CareTalk: Healthcare. Unfiltered.

CareTalk: Healthcare. Unfiltered.

CareTalk: Healthcare. Unfiltered. is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy. Visit us at www.CareTalkPodcast.com

  1. The Business & Science Behind the GLP-1 Boom

    5d ago

    The Business & Science Behind the GLP-1 Boom

    Send us Fan Mail GLP-1 drugs have produced some of the most consistent weight loss results medicine has ever seen. The business of actually getting them to patients is a different story entirely. David E. Williams, President of Health Business Group, and John Driscoll, Chairman of UConn Health, break down the CVS Caremark formulary reversal on CareTalk, examining what it reveals about the economics of GLP-1 coverage, and why emerging clinical research on cancer, long COVID, and addiction may push these drugs far beyond their original indication. 🎙️⚕️ABOUT CARETALK CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy. ✨THIS VIDEO BROUGHT YOU BY: At PIM Health, we’re building real-time payment infrastructure where providers don’t wait weeks to get paid, patients don’t leave without knowing exactly what they owe, and employers stop flying blind on their own plan spend. AR burden, gone. Surprise bills, gone. Prior auth delays, gone. Denials and appeals, gone.  Learn what we’re building here GET IN TOUCH Follow CareTalk on LinkedIn Become a CareTalk sponsor Guest appearance requests Visit us on the web Support the show ⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

    24 min
  2. Jun 17

    Why We Can Never Have Enough Doctors

    Send us Fan Mail Six million healthcare workers are missing today. By 2030, that number reaches 10 million. No amount of training will ever close that gap. In this clip from our episode “Is AI the New Dr. Google?”, host David E. Williams and Bertalan Mesko, Director of the Medical Futurist Institute, break down why the healthcare worker shortage is a mathematical problem that only advanced technology can solve. Listen to the full episode here 🎙️⚕️ABOUT DR. BERTALAN MESKO Dr. Bertalan Meskó, MD, PhD, widely known as "The Medical Futurist," is a leading global expert on healthcare technology. He serves as the Director of The Medical Futurist Institute and is a Private Professor at Semmelweis University in Budapest, Hungary. With a background as a physician and a PhD in genomics, Dr. Meskó focuses on how tools like artificial intelligence, wearable devices, and robots can improve modern medicine. He has delivered hundreds of keynote presentations at top institutions like Harvard and Stanford. He is also a bestselling author who has been featured by major media outlets such as CNN, TIME, and National Geographic. 🎙️⚕️ABOUT HEALTH BIZ PODCAST HealthBiz is a CareTalk podcast that delivers in-depth interviews on healthcare business, technology, and policy with entrepreneurs and CEOs. Host David E. Williams — president of the healthcare strategy consulting boutique Health Business Group — is also a board member, investor in private healthcare companies, and author of the Health Business Blog. Known for his strategic insights and sharp humor, David offers a refreshing break from the usual healthcare industry BS. Need a Strategy Partner? For over 20 years, Health Business Group has helped healthcare software companies, tech-enabled services businesses, life sciences companies, and payers make smarter strategic decisions. Led by podcast host David Williams, the firm advises clients on sharpening AI positioning, entering new segments, and building commercial strategies for value-based care. See examples of our work at healthbusinessgroup.com/ GET IN TOUCH Follow CareTalk on LinkedIn Become a CareTalk sponsor Guest appearance requests Visit us on the web Support the show ⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

    5 min
  3. The Future of Medicine Is Already Here w/ Bertalan Mesko, The Medical Futurist Institute

    Jun 12

    The Future of Medicine Is Already Here w/ Bertalan Mesko, The Medical Futurist Institute

