High Performance Longevity

Nick Urban | Longevity, Biohacking, & Performance

High Performance Longevity is the show for folks dedicated to maximizing their overall quality of life. I am your host Nick Urban and I’m bringing you the best minds handpicked from cognitive enhancement, BioHarmonization (biohacking 3.0), fitness, ancestral health, herbal medicine, spirituality, personal development, longevity, supplementation, and meditation. Each episode deconstructs their world-class work into tangible steps for you to look, feel, and perform your best. We’ll leave no stone unturned whether modern topics like peptides and nootropics, or ancient systems like Ayurveda and Traditional Chinese Medicine. You’ll learn how to re-sculpt your body, boost energy levels, improve athletic performance, and gain mental clarity. Nick Urban is a certified Chek Practitioner, biohacker, performance coach, and has spent a decade studying high performance. Health nut or not, HPL will fill your toolbox with products, tactics, knowledge, and resources needed to live at your maximum potential. Previously, this show was called Mind Body Peak Performance.

  1. 1 DAY AGO

    #259 The Neuroscience of Why Your Healthy Habits Don't Stick & The 8C Framework That Makes Them Last | Dr. Lisa Riegel

    Dr. Lisa Riegel reveals why 85% of New Year's resolutions fail by week 2 and the brain science that makes change actually stick. The NeuroWell Framework explains how your thalamus (Harold) and amygdala (Bob) hijack decision-making and what to do about it. In this conversation, Dr. Lisa A. Riegel, breaks down the neuroscience of self-regulation, the 4 states of awake, a 30-minute relaxation protocol, and her 8C Commitment Framework for making personal change last. Meet our guest Dr. Lisa A. Riegel is a leadership strategist, educator, and author who helps organizations use neuroscience to build cultures of engagement, wellbeing, and sustainable change. She's the creator of the NeuroWell Framework and author of NeuroWell. With over 2 decades of experience across education, nonprofit, and community-based organizations, she translates complex brain science into practical tools leaders can use. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Your brain is a corporation: the thalamus (Harold) handles data, the amygdala (Bob) runs security, your prefrontal cortex is the CEO 85% of Americans ditch their New Year's resolutions by week 2 A 30-minute relaxation alarm trains the vagus nerve to auto-regulate The "solution to pollution is dilution": you can't erase negative brain filters, but you can crowd them out Social anxiety is misdiagnosed 98.7% of the time, per NIH data Dr. Riegel cites Roughly 30% of Americans have undiagnosed blood sugar issues masquerading as mental health disorders AI cognitive offloading atrophies the exact brain region responsible for character, morals, and consciousness Celebration is the #1 underrated ingredient in the 8C Commitment Framework for sustained change    Episode highlights 00:00 Intro 02:31 Your brain is a company (meet Harold & Bob) 05:12 The 4 states of awake: calm, alert, alarm, fear 07:53 Which protective filters to keep vs. dilute 08:11 Building your trigger sheet 13:08 The 30-minute relaxation alarm 16:24 Why 85% of goals fail by week 2 20:49 Why your proprioceptive system is broken 24:11 AI anxiety and the local expert crisis 34:10 The vault: workplace venting done right 36:01 Chronic stress, autoimmune disease & blood sugar 37:18 Social anxiety is misdiagnosed 98.7% of the time 42:28 Creativity is born of boredom 49:42 The 8C Commitment Framework Links Watch it on YouTube: https://youtu.be/vhShZwzwQsI  Full episode show notes: https://outliyr.com/259  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

    56 min

  2. 23 APR

    #258 The Hidden Decisions Controlling Your Life (And How to Release Them) | Will Steel

