Forever Young

Forever Young
  • 0.0 (0)
  • Health & Fitness

Sharing the science of longevity with a healthy dose of humanism. Helping you cut through the noise and explore our species' deepest fears, greatest hopes, and wildest dreams. foreveryoungfilm.substack.com

  1. 11 Aug

    Epigenetic reprogramming reaches humans, how other people keep us alive, and the memory slip everyone misreads

    In our film Forever Young, Ava receives an annual epigenetic treatment and leaves the clinic a year younger than she arrived. We wrote that as fiction. In June, Life Biosciences dosed the first human being with a partial epigenetic reprogramming therapy. This is just one of many topics covered in our AMA with Dr. Thomas Lewis. Dr. Thomas Lewis is a psychiatrist and neuroscientist, co-author of A General Theory of Love, and a co-star and producer of the film. You sent the questions. He answered. Two notes on accuracy The reprogramming trial discussed is a Phase 1 safety study run by Life Biosciences, which David Sinclair co-founded. The FDA cleared the application in January 2026, and the first participant was dosed on June 9. Clearance to begin a trial is not approval of a therapy. On dementia genetics, Dr. Lewis describes research showing no genetic difference in people highly resistant to cognitive decline. That reflected the literature when he learned it. The largest study to date, published in January 2026 across 18,080 participants, found such people were 19 percent less likely to carry the APOE-e4 variant. His broader point holds. Genetics accounts for far less of dementia risk than was assumed a decade ago, though it is not absent. The longevity revolution is moving fast. Don’t fall behind. Join the readers who want the full picture → Forever Young is streaming worldwide. Haven’t watched it yet? Click below to pick your platform. Sources Nothing here is medical advice. Evidence suggests several of the interventions discussed may support healthspan, and each one should be discussed with your physician before you act on it. Leone M, Barzilai N. An Updated Prioritization of Geroscience-Guided FDA-Approved Drugs Repurposed to Target Aging. Medical Research Archives. 2024;12(2). Durant A, et al. Evaluating the association of apolipoprotein E genotype and cognitive resilience in SuperAgers. Alzheimer’s & Dementia. 2026;22(1). Newman SJ. Morbid: Debunking Modern Longevity Science. 2026. Lewis T, Amini F, Lannon R. A General Theory of Love. Random House, 2000. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit foreveryoungfilm.substack.com/subscribe

    Epigenetic reprogramming reaches humans, how other people keep us alive, and the memory slip everyone misreads

  2. 4 Aug

    The next generation of Brain-Computer Interfaces (BCIs) will aid in memory and more

    A brain-computer interface reads the electrical activity of neurons and passes that signal to a machine. Two are in routine clinical use and are rarely called brain implants: cochlear implants, which let deaf people hear, and deep brain stimulation, used for Parkinson’s and severe depression. More than a million people have one. Newer systems are returning movement to people with paralysis and speech to people who cannot speak. Research now targets memory and cognition, and eventually direct connections between brains and machines. In this video, artist Taryn Southern and Dr. Thomas Lewis, a psychiatrist and neuroscientist, discuss where the technology stands and how far it could go. The longevity revolution is happening fast. Don’t get left behind. KEEP LEARNING: This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit foreveryoungfilm.substack.com/subscribe

    The next generation of Brain-Computer Interfaces (BCIs) will aid in memory and more

  3. 24 Jun

    Scientists Are Building a $100 Test for How Fast You're Aging

    Your doctor can measure almost everything about your health — blood pressure, cholesterol, bone density. But what about how fast you’re aging? There’s no test for that. Yet. In this video, Dr. Brianna Stubbs of the Buck Institute for Research on Aging explains why our best aging tests fall short — each one captures only a sliver of the picture — and how a Stanford-led coalition called THRIVE is building a single, at-home score for the whole person: a concept known as intrinsic capacity. One number, built to predict the next 20 years of your health, that will let doctors treat aging at its root before decline sets in. It’s one of the most ambitious programs in geroscience, and if they succeed, it will impact millions of people worldwide. Watch Brianna and a cast of top longevity experts in our award-winning documentary Forever Young, now available on Apple TV and Amazon. 🎬 Watch the full documentary — Forever Young — now streaming: This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit foreveryoungfilm.substack.com/subscribe

    Scientists Are Building a $100 Test for How Fast You're Aging

  4. 12 Apr

    The Thoughts That Age You (And the Practice That Slows Them Down)

