Epilepsy Sparks Insights

Torie Robinson
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Sparking interest and understanding in the epilepsies whilst bridging the communication gap between epilepsy patients, clinicians, scientists, geneticists – and the world. Hosted by Torie Robinson. **NOT FOR CLINICAL OR PATIENT DECISION-MAKING* Visit www.torierobinson.com & www.epilepsysparks.com.

  1. Just a Few Brain Cells Can Cause Epilepsy: Mosaicism - Dr. Stéphanie Baulac

    1 hr ago

    Just a Few Brain Cells Can Cause Epilepsy: Mosaicism - Dr. Stéphanie Baulac

    Most people think every cell in their body contains exactly the same DNA. It turns out that's not always true. Epilepsy genetics researcher Dr. Stéphanie Baulac explains mosaicism, how tiny genetic mutations can exist in just a small number of brain cells, and why they can cause a type of epilepsy called focal cortical dysplasia (FCD). These discoveries are transforming our understanding of epilepsy and could pave the way for highly targeted treatments in the future. Chapters 📖00:00 Trailer & intro00:55 Meet Dr. Stéphanie Baulac01:12 What is focal cortical dysplasia?02:33 Are these genetic mutations inherited?04:17 How can so few cells cause seizures?07:12 What is mosaicism?09:26 What does this mean for families?10:03 What is precision medicine?10:04 Can treatments target only the affected brain cells?12:49 Why were these mutations only discovered recently?14:23 How are these mutations detected?15:09 Closing thoughts & thanks 🔗 Episode page and transcript epilepsysparks.com/epilepsy-sparks-insights/fcd-mosaicism-somatic 🌐 More about Stéphanie epilepsysparks.com/guests/stephanie-baulac 🌐 More Epilepsy Sparks Insights epilepsysparks.com/epilepsy-sparks-insights 🎥 Watch on YouTube youtube.com/@EpilepsySparksInsights 🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary epilepsysparks.com/glossary 📲 Join us on social media!〰️ LinkedIn epilepsy-sparks〰️ Instagram epilepsysparks〰️ Facebook epilepsysparks〰️ TikTok epilepsysparks〰️ Bluesky epilepsysparks​

    16 min
  2. Is A Blood Brain Barrier Leak Causing Seizures? - Dr. Colin Doherty

    2 Jul

    Is A Blood Brain Barrier Leak Causing Seizures? - Dr. Colin Doherty

    Could inflammation and the blood-brain barrier help explain why some seizures remain uncontrolled? Prof. Colin Doherty discusses emerging research into immune activity in epilepsy, how steroids may temporarily improve seizure control, and why future immunotherapies could help some people whose seizures do not respond to current treatments. Chapters 📖00:00 Trailer & intro00:31 Precision therapy for autoimmune diseases01:27 Hypothesis: could steroids prevent seizures through mending the leakage of the Blood Brain Barrier? 03:53 Neurologists and researchers need to think about autoimmune04:57 Blood Brain Barrier, steroids and genetics - current study07:01 History: why haven’t we done this research already?08:13 Immunologists: work with us!09:48 Comparison: cancer and immunology12:08 Clinicians and scientists: work with us!13:51 People with an epilepsy and carers: work with us!15:27 Closing thoughts & thanks 🔗 Episode page and transcript epilepsy-sparks-insights/autoimmune-therapy-blood-brain-barrier 🌐 More about Colin epilepsysparks.com/guests/colin-doherty 🌐 More Epilepsy Sparks Insights epilepsysparks.com/epilepsy-sparks-insights 🎥 Watch on YouTube youtube.com/@EpilepsySparksInsights 🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary epilepsysparks.com/glossary 📲 Join us on social media!〰️ LinkedIn epilepsy-sparks〰️ Instagram epilepsysparks〰️ Facebook epilepsysparks〰️ TikTok epilepsysparks〰️ Bluesky epilepsysparks​

    16 min
  3. Could Immunotherapy Could Control Seizures? - Prof. Colin Doherty

    25 Jun

    Could Immunotherapy Could Control Seizures? - Prof. Colin Doherty

    Could the immune system play a bigger role in epilepsy than many of us realise? Prof. Colin Doherty explains how autoimmune epilepsies challenged the traditional view of epilepsy as purely an electrical disorder. He also discusses antibody-negative autoimmune epilepsy, early immunotherapy studies, and why some people with highly refractory epilepsy may respond to steroid treatment. Chapters 📖00:00 Trailer & intro00:44 Not just an “electrical disorder”02:19 30% still don’t have seizure control03:06 Epilepsy surgery04:54 Immunotherapy for epilepsy06:28 Immunotherapy cases10:20 Needing an immunotherapy program12:10 Steroids and profit13:16 Impacts of steroids - safety14:55 Closing thoughts & thanks 🔗 Episode page and transcript epilepsy-sparks-insights/autoimmune-therapy 🌐 More about Colin epilepsysparks.com/guests/colin-doherty Episode mentioned:🌐 Neurologist Diagnosed With Epilepsy - You'll Love His Positivity - Dr Jim Morrow 🌐 More Epilepsy Sparks Insights epilepsysparks.com/epilepsy-sparks-insights 🎥 Watch on YouTube youtube.com/@EpilepsySparksInsights 🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary epilepsysparks.com/glossary 📲 Join us on social media!〰️ LinkedIn epilepsy-sparks〰️ Instagram epilepsysparks〰️ Facebook epilepsysparks〰️ TikTok epilepsysparks〰️ Bluesky epilepsysparks​

