The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

  1. 5 hr ago

    Jenny McCarthy | The 3 Questions You’re NEVER Supposed to Ask

    Jenny McCarthy on Reversing Autism, Healing Mold Toxicity, and the Biohacking Protocol Big Pharma Doesn't Want You to Know  Back with another long one! Autism, mold poisoning, and cognitive decline share more root causes than most doctors admit, and this episode hands you the biohacking playbook to reverse all three.  Want to try Jenny's makeup and skincare line? Visit https://bit.ly/Formless-Beauty and use code DAVE to unlock a discount.  Host Dave Asprey sits down with Jenny McCarthy Wahlberg, a New York Times bestselling author, actress, comedian, and 14-season judge on The Masked Singer who became one of the most trusted voices in the autism community after her son's regression following a vaccine reaction. She documented his recovery in books including Louder Than Words and Healing and Preventing Autism, founded the vegan, cruelty-free beauty brand Formless Beauty, and now develops unscripted television, documentaries, and podcasts with her husband Donnie Wahlberg through their Work Baby Productions banner under a first look deal with Lionsgate.  Dave and Jenny trace her son's autism diagnosis back to a vaccine reaction and walk through the biohacking protocol that helped him recover, including candida detox, activated charcoal binders, collagen and hypermobility support, and hacking his gut with a low toxin diet that removed wheat and dairy. They connect autism to mitochondria energy collapse and neuroinflammation, and explain how nootropics like modafinil restore focus without the crash of stimulants.  The conversation moves into longevity and human performance strategies for adults, covering low dose Cialis for brain blood flow, DHEA and thyroid optimization for women over 35, peptide protocols including melanotan and Retatrutide, cyclical ketosis and fasting alternatives, and why hormone replacement therapy reverses aging instead of causing cancer.  They dig into functional medicine tools for everyday life: electrolytes and salt for blood pressure and sleep optimization, blackout darkness for circadian repair, baking soda for metabolism and alkaline balance, and why Jenny trusts krill oil over fish oil for anti-aging support. Dave breaks down ibogaine and neuroplasticity for brain repair, defends his carnivore leaning diet, shares why Danger Coffee still starts his morning, and calls out AI chatbots for pushing censored health narratives.  This is essential listening for anyone interested in biohacking, human performance, longevity, functional medicine, brain optimization, and building a smarter, not harder approach to supplements and long-term health.  You'll Learn:  How mold and candida trigger PANS and PANDAS, and why they mimic autism symptoms Why activated charcoal timing determines whether it works as a binder The link between collagen, hypermobility, and leaky gut in autism and long-term brain function How modafinil, nicotine, and Cialis support brain optimization, focus, and mitochondria function Why hormone replacement therapy and DHEA reverse aging in women after 35 The truth about ketosis supplements, structured water, and alkaline water myths How darkness, light exposure, and electrolytes rebuild sleep optimization and metabolism   Thank you to our sponsors!       - ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.  - MOD | Visit https://mod.com/ for a consultation and get 10% off your first order plus free shipping with promo code DAVE.  - KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off  - Butcher Box | Go to ButcherBox.com/HUMANUPGRADE to get $20 off your first box, plus your choice of free ground beef for life, or free chicken thighs or top sirloins in every box for a year with free shipping always.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.  New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.  Keywords: Jenny McCarthy Wahlberg, autism recovery, vaccine injury, biohacking, longevity, mitochondria, neuroinflammation, candida detox, mold toxicity, activated charcoal, hypermobility, collagen, modafinil, nootropics, human performance, hormone replacement therapy, DHEA, peptides, melanotan, ketosis, fasting, functional medicine, Danger Coffee, Smarter Not Harder, Dave Asprey, anti-aging, sleep optimization, brain optimization, metabolism, carnivore, ibogaine, neuroplasticity, supplements, PANS PANDAS  Resources:    • Want To Try Jenny's Makeup And Skincare Sine? Visit https://bit.ly/Formless-Beauty and use code DAVE to unlock a discount.  • Check Out Formless Beauty On YouTube: https://www.youtube.com/@formlessbeauty  • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/   • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.    • Danger Coffee: https://dangercoffee.com/discount/dave15?  • My Daily Supplements: SuppGrade Labs (15% Off)     • Favorite Blue Light Blocking Glasses: TrueDark (15% Off)     Timestamps:   00:00 – Trailer  01:20 – The Human Upgrade Starts  07:13 – Detoxing Candida: The Turnaround  15:00 – The Anti-Vaxxer Backlash  23:02 – The Many Flavors of Autism  29:36 – Powering Up the Autistic Brain  35:59 – The Bile & Binder Protocol  43:53 – Intuition, Trust & Integrity  53:40 – Building an Ethical Beauty Brand  58:34 – Sensory Sensitivities & Clean Living  01:04:00 – Modafinil: The Focus Drug  01:13:45 – Mold Illness, Memory & Brain Health  01:18:26 – Jenny McCarthy's Show Starts  01:22:45 – Dave's Mold Poisoning Story  01:31:04 – Nicotine, Ibogaine & Biohacking Extremes  01:38:33 – When Biohacking Goes Too Far  01:45:07 – Peptides, Hormones & Anti-Aging Hacks  01:52:24 – Hormone Replacement Therapy for Women  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Jenny McCarthy | The 3 Questions You’re NEVER Supposed to Ask

