When Science Finds a Way

Wellcome

Science is always adding to our knowledge of health, but how do ideas become breakthroughs, and how can those breakthroughs bring about a better world? Could mosquitos help prevent disease? Will AI tools transform mental healthcare? How is a once-ignored drug now being used to save lives? And what can science do to keep us healthy as we age? Join botanist-turned-Hollywood actor Alisha Wainwright as she meets the scientists, innovators, and communities working together to solve our biggest health challenges. **** We want to hear from you! Our podcast is shaped by the people who listen to it. Please tell us a bit about your experience by filling out our short listener survey: https://www.surveymonkey.com/r/SX6X8X3 **** Brought to you by Wellcome, an independent global foundation that supports science to solve the urgent health challenges facing everyone. Please visit wellcome.org for more information.

  1. Is tackling super pollutants an emergency brake for climate change?

    5 days ago

    Is tackling super pollutants an emergency brake for climate change?

    We may think of carbon dioxide as the main culprit in climate change, but could tackling "super pollutants" provide an emergency brake for global warming?  Dr Tom Grylls tells Alisha Wainwright how we already have the tools to reduce these gases and particles, and Bidya Banmali Pradhan describes a successful effort to do just that by re-engineering brick kilns in Nepal.  But this isn't only a question of climate. Professor Zorana Andersen explains air pollution's impact on our bodies, and we hear how a holistic view of climate and health could help slow down global warming and save millions of lives.  *** Mentioned in this episode and further reading: What are super pollutants and how do they impact our health? - Wellcome (https://wellcome.org/insights/articles/what-are-super-pollutants-and-how-do-they-impact-our-health)  Why reducing super pollutants isn't just good for the climate – Clean Air Fund (https://www.cleanairfund.org/news-item/reducing-super-pollutants/)  Building cleaner brick kilns in Nepal - CCAC (https://www.ccacoalition.org/projects/building-cleaner-brick-kilns-nepal)

    40 min
  2. Is hope on the horizon for treating drug-resistant TB?

    27 May

    Is hope on the horizon for treating drug-resistant TB?

    Tuberculosis has been with us so long that traces appear in mummies. But today, the challenge is different: how do we respond to TB that's resistant to modern drugs?  Professor Salome Charalambous tells Alisha Wainwright about the challenges of treating the half-million people with drug-resistant TB, and Professor Nazir Ismail explains how it gets harder in countries where resources are scarce.  But there may be hope on the horizon. Salome gives a glimpse of the new tests and treatments already saving lives, and we hear from Enalkachew Fekadu, a drug-resistant TB survivor who now advocates for others with the disease.

    45 min
  3. How can we respond to extreme heat and its effect on mental health?​

    20 May

    How can we respond to extreme heat and its effect on mental health?​

    We know how extreme heat impacts us physically, but science is still uncovering its effects on mental health.  Professor Andrea Mechelli tells Alisha Wainwright what analysing millions of datapoints is teaching us, we hear from participants in his London-based research about their struggles with heat and mental health, and Mete Çoban, London's Deputy Mayor for Environment and Energy, talks about efforts to future-proof the city.    Looking beyond London, Dr Benedict Weobong explains why his research in Ghana and Zimbabwe shows that local context is crucial for dealing with heat-related mental health issues, and Alisha explores how reconnecting with nature - and each other - could also help us tackle the causes of rising heat.  *** Mentioned in this episode and further reading:  Prof. Andrea Mechelli's Substack on how nature and climate shape our mental health: https://andreamechelli.substack.com/ The effects of extreme heat events on mental health in vulnerable urban communities: towards evidence-based policy and practice (https://www.kcl.ac.uk/research/the-effects-of-extreme-heat-events-on-mental-health-in-vulnerable-urban-communities-towards-evidence-based-policy-and-practice)  Urban Mind – an app that measures your experience of urban & rural living in the moment (https://urbanmind.info/)   Heat Exposure, Sleep, Cognition and Mental Health - HEATSCAPE-Africa (https://www.yorku.ca/dighr/project/heatscape-africa/)

    46 min
  4. We're living longer, but are we living healthier?

    13 May

    We're living longer, but are we living healthier?

    In much of the world people are living longer, but how can we make sure those extra years are healthy? Professor Dame Linda Partridge tells Alisha Wainwright how our ever-growing knowledge of health and ageing could lead to more personalised medicine, and Professor Mika Kivimäki explains how new methods for measuring the "biological age" of our organs could be used to predict disease. We also hear from Shamita Sharmacharja, curator of the new Coming of Age Exhibition at London's Wellcome Collection, about how changing society could help us all age better.  *** Mentioned in this episode and further reading:  Hallmarks of ageing: an expanding universe (https://pubmed.ncbi.nlm.nih.gov/36599349/)  Biological organ ages predict disease risk decades in advance, Mika Kivimäki , UCL Faculty of Brain Sciences (https://www.ucl.ac.uk/news/2025/feb/biological-organ-ages-predict-disease-risk-decades-advance)  The Coming of Age Exhibition, Wellcome Collection, London. Open until November 2026 (https://wellcomecollection.org/exhibitions/the-coming-of-age)

    40 min
  5. Does the food we eat improve our mental health?

    6 May

    Does the food we eat improve our mental health?