    What if the reason your wins never feel like enough isn't a motivation problem, but a decision you made at age 3 that you don't even remember? Executive coach and former RAF pilot Will Steel joins Nick Urban to unpack how unconscious childhood decisions become the invisible architecture of an adult life. Will trained in ontological coaching under Werner Erhard's lineage and now works with CEOs, Buddhist monks, imams, and aspiring heads of state. His core message: limiting beliefs aren't abstract thoughts you can affirm your way out of. They're precise decisions made in specific moments, and they keep generating evidence to prove themselves right until you get to the exact words you said to yourself. Meet our guest Will Steel is an executive coach, former RAF pilot, and author of Free to Lead. He helps leaders build authentic, high-performing teams by focusing on identity, purpose, and behavior. His work blends military discipline with deep ontological inquiry, and he won't coach anyone for less than 12 months because real identity work takes time. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Limiting beliefs form from silent decisions made in specific childhood moments, not from the events themselves Your behavior produces the exact evidence that proves your hidden decisions right "I am depressed" fuses you to a state, "I have depression" treats it like a stomach ache and releases identity Body symptoms often communicate unsaid words — sore throats, sprained ankles, and digestive issues can map to suppressed messages "Fly the airplane" is the RAF drill Will uses in boardrooms: wings level first, checklist second Subtraction beats addition when you're stuck, get the facts before adding more strategies Real coaching happens in the listening, not the prescribing Fitra is an Arabic word for true essence, the seed that grows into a perfect plant in any soil Episode highlights 00:53  Unidentified past decisions limit what's possible 02:13  How belief loops form and lock in 07:22  "You should have been a girl" — the 40-year story 12:44  What ontology actually is 18:08  "I am depressed" vs "I have depression" 22:00  Body symptoms as unspoken communication 33:04  Fly the airplane: the emergency drill for life 43:28  Why subtraction beats stacking skills 46:14  Coaching CEOs, monks, and imams 51:32  The scientist whose $600 rate hid an 11-year-old story 56:33  The art dealer and the $17 million question 1:05:15  What fitra means and why it matters   Links Watch it on YouTube: https://youtu.be/eaBLmzfqf1s  Full episode show notes: https://outliyr.com/258  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

    1hr 8min

  3. 16 APR

    #257 Personalized Nutrition, RNA vs DNA & The Future of Microbiome Testing | Momo Vuyisich @Viome

    RNA microbiome testing reveals what DNA gut tests fundamentally miss. Your gut bacteria have 3,000+ genes each — DNA tests see zero of their actual activity. Dr. Momchilo (Momo) Vuyisich, Co-founder & CSO of Viome and former Los Alamos National Laboratory scientist, explains why RNA-based metatranscriptomics is a quantum leap over DNA sequencing for understanding your microbiome and personalizing nutrition. Meet our guest Dr. Momo Vuyisich spent 12 years at Los Alamos National Laboratory developing RNA-based technology for digitizing human biology. He co-founded Viome in 2016 with Naveen Jain, and the platform has since tested 500,000+ customers across 100+ countries. His personal journey with NEU5GC autoimmune sensitivity drove his mission to replace opinion-based nutrition with data-driven, personalized recommendations. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways DNA microbiome tests show composition only — RNA tests reveal which of 3,000+ bacterial genes are actually active 16S rRNA sequencing cannot distinguish pathogenic bacteria from beneficial ones Akkermansia can protect or destroy your gut lining depending on fiber intake and gene expression Carnitine supplements may cause cardiovascular disease via the TMAO pathway in certain people Viome's biological aging clock shows keto and paleo dieters age faster on average No whole food is universally good or bad — personalization requires your own molecular data The gut microbiome stays stable for 5-6 months; test semi-annually Viome currently measures 25,000 of ~100,000 biochemical reactions powering the body Three randomized controlled trials validate Viome's personalized nutrition approach   Episode highlights 00:00 Introduction 02:44 Why RNA is the single best molecule to study 06:16 RNA instability — why it took 6 years to develop 08:02 Why 16S sequencing is nearly useless 11:02 Akkermansia's 3,000 genes: help or harm? 17:37 Microbiome as a dynamic self-adjusting ecosystem 23:20 NEU5GC sensitivity & mammalian food reactions 25:50 Food sensitivities (IgG) vs allergies (IgE) 29:55 Viome's 3-part approach: seal gut, reduce inflammation, personalize 41:07 Biological aging clock: keto & paleo age faster 49:13 Dry fasting crashed mitochondrial function score 52:07 Machine learning identifies metabolic bottlenecks 1:00:23 Viome measures 25% of human biology, 10% actionable   Links Watch it on YouTube: https://youtu.be/bB8Zj_9pIv8  Full episode show notes: https://outliyr.com/257  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

    1hr 7min

  4. 9 APR

    #256 Flow State & Deep Work: How to Eliminate Distractions & Do Your Best Work | Steven Puri @The Sukha Company