    Send us Fan Mail The World Health Organization projects a global shortage of 10 million healthcare workers by 2030. No training pipeline can close that gap. The only path forward runs through technology. Dr. Bertalan Meskó, Founder & Director of the Medical Futurist Institute, joins host David E. Williams to discuss why digital health is first and foremost a cultural transformation rather than a technological one, and why the most important thing any health system leader can do right now is learn how to use AI as the connective interface between an increasingly complex ecosystem of tools, patients, and clinical teams. 🎙️⚕️ABOUT DR. BERTALAN MESKO Dr. Bertalan Meskó, MD, PhD, widely known as "The Medical Futurist," is a leading global expert on healthcare technology. He serves as the Director of The Medical Futurist Institute and is a Private Professor at Semmelweis University in Budapest, Hungary. With a background as a physician and a PhD in genomics, Dr. Meskó focuses on how tools like artificial intelligence, wearable devices, and robots can improve modern medicine. He has delivered hundreds of keynote presentations at top institutions like Harvard and Stanford. He is also a bestselling author who has been featured by major media outlets such as CNN, TIME, and National Geographic. 🎙️⚕️ABOUT HEALTH BIZ PODCAST HealthBiz is a CareTalk podcast that delivers in-depth interviews on healthcare business, technology, and policy with entrepreneurs and CEOs. Host David E. Williams — president of the healthcare strategy consulting boutique Health Business Group — is also a board member, investor in private healthcare companies, and author of the Health Business Blog. Known for his strategic insights and sharp humor, David offers a refreshing break from the usual healthcare industry BS. Need a Strategy Partner? For over 20 years, Health Business Group has helped healthcare software companies, tech-enabled services businesses, life sciences companies, and payers make smarter strategic decisions. Led by podcast host David Williams, the firm advises clients on sharpening AI positioning, entering new segments, and building commercial strategies for value-based care. See examples of our work at healthbusinessgroup.com/ ✨THIS VIDEO BROUGHT YOU BY: At PIM Health, we’re building real-time payment infrastructure where providers don’t wait weeks to get paid, patients don’t leave without knowing exactly what they owe, and employers stop flying blind on their own plan spend. AR burden, gone. Surprise bills, gone. Prior auth delays, gone. Denials and appeals, gone.  Learn what we’re building here GET IN TOUCH Follow CareTalk on LinkedIn Become a CareTalk sponsor Guest appearance requests Visit us on the web Support the show ⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

    48 min
  4. Jun 10

    Why Insulin Never Reaches the Liver

    Send us Fan Mail The liver is the only organ in the body that can release stored glucose to prevent low blood sugar. So why has injected insulin never been able to reach it? In this clip from our episode “Finding a Solution for GLP-1 Side Effects”, host David E. Williams and Bob Geho, Founder and CEO of Diasome, break down the biological gap at the heart of diabetes treatment and how a father's decades of research into liver-targeted insulin delivery became the founding idea behind Diasome. Listen to the full episode here 🎙️⚕️ABOUT BOB GEHO Bob Geho is the Chief Executive Officer of Diasome Pharmaceuticals, a clinical-stage biopharmaceutical company developing portal-hepatic -targeted therapies designed to act at the source of metabolic regulation. Under his leadership, Diasome is advancing its proprietary Hepatocyte-Directed Vesicle (HDV) platform, which targets liver hepatocytes and the portal hepatic region, where metabolic control is centered. The company's lead clinical program, HDV-Insulin, applies this approach to insulin therapy — grounded in the principle that therapies working with the body's natural physiology may produce meaningfully better outcomes. The HDV platform is also being explored across GLP-1 and serotonin programs. Bob's work in hepatic-directed drug delivery spans more than three decades, including helping lead the first successful human clinical study of liver-targeted insulin in Type 1 diabetes patients. He co-founded Diasome in 2004 and has since guided the company through multiple rounds of financing and into clinical development. He also co-founded SDG, Inc., a Cleveland-based holding company that has supported the creation of multiple life sciences startups and strategic partnerships. He holds an MBA from Case Western Reserve University. 🎙️⚕️ABOUT HEALTH BIZ PODCAST HealthBiz is a CareTalk podcast that delivers in-depth interviews on healthcare business, technology, and policy with entrepreneurs and CEOs. Host David E. Williams — president of the healthcare strategy consulting boutique Health Business Group — is also a board member, investor in private healthcare companies, and author of the Health Business Blog. Known for his strategic insights and sharp humor, David offers a refreshing break from the usual healthcare industry BS. Need a Strategy Partner? For over 20 years, Health Business Group has helped healthcare software companies, tech-enabled services businesses, life sciences companies, and payers make smarter strategic decisions. Led by podcast host David Williams, the firm advises clients on sharpening AI positioning, entering new segments, and building commercial strategies for value-based care. See examples of our work at healthbusinessgroup.com/ GET IN TOUCH Follow CareTalk on LinkedIn Become a CareTalk sponsor Guest appearance requests Visit us on the web Support the show ⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

