Harmony Hub Health

Michele
  • 4.6 (8)
  • MEDICINE
  • UPDATED BIWEEKLY

Functional Medicine, Hormone Health and Weight Loss with Michele Postol, CRNP 

  1. 2D AGO

    The Future Is Tiny: Peptides & the Power of Cellular Signaling

    Send a text Your body doesn’t need louder interventions; it needs clearer instructions. We take you inside the “tiny but mighty” world of peptides—short amino acid signals that guide repair, shift inflammation, and nudge gene expression—showing how precision messaging can outperform brute‑force approaches. From GH‑axis tools like CJC‑1295 with ipamorelin and sermorelin/tesamorelin to tissue repair favorites BPC157 and TB500, and from metabolic support with MOTS‑C to collagen‑centric GHK‑Cu and fat‑focused AOD9604, we map mechanisms to real outcomes without the hype. Quality is the quiet variable that changes everything. We unpack why two vials with the same label can act differently and outline the testing that matters—HPLC, mass spectrometry, endotoxin, sterility, and third‑party validation—so you can separate medical‑grade signals from guesswork. Then we connect the dots between signaling and terrain: thyroid status, insulin control, sleep architecture, protein intake, cortisol rhythm, gut integrity, and micronutrients set receptor sensitivity and downstream capacity. You cannot out‑signal poor physiology, and more dosing is not better—receptor saturation, desensitization, fluid shifts, glucose volatility, and insomnia are the predictable costs of pushing too hard. We share practical stacking strategies that respect biology: pairing GH secretagogues with sleep and glucose optimization; combining BPC157 and TB500 alongside progressive loading; aligning MOTS‑C with resistance training and nutrient sufficiency; and using GHK‑Cu where collagen signaling has the substrate to rebuild. Aging weakens the body’s communication channels, but the right peptides can reintroduce instruction so tissue organizes, metabolism adapts, and recovery improves—not by forcing change, but by reminding the system what to do. Ready to approach regeneration intelligently? Start with evaluation, not a shopping cart. Subscribe, share this episode with someone stuck in trial‑and‑error, and leave a review telling us which peptide topic you want us to go deeper on next. Support the show linktr.ee/harmonyhubhealth Find me at www.harmonyhubhealth.com Email me at michele@harmonyhubhealth.com

    19 min

  2. FEB 16

    Why Vampires Age Better (Hint: It’s PRP)

    Send a text Your skin is not just aging on the surface; it’s changing at the cellular level. We explore how platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) can reawaken collagen, boost circulation, and restore sensitivity by working with your biology, not against it. From the vampire facial that pairs microneedling with growth factors to the vampire facelift that blends hyaluronic filler for lift and PRP for tissue quality, we unpack what each option actually does—and when to use them together for results that look alive, not “done.” We also dive into hair restoration with PRP, explaining how growth factors stimulate dermal papilla cells, extend the anagen phase, and improve scalp vascularity for early thinning, postpartum shedding, and androgenic patterns. Then we get precise about PRP vs PRF: fast signal flare versus slow-release scaffold, and why that timing matters for thin skin, tear troughs, and delicate areas. Along the way, we compare biostimulation to volume replacement so you can decide whether you need structure, regeneration, or a strategic mix. If you’ve wondered whether “collagen-boosting” serums can rival procedures, we break the myth. The stratum corneum keeps big molecules out, so most topicals hydrate the surface but don’t reach fibroblasts in the dermis. Real collagen induction comes from controlled injury and biologic signaling—think microneedling, PRP/PRF, fractional RF, lasers, biostimulators, and consistent retinoids. We connect the dots to whole-body health too: protein, vitamin C, copper, zinc, hormones, cortisol, thyroid, and blood sugar all shape your results because biology always wins. Ready to choose smarter? Book a personalized regenerative consult at Harmony Hub Health to assess skin thickness, collagen health, hormones, and goals—and discover whether PRF, PRP, HA filler, or a combination fits you best. If this helped you see past the hype, follow, share with a friend, and leave a review so more people can find science-first aesthetics. Support the show linktr.ee/harmonyhubhealth Find me at www.harmonyhubhealth.com Email me at michele@harmonyhubhealth.com

