Hormones & Hope with Dr. Chhaya

Chhaya Makhija, MD

Welcome to Hormones and Hope, the podcast where we bridge science and wellness for every listener. I’m Dr. Chhaya Makhija, a triple board-certified endocrinologist, lifestyle medicine specialist, and educator/speaker practicing in California. After nearly two decades of helping patients decode their health, I created this podcast to give you trusted, evidence-based insights—delivered with clarity, compassion, and real-life relevance. Let's experience the intersection of clinical endocrinology & lifestyle empowerment.

  1. 3h ago

    Vaping, Marijuana & Air Pollution: What They're Really Doing to Your Lungs

    In this episode of Hormones & Hope, Dr. Chhaya Makhija welcomes pulmonologist Dr. Vijay Balasubramanian for an in-depth discussion about respiratory health, environmental exposures, and the everyday habits that shape our lung function over a lifetime. We often focus on improving our heart health, lowering cholesterol, managing blood sugar, or losing weight, but healthy lungs are just as essential to living well. Every breath fuels our body with oxygen, making lung health a cornerstone of overall wellness. Dr. Vijay shares his expertise on how the lungs work, why they naturally change as we age, and how conditions like obesity, sleep apnea, and cardiovascular disease can all influence the way we breathe. He also explains why shortness of breath is never a symptom to ignore and why finding its underlying cause is so important. The conversation takes a deep dive into the modern threats to lung health, including air pollution, wildfire smoke, vaping, marijuana use, and occupational exposures. Dr. Vijay discusses how these factors can contribute to inflammation, chronic lung disease, pulmonary hypertension, and permanent lung damage, while offering practical strategies to reduce your risk. From avoiding smoking and vaping to staying physically active and minimizing harmful exposures, small choices today can have a lasting impact on your respiratory health for years to come. If you're looking to better understand your lung health, protect your breathing as you age, or learn how everyday exposures affect your body, be sure to check out this episode. Dr. Vijay Balasubramanian is the Founder/ Medical Director of Valley Advanced Lung Diseases Institute (VALDI) in Fresno. He is Board Certified in Pulmonary Medicine and specializes in Advanced lung diseases such as Interstitial Lung disease and Pulmonary vascular disease. VALDI is the first of its kind in the central valley of California. Its goal is to provide Access to care for Advanced Lung diseases - Diagnosis & management. Through its collaboration with Stanford Lung Transplant Program, patients are also able to be seen locally for consideration of Lung Transplantation if needed. He earned his medical degree at Stanley Medical College and completed postgraduate fellowship training in the United Kingdom (MRCP UK) and the Medical College of Wisconsin. He recently completed his Academic tenure as Professor of Medicine at UCSF Fresno. At UCSF Fresno, he established a nationally renowned Pulmonary Hypertension Program. He is nationally recognized in the field of Pulmonary Hypertension with extensive academic accomplishments including Research and publications. He is the recipient of multiple Teaching awards. He has shown strong commitment in organizing and supporting his patient support group for over 15 years. Download the Free Guide 'Your Health on GLP-1' Here: https://dr-chhaya.myflodesk.com/glp1 Follow Dr. Chhaya Makhija here: https://www.instagram.com/chhayamakhijamd/ https://www.facebook.com/unifiedendocrine https://unifiedendocrinecare.com/ https://www.youtube.com/@chhayamakhijamd https://www.linkedin.com/in/chhayamakhijamd/ Email: connect@unifiedendocrinecare.com Follow Dr. Vijay Balasubramanian here: https://www.valdiinc.com/aboutvijaybalasubramanian https://www.linkedin.com/company/valdiinc/ Disclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance. 🔔 Don’t forget to like, subscribe, and hit the bell icon!

