannabis science, product safety, laboratory testing, biohacking, analytical chemistry, and the future of evidence-based cannabis education. Chapters 00:00 Magnesium and Cortisol Timing 00:46 Meet the Guest Kyle Boyar 02:08 Biohacking 03:47 Daily Supplements and Omega-3 Quality 07:28 How to Vet Supplements 09:47 Caffeine Plus L-Theanine Focus Stack 13:59 Nighttime Calm Magnesium and CBN 21:04 Ashwagandha for Stress and Cortisol 24:31 Hangover Defense DHM and NAC 28:47 ECS Supplements PEA and OEA Reality Check 31:22 Cannabis Mycotoxins Testing Basics 32:54 Why Mycotoxin Failures Are Rare 34:32 Fusarium Focus and Field PCR 35:47 LAMP Contamination Reality 36:25 Fusarium Mycotoxins Explained 37:47 Extracts and CBD Findings 39:49 New Studies and Blind Spots 43:06 Ten State Compliance Data 44:24 Remediation Limits and DNA 50:21 Fixing Testing Trust Issues 53:10 THC Dopamine Basics 55:58 Creativity Dose Sweet Spot 01:00:28 Addiction Tolerance and Vapes 01:02:29 Schizophrenia Risk Mechanisms 01:04:04 Thalamus Filter and Reality 01:06:56 Heart Risks and Wrap Up Connect with Kyle Boyar Follow Kyle’s work in cannabis science, analytical chemistry, and education through his speaking engagements, scientific organizations, and industry collaborations. LinkedIn: https://www.linkedin.com/in/kyleboyar IG: https://www.instagram.com/canna_kybo Want Exclusive Content and ad-free episodes? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Sign Up for Emails! www.AppliedPharmacognosy.org Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices