Longevity Optimization with Kayla Barnes-Lentz

Kayla Barnes-Lentz

Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.

  1. 12 HR AGO

    Dr. Bérénice Benayoun, PhD: Why Your Ovaries Age (And the Gut Connection)

    Bérénice Benayoun, PhD, explains why ovarian aging may be one of the earliest and most important drivers of female aging, influencing the brain, immune system, metabolism, and long-term disease risk far beyond reproduction. She breaks down what we actually know so far, including DNA damage, mitochondrial dysfunction, fibrosis, hormonal signaling, and why the ovary appears to age faster than other tissues. We also get into one of the most surprising findings in the field right now: a brand new study from her lab found that post-reproductive gut microbiota unexpectedly improved ovarian reserve and lowered inflammatory signals in young mice, raising a completely new set of questions about the gut-ovary connection and what may eventually be possible for ovarian health. Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/female-longevity-community In this conversation: -Why the ovary may be the fastest aging organ in the female body -Why menopause is a healthspan issue, not just a fertility issue -DNA damage, mitochondria, fibrosis, and the hallmarks of ovarian aging -The new microbiome finding that surprised even the researchers -Why later menopause predicts longer and healthier life -Rapamycin, hormone therapy, and what may actually help If you’re already paying attention to food, sleep, and overall health, cleaning products are another place where exposure adds up quickly. Branch Basics is a simple way to clean your home with fewer unnecessary ingredients and less clutter under the sink. Check them out: https://branchbasics.com/KAYLA15For 15% off use code: KAYLA15 Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054 Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227 Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Learn more about Bérénice Benayoun:LinkedIn: https://www.linkedin.com/in/b%C3%A9r%C3%A9nice-benayoun-a374a74b/en/Website: https://gero.usc.edu/labs/benayounlab/Her New Study (Estropausal gut microbiota transplant improves measures of ovarian function in adult mice): https://pubmed.ncbi.nlm.nih.gov/41776310/

    1hr 33min

  2. 2 APR

    Dr. Deb Rivera, PhD: The Missing Link Between Stress, Aging, and Resilience

    Most people can feel when stress is affecting them. Far fewer know whether their body is adapting well or quietly being pushed toward dysfunction. In this episode, Dr. Deb Rivera, PhD in neuroengineering, explains the hidden biological system that helps determine how well your body handles stress. Her research focuses on redox balance and the glutathione ratio, a biomarker that may reveal whether your body is adapting to stress or slowly moving toward dysfunction. Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/checkout/become-a-member In This Conversation -How to tell whether stress is helping or harming the body-The glutathione ratio and what it reveals about resilience-The role of redox balance in aging and metabolic health-Why recovery capacity determines how you respond to stress-How lifestyle factors influence mitochondrial and cellular health-Microplastics, environmental stressors, and biological resilience-Practical ways to support your body’s stress-adaptation system Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ Spotify:https://open.spotify.com/show/4OLWWn22... Apple: https://podcasts.apple.com/us/podcast... Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Learn more about Dr. Deb Rivera: LinkedIn: https://www.linkedin.com/in/journeymetrics/ Website: https://journeymetrics.io/

    1hr 33min

  3. 26 MAR

    Dr. Eboni Cornish, MD: Brain Longevity, Neuroinflammation, and What Quietly Damages the Brain