    30 min
  2. Jun 25

    IBS, Anxiety & Depression: The Link Between Hormone Imbalance and Gut Microbiome

    In this episode of Hormones & Hope, Dr. Chhaya Makhija sits down with Dr. Melissa Mondala, Family & Integrative Medicine Specialist, for a powerful conversation about the connection between lifestyle, gut health, and emotional well-being. Drawing from both personal experience and years of clinical practice, Dr. Mondala explains how the gut and brain work together, why nutrition and exercise are essential for mental health, and how sleep, stress management, and social connection can help build emotional resilience. She also shares practical tips for making healthy habits stick, overcoming setbacks, and creating routines that work in real life—not just for a few weeks, but for the long term Whether you're supporting your own mental health or helping someone you love, this episode offers hope, practical guidance, and a reminder that meaningful change often starts with simple daily choices. Download the Free Guide 'Your Health on GLP-1' Here: https://dr-chhaya.myflodesk.com/glp1 Follow Dr. Chhaya Makhija here: https://www.instagram.com/chhayamakhijamd/ https://www.facebook.com/unifiedendocrine https://unifiedendocrinecare.com/ https://www.youtube.com/@chhayamakhijamd https://www.linkedin.com/in/chhayamakhijamd/ Email: connect@unifiedendocrinecare.com Follow Dr. Mondala here: https://www.instagram.com/drmelissamondala/ https://drlifestyle.org/ https://www.instagram.com/drlifestyleclinic/ Dr. Melissa Mondala, MD is a double board-certified physician in Family Medicine and Lifestyle Medicine, with advanced fellowships in training in integrative psychiatry and integrative medicine. Dr. Mondala is the President and co-founder of Dr. Lifestyle Clinic in Newport Beach — the first Lifestyle and Integrative Direct Primary Care and Rheumatology clinic The clinic has been recognized as a Public Health Site of Excellence and she is a best-selling author of Embody Lifestyle Medicine and well sought out speaker. Disclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance. 🔔 Don’t forget to like, subscribe, and hit the bell icon! .

    46 min
  3. Jun 18

    Statins, Calcium Score & Cholesterol: What You Need to Know About Preventing Heart Disease

    In Part 2 of this powerful conversation, Dr. Chhaya Makhija sits down with preventive cardiologist Dr. Sourbha S. Dani to discuss how we can identify and prevent heart disease before it becomes a life-changing event. Together, they break down the screening tests, lab markers, and imaging studies that can help uncover cardiovascular risk years before symptoms develop. From ApoB and Lipoprotein(a) to coronary calcium scores, insulin resistance, statins, and lifestyle interventions, this episode provides a practical roadmap for anyone looking to take a proactive approach to heart health. Dr. Chhaya also shares her perspective as a preventive endocrinologist, highlighting the metabolic factors that often drive cardiovascular disease and why early intervention matters. If you have a family history of heart disease, elevated cholesterol, diabetes, or simply want to optimize your long-term health, this episode is packed with actionable insights. Download the Free Guide 'Your Health on GLP-1' Here: https://dr-chhaya.myflodesk.com/glp1 Follow Dr. Chhaya Makhija here: https://www.instagram.com/chhayamakhijamd/ https://www.facebook.com/unifiedendocrine https://unifiedendocrinecare.com/ https://www.youtube.com/@chhayamakhijamd https://www.linkedin.com/in/chhayamakhijamd/ Email: connect@unifiedendocrinecare.com Follow Dr. Dani here: https://www.linkedin.com/in/sourbhadani/ https://physicians.lahey.org/details/4012 Dr. Dani is a non-invasive cardiologist with a special focus on prevention and premature heart disease at Lahey Hospital and Medical Center in Burlington, Massachusetts. He serves as the Program Director for the Cardiovascular Fellowship, Director of Inpatient Cardiac Services, Director of the Adult Congenital Heart Disease Center, and Co-Director of the region's first South Asian Metabolic Program. He is also an Associate Professor at the University of Massachusetts Medical School and Tufts University. In addition to his clinical and academic roles, Dr. Dani is a cardiovascular outcomes and healthcare economics researcher, collaborating with the Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center in Boston and the Center for Cardiovascular Research (CVER) at Tufts University. Disclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance. 🔔 Don’t forget to like, subscribe, and hit the bell icon!

    35 min
  4. Jun 11

    From Ethnicity to Lifestyle: Understanding Heart Disease Risk in South East Asians