    Are you busy all day but never finishing the work that actually matters? What if the problem isn't discipline — it's that you've never learned how to enter a flow state on demand? Steven Puri joins Nick Urban to break down the science and practice of flow states. Steven shares the exact protocol he built after two decades in Hollywood and tech: how music at 60-90 BPM triggers focus, why rain sounds outperformed $100K of custom compositions, and the morning intention habit he calls the single highest-ROI practice for productivity. Meet our guest Steven Puri is the Founder and CEO of The Sukha Company, a flow state productivity platform helping knowledge workers find their focus and do their best work. Before building Sukha, Steven served as VP at 20th Century Fox running the Die Hard and Wolverine franchises, EVP at DreamWorks Pictures for Kurtzman-Orci Productions (Star Trek, Transformers), and produced CGI for 14 films including Independence Day. He sold his first tech company, Centropolis Effects, at age 28. Steven lives in Austin, TX. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Flow takes 15-23 minutes of uninterrupted focus to enter — short gaps between meetings don't count Music at 60-90 BPM, non-vocal, with long melodic stretches is the evidence-based sweet spot Rain sounds beat custom-composed focus music because they trigger unconscious memory associations Your physical workspace creates mental triggers — one location per type of deep work Before touching your phone each morning, name the ONE thing that moves your life forward Standard Pomodoro (25/5) often interrupts flow — try 50/10 cycles instead Social media platforms deploy casino game designers to maximize your time on app A father of two completed his PhD with just 60 focused minutes per weeknight Episode highlights 00:54 Steven's background: Hollywood, startups & flow state discovery 02:58 What is a flow state? Csikszentmihalyi's research explained 11:05 How "Sukha" got its name on a honeymoon in Bali 18:35 Music for flow: the 60-90 BPM sweet spot 22:32 Why rain sounds crushed $100K of custom music 29:54 Social media is engineered to steal your focus 35:27 The #1 morning habit for peak productivity 37:13 Default mode network: why great ideas come when you're not trying 42:17 Physical space = mental space (the $5 million villa story) 47:32 Time blocking & Pomodoro customization 52:05 How a dad finished his PhD in 60-minute flow sessions Links Watch it on YouTube: https://youtu.be/KhesUIwp0pI  Full episode show notes: http://outliyr.com/256  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

    1hr 3min

  5. 2 APR

    #255 Recover from Total System Failure in 90 Days: The Resurrection Protocol for Burnt-Out High Achievers | Acusio Bivona

    You don't have a motivation problem. You have a TRUST problem. And the fix is so embarrassingly simple, you'll laugh at it — but it works. Acusio Bivona lost his relationship, his business, his friends, and nearly his mind... all in 5 months. What he built from the wreckage? A 90-day protocol that's helping founders go from total system failure to operating at a level they didn't know existed Meet our guest Acusio Bivona is a Human Performance Architect and founder of The Resurrection Protocol. After 10 years as a personal trainer in Los Angeles, he experienced 5 catastrophic life events in 5 months and used the rebuilding process to design a coaching methodology for high-achieving men. His approach fuses spiritual philosophy with physiological interventions to reverse burnout and restore command-level energy. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways System failure is when health, career, relationships, and purpose break down simultaneously — and recognizing it early changes the recovery trajectory Unbreakable Promises are commitments so small you laugh at them, yet your brain registers the win regardless of size Self-trust works like a bank account: $1 deposits (kept micro-promises) compound over time into genuine confidence Cold Resonance removes friction instead of adding force — producing more output with zero waste, like a superconductor The anterior midcingulate cortex literally grows at any age when you choose voluntary discomfort Protocol Zero stabilizes the first 48 hours after crisis using a 7-day digital blackout and immediate Unbreakable Promises Start with the body — fitness delivers the most tangible, visible results and builds momentum for everything else 20 minutes of daily silence with zero input is one of the highest-ROI habits for self-awareness Episode highlights 03:05 Reframing adversity as divine intervention 06:22 Kaizen philosophy: action breeds clarity 08:52 Unbreakable Promises explained 12:03 Hot Fusion vs Cold Resonance 15:02 Why fitness is the non-negotiable first pillar 20:21 Anterior midcingulate cortex: the "do hard muscle" 25:45 Attachment theory: anxious to earned security 28:53 What system failure actually looks like 32:56 You are your own primary care doctor 34:02 Solitude, silence, and meditation twice daily 37:37 Flow state and detaching from outcomes 43:34 Protocol Zero: first 48 hours after crisis 44:47 Digital blackout: 7 days off social media 47:07 Freedom app for enforcing the blackout Links Watch it on YouTube: https://youtu.be/fwwwR6ULiSc  Full episode show notes: http://outliyr.com/255  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

    55 min

  6. 26 MAR

    #254 The #1 Antioxidant You've Never Heard Of (SOD) & How to Boost It | François Vix @GliSODin