    Brain health problems rarely begin where most people look. Memory issues, low mood, poor focus, anxiety, and even early cognitive decline can be driven by hidden inflammation and root-cause imbalances long before they show up the way most people expect. In this episode, Dr. Eboni Cornish explains how chronic infections, mold, toxins, hormones, gut dysfunction, and oral or nasal microbial imbalances can all affect the brain, and why “mental health” often needs to be approached as brain health first. She also shares how tools like brain imaging, inflammation markers, and functional testing can uncover patterns that are often missed in standard workups, while outlining the core foundations that support long-term brain health, including sleep, exercise, omega-3s, vitamin D, hormone balance, gut health, and detox capacity. Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/checkout/become-a-member In This Conversation: - Why brain symptoms can start outside the brain - How neuroinflammation can affect mood, focus, and memory - Mold, Lyme, Epstein -Barr, and other overlooked brain disruptors - Why gut, oral, and nasal health matter for cognition - The tests and markers that can reveal early brain stress - The foundations that support brain longevity Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ YouTube: www.youtube.com/@KaylaBarnesLentz Spotify:https://open.spotify.com/show/4OLWWn22... Apple: https://podcasts.apple.com/us/podcast... Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Learn more about Eboni Cornish: Instagram: https://www.instagram.com/dr.ebonicornish/ TikTok: https://www.tiktok.com/@drebonicornish Website: https://www.drebonicornish.com/ Amen Clinics: https://www.amenclinics.com/team/eboni-cornish-md/

    1hr 39min

  4. 19 MAR

    Jessie Inchauspé Glucose Goddess on CGMs, Crashes & The Biggest Glucose Mistakes

    Blood sugar stability may be one of the most important levers for long term health, yet most people never look at it.In this episode, I am joined by Jessie Inchauspé, widely known as the Glucose Goddess, to examine what glucose spikes are actually doing inside the body and why they matter even if you are not diabetic.We unpack how glucose spikes can influence your mood, focus, cravings, and energy levels, why blood sugar stability matters even if you are not diabetic, and how seeing your own patterns can completely change the way you approach food.Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/checkout/become-a-memberWe also cover:- The biggest glucose mistakes most people make- Why “healthy” breakfasts often lead to energy crashes- How dinner timing impacts deep sleep- The connection between glucose spikes and skin aging through glycation- Simple strategies like food order and walking after meals- How a mother’s glucose levels can influence her baby’s long term metabolic riskUnderstanding your glucose patterns gives you leverage, and small, strategic shifts can compound into measurable long term health improvements. Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ Spotify:https://open.spotify.com/show/4OLWWn22... Apple: https://podcasts.apple.com/us/podcast... Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Connect with Glucose Goddess:Website: https://www.glucosegoddess.com/YouTube: https://www.youtube.com/@GlucoseRevolutionInstagram: https://www.instagram.com/glucosegoddess/TikTok: https://www.tiktok.com/@glucosegoddess_Pre-order her new book: https://www.glucosegoddess.com/pages/9-months-that-count-forever

    51 min

  5. 12 MAR

    Dr. Deanna Minich, PhD: How Women Should Structure Macros in Their Meals

    Women are told to fast, cut carbs, eat high protein, avoid seed oils, and track macros, but most of that advice ignores female physiology. In this episode, I’m joined by Dr. Deanna Minich, PhD, certified functional medicine practitioner and nutrition scientist. We walk through the Female Longevity Nutrition Protocol she created, including circadian timing, macro ranges by life stage, and how to stop getting whiplash from internet nutrition trends. Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/checkout/become-a-member In This Conversation: The “breakfast myth” and why your ovaries won’t shrink Eating earlier in the day, circadian timing, and appetite regulation Macro ranges by life stage and why Deanna uses ranges, not rigid targets Perimenopause and postmenopause macro shifts Omega Index testing and why it matters Fiber, fats, seed oils, and what the research actually supports Micronutrient testing and how to personalize nutrition and supplements Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ Spotify:https://open.spotify.com/show/4OLWWn22...YouTube: www.youtube.com/@KaylaBarnesLentz Apple: https://podcasts.apple.com/us/podcast... Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Learn more about Dr. Deanna Minich: Instagram: https://www.instagram.com/deannaminich/ Website: https://deannaminich.com/ YouTube: www.youtube.com/@foodandspirit

