The Obesity Guide with Matthea Rentea MD

Matthea Rentea MD
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Matthea Rentea MD leads discussions on obesity and chronic weight management. Her guests range from experts in the fields that intersect with obesity and wellness, to individuals successful in their weight journey. She is a Board certified Internal Medicine and Diplomate of the American Board of Obesity Medicine and founder of the Rentea Metabolic Clinic, a Telehealth clinic for residents of the state of Indiana and Illinois that helps comprehensively with weight management. This podcast is for information and education purposes only. No medical advice is being given. Please talk to your physician for what is right for you. 

  1. 1D AGO

    Perimenopause, GLP-1s, and What's Actually Affecting Your Sex Drive with Dr. Kristen Wolfe

    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. If you've noticed your sex drive has tanked, whether from GLP-1s, perimenopause or menopause, postpartum changes, or simply the mental load of being a woman in 2026… you're not imagining it. And you're definitely not “broken”. In this episode, I talk with Dr. Kristen Wolfe, OB-GYN and women's sexual health specialist at Evermore Women's Health. She breaks down why 85% of women experience desire differently than we're told and what’s actually behind the drop in libido so many women experience. We talk about how hormones, stress, medications, busy lives, and relationship dynamics all play a role, and why so many women blame themselves for changes that are completely normal. Dr. Wolfe also shares practical strategies that can help, from understanding responsive desire and reducing the “brakes” on libido, to scheduling intimacy, practicing mindfulness, and using tools like arousal creams or medical treatments when appropriate. References Connect with Dr. Kristen Wolfe https://www.evermorewomenshealth.com/ https://www.kristenwolfemd.com/ Books: Come As You Are — Emily NagoskiYou Are Not Broken — Kelly CaspersonA Tired Woman’s Guide to Passionate Sex — Laurie MintzBetter Sex Through Mindfulness — Lori BrottoBecoming Cliterate — Laurie MintzOnline resources: Dipsea, an app offering erotic audio stories designed for womenOMGYes, an educational platform where women share techniques and insights about pleasure and orgasmThe International Society for the Study of Women's Sexual Health (ISSWSH)Products: Vella Bioscience Überlube Documentary: All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I’ve Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you. Support the show

    57 min

  2. FEB 9

    Understanding PCOS: From Diagnosis to Long-Term Health with Dr. Sabrina Huq

    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. If you’ve been told you have PCOS (or suspect you might), you’ve probably been left with more questions than answers. It’s one of the most misunderstood conditions out there, and a lot of people are misdiagnosed, under-treated, or given the same tired advice: “just lose weight” or “take the pill and see.”  In this episode, I’m joined by endocrinologist Dr Sabrina Huq to clear things up. We talk about what PCOS actually is, how to get properly diagnosed (including the key lab tests), and why spotting it early can change your long-term health, including your ability to have a healthy, natural pregnancy. Tune in for Dr Huq’s practical approach to managing PCOS through food, movement, sleep and stress, plus when meds like metformin or GLP-1s might make sense. References Flo.health  Connect with Dr. Sabrina Huq: Instagram Tiktok Clinic Audio Stamps 01:08 – Dr. Sabrina Huq introduces herself and her approach to treating PCOS patients. 02:26 – What PCOS actually is and why you don't need ovarian cysts to have it. 06:45 – The essential labs to diagnose PCOS and rule out serious conditions. 15:15 – Diet strategies for elevated blood sugar: why breakfast and whole foods matter. 22:34 – Exercise that works: strength training three times weekly and post-meal movement. 27:35 – Why stress management and sleep quality are critical for PCOS symptoms. 28:45 – Hidden endocrine disruptors in plastics and takeout + simple swaps to reduce exposure. 32:57 – Dr. Huq's supplement approach: prenatals and vitamin D over trendy options. 38:12 – What CGM reveals about insulin resistance in PCOS patients. 43:06 – Why early diagnosis matters and the reality of GLP-1s for young PCOS patients. All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I’ve Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you. Support the show

    49 min

  3. FEB 6

    Your Friday Five: Season One Wrap + A Short Hiatus

    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I’ve Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you. Support the show

    4 min

  4. FEB 2

    The Cost of GLP-1s is Forcing Switches: Can You Maintain Your Results?

    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. What happens when the medication that's finally helping you is no longer affordable? If you've had success on Mounjaro or Zepbound but need to switch to a more affordable option like Ozempic for maintenance, you're probably wondering: will this actually work? And if semaglutide didn't help you before, the idea of going back can feel risky, especially when you're worried about regaining weight, increased food noise, or losing the progress you've worked so hard for. In this episode, I break down when switching medications for cost makes sense, when it's likely to backfire, and what your options are if semaglutide is the only affordable option.  References https://www.orchardpond.com/ The 30/30 Program (Sept 2026 registration now open) Audio Stamps 01:08 - Update on Dr. Rentea's retreat planning, plus her new favorite granola discovery. 05:03 -  Listener question: Switching from Mounjaro to Ozempic for long-term maintenance due to cost. 05:59 - When it makes sense to switch medications for affordability (and when it doesn't). 08:03 -  If semaglutide is your only option: combining GLP-1s with oral medications. 10:48 - Oral (daily) Wegovy vs injections: does steadier dosing actually help? 11:40 - Why no medication is perfect and working with the right clinician is key. 12:58 - The real reason behind this work: preventing disease, not chasing a number on the scale. 14:05 - September 30/30 program update: early registration + monthly Q&A access. All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I’ve Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you. Support the show