    Ever wonder why you spend hundreds on antioxidant supplements but still feel run down? What if the most powerful antioxidant isn't in your supplement cabinet — but already inside your body? François Vix, CEO of GliSODin with 40+ published clinical studies across 50+ countries, reveals why superoxide dismutase (SOD) neutralizes up to 1 billion free radicals per molecule while vitamin C handles just one. He breaks down the oxygen paradox driving "inflammaging," how mad cow disease nearly erased SOD from modern medicine, and the gliadin coating breakthrough that finally made oral supplementation possible.. Meet our guest François Vix is the President & CEO of GliSODin and a 20+ year leader in health innovation. He held strategic roles at L'Oréal, Lancôme, Biotherm, and Neutrogena International before founding Laboratoires Isocell in 2001 after identifying a stable, bioavailable form of superoxide dismutase. Today, GliSODin is available in 50+ countries with 40+ clinical studies and over 300 million daily doses sold worldwide. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways One molecule of SOD neutralizes up to 1 billion free radicals, while one vitamin C molecule neutralizes just one SOD hasn't changed in 2.5 billion years of evolution — it was dubbed "the enzyme of life" when discovered in 1968 Primary antioxidants (SOD, catalase, glutathione) work 24/7 while secondary antioxidants like vitamins are quickly spent  Mad cow disease killed injectable SOD in the '90s, and the scientific community assumed oral SOD was impossible  GliSODin's patented gliadin coating protects SOD through stomach acid and sticks to the small intestine wall for optimal absorption Just 2 weeks of SOD pre-treatment protected white blood cell DNA from fragmentation during 3-bar hyperbaric oxygen exposure SOD doesn't just boost the immune system — it regulates it, downregulating hyperactive responses in autoimmune conditions like vitiligo SOD production naturally declines after age 40, making supplementation more relevant for midlife and beyond Episode highlights 01:18 What is superoxide dismutase and why it's called the enzyme of life  06:29 The oxygen paradox and how inflammaging accelerates aging 07:59 SOD vs vitamin C — the 1 billion to 1 ratio explained 11:53 Why synthetic vitamins fall short of enzymatic antioxidants 15:41 Mineral cofactors your body needs to produce SOD 18:23 Does supplementing SOD downregulate your natural production? 25:20 SOD and hyperbaric oxygen — the DNA protection study 31:03 How mad cow disease nearly erased SOD from medicine                                                     34:00 The gliadin coating breakthrough for oral delivery                                                                  42:15 Is GliSODin safe for people with gluten sensitivity?                                                                 46:27 Lifestyle factors that deplete your SOD levels                                                                       51:53 How SOD regulates autoimmune conditions like vitiligo Links Watch it on YouTube: https://youtu.be/MGdfyXEmoFw  Full episode show notes: http://outliyr.com/254  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

    56 min

  7. 19 MAR

    #253 The Toxic Five: Hidden Causes of Chronic Fatigue & Long COVID | Dr. Evan Hirsch @ EnergyMD Method

    Ever feel exhausted no matter what you try, or notice new symptoms you can't explain since 2020? Dr. Evan Hirsch reveals the Toxic Five framework, the hidden combination of heavy metals, chemicals, molds, infections, & nervous system dysfunction that are the real root causes of chronic fatigue, long COVID, & autoimmunity. Meet our guest  Dr. Evan Hirsch is a board-certified MD and the founder of EnergyMD, where he specializes in treating chronic fatigue syndrome and long COVID. He has spent over a decade helping thousands of patients identify and address the root causes of their low energy. Dr. Hirsch resolved his own chronic fatigue syndrome using the same Toxic Five framework he now teaches. His 4-step process uses 100% natural tinctures and supplements, increased one drop at a time, to systematically detoxify at a rate each individual can tolerate. He operates online as a health coach and hosts the EnergyMD Podcast. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways About 36% of everyone who has had COVID develops persistent symptoms, making it a trillion-dollar annual problem most people don't even realize they have The Toxic Five (heavy metals, chemicals, molds, infections, nervous system dysfunction) cause 80% of the deficiencies that functional medicine typically treats as primary problem Over 90% of chronic fatigue cases can be identified through patient history & symptoms alone, saving thousands in unnecessary lab work Illness operates on 3 levels: lifestyle fixes, replacing deficiencies (adrenals, mitochondria, thyroid), & full Toxic Five removal for stubborn cases Biofilms shelter infections & toxins in a toxic matrix. COVID disrupts these biofilms, releasing dormant infections like Bartonella & Babesia A free 4-step mindset practice (gratitude, vision, belief flipping, empowering questions) combined with vagal toning rewires the nervous system Peptides, stem cells, ozone, & other advanced biohacks work best after 6-12 months of Toxic Five treatment, not before Episode highlights 00:55 Why most people have long COVID and don't even know it 03:10 The Toxic Five that are secretly draining your energy 04:19 How your pet could be making you sick & the symptoms to watch for 07:47 The 3 levels of illness and what to do at each one 13:59 The one-drop method that prevents detox disasters 30:01 A free daily practice that rewires your nervous system 34:06 Why peptides, stem cells, and biohacks keep failing you Links Watch it on YouTube: https://youtu.be/Jmmu-U4wmyg  Full episode show notes: http://outliyr.com/253  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