  2. 2 days ago

    3 Longevity Drugs I QUIT (And the 4 I Take Instead)

    The 3 "Longevity Drugs" That Fail the Data, and 4 Repurposed Ones Worth Considering    Back with another solo episode, this one on Big Pharma! Metformin, rapamycin, and statins are three of the most trusted names in longevity, and none of them hold up the way you've been told. This episode breaks down the human data behind the drugs everyone assumes are safe, and reveals four lesser-known repurposed pharmaceuticals that might do more for your metabolism, mitochondria, and lifespan.  Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR    Dave walks through why metformin blunts the muscle-building signal your body needs from exercise, why rapamycin's stunning mouse studies fell apart in the 2025 PEARL trial, and why statins help one person in a hundred while draining the CoQ10 your mitochondria depend on. Then he lays out the yes list: tadalafil for vascular and brain health, SGLT2 inhibitors for metabolic and kidney protection, acarbose for gut and longevity markers, and low dose naltrexone for calming an overactive immune system.  Host Dave Asprey is the father of biohacking, founder of Danger Coffee and Smarter Not Harder, and a New York Times bestselling author who has spent decades studying human performance, functional medicine, and the science of not aging. As co-founder of Unlimited.Life, a concierge longevity practice that runs over $50,000 in lab work per client, he pulls back the curtain on what the data actually shows once you strip away the marketing.  This is essential listening for anyone serious about biohacking, longevity, anti-aging, human performance, brain optimization, and hacking their own biology with real supplements and functional medicine tools instead of guesswork.  You'll Learn:  Why metformin can cancel out the muscle gains from resistance training and drain your B12 for years What the 2025 PEARL trial actually found when rapamycin was tested in healthy adults Why statins carry a 100-to-1 harm-to-benefit ratio and quietly starve your mitochondria of CoQ10 How tadalafil supports nitric oxide, vascular health, and neuroplasticity at low daily doses Why SGLT2 inhibitors trigger ketosis-like metabolic effects and protect kidney function How acarbose changes gut bacteria and shows some of the strongest longevity data in mouse studies How low dose naltrexone modulates the immune system and reduces neuroinflammation How to talk to your doctor about using these drugs off-label for longevity instead of disease treatment   Thank you to our sponsors!       - ALP | Go to alppouch.com, code DAVE for 10% off.  - Timeline | Visit timeline.com/dave and get up to 20% off when you subscribe and save.  - Kinetic | Instead of pushing your system harder, Kenetik feeds your brain the ketones it craves to fuel calm clarity and steady focus. Go to drinkkenetik.com/DAVE and use code DAVE for a discount.  - Visit www.myvitalc.com/davesfav to unlock Dave’s discount  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.  New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.  Keywords: Metformin, Rapamycin, Statins, Tadalafil, Cialis, SGLT2 inhibitors, Jardiance, Acarbose, low dose naltrexone, longevity drugs, anti-aging medication, repurposed pharmaceuticals, off-label drugs, mTOR inhibitor, AMPK, autophagy, endothelial dysfunction, CoQ10, insulin resistance, mitochondrial efficiency, senescent cells, nitric oxide, neuroinflammation, vascular health, PEARL trial, Unlimited.Life  Resources:    • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/   • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.    • Danger Coffee: https://dangercoffee.com/discount/dave15?  • My Daily Supplements: SuppGrade Labs (15% Off)     • Favorite Blue Light Blocking Glasses: TrueDark (15% Off)     • Dave Asprey’s BEYOND Conference: https://beyondconference.com     • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated    • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/   • Upgrade Labs: https://upgradelabs.com        Timestamps:   00:00 – Trailer  01:01 – Intro  03:48 – Metformin  09:18 – Rapamycin  12:55 – Statins  17:28 – Statins & CoQ10  19:38 – Tadalafil  23:43 – SGLT2 Inhibitors  26:12 – Acarbose  28:40 – Low-Dose Naltrexone (LDN)  31:44 – Dosing & Recap  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    3 Longevity Drugs I QUIT (And the 4 I Take Instead)

