The Evidence Based Rheumatology Podcast

Michael Putman
  • 4.9 (115)
  • MEDICINE
  • UPDATED SEMIMONTHLY

A weekly podcast for physicians interested in evidence based medicine and rheumatology. Find the papers at ebrheum.com

  1. JAN 21

    E131: A Sham-Controlled Sham of a Trial: RESET-RA

    Today I cover the recent publication of the RESET-RA study, which evaluated vagal nerve stimulation to treat rheumatoid arthritis. Have a listen in full, but let me be clear upfront: I do not think this works and will not be referring any patients to receive it. This will forever be my pivotal example of the effect of unblinding, but would love to hear if you think different!    Paper: https://www.nature.com/articles/s41591-025-04114-7 Supplement (see S4): https://www.nature.com/articles/s41591-025-04114-7#Sec27

    15 min

  2. 12/22/2025

    E130: Telitacicept for SLE

    Surprisingly (unbelievably?) impressive RCT evaluating the Blys/APRIL inhibitor "telitacicept" for patients with SLE (mixed SLE and SLE-LN). Very curious to see where the FDA goes with this one.    Paper: https://www.nejm.org/doi/full/10.1056/NEJMoa2414719

    13 min

  3. 12/04/2025

    E129: Long Term Routine Laboratory Monitoring in RA

    Ever wonder how often you really need to check "monitoring" labs? If so then this is the podcast for you! Bryant England mentioned this during his excellent Year in Review session at ACR Convergence 2025. I've been meaning to cover it and finally got around to doing so. Have a listen and share with friends!   Paper: https://pubmed.ncbi.nlm.nih.gov/40854212/

    15 min

  4. 11/12/2025

    E128: Nerandomilast for Autoimmune ILD (FIBRONEER-ILD)

    Covering a very interesting study this week, which investiaged the PDE4B inhibitor nerandomilast for patients with progressive pulmonary fibrosis (specifically including 325 patients with autoimmune ILD). Would have been yet another ho hum trial if not for the big reveal... have a listen to find out! Article: https://www.nejm.org/doi/full/10.1056/NEJMoa2503643

    19 min

  5. 09/22/2025

    E127: TNFs and All That CHF

    Another episode looking into safety this week! Tackling that pesky issue of TNFs and CHF. Be sure to subscribe to my newsletter and check out the papers below!    Newsletter: https://sprw.io/stt-ee87b4 ATTACH: https://pubmed.ncbi.nlm.nih.gov/12796126/ RENEWAL: https://www.ahajournals.org/doi/10.1161/01.cir.0000124490.27666.b2 Observational Studies: https://pubmed.ncbi.nlm.nih.gov/23155221/

    22 min

  6. 09/08/2025

    E126: Risk Signals, JAKs, and SELECTIVE-ity

    Covering an interesting but ultimately disappointing post hoc study of multiple upadacitinib trials in RA. Initially some hope for clarity in the "Do JAKs cause all the badness?" questions, but ultimately landing me about where I have been since ORAL-SURVEILLANCE was published Paper: https://www.sciencedirect.com/science/article/pii/S0003496724423091

    15 min

  7. 06/29/2025

    E125: Adrenal Insufficiency after Stopping Prednisone

    Interesting read this week - I cover a nifty little paper that presented data about adrenal insufficiency after stopping prednisolone, published in JAMA Open in March 2025.     Open Access Journal Here: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831668

    18 min

  8. 06/12/2025

    e124: MTX vs Pred for Pulmonary Sarcoidosis: PREDMETH Study

    Interesting NEJM trial this week comparing methotrexate to prednisone for pulmonary sarcoidosis. Paper available here: https://www.nejm.org/doi/full/10.1056/NEJMoa2501443

    14 min
See All (100)

4.9
out of 5
115 Ratings

About

A weekly podcast for physicians interested in evidence based medicine and rheumatology. Find the papers at ebrheum.com

Information

You Might Also Like