    24 min

  3. FEB 9

    Let’s Talk About Female Pleasure (With Science)

    Send a text Pain with intimacy, low desire, and dryness aren’t “just hormones” to quietly tolerate—they’re signals your body needs support. We walk through a clear, science-led path to restore sensation, arousal, and confidence using platelet-rich plasma and the OShot protocol, a precise, regenerative treatment that uses your own biology to improve blood flow, nerve signaling, and tissue quality. Across this candid conversation, we explain how PRP is prepared, where it’s placed, and why anatomical precision matters for outcomes. You’ll hear practical benefits women report—from stronger, more reliable orgasms to relief from vaginal dryness, atrophy, and even mild stress urinary incontinence—and how results typically unfold over two to three months and can last 12 to 18 months. We also share what the procedure feels like, how we keep it comfortable with topical and local anesthetic, and the minimal downtime required. Because libido isn’t one-dimensional, we broaden the lens to whole-person care. We talk hormone balance for women—including the role of testosterone—plus thyroid and adrenal health, pelvic floor therapy, core and breath work, peptides, and stress and sleep strategies that support the brain’s arousal pathways. If you’re wondering whether you’re a good candidate, we outline clear indicators: reduced sensation, difficulty with orgasm, dryness or discomfort, or a desire for a non-hormonal option that centers real physiology over quick fixes. Female sexual wellness is healthcare, not vanity. If something has shifted for you and you want a plan that respects your body and your life, we’re here to help. Subscribe, share this with a friend who needs it, and leave a review so more women can find evidence-based options for restoring comfort, connection, and joy. Support the show linktr.ee/harmonyhubhealth Find me at www.harmonyhubhealth.com Email me at michele@harmonyhubhealth.com

    11 min

  4. FEB 2

    The Men’s Regenerative Playbook: How to Build Your Best Penis Ever (Backed by Science)

    Send a text Tired of quick fixes that fade when stress hits or timing isn’t perfect? We pull back the curtain on a regenerative approach to men’s sexual health that rebuilds performance from the inside out. Instead of chasing a pill, we map a clear plan to restore blood flow, nerve function, tissue quality, and hormonal balance so you can count on firmness, sensitivity, and confidence. We start with the fundamentals: erections are vascular and neurological events. That’s why platelet-rich plasma takes center stage. PRP brings platelet-derived growth factors to drive angiogenesis for better circulation, neurogenesis for sharper sensation, and tissue remodeling for stronger expansion and rigidity. We also talk candidly about girth and functional length, including how men with vascular compromise or Peyronie’s disease can see meaningful gains when fibrosis calms and elasticity returns. Then we level up with shockwave therapy. Acoustic waves trigger nitric oxide release, boost endothelial function, and break microvascular calcifications, priming tissue so PRP signals hit harder and last longer. Next, we address testosterone as the non-negotiable fuel for nitric oxide, smooth muscle tone, libido, mood, and recovery. Without it, regenerative work underperforms. Peptides round out the stack: PT-141 flips the desire switch, while GH-supporting, nitric-oxide, and neurosupportive peptides refine repair, blood flow, and brain-body connection. Finally, we share the Apex men’s membership: a year-long, supervised plan that integrates TRT, targeted peptides, PRP for sexual function and hair restoration, shockwave therapy, metabolic support, and practical lifestyle tools. The aim isn’t to chase youth; it’s to own your prime with science that sustains performance and wellbeing. If you’re ready to build your best penis ever and strengthen your overall health, subscribe, share this episode with someone who needs it, and leave a review with your top question about regenerative options. Support the show linktr.ee/harmonyhubhealth Find me at www.harmonyhubhealth.com Email me at michele@harmonyhubhealth.com