  3. 4 days ago

    7 Brain Compounds I Take For Superhuman Focus

    Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ Try Longevity Gummies: https://www.timeline.com/partners/dave-asprey The most powerful energy compounds aren't in your local supplement store. They're sitting in Eastern European science, and Thai herbal medicine, completely ignored by an industry that only profits from what it can patent. In this video I break down 7 compounds that have transformed my energy, sharpened my focus, and kept my brain performing like it did decades ago.  You'll also learn: Why sulbutiamine gets your dopamine receptors to work harder without the crash of regular stimulantsThe overlooked amino acid that keeps glutamate and glycine in balance, and why that balance decides how sharp your thinking feelsWhy a compound most people have never heard of protects your liver's biological age, and how that quietly determines your brain energyThe orally active peptide reshaping how your body produces its own hormones, and why it could replace the need for TRT in your late twenties or thirties Thank you to our sponsors! Butcher Box | Go to ButcherBox.com/HUMANUPGRADE to get $20 off your first box, plus your choice of free ground beef for life, or free chicken thighs or top sirloins in every box for a year with free shipping always. Viome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.iRestore | Unlock your best hair & skin with @iRestorelaser and HUGE savings on iRESTORE with code DAVE at irestore.com/DAVE 00:00 – Intro 01:41 – Sulbutiamine 03:00 – Sarcosine 04:14 – Uridine 05:08 – Thunbergia Laurifolia (Trumpet Vine) 05:55 – The Muscle-Energy Connection 06:38 – Dilucene 08:08 – TUDCA 09:06 – ACE 167 Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/ TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    7 Brain Compounds I Take For Superhuman Focus

  4. 6 days ago

    Change Your Morning, Change Your Life! Hal Elrod

    Starting your weekend off right, with the king of mindset. We had to replay this one because it's too goo not to! Meet a man who makes miracles happen. Today, I’m joined in the studio by Hal Elrod, author of the international bestseller The Miracle Morning and his newest book, The Miracle Equation. After overcoming multiple near-death experiences and financial hardships, Hal channeled his adversity into helping others overcome their own challenges. His Miracle Morning approach has impacted millions of lives. On today’s episode, Hal tells us all about his updated version of The Miracle Morning. He explains SAVERS, the six foundational practices that will transform your morning and change your life. We also talk about tips for hacking your sleep, productivity, and relationships.  Hal shares the stories of his devastating car accident and rare cancer diagnosis—and the superpowers he gained from coming back to life. We explore how these near-death experiences changed his perspective on life and what he values most. He also tackles some tough questions… Should we try to help everyone? What does it mean to be a “man”? And what does it take to truly serve others? There’s so much to take away from Hal’s refreshing and optimistic perspective.  (00:03:20) Creative Ways To Hold Yourself Accountable (00:13:57) Ditching Veganism (00:21:08) Hal’s Near-Death Experiences (00:27:35) Taking Your Health in Your Hands (00:29:37) Did Hal Come Back With Superpowers? (00:31:55) Are You Supposed To Help Everyone? (00:40:51) How the Miracle Morning Changed Hal’s LIfe (00:43:42) What Does It Mean To Be a “Man”? (00:51:25) Customizing Your Morning To Meet Your Needs (00:54:05) The Six Savers for Success (00:56:53) Tips To Save Your Sleep (01:01:51) The MVP of Personal Development Practices (01:06:14) Nourishing Our Connections Sponsors -Download Dave’s Free Peptide Guide at daveasprey.com/peptide-guide. -The One Device | Use code DAVE for $10 off at theonedevice.com/dave -iRestore | Unlock your best hair & skin with @iRestorelaser and HUGE savings on iRESTORE with code DAVE at irestore.com/DAVE Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Read: The Miracle Morning and The Miracle Equation Website: halelrod.com Facebook: Hal Elrod X: @HalElrod YouTube: @HalElrod See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Change Your Morning, Change Your Life! Hal Elrod