    16 min
  4. Can Ketogenic Therapy Help More Than Seizures? - Dr. Manny Bagary

    18 Jun

    Can Ketogenic Therapy Help More Than Seizures? - Dr. Manny Bagary

    Could medical ketogenic therapy improve more than seizures?! Like anxiety and depression? Dr. Manny Bagary shares how clinciains assess whether ketogenic therapy is working, including its potential effects on anxiety, mood, cognition and quality of life. He also talks about common misconceptions, cholesterol worries, potential pregnancies, and why so many adults with epilepsy still struggle to access specialist ketogenic therapy services. This is episode 2 of 2 with Manny. This episode is sponsored by Kanso, a brand by Dr. Schär, who had no influence over the editorial content or discussion. Learn more about Kanso here: kanso.com/en Chapters 📖00:00 Trailer & intro01:50 When do you know if the ketogenic diet isn’t working?03:40 Impact on quality of life - anxiety, depression, cognition05:45 Misinformation regarding medical ketogenic therapy08:44 Feeling full09:55 When the diet isn’t safe12:20 Secondary benefits of keto diet14:08 Bipolar disorder and the diet14:53 Cholesterol - the elephant in the room18:28 Lack of adult ketogenic diet treatment centres23:19 Closing thoughts & thanks 🔗 Episode page and transcript epilepsysparks.com/epilepsy-sparks-insights/efficacy-safety-mood-availability 🌐 More about Manny epilepsysparks.com/guests/manny-bagary 🌐 More Epilepsy Sparks Insights epilepsysparks.com/epilepsy-sparks-insights 🎥 Watch on YouTube youtube.com/@EpilepsySparksInsights 🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary epilepsysparks.com/glossary 📲 Join us on social media!〰️ LinkedIn epilepsy-sparks〰️ Instagram epilepsysparks〰️ Facebook epilepsysparks〰️ TikTok epilepsysparks〰️ Bluesky epilepsysparks

    24 min
  5. Ketones Are Changing Your Brain - Epilepsy! - Dr. Manny Bagary

    15 Jun

    Ketones Are Changing Your Brain - Epilepsy! - Dr. Manny Bagary

    Medical Ketogenic Therapy can reduce seizures in some people - but how does it actually work?! Dr. Manny Bagary explains the nitty gritty of ketones, interactions, how they might affect brain excitability, what’s going on with neurotransmitters, mitochondria, inflammation, and even the gut microbiome! He also shares how ketogenic therapy might improve cognition, when a person should be offered it, and how it can help with status epilepticus! This is episode 1 of 2 with Manny. This episode is sponsored by Kanso, a brand by Dr. Schär, who had no influence over the editorial content or discussion. Learn more about Kanso here: kanso.com/en Chapters 📖00:00 Trailer & intro01:29 Meet Manny02:03 What are ketogenesis, ketosis, ketone bodies, etc.?04:17 What makes ketosis stop seizures (in some people)?08:00 Impacts on anxiety, depression, cognition and more09:42 Different types of ketogenic diet13:17 Ketogenic therapy for status epilepticus16:31 Ketogenic diet in adults19:10 Forms of treatment - when does the ketogenic diet come in? 22:28 Closing thoughts & thanks 🔗 Episode page and transcript epilepsysparks.com/epilepsy-sparks-insights/ketones-anxiety-depression-status-epilepticus 🌐 More about Manny epilepsysparks.com/guests/manny-bagary 🌐 More Epilepsy Sparks Insights epilepsysparks.com/epilepsy-sparks-insights 🎥 Watch on YouTube youtube.com/@EpilepsySparksInsights 🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary epilepsysparks.com/glossary 📲 Join us on social media!〰️ LinkedIn epilepsy-sparks〰️ Instagram epilepsysparks〰️ Facebook epilepsysparks〰️ TikTok epilepsysparks〰️ Bluesky epilepsysparks

