Authentic and Agentic with Jayson Manship

IBJ Media Podcast Network
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AI is reshaping the world at a pace humanity has never seen, and the real challenge is not simply understanding the technology. It is learning how to remain deeply human while everything around us accelerates. Authentic & Agentic is the place where leaders come to make sense of that tension. Hosted by serial entrepreneur Jayson Manship, the show pairs clear analysis with honest conversation and real examples you can put into practice. Every episode looks at how AI shows up in the real world, from boardrooms to classrooms to kitchen tables, and explores what it means to build, lead and love in a time shaped by algorithms. The hard things are yet to come. It is time to lean in.

  1. 8H AGO

    How Eli Lilly Is Scaling AI Across Drug Discovery, Manufacturing and Commercial Operations

    At Eli Lilly’s corporate center in Indianapolis, Authentic and Agentic host Jayson Manship speaks with Tim Coleman, Lilly's Chief Technical Officer and Thomas Fuchs, Lilly's Chief AI Officer, about how the global pharmaceutical company made artificial intelligence a strategic priority. The discussion explores how leadership aligned around AI as a long-term transformation, not a short-term experiment. Coleman outlines three pillars that built Lilly’s foundation: experimentation, governance and education. From structured alpha and beta testing to executive education with Purdue University’s Daniels School of Business, the company focused on learning before scaling. Fuchs explains why machine learning is built on repeated failure and how Lilly’s decades of successful and failed experiments create a unique data advantage. The episode highlights applications across the pharmaceutical value chain, including molecular design, digital twins in manufacturing and internally developed AI models. The conversation also addresses executive sponsorship, AI governance, global regulation and the importance of education to remain competitive in the global AI race. For business leaders, the takeaway is clear: lean into your core strengths, focus on real value and ensure leadership engagement at the highest level. Authentic and Agentic is part of the IBJ Media Podcast Network and examines the human side of AI.

    39 min
  2. Super Bowl AI ads, ‘SaaS apocalypse’ and Indiana tech panel

    FEB 10

    Super Bowl AI ads, ‘SaaS apocalypse’ and Indiana tech panel

    Host Jayson Manship breaks down the impact of artificial intelligence on culture and the economy on this episode of Authentic and Agentic. Manship analyzes the 23% of Super Bowl commercials that used AI and the market selloff sparked by Anthropic’s new software capabilities. He also covers a Blizzard Entertainment union contract that limits unchecked automation. The episode includes a panel discussion from a TechPoint event at IU Health. Manship interviews Ian Andrews of Eli Lilly, Cameron Mueller of Data 317 and Kate Harrison of Innovate Map. The group debates the need for critical thinking skills in an AI world and explores how the technology affects entry-level talent.

    53 min
  3. AI Ethics, Human Formation and the Common Good

    FEB 3

    AI Ethics, Human Formation and the Common Good

    Meghan Sullivan and Adam Kronk join the podcast to examine the ethical challenges posed by artificial intelligence. Drawing from philosophy, education and social service work at the University of Notre Dame, they discuss how AI is changing the way people learn, work and understand human dignity. The episode introduces the Institute for Ethics in the Common Good and its DELTA framework, offering a human-centered approach to AI that emphasizes agency, truth and flourishing in a rapidly changing technological world.

    1h 38m
  4. AI, Streaming and the Future of Music with John Loeffler

    JAN 27

    AI, Streaming and the Future of Music with John Loeffler

    ohn Loeffler, composer and former music executive, breaks down how AI and streaming are transforming the music industry. Drawing on his career in advertising music, television scoring and his work on the Pokémon theme, Loeffler explains why streaming royalties upended artist income, how record labels are adapting, and where the system is broken. He also shares his view of AI as a creative tool, not a replacement for human artists, and offers perspective for musicians navigating a rapidly changing business.

    1h 10m
  5. AI, Grit and Education Reform with Don Wettrick

    JAN 20

    AI, Grit and Education Reform with Don Wettrick

    Educator and entrepreneur Don Wettrick reflects on decades in the classroom and what schools must change as AI reshapes learning and work. He shares why students should be taught to see problems as opportunities, how AI can widen the gap between haves and have-nots, and why grit, discernment and real-world creation matter more than grades. The conversation also looks at innovation centers in schools, preparing students for a workforce with fewer entry-level jobs, and helping young people move from consuming content to building something meaningful.

    1h 12m
  6. How AI Is Changing the CFO Role and Financial Planning for Founders

    JAN 13

    How AI Is Changing the CFO Role and Financial Planning for Founders

    Jayson Manship talks with Brady Whitesel, a fractional CFO and former CEO, about how artificial intelligence is reshaping financial planning, accounting and decision-making for founders. The conversation explores the difference between bookkeeping and forward-looking financial modeling, why AI is a productivity multiplier rather than a replacement for CFO judgment, and how leaders should balance speed with discernment. Whitesel also shares how he used AI tools like ChatGPT and Replit to build a functional pizza-rating app for $200, and why financial discipline, accountability and monthly planning remain essential in an AI-driven economy.

    50 min
  7. How AI Is Reshaping Work, Creativity and Community in Indiana

    JAN 6

    How AI Is Reshaping Work, Creativity and Community in Indiana

    Host Jayson Manship is joined by Kevin and Liz Schmidt to discuss how artificial intelligence is changing real work for developers, creators and small businesses. The conversation explores their move from Silicon Valley to Indiana, how AI is improving productivity without replacing people, and why community and communication matter as technology accelerates. Topics include AI in software development, creative workflows at Adobe, quality of life gains from automation, and what young professionals need to stand out in an AI-driven economy.

    53 min
  8. Serial Entrepreneur Explains How to Scale Authenticity

    12/30/2025

    Serial Entrepreneur Explains How to Scale Authenticity

    Spokenote founder and CEO, John Wechsler joins us for a conversation about how Spokenote is using AI to help them create personalized video that can be customized at scale while preserving a sense of authenticity. We'll discuss the future of AI and how we might retain our humanity in a world that continues to be transformed by Artificial Intelligence.

    55 min
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About

AI is reshaping the world at a pace humanity has never seen, and the real challenge is not simply understanding the technology. It is learning how to remain deeply human while everything around us accelerates. Authentic & Agentic is the place where leaders come to make sense of that tension. Hosted by serial entrepreneur Jayson Manship, the show pairs clear analysis with honest conversation and real examples you can put into practice. Every episode looks at how AI shows up in the real world, from boardrooms to classrooms to kitchen tables, and explores what it means to build, lead and love in a time shaped by algorithms. The hard things are yet to come. It is time to lean in.

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