  5. 27 Aug

    Learn THIS And You’ll Become Impossible To Trigger

    Jonny Miller on Nervous System Mastery, Grief, and Why High Performers Can't Afford to Stay Stuck in Their Heads    Your nervous system is running every decision, relationship, and reaction in your life, and you won't notice how much it's costing you until something breaks. This episode gives you the exact framework for building real nervous system mastery instead of running on autopilot until it fails.  Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR  Host Dave Asprey sits down with Jonny Miller, host of the Inner Frontier Podcast and founder of Nervous System Mastery, who has taught more than 1,000 people how to build the skills of interoception, self-regulation, and emotional fluidity. A former Silicon Valley founder turned nervous system expert, Jonny brings a rare mix of rational, data-driven thinking and deep somatic work to a field most high performers avoid entirely.  They break down why interoception, self-regulation, and emotional fluidity are the three learnable skills behind every major shift in performance, relationships, and decision-making, and why most high achievers have spent their whole lives disconnected from what's happening below the neck. Jonny introduces the half-life of reactivity, his framework for measuring how quickly someone can move from triggered back to calm, and explains how free diving became his gateway into surrender, breath work, and pressure equalization as a form of high-stakes meditation. Dave shares his own parallel journey through nervous system work, including lessons from running 40 Years of Zen and a costly business betrayal that reshaped how he reads people. Dave and Jonny also open up about grief, including Jonny's experience losing his fiancée and later his mother, and how community and co-regulation shape how fast someone actually heals.  You'll Learn:  Why interoception, self-regulation, and emotional fluidity are the three core skills behind nervous system mastery What the half-life of reactivity is and how to use it to measure real emotional progress How free diving works as a form of high-stakes meditation and a direct feedback loop for unclenching Why congruence between your inner and outer state matters more than staying composed under pressure How team intuition can be used as a practical filter in high-stakes hiring decisions Why co-regulation with friends and community can dramatically shorten the grieving process What Jonny's Breath Buddy device is designed to teach kids and families about nervous system regulation   Thank you to our sponsors!       - MOD | Visit mod.com for a consultation and get 10% off your first order plus free shipping with promo code DAVE.  - ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.  - BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle.  - Timeline | Visit timeline.com/dave to learn more about Mitopure and get 20% off your first order for a limited time.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.  New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.  Keywords: Jonny Miller, Inner Frontier Podcast, Nervous System Mastery, interoception, self-regulation, emotional fluidity, half-life of reactivity, free diving, breathwork, nervous system regulation, somatic healing, grief processing, co-regulation, congruence, trauma response, boundary setting, narcissism, hiring intuition, cold plunge, surrender, NSDR, yoga nidra, Breath Buddy, biohacking, high performance, 40 Years of Zen, psychedelic integration, Silicon Valley founder, emotional resilience  Resources:    • Nervous System Mastery Course: https://www.nsmastery.com/  • Listen To Jonny’s Podcast ‘The Inner Frontier’ at: https://open.spotify.com/show/1lGD5wIfhnE4bepja42C9S  • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/   • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.    • Danger Coffee: https://dangercoffee.com/discount/dave15?  • My Daily Supplements: SuppGrade Labs (15% Off)     • Favorite Blue Light Blocking Glasses: TrueDark (15% Off)     • Dave Asprey’s BEYOND Conference: https://beyondconference.com     • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated    • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/   • Upgrade Labs: https://upgradelabs.com     Timestamps:   00:00 – Trailer  01:10 – Losing His Fiancée  04:28 – Nervous System Mastery  11:52 – Community & Co-Regulation  17:37 – From Head to Body  22:52 – Surrender & Free Diving  28:54 – Half-Life of Reactivity  35:33 – Congruence & the $100M Lesson  38:58 – Stupidity, Narcissism & Intuition  50:22 – Biohacking Trojan Horses  59:11 – Breath Buddy & Outro  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Learn THIS And You’ll Become Impossible To Trigger

