TWiV is a weekly netcast about viruses - the kind that make you sick. Professors Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler and science writer Alan Dove and guests deconstruct viruses, how they cause illness, and dissect the latest research.
Sputnik spat and furin in ferrets
TWiV examines the claim by Brazil’s ANVISA that the Sputnik vaccine contains replication-competent adenovirus, and a role for the furin cleavage site in SARS-CoV-2 spike for efficient reproduction in the respiratory tract, evasion of antiviral IFITM proteins, and transmission in ferrets.
To err is viral
The TWiVmeisters discuss how copy-back defective viral genomes might modulate the clinical outcome of respiratory syncytial virus infection, and detection of antibodies to henipa- and filo-like viruses in Trinidad bats.
COVID-19 clinical update #60 with Dr. Daniel Griffin
In COVID-19 clinical update #60, Daniel Griffin summarizes CDC guidance for summer camps, how to protect yourself when fully vaccinated, updated recommendation for J&J vaccine, declining global case fatality rate, and characterization of post-acute sequelae.
SARS-CoV-2 gets a sense of humoral
A TWiV trio explains a method for sequencing single genomes of SARS-CoV-2 and its use to explore in-host evolution drive by antibody responses, and incidence of cerebral venous thrombosis in COVID-19 patients and vaccine recipients.
COVID-19 clinical update #59 with Dr. Daniel Griffin
Daniel Griffin discusses a front-line health care worker survey, pre-exposure seropositivity and subsequent infection in healthy young adults, fitted filtration efficiency of double masking, BinaxNow rapid in-home antigen test, postvaccination infections in a nursing facility, safety of mRNA vaccine in pregnant women, case control study of Bamlanivimab, no evidence for brain infection in patients with neurolgical symptoms, and mortality among US patients hospitalized with COVID-19.
Encephalitis viruses dine on caveolae
Team TWiV explains how alphaviruses like Western equine encephalitis virus cross into the brain from capillaries by caveolin-mediated transcytosis, and reveal scientists’ incentives and attitudes towards public communication.
Superb except for Amy Rosenfeld
Every regular members are great to listen to except for Amy Rosenfeld. It’s not her voice but the way she speaks (semi-vocal fry) that gives my ears aural COVID-19.
Thank you for such an information packed podcast!
Absolutely love your all your podcasts! You all do such an excellent job of making science even more fascinating. Kudos & thanks for all the time devoted to every show!
Listen to this Podcast
TWIV is a reminder of all that is potentially great about the internet. Not only is Racaniello a world class virologist, he also happens to be a naturally great teacher (I am not his student). The rapport between the regular panelists is engaging and pleasant. The guests are at the cutting edge of the science. Intereated listeners should check out his virology course on You Tube. It's fantastic and free!