Siim Land Podcast

Siim Land

Siim Land is an author, speaker, and consultant. He talks about optimizing health, performance, and longevity with different techniques and biohacking.

  1. 3D AGO

    #504 How to Keep Your Skin Young Without Expensive Treatments - Dr. Alexis Ortega

    Dr. Alexis Ortega is board-certified in longevity, regenerative and aesthetic medicine. He has a clinic Ad Astra in Barcelona, Spain. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Intro 00:55 How to counteract age-related loss of facial harmony aside from just wrinkles 12:30 Does growth hormone change the face 18:10 Bon Charge sponsorship 19:17 What's the minimum effective dose of at-home skincare — the three things that actually move the needle? 21:28 Retinoids 24:05 Skin barrier support 27:00 Effect of sun exposure on extrinsic skin aging 31:02 Best evidence-based sunscreen ingredients 34:34 List of best sunscreen ingredients 36:00 Worst sunscreen ingredients 37:45 Daily sunscreen vs using the UV index as a guide 39:43 Do people overuse skincare products 42:33 Castor oil, beef tallow and egg yolks for skin 49:08 Are natural sunscreens effective 49:59 If someone had unlimited money today, what are the most promising rejuvenation interventions actually available? 51:08 What diagnostics Alexis would do with an unlimited budget 54:30 Rejuvenation therapies Alexis would do 55:18 Alexis approach to peptides 56:00 Intravenous senolytics 56:20 NAD injections 57:14 What you can do now to practically extend lifespan 59:40 Intravenous exosomes 01:00:25 Therapeutic plasma exchange 01:03:06 Stem cell therapy 01:05:30 Gene therapies 01:07:48 What biomarkers matter most for predicting long-term health Alexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/

    1h 14m

  2. MAY 1

    #503 Scientists Analyzed 400 Drugs — Only 14 Were Linked to Longer Life - Dr. Kevin Perez

    Dr. Kevin Perez is a computational biologist working at the cutting edge of aging science and drug discovery. His work focuses on aging research, drug repurposing, and integrating complex multi-omics data to better understand how we can extend healthspan. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Intro 00:47 Kevin’s study about pharmaceuticals that are associated with reduced mortality 10:17 Which class of drugs had reduced mortality 13:07 Bon Charge sponsorship 14:12 How Kevin researches longevity molecules 16:37 Estrogen’s longevity effects 17:37 How Kevin started researching dog aging 25:32 Chemical reprogramming 29:32 Kevin’s understanding of what causes aging 34:52 Metformin vs SGLT2 inhibitors 38:37 Erectile dysfunction drugs 43:02 Over the counter supplements with longevity effects 45:52 Biological age clocks 50:02 What Kevin thinks is the best biomarker of aging 54:32 Composite biological age vs combination of multiple markers 59:32 Kevin’s new study plans 01:02:52 What Kevin wishes he adopted sooner Start rewinding your biological clock: https://www.siimland.co/course P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

    1h 7m

  3. APR 24

    #502 What the Most Promising Longevity Drug Did for Humans - Dr. Brad Stanfield

    Join our LONGEVITY Community: https://www.skool.com/longevity-society Timestamps: 00:00 Intro 00:37 Why Brad crowd funded a rapamycin trial 03:22 What Brad’s rapamycin trial found 12:57 Why rapamycin blunted the effects 17:17 Rapamycin effects on grip strength 19:57 Rapamycin and immune effects 21:47 Effects on biomarkers 25:22 Brad’s thoughts on rapamycin moving forward 31:52 Metformin exercise effects 32:52 Other medicines with longevity potential 36:37 Medicines that move the needle the most for people 45:17 Will Brad do another study 48:27 Brad on GLP-1s Dr Brad Stanfield is a family medicine doctor in New Zealand: https://www.youtube.com/@DrBradStanfield Bloodwork for longevity panel discussion: https://youtu.be/7QONBQCpRJ0 My 2026 longevity routine: https://youtu.be/OceysodInIo Start rewinding your biological clock: https://www.siimland.co/course

    53 min

  4. APR 17

    #501 Sleep, Circadian Rhythm & What Actually Works (Q&A with Dr. Greg Potter)

    Dr. Greg Potter has a PhD from the University of Leeds in sleep, nutrition, and metabolism. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Intro 00:45 Catchup 02:05 Are circadian rhythms nature or nurture 09:55 What’s ideal timing of sunlight exposure for circadian anchoring 15:25 Bon Charge sponsorship 20:30 Does creatine increase DHEA or DHT levels 25:50 Does creatine reduce sleep quality 33:25 Greg’s new podcast 36:15 Is more REM sleep better 42:05 How to optimize REM sleep 44:25 What % of different sleep cycles should we get (light, deep, REM) 46:10 Is food processing good or bad 52:45 Incline bed therapy 55:20 Is it bad to use sleep herbs 58:45 Does melatonin supplementation stop natural production 01:01:15 What to do if you wake up at night and can’t fall back asleep Greg Potter YouTube Channel: https://www.youtube.com/@gregpotterphd

    1h 3m

  5. APR 10

    #500 After 25 Years of Brain Scans, Here’s What Separates High Performers - Dr. Andrew Hill