    13 min

  5. JAN 26

    Platelet-Rich Plasma (PRP): From Pain Relief To Skin, Hair, And Sexual Wellness

    Send a text What if the strongest regenerative medicine tool isn’t a pill or a filler, but your own biology? We dive deep into platelet-rich plasma—how it’s prepared, why technique matters, and where it truly shines for pain, skin, hair, and sexual wellness. You’ll hear a clear, step-by-step view of PRP’s science, from platelets and growth factors like PDGF, TGF beta, VEGF, EGF, and IGF-1 to the role they play in signaling tissue repair, building collagen, and improving circulation. We walk through the full process: drawing and spinning blood, protecting platelet integrity, and matching preparation to the goal—joint injections for osteoarthritis and tendinopathies, microneedling for texture and tone, scalp protocols for early thinning and postpartum shedding, and O-Shot/P-Shot strategies that support vascular health, sensitivity, and erectile function. Along the way, we share why spin speed and timing shape outcomes, how heated PRP/PRF creates a natural biostimulatory matrix for under-eye and crepey skin, and why PRP differs from quick fixes like steroids or instant glow treatments. Results are gradual and meaningful when stacked with complementary tools. We break down how shockwave therapy, peptides, nutrient optimization, hormone support, and stable blood sugar create the environment where regeneration compounds. PRP isn’t stem cells, isn’t one-size-fits-all, and isn’t effective when poorly prepared—so we focus on precision, personalization, and a whole-body plan that turns biology into outcomes. Ready to move beyond temporary relief and invest in smarter healing? Subscribe, share with a friend who needs real answers, and book your regenerative consultation to explore whether PRP is right for you. Support the show linktr.ee/harmonyhubhealth Find me at www.harmonyhubhealth.com Email me at michele@harmonyhubhealth.com

    15 min

  6. JAN 19

    Regenerative Shockwave Therapy: Restoring the Conditions for Healing

    Send a text I continue our Regenerative Treatment series with Shockwave Therapy. Pain isn’t the enemy—it’s the message your body sends when healing has stalled. We unpack why so many “normal” scans still coexist with real pain and how a regenerative approach restores the biology of repair. With a clear, practical walk‑through of extracorporeal shockwave therapy (ESWT), we share how targeted mechanical stimulation can reboot microcirculation, remodel stubborn scar tissue, calm irritated nerves, and boost mitochondrial energy so tissues can finally complete the healing process. We explain mechanotransduction in plain language and show how precision matters: tendons need deeper, focused energy, muscles respond to broader input, nerves need careful neuromodulation, and scar tissue requires disruption and alignment. You’ll hear how ESWT promotes angiogenesis through VEGF and nitric oxide signaling, activates fibroblasts for collagen remodeling, reduces substance P to dial down pain amplification, and elevates ATP production to power repair. From plantar fasciitis and rotator cuff pain to Achilles tendinopathy, pelvic floor dysfunction, erectile dysfunction, and peripheral neuropathy, we outline where shockwave shines when recovery has plateaued. This is not a replacement for physical therapy—it’s the foundation that makes therapy stick. We talk strategy for stacking ESWT with PT, IV nutrient therapy, peptides, lymphatic support, infrared sauna, and PRP to create a responsive environment for growth factors and long‑term gains. Sessions are quick—often 10 to 15 minutes—with mild discomfort and no downtime, and improvements build over weeks as circulation, signaling, and tissue quality normalize. Curious whether ESWT could help you avoid surgery or finally move past chronic stiffness? Test your response with a $49 trial at Harmony Hub Health, or reach out for a free consult. Subscribe, share this with someone stuck on a rehab plateau, and leave a review to help more listeners find regenerative solutions that work. Support the show linktr.ee/harmonyhubhealth Find me at www.harmonyhubhealth.com Email me at michele@harmonyhubhealth.com

    10 min

  7. JAN 12

    If Regeneration Had a Group Chat: Wharton’s Jelly, Exosomes, and Stem Cells Explained