    1hr 46min

  6. 5 MAR

    Dr. Susanna Søberg, PhD: The Science of Cold Plunges for Women

    Cold exposure is not a badge of toughness. It’s a stressor. And if you do it wrong, you can absolutely overdo it. In this episode, I’m joined by Dr. Susanna Søberg, PhD, scientist and educator specializing in metabolism, cold and heat exposure, and longevity. We break down what cold exposure is actually doing in the body, why brown fat matters for metabolic health, and how women should think about timing cold exposure around PMS, luteal phase, and menstruation. Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/checkout/become-a-member In This Conversation: -Why cold exposure works best when it’s short and strategic -Brown fat, insulin sensitivity, and why it doesn’t have to be “that cold”  -Cold vs heat for women, and why “better” depends on the outcome -PMS timing and when to pull back on stressors -Temperature, time, and the real dose-response of cold exposure -How to spot viral claims that sound exciting but aren’t science Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ Spotify:https://open.spotify.com/show/4OLWWn22... Apple: https://podcasts.apple.com/us/podcast... Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Learn more about Susanna Søberg, PhD: Instagram: https://www.instagram.com/susanna_soeberg Website: https://soeberginstitute.com/ Thermalist Women’s Retreat With Dr. Susanna Søberg: https://soeberginstitute.com/pages/thermalist%C2%AE-women-s-retreat

    1hr 21min

  7. 26 FEB

    Dr. Stephanie Riley Hahn: Pelvic Floor Optimization, Leaks, Sex, And Prolapse

    Pelvic floor problems are not a “just do more kegels” issue.For a lot of women, kegels are either not specific enough, or they make symptoms worse. In this episode, Dr. Stephanie Riley Hahn, pelvic floor physical therapist and founder of Longevity and Pilates, breaks down what pelvic floor dysfunction actually is, how to tell weakness from tightness, and why pressure management and breathing mechanics often matter more than squeezing harder. Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/checkout/become-a-member In this conversation: Why pelvic floor tightness can drive pain, irritation and symptoms The difference between weakness and tension, and how to tell How breathing and pressure management change everything What downtraining involves, and what tends to backfire Prolapse support options, and when to seek help Overactive bladder and constipation patterns that keep symptoms alive Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ Spotify:https://open.spotify.com/show/4OLWWn22... Apple: https://podcasts.apple.com/us/podcast... YouTube: www.youtube.com/@KaylaBarnesLentz Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Learn more about StephanieInstagram: https://www.instagram.com/longevityptpilates/Website: https://www.longevityptandpilates.com/ Shownotes:Pelvic floor PT locator: https://www.aptapelvichealth.org/ptlocator

    1hr 36min

  8. 19 FEB

    Dr. Aimie Apigian, MD: The Biology of Trauma + Nervous System Safety

    Longevity isn’t just workouts, supplements, and recovery tools, it starts with nervous system health.  In this episode, Dr. Aimie Apigian explains what trauma actually is (not a label, but a measurable physiological response), how the body shifts from stress into overwhelm, and why “pushing through” often turns into years of avoidance, numbing, and hidden internal strain. She breaks down the biology behind the trauma response, including the role of adrenaline, cortisol timing, and how mitochondrial capacity influences resilience. You’ll also learn her practical, body-based approach to creating “safe enough” in real time, plus the three phases of healing: safety, support, and expansion, so you don’t stay stuck avoiding triggers forever. In this conversation: Stress vs trauma response (and what changes physiologically)Why adrenaline drives the response and cortisol arrives laterHow the body stores trauma as patterns, not just memoriesThe 3 nervous system states and the thoughts they generateA simple somatic exercise to build safety in the bodyWhy devices/meds can be bridges, not the destinationUsing biomarkers + wearables without fooling yourselfWhy modern media can create vicarious traumaJoin the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/checkout/become-a-member Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ YouTube: www.youtube.com/@KaylaBarnesLentz Spotify:https://open.spotify.com/show/4OLWWn22... Apple: https://podcasts.apple.com/us/podcast... Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Learn more about Dr. Aimie Apigian, MD: Instagram: https://www.instagram.com/draimie/ YouTube: https://www.youtube.com/c/DrAimieApigian Website: https://www.biologyoftrauma.com/ Order her Book “The Biology of Trauma”: https://www.biologyoftrauma.com/book

    1hr 55min
See All (151)

About

Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.

Information

You Might Also Like