Smart Medicine

Dr. Ali Fatemi
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Smart Medicine explores how AI, physics, and human insight are reshaping the future of healthcare. Hosted by Dr. Ali Fatemi, a medical physicist and entrepreneur, the show dives into the latest innovations in medical imaging, oncology, and digital health. Each episode brings conversations with clinicians, scientists, and innovators to uncover how new technologies are transforming patient care — and what challenges still remain. Whether you’re a healthcare professional, researcher, startup founder, or simply curious about the future of medicine.

  1. 3D AGO

    Radiation Oncology Leadership in the AI Era | Dr. Percy Lee (City of Hope)

    Today’s guest is Dr. Percy Lee, Senior Physician Executive and Medical Director of Radiation Oncology (Orange County) at City of Hope, and Vice Chair of Clinical Research. Dr. Lee is a nationally recognized leader in radiation oncology, with extensive experience building and scaling clinical programs, integrating research into practice, and expanding access to high-quality cancer care. His leadership journey includes key roles at MD Anderson and UCLA, where he helped shape one of the leading SBRT and residency programs in the U.S. In this conversation, we explore: What it really takes to build and scale successful radiation oncology programs How to separate meaningful innovation from hype in cancer care Where AI and smart technologies will realistically impact clinical workflows How physician leadership has evolved—and what skills matter most today The biggest opportunities and risks facing radiation oncology Practical advice for trainees and early-career clinicians aiming to lead responsibly This discussion is a clear look at how leadership, technology, and clinical reality must align to drive real impact in cancer care.

    43 min

  2. MAR 28

    Smart Medicine Podcast | Prof. Nico Van Den Berg — Computational MRI, AI, and the Future of Image-Guided Therapy

    In this episode, I speak with Professor Nico Van Den Berg, Director of the Centre of Image Science at UMC Utrecht and Scientific Co-Lead of the IMAGINE Consortium—one of the leading voices at the intersection of MR physics, computational imaging, and AI-driven clinical translation. We explore how MRI is evolving from a hardware-driven modality into a computational and intelligent system, and what this means for the future of diagnostics and therapy. Key topics we discuss: • From MRI physics to computational imaging How Nico’s journey shaped his vision for integrating physics, computation, and clinical workflows. • What “computational imaging” really means in MRI How reconstruction, acquisition, and processing are being redefined—and where this creates real clinical impact. • MR-Linac: promise vs reality Why it’s one of the most advanced technologies in radiation oncology—and why adoption still faces barriers. • AI and autonomous imaging What is realistic in the next 5–10 years, where AI is already delivering value today, and the risks of using AI without strong physics grounding. • Image-guided interventions & the IMAGINE Consortium The infrastructure and computational challenges behind making advanced interventions scalable and clinically relevant. • RF engineering, safety, and translation to clinic Why safety, implants, and system-level understanding remain critical as MRI moves deeper into therapy. • The future of MRI Will intelligence reshape hardware, pulse sequences, and workflows? What does this mean for adaptive radiotherapy? • Advice for the next generation What young physicists should focus on to stay relevant in an AI-driven era. This conversation highlights a central theme: AI alone is not enough—true progress in medical imaging requires deep integration of physics, computation, and clinical insight. #SmartMedicine #MedicalPhysics #MRI #AIinMedicine #ComputationalImaging #MRLinac #Radiology #RadiationOncology #ImageGuidedTherapy #DigitalHealth

    37 min

  3. MAR 23

    AI, Practice Shift, and the Future of Medical Physics – Dr. Mahesh

    Dr. Mahesh, Board Chair of AAPM, joins the Smart Medicine Podcast to discuss how medical physics is evolving in the era of AI. We explore: • The shift beyond traditional QA • AI in clinical workflows • Future skills for physicists • Training and education gaps • Patient safety in autonomous systems A forward-looking conversation on the future of the field.

    52 min

  4. MAR 13

    Smart Medicine Podcast | Inside the Evolution of Modern Radiation Therapy with Kevin Brown (Elekta)

    Smart Medicine Podcast – Episode: Kevin Brown In this episode of the Smart Medicine Podcast, Ali Fatemi sits down with Kevin Brown, retired Distinguished Scientist at Elekta, following an extraordinary 45-year career helping shape modern radiation therapy technologies. Kevin has played a key role in advancing radiotherapy systems—from early hardware and imaging innovations to leading global scientific research programs that helped translate technology into real clinical impact. In this conversation, we explore: • The evolution of radiation therapy technology over four decades • How engineering innovations become scalable clinical systems • Lessons from industry–academia collaboration • Where complexity helps—or hinders—clinical progress • Advice for physicists and engineers entering the medical technology industry • The future of radiation oncology innovation This discussion offers a rare perspective from someone who helped build many of the systems that define modern radiation therapy today. 🎙 Host: Ali Fatemi Founder – SpinTecx | PrecisionMRI.ai Host – Smart Medicine Podcast