    In Part 1 of this two-part series, Dr. Chhaya Makhija sits down with preventive cardiologist Dr. Sourbha Dani to discuss the growing epidemic of premature heart disease in South Asian communities around the world. Dr. Dani explains why many South Asians develop diabetes, high blood pressure, and heart disease at younger ages, why BMI can be misleading, and why being "healthy on paper" doesn't always tell the full story. He also shares how lifestyle choices can dramatically influence long-term risk—even in individuals with a strong family history of cardiovascular disease. The discussion covers the concept of the "thin-fat phenotype," where individuals may appear lean while carrying excess visceral fat and significant metabolic risk.  Next week, Part 2 dives into advanced testing, cholesterol markers, risk assessment tools, statins, and the evolving role of GLP-1 medications in cardiovascular prevention. If you're interested in optimizing your metabolic health, understanding your cardiovascular risk, or learning how to prevent disease before it starts, this episode is a must-listen. Download the Free Guide 'Your Health on GLP-1' Here: https://dr-chhaya.myflodesk.com/glp1 Follow Dr. Chhaya Makhija here: https://www.instagram.com/chhayamakhijamd/ https://www.facebook.com/unifiedendocrine https://unifiedendocrinecare.com/ https://www.youtube.com/@chhayamakhijamd https://www.linkedin.com/in/chhayamakhijamd/ Email: connect@unifiedendocrinecare.com Follow Dr. Dani here: https://www.linkedin.com/in/sourbhadani/ https://physicians.lahey.org/details/4012 Dr. Dani is a non-invasive cardiologist with a special focus on prevention and premature heart disease at Lahey Hospital and Medical Center in Burlington, Massachusetts. He serves as the Program Director for the Cardiovascular Fellowship, Director of Inpatient Cardiac Services, Director of the Adult Congenital Heart Disease Center, and Co-Director of the region's first South Asian Metabolic Program. He is also an Associate Professor at the University of Massachusetts Medical School and Tufts University. In addition to his clinical and academic roles, Dr. Dani is a cardiovascular outcomes and healthcare economics researcher, collaborating with the Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center in Boston and the Center for Cardiovascular Research (CVER) at Tufts University. Disclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance. 🔔 Don’t forget to like, subscribe, and hit the bell icon!

    39 min
  5. Jun 4

    Triple Agonists: The Next Big Thing in GLP-1 & Metabolic Medicine?

    In this episode of Hormones and Hope, Dr. Chhaya Makhija breaks down one of the most rapidly evolving areas of modern medicine: GLP-1 receptor agonists. With new medications, expanding FDA approvals, and growing conversations about weight loss, diabetes, longevity, and metabolic health, it can be difficult to separate evidence-based science from social media hype. Dr. Makhija explains the differences between semaglutide, tirzepatide, and the highly anticipated triple agonist retatrutide while helping listeners understand what we know today—and what remains under investigation. She also discusses why personalized care matters when prescribing GLP-1 medications, how these therapies may impact long-term health beyond weight loss, and why patients should be cautious about compounded or unapproved versions of emerging drugs. Whether you're currently taking a GLP-1 medication, considering one, or simply curious about the future of metabolic medicine, this episode provides a practical, science-backed overview of where the field stands in 2026. Sign Up for The M3 Masterclass with Dr.  Makhija: https://zoom.us/meeting/register/llQXKQSGRCKVpZBMHoqb2A#/ Download the Free Guide 'Your Health on GLP-1' Here: https://dr-chhaya.myflodesk.com/glp1 Follow Dr. Chhaya Makhija here: https://www.instagram.com/chhayamakhijamd/ https://www.facebook.com/unifiedendocrine https://unifiedendocrinecare.com/ https://www.youtube.com/@chhayamakhijamd https://www.linkedin.com/in/chhayamakhijamd/ Email: connect@unifiedendocrinecare.com Disclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance. 🔔 Don’t forget to like, subscribe, and hit the bell icon!

    19 min
  6. May 21

    Starting GLP-1 Medications: How to Dose, Up-Titrate & Reduce Side Effects of GLP-1

    Starting a GLP-1 medication can feel overwhelming, especially with so much misinformation online about dosing, side effects, and “maximum” doses. In this episode, Dr. Chhaya Makhija explains how GLP-1 dose titration actually works and why more medication is not always better. From semaglutide medications like Ozempic and Wegovy to tirzepatide options like Mounjaro and Zepbound, she shares how she approaches dosing with her own patients, what signs she monitors, and why individualized care matters so much in metabolic health. She also discusses body composition, inflammation, side effect management, oral GLP-1 medications, and the importance of ongoing communication with your healthcare provider throughout your journey. Whether you’re considering starting a GLP-1 medication, currently adjusting your dose, or simply trying to better understand how these medications work, this episode offers a realistic approach to metabolic health and weight management. Sign Up for The M3 Masterclass with Dr.  Makhija: https://zoom.us/meeting/register/llQXKQSGRCKVpZBMHoqb2A#/ Download the Free Guide 'Your Health on GLP-1' Here: https://dr-chhaya.myflodesk.com/glp1 Follow Dr. Chhaya Makhija here: https://www.instagram.com/chhayamakhijamd/ https://www.facebook.com/unifiedendocrine https://unifiedendocrinecare.com/ https://www.youtube.com/@chhayamakhijamd https://www.linkedin.com/in/chhayamakhijamd/ Email: connect@unifiedendocrinecare.com Disclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance. 🔔 Don’t forget to like, subscribe, and hit the bell icon!