    This is a free preview of a paid episode. To hear more, visit foreveryoungfilm.substack.com Most people think of meditation as a stress-reduction tool. Something you do in an app, on a cushion, before a hard day. A nice habit, loosely supported by science. Dr. Thomas Lewis wants to correct that framing entirely. In this video, Dr. Thomas Lewis breaks down the neuroscience of meditation — and why it reaches further into your biology than most peo…

    The Thoughts That Age You (And the Practice That Slows Them Down)

  5. 22 Mar

    Love, Longevity, and the Wellness Trend He Calls a Total Scam — Dr. Eric Verdin, Unfiltered

    Dr. Eric Verdin is one of the scientists at the heart of our award-winning documentary Forever Young. He’s also president and CEO of the Buck Institute for Research on Aging. After a private screening of the film, director David Donnelly sat down with Verdin for a live virtual Q&A with the audience. No talking points. Just an hour of unfiltered conversation with one of the most respected minds in longevity science. In this conversation, Verdin reveals: * The longevity variable most people completely overlook — and why he’s building an entire research center around it * Why your outlook on life isn’t just a mood issue — and what the science says it’s actually doing to your body * On the realities of GLP-1 agonists, V02 max, and other topics that have captivated popular culture * The booming wellness trend he calls a total scam — and why it makes him furious every time he walks past one Plus: what’s actually coming in anti-aging medicine, the real science on fasting, and what an approved longevity drug could look like within five years. This is just the beginning. Dr. Verdin mentioned something in passing that most people don’t fully register: the biology of aging can be modulated. One of the most extraordinary examples of that happening right now is at his own institution — the Buck Institute’s work on senescent cells, the so-called “zombie cells” that accumulate in your body as you age, quietly driving inflammation, accelerating disease, and shortening your life. Scientists now have drugs that can selectively eliminate them. In animal models, the results are extraordinary. Paid subscribers get access to that interview as well as our full archive of 100+ videos and articles that give insider access to the drugs, treatments, science, and philosophy driving the most exciting revolution of our lifetime. The longevity revolution is moving fast. Don’t fall behind. Join the readers who want the full picture → This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit foreveryoungfilm.substack.com/subscribe

    Love, Longevity, and the Wellness Trend He Calls a Total Scam — Dr. Eric Verdin, Unfiltered

  6. 20 Mar

    Purpose, Meaning, and the Psychology of a Life Well Lived

    This is a free preview of a paid episode. To hear more, visit foreveryoungfilm.substack.com In this inaugural Forever Young Substack Live, Dr. Thomas Lewis — psychiatrist, neuroscientist, and co-author of A General Theory of Love — spent 45 minutes answering live audience questions on what actually determines how long we live and how well. What emerged was part clinical insight, part cultural criticism, part longevity science. Tom covered the p…

    Purpose, Meaning, and the Psychology of a Life Well Lived

  7. 12 Mar

    THE CAMBRIDGE CONVERSATION: Steve Horvath, Adrian Liston, and Gabriele Kaminski Schierle on the Future of Aging

    This is a free preview of a paid episode. To hear more, visit foreveryoungfilm.substack.com Steve Horvath created the epigenetic clock — the molecular tool that, for the first time, made it possible to measure biological age rather than simply count the years a person has been alive. His 2013 paper is among the most-cited in aging research, and his current work at Altos Labs in Cambridge focuses on whether the clock can not only measure aging …

    THE CAMBRIDGE CONVERSATION: Steve Horvath, Adrian Liston, and Gabriele Kaminski Schierle on the Future of Aging

  8. 10 Feb

    Stanford's Top Longevity Psychologist on Building a New Map for Life

    This is a free preview of a paid episode. To hear more, visit foreveryoungfilm.substack.com After a recent screening of Forever Young, director David Donnelly sat down with Dr. Laura Carstensen for a live Q&A with the audience. Our ancestors gave us 30 extra years of life. So what are we doing with it? We’ve kept the same life script — education, then work, then retirement — and just stretched it at the seams. Dr. Carstensen thinks that’s a mistak…

    Stanford's Top Longevity Psychologist on Building a New Map for Life
See All (19)

About

Sharing the science of longevity with a healthy dose of humanism. Helping you cut through the noise and explore our species' deepest fears, greatest hopes, and wildest dreams. foreveryoungfilm.substack.com

Information

  • Creator
    Forever Young
  • Years Active
    2026
  • Episodes
    19
  • Rating
    Clean
  • Copyright
    © Forever Young Movie, LLC.
  • Show Website
    Forever Young