    51 min

  5. MAR 4

    Smart Medicine Podcast | Thomas “Rock” Mackie | Innovation, Entrepreneurship & the Future of Radiation Therapy

    In this episode of the Smart Medicine Podcast, I speak with Thomas “Rock” Mackie, medical physicist, entrepreneur, and Professor of Medical Physics at the University of Wisconsin–Madison. Dr. Mackie is one of the key innovators in modern radiation medicine. As a co-founder of TomoTherapy and founder of Leo Cancer Care, he has helped translate medical physics research into technologies that have significantly influenced radiation therapy practice worldwide. In this conversation, we discuss: • The journey from academic medical physics to entrepreneurship and leadership • What distinguishes technologies that truly change clinical practice • The role of boards and governance in guiding innovation • How AI, automation, and data-driven tools are shaping the future of healthcare • Advice for physicists and clinicians who want to build and lead innovation This discussion explores how medical physicists can play a larger role in shaping the future of healthcare technology and patient care. Smart Medicine Podcast features conversations with leading scientists, physicians, and innovators shaping the future of medicine. #SmartMedicinePodcast #MedicalPhysics #RadiationOncology #MedTech #HealthInnovation #SmartMedicinePodcast #MedicalPhysics #AIinMedicine #PrecisionMRI #SpinTecx #MRI #MRPhysics #QuantitativeImaging #MRIGuidedRT #ImagingScience #RadiologyInnovation #GeometricDistortion #ImagingQA #HealthcareAI #ArtificialIntelligence #AIinRadiology #ClinicalAI #MedicalImagingAI #PhysicsAndAI #DigitalHealth #SaMD #RadiationOncology #MedicalPhysicist #CancerTechnology #Radiotherapy #ClinicalTranslation #PatientSafety #OncologyInnovation #HealthcareInnovation #MedTechStartup #PhysicianEntrepreneur #ScientificLeadership #TranslationalScience #HealthTech #SmartMedicinePodcast #MedicalPhysics #AIinMedicine #MRI #RadiationOncology #HealthcareInnovation #ClinicalAI #MedTech #AAPM #COMP

    1h 8m

  6. FEB 26

    Smart Medicine Podcast | Dr. Sasa Mutic — Shaping the Future of Radiation Oncology, Imaging, and AI

    Dr. Sasa Mutic, President of Radiation Oncology Solutions at Varian Medical Systems, joins the Smart Medicine Podcast to discuss leadership, AI, and the future of radiation oncology. We explore the transition from academia to global industry leadership, the real impact of automation, and how medical physicists can shape — not fear — the future of intelligent healthcare systems.

    49 min

  7. FEB 17

    AI Medical Devices & FDA Pathways: 510(k), De Novo & SaMD Strategy | Smart Medicine Podcast with Dr. Yujan Shrestha at Innolitics

    In this episode of the Smart Medicine Podcast, Dr. Ali Fatemi speaks with Dr. Yujan Shrestha, MD, physician–engineer and Partner at Innolitics, about AI medical device regulation and clinical validation. We discuss FDA pathways, including 510(k), De Novo, and Breakthrough programs, common regulatory pitfalls in AI/ML software as a medical device (SaMD), post-market model updates, and how AI will reshape clinical decision-making in oncology and beyond. Smart Medicine explores the intersection of AI, medical imaging, regulation, and healthcare innovation. AI in healthcare regulated AI medical device innovation clinical AI validation FDA medical devices AI in oncology digital health regulation

    52 min

  8. FEB 13

    AI, Low-Field MRI & Quantitative Imaging | Smart Medicine Podcast with Dr. Matthew Rosen & Dr. Michael Hoff

    In this episode of the Smart Medicine Podcast, Dr. Ali Fatemi speaks with Dr. Matthew Rosen of Harvard Medical School and Dr. Michael Hoff of UCSF about low-field MRI, quantitative imaging, AI-driven reconstruction, and the future of smart imaging systems. We explore reproducibility challenges, hybrid physics–AI approaches, and the evolving role of medical physicists in clinical AI validation.

    1h 14m
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About

Smart Medicine explores how AI, physics, and human insight are reshaping the future of healthcare. Hosted by Dr. Ali Fatemi, a medical physicist and entrepreneur, the show dives into the latest innovations in medical imaging, oncology, and digital health. Each episode brings conversations with clinicians, scientists, and innovators to uncover how new technologies are transforming patient care — and what challenges still remain. Whether you’re a healthcare professional, researcher, startup founder, or simply curious about the future of medicine.

Information

  • Creator
    Dr. Ali Fatemi
  • Years Active
    2025 - 2026
  • Episodes
    16
  • Rating
    Clean
  • Copyright
    © Dr. Ali Fatemi
  • Show Website
    Smart Medicine

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