    Send a text Think healing that starts at the root and scales from a single joint to your whole system. We break down functional regeneration—pairing the “why” of functional medicine with the “how” of regenerative tools—so you understand when to use stem cells, why exosomes matter for cellular messaging, and where Wharton’s jelly fits for durable structural support. No hype, no shortcuts, just clear guidance on building real resilience instead of chasing short-term pain relief. You’ll hear how mesenchymal stem cells act as repair coordinators rather than replacement parts, why exosomes deliver fast, precise instructions that speed recovery, and how Wharton’s jelly provides a potent environment for longer-lasting change in worn joints. We also step into the systems layer with IV stem cell infusions, explaining homing, paracrine signaling, and the role of immune modulation in chronic inflammation and longevity. Along the way, we separate local repair from global reset, outline when each tool belongs, and show how stacking therapies can amplify outcomes. The throughline is the terrain: hydration, nutrients, mitochondrial function, and oxidative stress determine whether any regenerative therapy can work. By preparing the body with targeted IV nourishment and functional medicine principles, we raise the signal-to-noise ratio so cells can respond. Expect practical takeaways on sequencing care, setting realistic expectations, and aligning interventions with goals like joint resilience, faster recovery, and systemic balance. If you’ve been told surgery is your only option or your “normal” labs don’t match how you feel, this is your map to smarter regeneration. Subscribe, share with someone who needs options beyond band-aid fixes, and leave a review with your top question about joints, exosomes, or IV stem cells—we may feature it in our next deep dive. Support the show linktr.ee/harmonyhubhealth Find me at www.harmonyhubhealth.com Email me at michele@harmonyhubhealth.com

    16 min

  8. JAN 5

    Regenerative Medicine: The Science of Helping the Body Remember How to Heal

    Send a text A simple question at a noisy gym—“What’s that?”—sparked a full reset on how we explain regenerative care. We zoom out from jargon and get practical about what regenerative medicine is, who it helps, and why pairing it with functional medicine can create the conditions for real healing. Instead of managing symptoms, we focus on restoring function, structure, and cellular health in the tissues that often stall: tendons, ligaments, joints, nerves, and chronically inflamed areas. We walk through the modern toolbox in plain language. Shockwave for stubborn pain and poor blood flow. Peptides as cellular messengers that nudge repair and resilience. PRP and PRF to harness your own growth factors for joints, skin, and hair. Exosomes to refine cell-to-cell communication and amplify results. Ozone to support oxygen use, immune balance, and metabolism. Float therapy to reset the nervous system so the body can actually heal. You’ll hear how these therapies fit together, why the right sequence matters, and how we match the tool to the person rather than force a one-size plan. Regenerative aesthetics follows the same biology. Think Sculptra for collagen biostimulation, PRP/PRF under-eye refresh, and exosomes paired with microneedling or radiofrequency to improve texture and integrity over time. We also explore prevention and healthspan—using regenerative strategies before breakdown, extending function and mobility, and filling the gap between “your labs are fine” and “you need surgery.” Our approach lives inside an ecosystem: functional testing, metabolic and hormonal support, nutrient optimization, nervous system regulation, and lifestyle alignment. If you’re tired of being told to live with it, this conversation offers clarity and options. Subscribe, share with someone who needs hope, and leave a review with the one question you still want answered about regenerative medicine. Support the show linktr.ee/harmonyhubhealth Find me at www.harmonyhubhealth.com Email me at michele@harmonyhubhealth.com

    16 min
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Ratings & Reviews

4.6
out of 5
8 Ratings

About

Functional Medicine, Hormone Health and Weight Loss with Michele Postol, CRNP 

Information

  • Creator
    Michele
  • Years Active
    2024 - 2026
  • Episodes
    95
  • Rating
    Explicit
  • Copyright
    © 2026 Harmony Hub Health
  • Show Website
    Harmony Hub Health

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