    51 min

  8. 12 MAR

    #252 Is Mitochondrial Dysfunction Driving Your Fatigue & Anxiety? | Dr. Scott Sher @ Troscriptions

    Ever feel tired & anxious even when your labs look “normal”? Dr. Scott Sher explains how mitochondrial dysfunction & metabolomics reveal what’s really happening at the cellular level & why optimizing your mitochondria changes energy, focus, & resilience. Meet our guest Dr. Scott Sherr is an integrative hyperbaric medicine specialist and co-founder of Troscriptions, the company behind the first commercial pharmaceutical-grade methylene blue product. He provides worldwide hyperbaric consultation, education, and advocacy. With nearly 6 years of clinical experience using methylene blue troches, he has developed protocols bridging mitochondrial dysfunction and nervous system recalibration. Dr. Sherr also co-founded Health Optimization Medicine and Practice (HOMe/HOPe), a nonprofit training clinicians in a 7-module framework for cellular health optimization. He is the founder of OneBase Health, developing next-generation sensor and app technology for health monitoring. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Your body operates as a holobiont—an ecosystem of human cells & microbes. True optimization requires influencing the entire internal network Data driven personalization beats influencer hype. Use targeted labs to build & adjust your own supplement stack over time Every organ system depends on cellular function. Optimize cells first before pursuing advanced protocols Metabolomics provides real time snapshots of unique biochemistry, guiding interventions based on actual needs Aim for optimal young adult biomarker ranges instead of settling for average aging norms Mitochondrial capacity drives cognition, recovery, & disease resistance. Most chronic issues trace back to energy dysfunction Chronic sympathetic activation locks the body in survival mode, draining cellular reserves & accelerating breakdown Short term mitochondrial support & stress downregulation create space for sustainable long term lifestyle upgrades Balanced excitatory & inhibitory neurotransmitters like GABA & glutamate support mood stability, anxiety regulation, & recovery Deep parasympathetic recovery unlocks greater cognitive & athletic return than constant stimulation or overwork Episode highlights 01:01 Holobiont concept: Why Dr. Sherr reframes biohacking as “biont hacking” 06:01 Sympathetic spiral of doom: How chronic fight-or-flight drains mitochondria 14:04 HRV as a nervous system barometer 21:25 Mitochondria beyond the textbook 41:00 Five root causes of mitochondrial dysfunction 48:50 Methylene blue as a mitochondrial bridge 50:58 GABA-glutamate imbalance in brain signaling 53:26 Obligatory pairs for GABA support 01:07:37 The parasympathetic edge for performance & recovery Links Watch it on YouTube: https://youtu.be/SImTojIu2aY  Full episode show notes: outliyr.com/252 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

    1hr 11min
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About

High Performance Longevity is the show for folks dedicated to maximizing their overall quality of life. I am your host Nick Urban and I’m bringing you the best minds handpicked from cognitive enhancement, BioHarmonization (biohacking 3.0), fitness, ancestral health, herbal medicine, spirituality, personal development, longevity, supplementation, and meditation. Each episode deconstructs their world-class work into tangible steps for you to look, feel, and perform your best. We’ll leave no stone unturned whether modern topics like peptides and nootropics, or ancient systems like Ayurveda and Traditional Chinese Medicine. You’ll learn how to re-sculpt your body, boost energy levels, improve athletic performance, and gain mental clarity. Nick Urban is a certified Chek Practitioner, biohacker, performance coach, and has spent a decade studying high performance. Health nut or not, HPL will fill your toolbox with products, tactics, knowledge, and resources needed to live at your maximum potential. Previously, this show was called Mind Body Peak Performance.

Information

  • Creator
    Nick Urban | Longevity, Biohacking, & Performance
  • Years Active
    2021 - 2026
  • Episodes
    262
  • Rating
    Explicit
  • Copyright
    © Outliyr LLC
  • Show Website
    High Performance Longevity

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