Nucleate Podcast Nucleate

In this episode of the Nucleate Podcast, we are joined by Ananya Zutshi and Ricky Barrett, founders of Guardian Bio, a Boston-based biotech company (and Nucleate Alumni). Their platform focuses on engineering dendritic cells to target solid tumors. We delve into the ups and downs of their entrepreneurial journey, the unique dynamic between co-founders, and their advice for communicating complex science topics.

In this episode of the Nucleate Podcast, we are joined by Ananya Zutshi and Ricky Barrett, founders of Guardian Bio, a Boston-based biotech company (and Nucleate Alumni). Their platform focuses on engineering dendritic cells to target solid tumors. We delve into the ups and downs of their entrepreneurial journey, the unique dynamic between co-founders, and their advice for communicating complex science topics.

Check out Episode 8 of the Nucleate Podcast. We were honored to have Sean McClain, the founder and CEO of AbSci speak about generative AI for developing novel therapies. The potential to accelerate development of therapies for patients is astronomical.

This episode is a conversation with Prof Bobby Gaspar, the CEO of Orchard Therapeutics, a clinical stage biotech company developing gene therapies for severe diseases. Signal host Ursule Demael speaks to Prof Bobby Gaspar, who holds an MD/PhD and is an honorary professor of Paediatrics and Immunology at Great Ormond Street Hospital in London (United Kingdom). He has decades of expertise across academic research and biotech developing haematopoietic stem cell therapies for patients with immune deficiencies and metabolic disorders. Orchard’s lead therapy Libmedly is approved for the metabolic disorder MLD in Europe.

Orchard Therapeutics Website: https://www.orchard-tx.com/about/our-story/

On this episode of the podcast, Signal hosts Michael Retchin and Ursule Demael interview Prof. Lee Cronin from Chemify. Lee Cronin is a Professor at the University of Glasgow, where he leads a research group focused on digital chemistry, automating chemical synthesis and origin of life. Lee Cronin is also the co-founder and CEO of Chemify, a startup advancing digitization and robotics for chemistry.

In this episode, we discuss the idea of building a search engine for chemistry, the founding story of Chemify, and important differences between running an academic lab and a successful Series A stage startup. Lee Cronin shares how unique aspects of his personality and persistence were critical to build Chemify.

Lee Cronin is an outspoken scientist, who is active on Twitter and has appeared on the Lex Fridman podcast, making for a fascinating and engaging episode!

In this episode, Nucleate Signal hosts Eric Dai and Jingyi Liu interview Dr. Trevor Martin from Mammoth Bio. They discuss Trevor's career inspirations, pivot from academia to biotech entrepreneur, the mission of Mammoth Bio, as well as lessons learned as CEO. Mammoth Biosciences is focused on discovering novel CRISPR systems that enable new possibilities for expanding biology.