    We know that the food we eat affects us physically, but how might our diets help or hinder mental health? Dr Wolfgang Marx tells Alisha Wainwright about his work to find a link between mental health and diet. We also hear from Dr Iain Campbell, who found that a famous diet helped his own bipolar symptoms, inspiring him to work on a new large-scale trial. And Dr Sheri Johnson explains why we should explore not just what we eat, but when.  *** Mentioned in this episode and further reading:  Food and mood centre, a multi-disciplinary research centre that aims to understand the complex ways in which what we eat influences our brain, mood, and mental health, Deakin University (https://foodandmoodcentre.com.au/)  Time-restricted eating as an adjunctive intervention for bipolar disorder – Wellcome funding award (https://wellcome.org/research-funding/funding-portfolio/funded-grants/time-restricted-eating-adjunctive-intervention)  Personal keto journey leads to career in research: Iain Campbell's story (https://www.metabolicmind.org/thinksmart/explore-strategies/iain-campbell/)

    42 min
  6. Why was a life saving drug overlooked for half a century?

    29 Apr

    Why was a life saving drug overlooked for half a century?

    Tranexamic acid (TXA) has enormous potential to prevent deaths from postpartum haemorrhage, but until very recently it's been overlooked. Professor Haleema Shakur Still tells Alisha Wainwright how she stumbled on TXA's untapped potential, and the drug's journey from being an undervalued discovery in post-war Japan to a groundbreaking treatment in modern-day Nigeria. Professor Nike Bellow and Dr Abiola Akiyode-Afolabi share their efforts to make TXA more accessible to communities, while Haleema explains how drug trials have revealed a hidden side to postpartum haemorrhage – one that could prevent cases before treatment is even needed.  **** Mentioned in this episode and further reading:  WOMAN trials: looking at the effect of the drug tranexamic acid (TXA) on bleeding, and the best ways to give it (https://thebloodtrials.org/womens-health-trials/)  The missing evidence: anaemia, postpartum bleeding and maternal death, Blood Trials, LSHTM (https://thebloodtrials.org/the-missing-evidence/)  A word of thanks to all the WOMAN Trial collaborators, Professor Ian Roberts, who co-led the WOMAN Trials alongside Haleema, trial teams in London, Nigeria, Pakistan, Tanzania and Zambia and the women and families who make this work possible.

    40 min
  7. What happens when fungi find their way into our brains?

    22 Apr

    What happens when fungi find their way into our brains?

    It might sound like something out of TV shows like The Last of Us, but brain-invading fungi are a real-world problem. Alisha Wainwright speaks to Drs. Rachael Dangarembizi and Rebecca Drummond, an immunologist and a neuroscientist collaborating across continents to tackle Cryptococcal Meningitis – the leading cause of fungal death worldwide. Dr Kyla Murphy also talks about the new tests and treatments saving lives from the disease, and Alisha shares the story of her own mother's brush with a dangerous fungal infection.  **** Mentioned in this episode and further reading:  Will climate change lead to more fungal infections? An explainer by Wellcome (wellcome.org/insights/articles/will-climate-change-lead-more-fungal-infections)  Wellcome Fungal Adaptation Call Awardees (wellcome.org/research-funding/funding-portfolio/funded-grants?f%5B0%5D=funding_scheme_grants_awarded%3ABiology%20of%20fungal%20adaptation  Global incidence and mortality of severe fungal disease, David W Denning, The Lancet Infectious Diseases (thelancet.com/journals/laninf/article/PIIS1473-3099(23)00692-8/fulltext)  The WHO fungal priority pathogens list as a gamechanger, Matthew C. Fisher & David W. Denning, Nature Reviews Microbiology (nature.com/articles/s41579-023-00861-x#citeas)  How fungi shape our world...and how the climate is shaping our fungi – The Naked Scientist Podcast in partnership with Wellcome (thenakedscientists.com/podcasts/naked-scientists-podcast/how-fungi-shape-our-world)  When Science Finds a Way is brought to you by Wellcome, an independent global foundation that supports science to solve the urgent health challenges facing everyone. For more information and podcast transcripts visit wellcome.org/podcast

    43 min
  8. AI and mental health: can we trust AI therapy?

    15 Apr

    AI and mental health: can we trust AI therapy?

    AI chatbots and apps are increasingly being used for mental health support. But could these new tools carry hidden risks?   In the second part of this special episode, Alisha Wainwright unpicks her own experiments with AI therapy, takes tips from Dr John Torous on staying safe when seeking help digitally, and hears about the risks of unregulated tools.    But there's hope with these tools too. Professor Miranda Wolpert reveals how AI could help scale mental health interventions in the globally and even inspire whole new forms of therapy.  **** Mentioned in this episode and further reading: AI and mental health: "it could help revolutionise treatments" - Miranda Wolpert, Director of Mental Health, Wellcome  (https://wellcome.org/insights/articles/ai-and-mental-health-help-revolutionise-treatments) Generating evidence for AI in health (EVAH) (https://wellcome.org/insights/articles/evah-new-initiative-generate-evidence-ai-health)   When Science Finds a Way is brought to you by Wellcome, an independent global foundation that supports science to solve the urgent health challenges facing everyone. For more information and podcast transcripts visit wellcome.org/podcast

    38 min
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About

Science is always adding to our knowledge of health, but how do ideas become breakthroughs, and how can those breakthroughs bring about a better world? Could mosquitos help prevent disease? Will AI tools transform mental healthcare? How is a once-ignored drug now being used to save lives? And what can science do to keep us healthy as we age? Join botanist-turned-Hollywood actor Alisha Wainwright as she meets the scientists, innovators, and communities working together to solve our biggest health challenges. **** We want to hear from you! Our podcast is shaped by the people who listen to it. Please tell us a bit about your experience by filling out our short listener survey: https://www.surveymonkey.com/r/SX6X8X3 **** Brought to you by Wellcome, an independent global foundation that supports science to solve the urgent health challenges facing everyone. Please visit wellcome.org for more information.

Information

  • Creator
    Wellcome
  • Years Active
    2023 - 2026
  • Episodes
    40
  • Rating
    Clean
  • Copyright
    Copyright Wellcome © 2025
  • Show Website
    When Science Finds a Way

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