    3 min
  5. Targeting the Root Causes of Metabolic Disease w/ Bob Geho, Founder & CEO, Diasome

    Jun 7

    Targeting the Root Causes of Metabolic Disease w/ Bob Geho, Founder & CEO, Diasome

    Send us Fan Mail Every year, one in five adults with Type 1 diabetes experiences a dangerous drop in blood sugar that renders them unable to treat themselves. These severe hypoglycemic events are still happening, even though many patients now use continuous glucose monitors and automated insulin pumps. Why has this trade-off between long-term A1C control and dangerous sugar crashes persisted for over 30 years? Bob Geho, Founder and CEO of Diasome, joins host David E. Williams to unpack the results of the company’s 200+ patient Phase 2B OPTI-2 trial of HDV™ insulin. The study was presented recently at the American Diabetes Association meeting in New Orleans. In the trial, five patients using standard insulin experienced severe hypoglycemic events. This compares with zero such events among patients receiving HDV™ insulin. Meanwhile, HDV™ insulin matched standard-of-care A1C control. Bob also shares how the HDV platform is being studied for its potential to reduce side effects in GLP-1 therapy and to address insulin resistance, considered the root cause of Type 2 Diabetes. 🎙️⚕️ABOUT BOB GEHO Bob Geho is the Chief Executive Officer of Diasome Pharmaceuticals, a clinical-stage biopharmaceutical company developing portal-hepatic -targeted therapies designed to act at the source of metabolic regulation. Under his leadership, Diasome is advancing its proprietary Hepatocyte-Directed Vesicle (HDV) platform, which targets liver hepatocytes and the portal hepatic region, where metabolic control is centered. The company's lead clinical program, HDV-Insulin, applies this approach to insulin therapy — grounded in the principle that therapies working with the body's natural physiology may produce meaningfully better outcomes. The HDV platform is also being explored across GLP-1 and serotonin programs. Bob's work in hepatic-directed drug delivery spans more than three decades, including helping lead the first successful human clinical study of liver-targeted insulin in Type 1 diabetes patients. He co-founded Diasome in 2004 and has since guided the company through multiple rounds of financing and into clinical development. He also co-founded SDG, Inc., a Cleveland-based holding company that has supported the creation of multiple life sciences startups and strategic partnerships. He holds an MBA from Case Western Reserve University. 🎙️⚕️ABOUT HEALTH BIZ PODCAST HealthBiz is a CareTalk podcast that delivers in-depth interviews on healthcare business, technology, and policy with entrepreneurs and CEOs. Host David E. Williams — president of the healthcare strategy consulting boutique Health Business Group — is also a board member, investor in private healthcare companies, and author of the Health Business Blog. Known for his strategic insights and sharp humor, David offers a refreshing break from the usual healthcare industry BS. Need a Strategy Partner? For over 20 years, Health Business Group has helped healthcare software companies, tech-enabled services businesses, life sciences companies, and payers make smarter strategic decisions. Led by podcast host David Williams, the firm advises clients on sharpening AI positioning, entering new segments, and building commercial strategies for value-based care. See examples of our work at healthbusinessgroup.com/ GET IN TOUCH Follow CareTalk on LinkedIn Become a CareTalk sponsor Guest appearance requests Visit us on the web Support the show ⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

    37 min
  6. Can Healthcare Claims Be Adjudicated in Real-Time? w/ Don Peterson, Founder & CEO, PIM Health

    Jun 3

    Can Healthcare Claims Be Adjudicated in Real-Time? w/ Don Peterson, Founder & CEO, PIM Health