    24 min
  6. The Epilepsy Diet Most People Get Wrong - Keto - Dr. Neha Kaul

    4 Jun

    The Epilepsy Diet Most People Get Wrong - Keto - Dr. Neha Kaul

    Medical ketogenic therapy has more than 100 years of evidence behind it - so why is it still often treated as a last resort?! Ketogenic dietitian Neha Kaul explains how success can go beyond potential seizure reduction, and how the diet may affect cognition, mood and overall quality of life. Neha also covers common misconceptions, safety concerns, and what it really takes to make the diet work in everyday life. This episode is sponsored by Kanso, a brand by Dr. Schär and had no influence over the editorial content or discussion. Learn more about Kanso here: kanso.com/en Chapters 📖00:00 Trailer & intro01:38 Why is the ketogenic diet not widely used?04:02 Research: supporting people trying the ketogenic diet04:48 What is ketosis?07:15 Other benefits of ketogenic diet08:58 Ketogenic diet for adults - research09:34 Who’s suitable for the diet?12:37 Confusion re the diet14:01 Who responds well to the diet?15:32 Mistakes with the diet are normal18:38 Safety concerns - cholesterol and nutrient deficiencies?22:37 How much fat, protein, and carbs should be consumed? 23:39 Interactions with medications25:32 Benefits vs trade-offs27:47 Understanding personal barriers, support needed29:36 Neurologists & those with an epilepsy: know this32:34 Closing thoughts & thanks 🔗 Episode page and transcript epilepsysparks.com/epilepsy-sparks-insights/ketogenic-diet-support 📖 Jasper's Basics of Epilepsies: academic.oup.com/book/57972/chapter/476213922 🌐 More about Neha epilepsysparks.com/guests/neha-kaul 🌐 More Epilepsy Sparks Insights epilepsysparks.com/epilepsy-sparks-insights 🎥 Watch on YouTube youtube.com/@EpilepsySparksInsights 🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary epilepsysparks.com/glossary Click here to view the episode transcript. 📲 Join us on social media!〰️ LinkedIn epilepsy-sparks〰️ Instagram epilepsysparks〰️ Facebook epilepsysparks〰️ TikTok epilepsysparks〰️ Bluesky epilepsysparks

    34 min
  7. Focal Epilepsy Onset Later In Life - With Origins In Childhood - Dr. Jacob Pellinen

    28 May

    Focal Epilepsy Onset Later In Life - With Origins In Childhood - Dr. Jacob Pellinen

    Signs of focal epilepsy before the seizures start: hear all about it from neurologist and epileptologist Dr. Jacob Pellinen, who shares with us his research and results proving that people can experience things like depression or learning difficulties at school or work before seizure onset. Chapters 📖00:00 Trailer & intro00:44 Meet Jacob02:34 Epilepsy is more than seizures02:54 Later epilepsy diagnosis & The Human Epilepsy Project 03:05 “Later onset focal epilepsy with roots in childhood: Evidence from early learning difficulty and brain volumes in the Human Epilepsy Project” paper 07:29 Anticipating seizure onset08:30 Improving recognition of seizure symptoms09:02 Seizing for years before diagnosis10:33 Learning difficulties not Intellectual Disability13:18 Closing thoughts & thanks 🔗 Episode page and transcript epilepsysparks.com/epilepsy-sparks-insights/unrecognised-focal-onset-childhood 🌐 More about Jacob epilepsysparks.com/guests/jacob-pellinen 🌐 More Epilepsy Sparks Insights epilepsysparks.com/epilepsy-sparks-insights 🎥 Watch on YouTube youtube.com/@EpilepsySparksInsights 🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary epilepsysparks.com/glossary 📲 Join us on social media!〰️ LinkedIn epilepsy-sparks〰️ Instagram epilepsysparks〰️ Facebook epilepsysparks〰️ TikTok epilepsysparks〰️ Bluesky epilepsysparks

    14 min
  8. Can You Improve Memory In Epilepsy? - Dr. Laurie Miller

    21 May

    Can You Improve Memory In Epilepsy? - Dr. Laurie Miller

    Memory problems are one of the most common and frustrating symptoms experienced by people with an epilepsy - but what actually causes them? And how can we "treat" them? Dr. Laurie Miller explains how different types of memory work, why memory difficulties are often linked to the underlying brain pathology rather than just seizures, and what evidence-based strategies and techniquest may help improve everyday functioning.   👕 Join the Epilepsy Sparks community with our merch 👇🏻 https://epilepsy-sparks.creator-spring.com   🌐 More Epilepsy Sparks Insights 👇🏻 https://www.epilepsysparks.com/epilepsy-sparks-insights   🎧 Listen to the Epilepsy Sparks Insights podcast on Apple, Spotify, or your favourite provider!   🔤 Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary   📲 Join us on social media! - LinkedIn https://www.linkedin.com/company/epilepsy-sparks - Instagram https://www.instagram.com/epilepsysparks - Facebook https://www.facebook.com/epilepsysparks - TikTok https://www.tiktok.com/@epilepsysparks - Bluesky https://bsky.app/profile/epilepsysparks.bsky.social

    18 min
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About

Sparking interest and understanding in the epilepsies whilst bridging the communication gap between epilepsy patients, clinicians, scientists, geneticists – and the world. Hosted by Torie Robinson. **NOT FOR CLINICAL OR PATIENT DECISION-MAKING* Visit www.torierobinson.com & www.epilepsysparks.com.

Information

  • Creator
    Torie Robinson
  • Years Active
    2021 - 2026
  • Episodes
    275
  • Rating
    Clean
  • Copyright
    © 2026 Epilepsy Sparks Insights
  • Show Website
    Epilepsy Sparks Insights

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