  6. 25 Aug

    Jim Kwik: If You're Using AI Like This, You're Killing Your Brain

    Jim Kwik on Memory, AI, and Why Natural Intelligence Beats Artificial Intelligence    Your brain is quietly outsourcing itself to AI, and you won't notice until it's gone. This episode gives you the exact framework to use artificial intelligence as a tool for brain optimization instead of a crutch that erodes your memory, focus, and critical thinking.  Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR  Host Dave Asprey sits down with Jim Kwik, one of the world's leading experts in memory improvement, brain optimization, and accelerated learning. For more than 30 years, Jim has served as the brain coach to professional athletes, political leaders, business magnates, and Hollywood icons, with corporate clients including Google, Nike, SpaceX, and Harvard. He hosts the Kwik Brain podcast with over 100 million downloads, reaches 200,000 people annually through live keynotes, and just wrapped his 14th annual Beyond Biohacking Conference with 5,000 attendees in Austin. Jim overcame a childhood brain injury that left him labeled "learning disabled," and turned that struggle into a mission he calls "no brain left behind."  They break down the MIT study showing that people who use AI to write and think score worse on memory and comprehension than those who rely on their own brains, and why that matters for anyone serious about longevity, human performance, and anti-aging. Jim introduces the concept of digital dementia and cognitive sovereignty, explaining how nootropics, neuroplasticity, and functional medicine can support your biology while AI still requires you to keep your own hardware sharp. They cover the MEDS Rx framework for brain optimization: meditation, exercise, diet, sleep optimization, and relationships, plus why mitochondria, metabolism, and inflammation from processed food directly impact your cognitive output. Jim also shares how his own kids use AI as a tutor rather than a replacement for thinking, and why sleep inertia and the first few minutes after waking set the tone for your entire day.  This is essential listening for anyone serious about biohacking, hacking their own brain, longevity, neuroplasticity, brain optimization, supplements, and building a Smarter Not Harder approach to human performance in the age of AI.  You'll Learn:  Why the MIT study found AI users had weaker memory and comprehension than people who did the work themselves What digital dementia and digital deduction are, and how they quietly erode your cognitive muscles How to use AI as an augmented intelligence partner instead of a replacement for critical thinking The MEDS Rx framework for brain optimization: meditation, exercise, diet, sleep, and relationships Why the first few minutes after waking determine your focus and mood for the entire day How spaced repetition and AI-assisted learning can lock in new skills and behavior change faster The HUMAN framework for staying irreplaceable in a world run by algorithms   Thank you to our sponsors!       - KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off  - Neuronic | Go to www.neuronic.online Code DAVE for $100 off  - Our Place | Upgrade your kitchen with Our Place today. Visit fromourplace.com/DAVE and use code DAVE for 10% off sitewide.  - LMNT | Check it out at drinklmnt.com/DAVE. You'll get a free 8 count sample pack with any purchase.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.  New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.  Keywords: Jim Kwik, Limitless, Kwik Brain, digital dementia, cognitive sovereignty, human intelligence, artificial intelligence, MIT AI study, brain injury recovery, accelerated learning, memory improvement, speed reading, neuroplasticity, spaced repetition, memory palace, MEDS Rx framework, sleep inertia, attentional priming, metacognition, digital deduction, brain optimization, cognitive flexibility, cognitive anti-fragility, 40 Years of Zen, biohacking, Beyond Biohacking Conference, HUMAN framework, learning how to learn, GPS dependency, mental fatigue, burnout recovery, Limitless Daily  Resources:    • Learn More About Jim At: https://limitlessdaily.com/  • Follow Jim On Instagram At: https://www.instagram.com/jimkwik/  • Watch Jim On YouTube At: https://www.youtube.com/jimkwik  • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/   • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.    • Danger Coffee: https://dangercoffee.com/discount/dave15?  • My Daily Supplements: SuppGrade Labs (15% Off)     • Favorite Blue Light Blocking Glasses: TrueDark (15% Off)     • Dave Asprey’s BEYOND Conference: https://beyondconference.com     • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated    • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/   • Upgrade Labs: https://upgradelabs.com     Timestamps:   00:00 – Trailer  00:55 – Intro  06:54 – AI as Tool, Not Crutch  13:00 – Protecting Cognitive Sovereignty  21:28 – Digital Dementia Explained  27:13 – AI-Enhanced Learning Techniques  32:18 – Speed Listening and Reading  40:38 – Rapid Tips by Age  46:59 – Building an AI Second Brain  53:04 – Burnout and Brain Optimization  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Jim Kwik: If You're Using AI Like This, You're Killing Your Brain