    Dr. Andrew Hill has a PhD in Cognitive Neuroscience from UCLA and has extensive experience in the field of neurofeedback and QEEG. He founded the Peak Brain Institute. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Intro 00:45 — Andrew's new book Gifted and Tortured 04:47 — Diagnosis vs resource-based brain optimization 06:20 — The 12 core brain phenotypes 07:57 — The stabilizer and supervisor: executive and sleep control 10:23 — CEO and lifeguard phenotypes: hyperfocus, anxiety, and stuck thoughts 12:41 — Language and auditory processing phenotypes 14:53 — Bon Charge sponsorship 16:00 — Phenotypes exist on a spectrum 17:03 — Brain speed, memory, aging, and sleep-related brain fog 20:15 — Interventions: sleep, meditation, supplements, and neurofeedback 21:46 — The most common phenotypes Andrew sees 26:30 — Supplements, stimulants, and nootropics 29:24 — Why Andrew prefers training the brain over relying on meds 32:26 — How accurate is self-diagnosis? 35:12 — Sleep trackers, self-awareness, and measuring how you feel 36:11 — Peak performance and flow states 41:19 — Using phenotype to train smarter and recover better 42:34 — Siim’s brain scan begins 44:40 — What the brain map shows: fatigue, hyperfocus, and executive traits 48:57 — Siim’s speed and focus test results 53:20 — Andrew’s own brain phenotype and ADHD story 58:20 — Can focus be trained? 01:03:18 — Main takeaway: understanding your brain creates agency Dr. Andrew Hill YouTube channel: https://www.youtube.com/@DrHillMy 2026 longevity routine: https://youtu.be/OceysodInIo Start rewinding your biological clock: https://www.siimland.co/course P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

    1h 7m

  6. APR 3

    #499 Humans Aren’t Supposed to Live This Long (Grandmothers Might Explain Why) - Dr Kristen Hawkes

    Professor Kristen Hawkes is a pioneering anthropologist whose work helped bring the grandmother hypothesis to the spotlight of human evolution research. Through fieldwork and evolutionary theory, she argued that older women may have played a crucial role in shaping the human life course, not just by living longer, but by helping feed and support grandchildren. That idea helped reframe menopause, longevity, and family cooperation as possible drivers of what makes humans distinct and what explains our longer lifespans. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Intro 01:05 How Kristen started to think about the paradox of grandmother longevity 09:15 What accounts for variation in adult mortality across lifespan 13:40 Difference in male and female longevity 17:20 Why human babies are very dependent 20:05 Bon Charge sponsorship 21:10 Dynamics of human social evolution and longevity 23:05 How longer weening period in human babies contributes to our intelligence 29:35 Weening and intelligence 34:25 Evolutionary explanation for grandparents 36:35 The contribtion of hunting success vs gathering to children size in Hadza 47:05 Does the grandmother hypothesis make sense 48:15 Role of DHA and seafood in human brain evolution 51:35 Social hierarchy of grandparents in the Hadza 56:01 Grandfathers 01:08:35 Role of grandparents in the modern world My 2026 longevity routine: https://youtu.be/OceysodInIo Start rewinding your biological clock: https://www.siimland.co/course

    1h 19m

  7. MAR 28

    #498 Lifestyle Adds 5 Years To Your Life, But This Determines the Rest (Physicist Explains) - Dr Uri Alon

    Dr. Uri Alon is a physicist-turned-biologist, a professor at the Weizmann Institute, and one of the leading thinkers exploring how complex biological systems work. In this episode, we discuss his research on the effects of genetics, lifestyle, environment, and luck on human lifespan. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Intro 00:55 How big of a role does genetics play in longevity 06:25 How important is lifestyle vs genetics 08:25 How big of a role does lifestyle play in longevity 12:55 Why is lifestyle less impactful than genetics 15:25 Bon Charge sponsorship 16:30 Genes of people who live to 110 18:55 Why lifestyle matters a lot if you have bad genes 21:45 What leads to aging 22:45 What’s the maximum human lifespan 25:20 Why nobody has lived over 122 yet 27:05 Strategies to extend lifespan beyond normal 34:05 What made Uri interested in longevity as a physicist 36:25 Recurring patterns in human longevity and aging 38:40 Simplest analogie for aging 49:15 Surprising role of luck in longevity 54:55 How to practically extend your lifespan 59:30 What Uri needs to discover next about aging Dr Uri Alon Lab YouTube channel with Systems Aging courses: https://www.youtube.com/@alonlab9733/videos My 2026 longevity routine: https://youtu.be/OceysodInIo Start rewinding your biological clock: https://www.siimland.co/course P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

    1h 5m

  8. MAR 22

    #497 The Complete Longevity Ranking: Lifestyle, Medicine, Biohacking

    Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/ Timestamps: 00:00 Intro 00:36 Lifestyle bracket 06:50 Lifestyle bracket winners 11:47 Join my online community 18:46 Medicine / pharmaceutical bracket 19:20 Medicine /pharmaceutical bracket winners 22:32 Geroscience bracket 33:13 Geroscience winners 35:00 Biohacking bracket 40:16 Biohacking bracket winners 43:04 Final 8 winners 46:32 Final 4 winners 49:23 Final 2 winners Vote yourself for the Longevity Bracket: https://www.optispan.life/longevity-bracket My 2026 longevity routine: https://youtu.be/OceysodInIo Start rewinding your biological clock: https://www.siimland.co/course

    53 min
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4.8
out of 5
197 Ratings

About

Siim Land is an author, speaker, and consultant. He talks about optimizing health, performance, and longevity with different techniques and biohacking.

Information

  • Creator
    Siim Land
  • Years Active
    2017 - 2026
  • Episodes
    519
  • Rating
    Clean
  • Copyright
    © Siim Land
  • Show Website
    Siim Land Podcast

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