    Send us Fan Mail American hospitals now spend nearly $2 on administrative overhead for every dollar that touches direct patient care. Insurers earn billions in float by sitting on claims for weeks, providers borrow money just to stay liquid, and patients open bills for visits they barely remember. Don Peterson, Founder and CEO of PIM Health, joins host David E. Williams to discuss why healthcare's payment system is working exactly as it was designed to work, and how real-time claims adjudication at the point of care could eliminate prior authorization as it currently exists, cut administrative overhead from 12 to 15 percent down to 2 to 3 percent, and return hundreds of billions of dollars in waste back to patients, providers, and plan sponsors. 🎙️⚕️ABOUT DON PETERSON Don Peterson is a healthcare entrepreneur and technology executive with over 30 years of experience building and scaling companies across technology and healthcare. He held senior roles at AMD during the semiconductor boom, founded DeskStation Technology in 1990 (acquired by Samsung), and in 2012 founded IVX Health, building the operating model for ambulatory infusion centers from the ground up. Under subsequent leadership, IVX Health scaled to 150+ locations nationally and completed a change-of-control transaction in 2024 at a valuation exceeding one billion dollars. Peterson also launched and operationalized ambulatory infusion clinics in Saudi Arabia from 2020 to 2024. He is currently the founder of PIM Health Corp., a healthcare technology company developing real-time claims adjudication and payment infrastructure designed to replace the batch-processing architecture that has defined healthcare payment settlement for decades. Peterson publishes healthcare policy analysis and industry commentary on Substack and hosts the podcast Divided Attention, covering healthcare, technology, and policy. 🎙️⚕️ABOUT PIM HEALTH PIM Health is a healthcare technology company building real-time claims adjudication and payment infrastructure designed to replace the batch-processing architecture that has defined healthcare payment settlement for decades. Founded by Don Peterson, whose experience scaling IVX Health to a billion-dollar acquisition gave him a firsthand view of how broken healthcare payment actually is, PIM is built around a simple insight: providers who get paid in 24 hours instead of 90 days, members who never receive a surprise bill, and self-insured employers who can see real-time claims activity will drive demand faster than any direct sales effort. The infrastructure investment by payers follows that demand, not the other way around. At PIM Health, we’re building real-time payment infrastructure where providers don’t wait weeks to get paid, patients don’t leave without knowing exactly what they owe, and employers stop flying blind on their own plan spend. AR burden, gone. Surprise bills, gone. Prior auth delays, gone. Denials and appeals, gone. Learn what we’re building at pim.health 🎙️⚕️ABOUT CARETALK CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy.  GET IN TOUCH Follow CareTalk on LinkedIn Become a CareTalk sponsor Guest appearance requests Visit us on the web Support the show ⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

    38 min
  7. Jun 3

    How Digital Interventions Transform Mental Health

    Send us Fan Mail What if the tools patients use between therapy sessions mattered more than the sessions themselves? In this clip from our episode “Fixing the Access Crisis In Mental Health”, host John Driscoll and Mark Frank, Co-Founder and CEO of SonderMind, break down how a fully integrated platform combining 80 digital interventions with an AI coach is producing outcomes up to 275% better than traditional therapy alone. Listen to the full episode here 🎙️⚕️ABOUT MARK FRANK As the CEO and co-founder of SonderMind, I lead a fast-growing and compassionate team whose mission is to redesign behavioral health to increase access, expand utilization and improve clinical outcomes. Our focus is to democratize behavioral healthcare for both patients and practitioners, by making it easy to access therapists with the right expertise, making it convenient by offering online or in person treatment, and making it affordable by matching patients with highly qualified providers that deliver the most effective care. I believe in leading with transparency, empathy, and courage, and my passion is to build an organization that has a positive and transformative effect on the field of behavioral health and ultimately the entire healthcare ecosystem. Prior to founding SonderMind in 2015, I helped found three other successful ventures, including Next Oncology, TermScout and SafeImageMD. Prior to my career as an entrepreneur, I worked in healthcare investment banking at Morgan Stanley, as well as time with Lehman Brothers and CDI Global. Prior to my business career, I served as an officer in the US Army. During and after that time in the military, I saw friends and colleagues return from deployments and struggle to access appropriate mental health care. This experience shaped and strengthened my commitment to enhancing access to therapy to improve and enrich people’s lives. I have a Bachelor's Degree in Computer Science from the United States Military Academy at West Point, a Masters in Computer Information Systems from the University of Phoenix, a Masters of Engineering Management from Northwestern University, and an MBA in Finance and Operations from the Kellogg School of Management at Northwestern University. 🎙️⚕️ABOUT CARETALK CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy.  GET IN TOUCH Follow CareTalk on LinkedIn Become a CareTalk sponsor Guest appearance requests Visit us on the web Support the show ⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

    4 min

About

CareTalk: Healthcare. Unfiltered. is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy. Visit us at www.CareTalkPodcast.com

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