    20 min
  7. May 14

    Walking Isn’t Enough: The Best Exercises to Increase Bone Density

    In this episode of Hormones and Hope, Dr. Chhaya Makhija sits down with physical therapist and Onero-certified specialist Dr. Robert Pauline to discuss one of the most common concerns among women and aging adults: low bone density. From osteopenia and osteoporosis to muscle loss, falls, fractures, and strength training, this episode dives deep into how evidence-based resistance training can help improve strength, balance, confidence, and even bone density.  Dr. Robert shares insights from the groundbreaking LIFTMOR trial, explains why walking alone is not enough to protect your bones, and discusses how properly supervised strength training can completely change the trajectory of aging. You’ll also hear practical advice on how to safely begin lifting weights, why balance and foot stability matter more than people realize, and how younger generations are already showing signs of poor bone health due to lifestyle habits, low-calorie diets, and inactivity. Whether you’re in your 30s, 50s, or beyond, this episode offers practical insight into how movement, resistance training, nutrition, and consistency can support lifelong bone health. Sign Up for The M3 Masterclass with Dr.  Makhija: https://zoom.us/meeting/register/llQXKQSGRCKVpZBMHoqb2A#/registration Follow Dr. Chhaya Makhija here: https://www.instagram.com/chhayamakhijamd/ https://www.facebook.com/unifiedendocrine https://unifiedendocrinecare.com/ https://www.youtube.com/@chhayamakhijamd https://www.linkedin.com/in/chhayamakhijamd/ Email: connect@unifiedendocrinecare.com Download Free Guides/ Resources here: https://linktr.ee/chhayamakhijamd Follow Dr. Robert Pauline here: https://robbypauline.com/ https://www.facebook.com/RobbyPT https://www.instagram.com/rpaulinept/ LIFTMOR Trial  https://pubmed.ncbi.nlm.nih.gov/28975661/ Disclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance. 🔔 Don’t forget to like, subscribe, and hit the bell icon!

    39 min
  8. Apr 30

    3 Key Lessons on Hormones, Muscle & Metabolic Health From a Women’s Health Summit

    In this episode, Dr. Chhaya Makhija reflects on an energizing week in San Francisco and the Bay Area, where she spoke at the Live Long Women’s Health Summit and participated in a Women’s Wellness Lab.  Surrounded by experts in bone health, hormones, and nutrition, she also spent meaningful time connecting with respected colleagues and caring for patients, making it a deeply impactful experience both professionally and personally. She shares three insights that stayed with her long after the week ended—grounded, practical shifts that go beyond trends and focus on what truly supports your strength, energy, and long-term vitality. This episode is a reminder that lasting health isn’t built through extremes, but through small, intentional actions practiced consistently over time. If you’ve been feeling overwhelmed by conflicting advice or unsure where to begin, this conversation helps bring clarity back to the fundamentals. If this episode resonated with you, share it with someone who could use a simple and clear starting point in their health journey. Subscribe for more conversations on hormones, metabolism, and long-term wellness, and consider leaving a review to help others discover the show. Sign Up for The M3 Masterclass with Dr.  Makhija: https://zoom.us/meeting/register/llQXKQSGRCKVpZBMHoqb2A#/registration Download the Free Guide 'Your Health on GLP-1' Here: https://dr-chhaya.myflodesk.com/glp1 Follow Dr. Chhaya Makhija here: https://www.instagram.com/chhayamakhijamd/ https://www.facebook.com/unifiedendocrine https://unifiedendocrinecare.com/ https://www.youtube.com/@chhayamakhijamd https://www.linkedin.com/in/chhayamakhijamd/ Email: connect@unifiedendocrinecare.com Download Free Guides/ Resources here: https://linktr.ee/chhayamakhijamd Disclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance. 🔔 Don’t forget to like, subscribe, and hit the bell icon!

    17 min
5
out of 5
7 Ratings

About

Welcome to Hormones and Hope, the podcast where we bridge science and wellness for every listener. I’m Dr. Chhaya Makhija, a triple board-certified endocrinologist, lifestyle medicine specialist, and educator/speaker practicing in California. After nearly two decades of helping patients decode their health, I created this podcast to give you trusted, evidence-based insights—delivered with clarity, compassion, and real-life relevance. Let's experience the intersection of clinical endocrinology & lifestyle empowerment.

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