    17 min

  5. JAN 30

    Your Friday Five: Cozy Protein Favorites, Movie-Night Snacks & a Surprise Soda

    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. Welcome back to Your Friday Five — a quick roundup of products I’ve been loving lately, especially when it comes to easy ways to add more protein. Here’s what’s in my current rotation: • Devotion Nutrition Protein Powder – My go-to for protein hot chocolate. Mix hot water, a splash of milk or milk alternative, one scoop of protein, and blend for a cozy 20-gram protein treat. If you use code DrMatthea at checkout you save.  • Meal Boosters Savory Protein Powder (White Cheddar) – Perfect on popcorn for movie nights. Tastes just like classic white cheddar seasoning and adds easy protein without sacrificing flavor. • Joyburst Protein Soda – said the name wrong on the episode but correctly written here, 20 calories, 4 grams of protein per can. Found at Costco and surprisingly became a regular favorite for both adults and kids. Cookbooks I recommend: • Skinnytaste High Protein: 100 Healthy, Simple Recipes to Fuel Your Day • Devotion Nutrition Cookbook Have a great weekend — I’ll see you Monday as we head into February! All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I’ve Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you. Support the show

    6 min

  6. JAN 26

    Weight Loss Stalled on GLP-1? Focus On THIS Instead

    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. Some of the best conversations start with listener questions, especially the ones that come from feeling stuck, confused, or wondering, 'is this normal?' In this special Q&A episode, I'm tackling two listener questions. One is about unexpected dryness while taking a GLP-1 medication. The other is a much bigger one: what to do when weight loss slows down after an initial drop, even though you feel like you’re trying. Join me as I talk about the importance of success beyond the scale, why BMI is useless without body composition data, and why movement matters more for your brain than your waistline. If you’ve been feeling frustrated, stalled, or unsure what to focus on next, this episode will help you think about your situation a little differently. References The Body Intelligence Blueprint  Audio Stamps 00:29 – 30/30 program updates and changes for the September round. 03:40 – Dry lips and skin on Zepbound: what's normal vs. what needs medical attention. 05:28 – Redefining success beyond the scale and celebrating non-scale victories. 07:15 – Why body composition data matters more than BMI for tracking real progress. 08:07 – Exercise as a tool for emotional resilience and stress management. 09:58 – Why checking labs and ruling out physiological causes should always come first. 11:46 – Introducing the Body Intelligence Blueprint: personalized one-on-one coaching with genome analysis and body composition. All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I’ve Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you. Support the show

    15 min

  7. JAN 23

    We Are Not Chasing Suppressed Hunger

    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. In today’s quick Friday Five episode, we’re talking about something that causes fear for so many people on a weight loss journey: hunger. If hunger starts returning, many people immediately assume something has gone wrong — that the medication is failing, that weight regain is inevitable, or that they’re losing control. But hunger is not a problem to eliminate. Hunger is normal. It’s natural. And it’s necessary. In this episode, we explore why chasing lifelong appetite suppression isn’t realistic, why grazing often keeps you undernourished and unsatisfied, and how learning to live in harmony with hunger is a key part of long-term weight management. You’ll hear why hunger doesn’t mean failure, how diet culture taught us to fear it, and what it actually looks like to respond to hunger with trust instead of panic. We also discuss practical strategies like structured meals, adequate hydration, gentle planning, and why eating full meals — not constant snacks — helps your body feel safe and nourished. Finally, I share resources that helped reshape my own thinking around hunger, including Words to Eat By and Food and Feelings, along with reminders about accessible support through libraries, journaling, and therapy.  We are not chasing suppressed hunger for life.  We are learning how to work with our bodies — not against them. All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I’ve Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you. Support the show

    8 min

  8. JAN 19

    Oral Wegovy: How to Take It, Who It's For, and What It Costs with Joseph Zucchi, PA

    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. We finally have the first-ever FDA-approved oral GLP-1 for treating obesity, and it's a much bigger deal than the headlines suggest… In this episode, I'm joined by Joseph Zucchi, PA, a clinical supervisor at a weight management clinic who lives and breathes the data behind obesity care. We break down oral Wegovy in practical terms: the real weight loss data, how it compares with weekly injections, why it’s different from Rybelsus, and who it’s best suited for. We also cover cost, insurance disruptions, and what to realistically expect if you’re considering a switch. If you’re trying to make sense of your options in a fast-changing landscape, whether due to coverage changes, injection concerns, or simple confusion — this conversation helps break it all down using real data. References Connect with Joseph Zucchi, PA Transition Medic Medical Weight Loss Linkedin Audio Stamps 01:42 – Meet Joseph Zucchi, PA, clinical supervisor at a comprehensive weight management clinic with an on-site food store. 04:35 – What is oral Wegovy and how does it compare to injectable semaglutide in terms of efficacy and weight loss? 07:21 – The reformulation that makes oral Wegovy different from Rybelsus and why absorption matters. 10:22 – How to take oral Wegovy correctly: timing, dosing instructions, and common mistakes to avoid. 12:02 – Who should consider oral Wegovy and who might be better off sticking with injections? 13:45 – Side effects, dosing transitions, and what to expect when switching from injectable to oral. 22:03 – The importance of specialized care: why working with a weight management expert improves outcomes. 24:00 – Pricing, insurance coverage challenges, and accessibility of oral Wegovy in 2026. All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com Not Sure Where to Start With the Podcast? I’ve Got You.Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you. Support the show

    29 min
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About

Matthea Rentea MD leads discussions on obesity and chronic weight management. Her guests range from experts in the fields that intersect with obesity and wellness, to individuals successful in their weight journey. She is a Board certified Internal Medicine and Diplomate of the American Board of Obesity Medicine and founder of the Rentea Metabolic Clinic, a Telehealth clinic for residents of the state of Indiana and Illinois that helps comprehensively with weight management. This podcast is for information and education purposes only. No medical advice is being given. Please talk to your physician for what is right for you. 

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