  7. 23 Aug

    The Most Important Longevity Molecule I've Ever Found

    Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ Try Longevity Gummies: https://www.timeline.com/partners/dave-asprey Most people see the physical decline of aging as an inevitable process that can only be managed with medications, but this video cuts through that assumption by explaining that the smartest minds in science, including multiple Nobel Prize winners, have identified a single root cause of aging tied to a specific molecule called NAD+. You'll also learn: Why your body actively destroys NAD+ faster as you age, and why that's the real driver of fatigue and brain fogHow the gap between NAD+ production and destruction widens every year, quietly draining your cellular energyThe early signs your NAD+ levels are already too low, from slow-healing skin to workouts that take days to recover fromWhat actually flips your body's NAD+ production back on, and the exact order of diet, fasting, exercise, and supplementation that makes it work Try Danger Creatine: https://dangercoffee.com/products/danger-creatine Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/discount/davetube Try Suppgrade Labs: https://shopsuppgradelabs.com/ Thank you to our sponsors! ECHO Water | Go to http://echowater.com/daveand use code DAVE10 for 10% off your ECHO Flask.Viome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Timestamps: 00:00 – The Aging Molecule 01:03 – The War Within Your Cells 03:28 – Builder vs. Demolition Crew 04:34 – NAD+ and Brain Function 06:00 – Root Cause Over Symptoms 08:31 – Fixing the Imbalance 10:10 – Fasting for NAD+ 11:30 – The REHIT Protocol 12:37 – The Supplementation Step Connect with Dave Asprey! Website: https://daveasprey.com TikTok: https://www.tiktok.com/@daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/daveaspreybpr The Human Upgrade Podcast: https://www.instagram.com/ TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/ Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15 Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    The Most Important Longevity Molecule I've Ever Found

  8. 21 Aug

    The Scientist Monk: Gurudev Sri Sri Ravi Shankar

    This Friday, I had to play back an all-time favorite. I was honored and grateful to bring you a conversation that I recorded in person with Gurudev Sri Sri Ravi Shankar at the Art of Living Center in Los Angeles.  Gurudev Sri Sri Ravi Shankar is a leader of an international movement with more than 50 million followers who do breathwork every single morning. He has worked for 40 years as a global ambassador for peace at the highest levels.  I did his breathwork exercises every morning without fail for five years while fixing my mind, body and nervous system, and I have a huge amount of respect for his work in the world. It was a joy to chat with him in person and his childlike curiosity, enthusiasm for teaching, and deep understanding of the world are echoed in every word of this episode.  Gurudev is a true visionary, so I am grateful that he set aside time to talk with me so I could share his wisdom with you.  Thank you to our sponsors!       -Qualia | If you want to take the guesswork out of maintaining high NAD+ levels as you age, go to www.qualialife.com/daveNAD to get clinically proven Qualia NAD+ backed by a 100 day money back guarantee and code DAVENAD at checkout gets you an extra 15% off. -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.  New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.  Keywords: Sri Sri Ravi Shankar, Dave Asprey, Art of Living, Sudarshan Kriya, breathwork, pranayama, meditation, non-dual consciousness, gut feeling intuition, biohacking, quantum physics consciousness, Nobel Prize physics, curiosity and childlike wonder, skepticism vs cynicism, scientific temper, dogmatism, veterans PTSD breathwork, SKY campus happiness program, violence prevention, community building, dating apps romance, Elon Musk Mars, computer chip brain implant, duality and consciousness, equanimity, ego and inner voice, spirituality and science, yoga philosophy, guru interview, positive energy radiation, transcending fear   Resources:    • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/   • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.    • Danger Coffee: https://dangercoffee.com/discount/dave15?  • My Daily Supplements: SuppGrade Labs (15% Off)     • Favorite Blue Light Blocking Glasses: TrueDark (15% Off)     • Dave Asprey’s BEYOND Conference: https://beyondconference.com     • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated    • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/   • Upgrade Labs: https://upgradelabs.com        Timestamps:   00:00 - Trailer 01:11 - Curiosity & Skepticism 03:42 - Reality, Physics & Illusion 06:34 - Non-Dual Consciousness 08:37 - Origins of Breathwork 13:36 - Trusting Your Gut Feeling 14:28 - Violence, Peace & Veterans 19:54 - Romance & Dating Apps 23:44 - Science Behind Meditation 27:27 - Fear of the Unknown See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    The Scientist Monk: Gurudev Sri Sri Ravi Shankar
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For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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